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Research Output 1998 2019

2019

Acknowledgements: the Levin/Kile rule

Levin, J. & Kile, B. T., 1 Jan 2019, In : Platelets. 30, 2, 1 p.

Research output: Contribution to journalLetterOtherpeer-review

A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis

van Delft, M. F., Chappaz, S., Khakham, Y., Bui, C. T., Debrincat, M. A., Lowes, K. N., Brouwer, J. M., Grohmann, C., Sharp, P. P., Dagley, L. F., Li, L., McArthur, K., Luo, M. X., Chin, H. S., Fairlie, W. D., Lee, E. F., Segal, D., Duflocq, S., Lessene, R., Bernard, S. & 16 others, Peilleron, L., Nguyen, T., Miles, C., Wan, S. S., Lane, R. M., Wardak, A., Lackovic, K., Colman, P. M., Sandow, J. J., Webb, A. I., Czabotar, P. E., Dewson, G., Watson, K. G., Huang, D. C. S., Lessene, G. & Kile, B. T., 1 Nov 2019, In : Nature Chemical Biology. 15, 11, p. 1057-1066 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Iacobucci, I., Wen, J., Meggendorfer, M., Choi, J. K., Shi, L., Pounds, S. B., Carmichael, C. L., Masih, K. E., Morris, S. M., Lindsley, R. C., Janke, L. J., Alexander, T. B., Song, G., Qu, C., Li, Y., Payne-Turner, D., Tomizawa, D., Kiyokawa, N., Valentine, M., Valentine, V. & 28 others, Basso, G., Locatelli, F., Enemark, E. J., Kham, S. K. Y., Yeoh, A. E. J., Ma, X., Zhou, X., Sioson, E., Rusch, M., Ries, R. E., Stieglitz, E., Hunger, S. P., Wei, A. H., To, L. B., Lewis, I. D., D’Andrea, R. J., Kile, B. T., Brown, A. L., Scott, H. S., Hahn, C. N., Marlton, P., Pei, D., Cheng, C., Loh, M. L., Ebert, B. L., Meshinchi, S., Haferlach, T. & Mullighan, C. G., Apr 2019, In : Nature Genetics. 51, 4, p. 694-704 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Shared roles for Scl and Lyl1 in murine platelet production and function

Chiu, S. K., Orive, S. L., Moon, M. J., Saw, J., Ellis, S., Kile, B. T., Huang, Y., Chacon, D., Pimanda, J. E., Beck, D., Hamilton, J. R., Tremblay, C. S. & Curtis, D. J., 5 Sep 2019, In : Blood. 134, 10, p. 826-835 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2018
15 Citations (Scopus)

Apoptosis in megakaryocytes and platelets: the life and death of a lineage

McArthur, K., Chappaz, S. & Kile, B. T., 8 Feb 2018, In : Blood. 131, 6, p. 605-610 6 p.

Research output: Contribution to journalArticleOtherpeer-review

25 Citations (Scopus)

Apoptotic Caspases: Multiple or Mistaken Identities?

McArthur, K. & Kile, B. T., 1 Jun 2018, In : Trends in Cell Biology. 28, 6, p. 475-493 19 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

63 Citations (Scopus)

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

McArthur, K., Whitehead, L. W., Heddleston, J. M., Li, L., Padman, B. S., Oorschot, V., Geoghegan, N. D., Chappaz, S., Davidson, S., Chin, H. S., Lane, R. M., Dramicanin, M., Saunders, T. L., Sugiana, C., Lessene, R., Osellame, L. D., Chew, T. L., Dewson, G., Lazarou, M., Ramm, G. & 5 others, Lessene, G., Ryan, M. T., Rogers, K. L., Van Delft, M. F. & Kile, B. T., 23 Feb 2018, In : Science. 359, 6378, 12 p., eaao6047.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of Tfrc-mutant mice with microcytic phenotypes

Conway, A. J., Brown, F. C., Rank, G., Kile, B. T., Morton, C. J., Jane, S. M. & Curtis, D. J., 14 Aug 2018, In : Blood Advances. 2, 15, p. 1914-1922 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Diagnosis and treatment of MYH9-RD in an Australasian cohort with thrombocytopenia

Rabbolini, D. J., Chun, Y., Latimer, M., Kunishima, S., Fixter, K., Valecha, B., Tan, P., Chew, L. P., Kile, B. T., Burt, R., Radhakrishnan, K., Bird, R., Ockelford, P., Gabrielli, S., Chen, Q., Stevenson, W. S., Ward, C. M. & Morel-Kopp, M. C., 17 Nov 2018, In : Platelets. 29, 8, p. 793-800 8 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion

Pleines, I., Lebois, M., Gangatirkar, P., Au, A. E., Lane, R. M., Henley, K. J., Kauppi, M., Corbin, J., Cannon, P., Bernardini, J., Alwis, I., Jarman, K. E., Ellis, S., Metcalf, D., Jackson, S. P., Schoenwaelder, S. M., Kile, B. T. & Josefsson, E. C., 12 Jul 2018, In : Blood. 132, 2, p. 197-209 13 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

Tye, H., Yu, C. H., Simms, L. A., de Zoete, M. R., Kim, M. L., Zakrzewski, M., Penington, J. S., Harapas, C. R., Souza-Fonseca-Guimaraes, F., Wockner, L. F., Preaudet, A., Mielke, L. A., Wilcox, S. A., Ogura, Y., Corr, S. C., Kanojia, K., Kouremenos, K. A., De Souza, D. P., McConville, M. J., Flavell, R. A. & 6 others, Gerlic, M., Kile, B. T., Papenfuss, A. T., Putoczki, T. L., Radford-Smith, G. L. & Masters, S. L., 13 Sep 2018, In : Nature Communications. 9, 1, 11 p., 3728.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes

Jiao, Y., Davis, J. E., Rautela, J., Carrington, E. M., Ludford-Menting, M. J., Goh, W., Delconte, R. B., Souza-Fonseca-Guimaraes, F., Koldej, R., Gray, D., Huang, D., Kile, B. T., Lew, A. M., Ritchie, D. S. & Huntington, N. D., 12 Nov 2018, In : Cell Death and Differentiation. 26, p. 1516-1530 15 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

Vince, J. E., De Nardo, D., Gao, W., Vince, A. J., Hall, C., McArthur, K., Simpson, D., Vijayaraj, S., Lindqvist, L. M., Bouillet, P., Rizzacasa, M. A., Man, S. M., Silke, J., Masters, S. L., Lessene, G., Huang, D. C. S., Gray, D. H. D., Kile, B. T., Shao, F. & Lawlor, K. E., 27 Nov 2018, In : Cell Reports. 25, 9, p. 2339-2353 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2017

Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling

Au, A. E., Lebois, M., Sim, S. A., Cannon, P., Corbin, J., Gangatirkar, P., Hyland, C. D., Moujalled, D., Rutgersson, A., Yassinson, F., Kile, B. T., Mason, K. D., Ng, A. P., Alexander, W. S. & Josefsson, E. C., 1 Dec 2017, In : Scientific Reports. 7, 1, 10 p., 14953.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen

Conway, A. J., Brown, F. C., Fullinfaw, R. O., Kile, B. T., Jane, S. M. & Curtis, D. J., 1 Aug 2017, In : Disease Models and Mechanisms. 10, 8, p. 1005-1013 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion

Lindqvist, L. M., Frank, D., McArthur, K., Dite, T. A., Lazarou, M., Oakhill, J. S., Kile, B. T. & Vaux, D. L., 11 Dec 2017, In : Cell Death and Differentiation. 25, p. 782-794 13 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Cell cycle progression dictates the requirement for BCL2 in natural killer cell survival

Viant, C., Guia, S., Hennessy, R. J., Rautela, J., Pham, K., Bernat, C., Goh, W., Jiao, Y., Delconte, R., Roger, M., Simon, V., Souza-Fonseca-Guimaraes, F., Grabow, S., Belz, G. T., Kile, B. T., Strasser, A., Gray, D., Hodgkin, P. D., Beutler, B., Vivier, E. & 2 others, Ugolini, S. & Huntington, N. D., 5 Jan 2017, In : Journal of Experimental Medicine. 214, 2, p. 491-510 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Developmental Stage-Specific Manifestations of Absent TPO/c-MPL Signalling in Newborn Mice

Lorenz, V., Ramsey, H., Liu, Z. J., Italiano, J., Hoffmeister, K., Bihorel, S., Mager, D., Hu, Z., Slayton, W. B., Kile, B. T., Sola-Visner, M. & Ferrer-Marin, F., 1 Jan 2017, In : Thrombosis and Haemostasis. 117, 12, p. 2322-2333 12 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia

Thirant, C., Ignacimouttou, C., Lopez, C. K., Diop, MB., Le Mouël, L., Thiollier, C., Siret, A., Dessen, P., Aid, Z., Rivière, J., Rameau, P., Lefebvre, C., Khaled, M., Leverger, G., Ballerini, P., Petit, A., Raslova, H., Carmichael, C. L., Kile, B. T., Soler, E. & 10 others, Crispino, J. D., Wichmann, C., Pflumio, F., Schwaller, J., Vainchenker, W., Lobry, C., Droin, N., Bernard, O. A., Malinge, S. & Mercher, T., 13 Mar 2017, In : Cancer Cell. 31, 3, p. 452-465 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Loss of Dynamin 2 GTPase function results in microcytic anaemia

Brown, F., Collett, M., Tremblay, C. S., Rank, G., De Camilli, P., Booth, C. J., Bitoun, M., Robinson, P. J., Kile, B. T., Jane, S. M. & Curtis, D. J., Sep 2017, In : British Journal of Haematology. 178, 4, p. 616 - 628 13 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia

Pleines, I., Woods, J., Chappaz, S., Kew, V., Foad, N., Ballester-Beltrán, J., Aurbach, K., Lincetto, C., Lane, R. M., Schevzov, G., Alexander, W. S., Hilton, D. J., Astle, W. J., Downes, K., Nurden, P., Westbury, S. K., Mumford, A. D., Obaji, S. G., Collins, P. W., BioResource, N. & 11 others, Delerue, F., Ittner, L. M., Bryce, N. S., Holliday, M., Lucas, C. A., Hardeman, E. C., Ouwehand, W. H., Gunning, P. W., Turro, E., Tijssen, M. R. & Kile, B. T., 1 Mar 2017, In : Journal of Clinical Investigation. 127, 3, p. 814-829 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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13 Citations (Scopus)

Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia

Yuan, Y., Alwis, I., Wu, M. C. L., Kaplan, Z., Ashworth, K., Bark, D., Pham, A., McFadyen, J., Schoenwaelder, S. M., Josefsson, E. C., Kile, B. T. & Jackson, S. P., 27 Sep 2017, In : Science Translational Medicine. 9, 409, 14 p., eaam5861.

Research output: Contribution to journalArticleResearchpeer-review

2016
10 Citations (Scopus)

Ablation of Type-1 IFN Signaling in Hematopoietic Cells Confers Protection Following Traumatic Brain Injury

Karve, I. P., Zhang, M., Habgood, M., Frugier, T., Brody, K. M., Sashindranath, M., Ek, C. J., Chappaz, S., Kile, B. T., Wright, D., Wang, H., Johnston, L., Daglas, M., Ates, R. C., Medcalf, R. L., Taylor, J. M. & Crack, P. J., 1 Jan 2016, In : eNeuro. 3, 1, 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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37 Citations (Scopus)

Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets

Rowley, J. W., Chappaz, S., Corduan, A., Chong, M. M. W., Campbell, R., Khoury, A., Manne, B. K., Wurtzel, J. G. T., Michael, J. V., Goldfinger, L. E., Mumaw, M. M., Nieman, M. T., Kile, B. T., Provost, P. & Weyrich, A. S., 7 Apr 2016, In : Blood. 127, 14, p. 1743-1751 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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54 Citations (Scopus)

IL-18 production from the NLRP1 inflammasome prevents obesity and metabolic syndrome

Murphy, A. J., Kraakman, M. J., Kammoun, H. L., Dragoljevic, D., Lee, M. K. S., Lawlor, K. E., Wentworth, J. M., Vasanthakumar, A., Gerlic, M., Whitehead, L. W., DiRago, L., Cengia, L., Lane, R. M., Metcalf, D., Vince, J. E., Harrison, L. C., Kallies, A., Kile, B. T., Croker, B. A., Febbraio, M. A. & 1 others, Masters, S. L., 12 Jan 2016, In : Cell Metabolism. 23, 1, p. 155-164 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Loss of PUMA (BBC3) does not prevent thrombocytopenia caused by the loss of BCL-XL (BCL2L1)

Delbridge, A. R. D., Chappaz, S., Ritchie, M. E., Kile, B. T., Strasser, A. & Grabow, S., Sep 2016, In : British Journal of Haematology. 174, 6, p. 962-969 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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17 Citations (Scopus)

Physiological restraint of Bak by Bcl-xL is essential for cell survival

Lee, E. F., Grabow, S., Chappaz, S., Dewson, G., Hockings, C., Kluck, R. M., Debrincat, M. A., Gray, D. H., Witkowski, M. T., Evangelista, M., Pettikiriarachchi, A., Bouillet, P., Lane, R. M., Czabotar, P. E., Colman, P. M., Smith, B. J., Kile, B. T. & Fairlie, W. D., 19 May 2016, In : Genes and Development. 30, 10, p. 1240-1250 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Regulation of platelet lifespan in the presence and absence of thrombopoietin signaling

Lebois, M., Dowling, M. R., Gangatirkar, P., Hodgkin, P. D., Kile, B. T., Alexander, W. S. & Josefsson, E. C., Sep 2016, In : Journal of Thrombosis and Haemostasis. 14, 9, p. 1882-1887 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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22 Citations (Scopus)

Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

Keniry, A., Gearing, L. J., Jansz, N., Liu, J., Holik, A. Z., Hickey, P. F., Kinkel, S. A., Moore, D. L., Breslin, K., Chen, K., Liu, R., Phillips, C., Pakusch, M., Biben, C., Sheridan, J. M., Kile, B. T., Carmichael, C., Ritchie, M. E., Hilton, D. J. & Blewitt, M. E., 18 May 2016, In : Epigenetics and Chromatin. 9, 1, 20 p., 16.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2015
65 Citations (Scopus)

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1beta

Kim, M. L., Chae, J. J., Park, Y. H., De Nardo, D., Stirzaker, R. A., Ko, H-J., Tye, H., Cengia, L., Di Rago, L., Metcalf, D., Roberts, A. W., Kastner, D. L., Lew, A. M., Lyras, D., Kile, B. T., Croker, B. A. & Masters, S. L., 2015, In : Journal of Experimental Medicine. 212, 6, p. 927-938 12 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model

Brown, F. C., Conway, A. J., Cerruti, L., Collinge, J. E., McLean, C., Wiley, J. S., Kile, B. T., Jane, S. M. & Curtis, D. J., 2015, In : Blood. 126, 26, p. 2863-2870 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Aging platelets stimulate TPO production

Kile, B. T., 1 Jan 2015, In : Nature Medicine. 21, 1, p. 11-12 2 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

A novel role for the EMT regulator, snai1, in hematopoiesis and leukemia

Carmichael, C., Goossens, S., Kile, B. & Haigh, J. J., 2015, p. S56. 1 p.

Research output: Contribution to conferencePosterOtherpeer-review

26 Citations (Scopus)

BCL-2 is dispensable for thrombopoiesis and platelet survival

Debrincat, MA., Pleines, I., Lebois, M., Lane, RM., Holmes, ML., Corbin, J., Vandenberg, CJ., Alexander, WS., Ng, AP., Strasser, A., Bouillet, P., Sola-Visner, M., Kile, BT. & Josefsson, EC., 16 Apr 2015, In : Cell Death and Disease. 6, 4, 8 p., e1721.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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27 Citations (Scopus)

Conserved piRNA expression from a distinct set of piRNA cluster loci in Eutherian mammals

Chirn, G., Rahman, R., Sytnikova, Y. A., Matts, J. A., Zeng, M., Gerlach, D., Yu, M., Berger, B., Naramura, M., Kile, B. T. & Lau, N. C., 20 Nov 2015, In : PLoS Genetics. 11, 11, 26 p., e1005652.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Correction: The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation (Proceedings of the National Academy of Sciences of the United States of America (1999) 96, 5 (2071-2076) DOI: 10.1073/pnas.96.5.2071)

Zhang, J. G., Farley, A., Nicholson, S. E., Willson, T. A., Zugaro, L. M., Simpson, R. J., Moritz, R. L., Cary, D., Richardson, R., Hausmann, G., Kile, B. T., Kent, S. B. H., Alexander, W. S., Metcalf, D., Hilton, D. J., Nicola, N. A. & Baca, M., 2 Jun 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 22, p. E2979

Research output: Contribution to journalComment / DebateOtherpeer-review

12 Citations (Scopus)

Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis

Cottle, D. L., Ursino, G. M. A., Ip, S. C. L., Jones, L. K., Ditommaso, T. M., Hacking, D. F., Mangan, N. E., Mellett, N. A., Henley, K. J., Sviridov, D., Nold-Petry, C. A., Nold, M. F., Meikle, P. J., Kile, B. T. & Smyth, I. M., 2015, In : Human Molecular Genetics. 24, 2, p. 436-449 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Mice Haploinsufficient for Ets1 and Fli1 display middle ear abnormalities and model aspects of Jacobsen syndrome

Carpinelli, M. R., Kruse, E. A., Arhatari, B. D., Debrincat, M. A., Ogier, J. M., Bories, J-C., Kile, B. T. & Burt, R. A., Jul 2015, In : American Journal of Pathology. 185, 7, p. 1867-1876 10 p., 2047.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments

Schevzov, G., Kee, A. J., Wang, B., Sequeira, V. B., Hook, J., Coombes, J. D., Lucas, C. A., Stehn, J. R., Musgrove, E. A., Cretu, A., Assoiane, R., Fath, T., Hanoch, T., Seger, R., Pleines, I., Kile, B. T., Hardeman, E. C. & Gunning, P. W., 1 Jul 2015, In : Molecular Biology of the Cell. 26, 13, p. 2475-2490 16 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

SOCS4 is dispensable for an efficient recall response to influenza despite being required for primary immunity

Kedzierski, L., Clemens, E. B., Bird, N. L., Kile, B. T., Belz, G. T., Nicola, N. A., Kedzierska, K. & Nicholson, S. E., Nov 2015, In : Immunology and Cell Biology. 93, 10, p. 909-913 5 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Stressed mitochondria sound the alarm

White, M. J. & Kile, B. T., 28 May 2015, In : Immunology and Cell Biology. 93, 5, p. 427-428 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

2014
23 Citations (Scopus)

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

Potts, K. S., Sargeant, T. J., Markham, J. F., Shi, W., Biben, C., Josefsson, E. C., Whitehead, L. W., Rogers, K. L., Liakhovitskaia, A., Smyth, G. K., Kile, B. T., Medvinsky, A., Alexander, W. S., Hilton, D. J. & Taoudi, S., 23 Oct 2014, In : Blood. 124, 17, p. 2725-2729 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

A new mouse model of Canavan leukodystrophy displays hearing impairment due to central nervous system dysmyelination

Carpinelli, M. R., Voss, A. K., Manning, M. G., Perera, A. A., Cooray, A. A., Kile, B. T. & Burt, R. A., 2014, In : Disease Models and Mechanisms. 7, 6, p. 649-657 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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248 Citations (Scopus)

Apoptotic caspases suppress mtDNA-induced STING-mediated type i IFN production

White, M. J., McArthur, K., Metcalf, D., Lane, R. M., Cambier, J. C., Herold, M. J., van Delft, M. F., Bedoui, S., Lessene, G., Ritchie, M. E., Huang, D. C. S. & Kile, B. T., 18 Dec 2014, In : Cell. 159, 7, p. 1549-1562 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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12 Citations (Scopus)

CHD7 deficiency in " Looper", a new mouse model of CHARGE syndrome, results in ossicle malformation, otosclerosis and hearing impairment

Ogier, J. M., Carpinelli, M., Arhatari, B. D., Symons, RC. A., Kile, B. T. & Burt, R. A., 2014, In : PLoS ONE. 9, 5, 11 p., e97559.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

Effect of thrombopoietin receptor agonists on the apoptotic profile of platelets in patients with chronic immune thrombocytopenia

Mitchell, W. B., Pinheiro, M. P., Boulad, N., Kaplan, D., Edison, M. N., Psaila, B., Karpoff, M., White, M. J., Josefsson, E. C., Kile, B. T. & Bussel, J. B., Dec 2014, In : American Journal of Hematology. 89, 12, p. E228-E234 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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32 Citations (Scopus)

Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan

Liu, Z-J., Hoffmeister, K. M., Hu, Z., Mager, D. E., Ait-Oudhia, S., Debrincat, M. A., Pleines, I., Josefsson, E. C., Kile, B. T., Italiano Jr, J., Ramsey, H., Grozovsky, R., Veng-Pedersen, P., Chavda, C. & Sola-Visner, M., 29 May 2014, In : Blood. 123, 22, p. 3381-3389 9 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Loss of Bak enhances lymphocytosis but does not ameliorate thrombocytopaenia in BCL-2 transgenic mice

Vandenberg, CJ., Josefsson, EC., Campbell, KJ., James, C., Lawlor, KE., Kile, BT. & Cory, S., Jan 2014, In : Cell Death and Differentiation. 21, 5, p. 676-684 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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104 Citations (Scopus)

Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming

Allam, R., Lawlor, K. E., Yu, E. C-W., Mildenhall, A. L., Moujalled, D. M., Lewis, R. S., Ke, F., Mason, K. D., White, M. J., Stacey, K. J., Strasser, A., O'Reilly, L., Alexander, W., Kile, B. T., Vaux, D. L. & Vince, J. E., 1 Sep 2014, In : EMBO Reports. 15, 9, p. 982-990 9 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

NLRP1a expression in srebp-1a-deficient mice

Gerlic, M., Croker, B. A., Cengia, L. H., Moayeri, M., Kile, B. T. & Masters, S. L., 4 Mar 2014, In : Cell Metabolism. 19, 3, p. 345-346 2 p.

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