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Personal profile

Biography

I am a research scientist who studies the DNA of bacteria using computational biology, then tests hypotheses in the laboratory using micro and molecular biology.

I am currently working as a postdoctoral research fellow with Dr. Kelly Wyres within the Infectious Diseases Genomics @ Alfed, within the Department of Infectious Diseases, Central Clinical School at Monash University (2020 - current). I use genomic and bioinformatic techniques to look at the evolutionary history of Klebsiella pneumoniae, a notable infectious pathogen. I study the metabolism of these pathogens via metabolic modelling and comparative genomics. 

Prior to this, I completed a 1.5 year postdoctoral position at the Griffith Institute of Drug Discovery, Griffith University (2018 - 2019). I used structural biology and computational approaches to inform wet-lab experiments to study the circular bacteriocin, plantacyclin B21AG.

I have also worked as a research scientist at RMIT university doing diagnostics, RNA sequencing analysis and genomics of chicken pathogen Campylobacter hepaticus, the cause of spotty liver disease (2018). 

I completed a PhD in molecular and microbiology at the Biomedicine Discovery Institute, Monash University (2014 - 2018), where I worked on constructing a live vaccine for chickens, using the commensal bacteria Ligilactobacillus agilis. I discovered new constitutive promoters which I then used as genetic tools and novel expression systems.

I completed Honours at Deakin University (2013) where I constructed novel shuttle plasmids for commensal bacteria Ligilactobacillus agilis using native plasmids as a backbone.

Research interests

I am concerned about antibiotic resistance and am focused on alternative approaches to combat this serious issue, such as developing vaccines, antimicrobial proteins, diagnostics and surveillance, all of which are informed by genetics-based approaches. Also, bacteria are just cool, so that makes them interesting and worthy of study in their own right.

Feel free to check out my Scholar and ORCID pages to see my written contributions to science 

 

Consulting

Outside of direct academic collaborations, I do bioinformatics consulting for biotech companies and research groups. Please feel free to get in touch if you have sequencing data and would like analysis performed. 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Molecular and Microbiology, PhD, Development of Lactobacillus agilis La3 as a live vector for the delivery of vaccine antigens to the gastrointestinal tract of chickens

1 Feb 20141 May 2018

Award Date: 1 Aug 2018

External positions

Freelance Computational Biology

1 Apr 20201 Oct 2020

Postdoctoral Research Fellow, Griffith University

11 Jan 201915 Apr 2020

Research Scientist, RMIT University

1 Jan 20181 Sept 2018

Research area keywords

  • Computational Biology
  • Bioinformatics
  • Molecular Biology
  • Microbiology
  • Antimicrobial Resistance
  • Antimicrobial agent
  • Vaccine design
  • Genomics
  • Genetics, microbial

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or