Projects per year
Personal profile
Biography
Ben is a neuroscientist with a background in physics. He has worked in astrophysics, characterizing the magnetic field of Saturn and the matter/energy makeup of the universe, and in particle physics at CERN, researching the theory of supersymmetry. His current research is split into two areas. The first is using physical exercise as a treatment for brain diseases. After finding that an unsupervised moderate intensity exercise regime did little to help patients at risk of Alzheimer’s Disease, he is now looking at more vigorous and assisted exercise treatments, teaming up with the Isodynamics Company to test their Reviver device. The second avenue of research is using artificial intelligence in brain imaging. After finding that success in epilepsy surgery is associated with PET image characteristics, he is now using these images in AI algorithms to see whether we can use these characteristics to decide who we should send to surgery.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Brain Imaging
- Epilepsy
- Parkinson's disease
- fMRI
Collaborations and top research areas from the last five years
Projects
- 1 Finished
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REVIVER: The Assessment of a Novel Form of Exercise on Parkinsonism
Sinclair, B. (Primary Chief Investigator (PCI)), O'Brien, T. (Supervisor), Bertram, K. (Associate Investigator (AI)), Fielding, J. (Associate Investigator (AI)), Clough, M. (Associate Investigator (AI)) & White, O. (Associate Investigator (AI))
15/12/18 → 29/07/21
Project: Research
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Metabolic patterns and seizure outcomes following anterior temporal lobectomy
Cahill, V., Sinclair, B., Malpas, C. B., McIntosh, A. M., Chen, Z., Vivash, L. E., O'Shea, M. F., Wilson, S. J., Desmond, P. M., Berlangieri, S. U., Hicks, R. J., Rowe, C. C., Morokoff, A. P., King, J. A., Fabinyi, G. C., Kaye, A. H., Kwan, P., Berkovic, S. F. & O'Brien, T. J., 1 Feb 2019, In: Annals of Neurology. 85, 2, p. 241-250 10 p.Research output: Contribution to journal › Article › Research › peer-review
32 Citations (Scopus) -
Amygdala enlargement in temporal lobe epilepsy: Histopathology and surgical outcomes
Shakhatreh, L. (Leading Author), Sinclair, B., McLean, C., Lui, E., Morokoff, A. P., King, J. A., Chen, Z., Perucca, P., O'Brien, T. J. & Kwan, P. (Leading Author), Jun 2024, In: Epilepsia. 65, 6, p. 1709-1719 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Association of Localizing 18F-FDG-PET Hypometabolism and Outcome Following Epilepsy Surgery: Systematic Review and Meta-Analysis
Courtney, M. R., Antonic-Baker, A., Chen, Z., Sinclair, B., Nicolo, J. P., Neal, A., Marotta, C., Bunyamin, J., Law, M., Kwan, P., O'Brien, T. J. & Vivash, L. (Leading Author), 14 May 2024, In: Neurology. 102, 9, 14 p., e209304.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
Automated segmentation of epilepsy surgical resection cavities: Comparison of four methods to manual segmentation
Courtney, M. R., Sinclair, B., Neal, A., Nicolo, J. P., Kwan, P., Law, M., O'Brien, T. J. & Vivash, L. (Leading Author), 1 Aug 2024, In: NeuroImage. 296, 8 p., 120682.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Combining OPM and lesion mapping data for epilepsy surgery planning: a simulation study
Mellor, S., Timms, R. C., O’Neill, G. C., Tierney, T. M., Spedden, M. E., Brookes, M. J., Wagstyl, K., Barnes, G. R. & The MELD Project Consortium, Dec 2024, In: Scientific Reports. 14, 1, 12 p., 2882.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus)