Projects per year
Personal profile
Biography
Ben is a neuroscientist with a background in physics. He has worked in astrophysics, characterizing the magnetic field of Saturn and the matter/energy makeup of the universe, and in particle physics at CERN, researching the theory of supersymmetry. His current research is split into two areas. The first is using physical exercise as a treatment for brain diseases. After finding that an unsupervised moderate intensity exercise regime did little to help patients at risk of Alzheimer’s Disease, he is now looking at more vigorous and assisted exercise treatments, teaming up with the Isodynamics Company to test their Reviver device. The second avenue of research is using artificial intelligence in brain imaging. After finding that success in epilepsy surgery is associated with PET image characteristics, he is now using these images in AI algorithms to see whether we can use these characteristics to decide who we should send to surgery.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Brain Imaging
- Epilepsy
- Parkinson's disease
- fMRI
Collaborations and top research areas from the last five years
Projects
- 1 Finished
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REVIVER: The Assessment of a Novel Form of Exercise on Parkinsonism
Sinclair, B., O'Brien, T., Bertram, K., Fielding, J., Clough, M. & White, O.
15/12/18 → 29/07/21
Project: Research
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Metabolic patterns and seizure outcomes following anterior temporal lobectomy
Cahill, V., Sinclair, B., Malpas, C. B., McIntosh, A. M., Chen, Z., Vivash, L. E., O'Shea, M. F., Wilson, S. J., Desmond, P. M., Berlangieri, S. U., Hicks, R. J., Rowe, C. C., Morokoff, A. P., King, J. A., Fabinyi, G. C., Kaye, A. H., Kwan, P., Berkovic, S. F. & O'Brien, T. J., 1 Feb 2019, In: Annals of Neurology. 85, 2, p. 241-250 10 p.Research output: Contribution to journal › Article › Research › peer-review
22 Citations (Scopus) -
Associations of Enlarged Perivascular Spaces With Brain Lesions, Brain Age, and Clinical Outcomes in Chronic Traumatic Brain Injury
Hicks, A. J., Sinclair, B., Shultz, S. R., Pham, W., Silbert, L. C., Schwartz, D. L., Rowe, C. C., Ponsford, J. L., Law, M. & Spitz, G., 4 Jul 2023, In: Neurology. 101, 1, p. e63-e73 10 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Automated Methods for Detecting and Quantitation of Enlarged Perivascular spaces on MRI
Moses, J., Sinclair, B., Law, M., O'Brien, T. J. & Vivash, L., Jan 2023, In: Journal of Magnetic Resonance Imaging. 57, 1, p. 11-24 14 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access5 Citations (Scopus) -
18F-FDG-PET hypometabolism as a predictor of favourable outcome in epilepsy surgery: protocol for a systematic review and meta-analysis
Courtney, M. R., Antonic-Baker, A., Sinclair, B., Nicolo, J. P., Neal, A., Law, M., Kwan, P., O'Brien, T. J. & Vivash, L., 6 Oct 2022, In: BMJ Open. 12, 10, 5 p., e065440.Research output: Contribution to journal › Article › Other › peer-review
Open Access -
A critical guide to the automated quantification of perivascular spaces in magnetic resonance imaging
Pham, W., Lynch, M., Spitz, G., O’Brien, T., Vivash, L., Sinclair, B. & Law, M., 14 Dec 2022, In: Frontiers in Neuroscience. 16, 27 p., 1021311.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access1 Citation (Scopus)