Personal profile
Biography
Ashleigh Rogers is an ECR working at the Biomedicine Discovery Institute, Monash University. She completed her PhD in Clinical Microbiology at Monash University in 2024, under the supervision of Dr. Steven Mileto, Prof. Helen Abud, and Prof. Dena Lyras. Her studies focused on how the colon repairs following Clostridioides difficile infection (CDI)-mediated damage. Her work established and validated a novel CDI recovery mouse model and identified key timelines in the return of crucial intestinal integrity mechanisms, as well as, the impairment and activation of different regenerative mechanisms throughout CDI. Currently, Ash is working as an ECR in Prof. Dena Lyras' lab at Monash University, examining how bacterial pathogens respond and adapt to highly dynamic environments, namely a repairing colon.
Education/Academic qualification
Microbiology, Doctorate of Philosophy, Understanding host colonic recovery following Clostridioides difficile infection, MONASH UNIVERSITY
7 Oct 2019 → 7 Feb 2024
Award Date: 7 Feb 2024
Research area keywords
- Clostridium difficile
- host-pathogen interactions
- Regeneration
- colonic repair
- Clostridia
- Clostridial toxins
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Impact of enteric bacterial infections at and beyond the epithelial barrier
Rogers, A. P., Mileto, S. J. & Lyras, D., Apr 2023, In: Nature Reviews Microbiology. 21, 4, p. 260-274 15 p.Research output: Contribution to journal › Review Article › Research › peer-review
93 Link opens in a new tab Citations (Scopus) -
Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease
Mileto, S. J., Jardé, T., Childress, K. O., Jensen, J. L., Rogers, A. P., Kerr, G., Hutton, M. L., Sheedlo, M. J., Bloch, S. C., Shupe, J. A., Horvay, K., Flores, T., Engel, R., Wilkins, S., McMurrick, P. J., Lacy, D. B., Abud, H. E. & Lyras, D., 7 Apr 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 14, p. 8064-8073 10 p.Research output: Contribution to journal › Article › Research › peer-review
84 Link opens in a new tab Citations (Scopus)