20062023
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Research Output 2006 2019

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2019

Prognostic Utility of a Whole-blood Androgen Receptor-based Gene Signature in Metastatic Castration-resistant Prostate Cancer

Kwan, E. M., Fettke, H., Docanto, M. M., To, S. Q., Bukczynska, P., Mant, A., Pook, D., Ng, N., Graham, L. J. K., Mangiola, S., Segelov, E., Mahon, K., Davis, I. D., Parente, P., Pezaro, C., Todenhöfer, T., Horvath, L. G. & Azad, A. A., 15 May 2019, (Accepted/In press) In : European Urology Focus. 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

A prognostic model for stratifying clinical outcomes in chemotherapy-naive metastatic castration-resistant prostate cancer patients treated with abiraterone acetate

Khalaf, D. J., Avilés, C. M., Azad, A. A., Sunderland, K., Todenhöfer, T., Eigl, B. J., Finch, D., Le, L., Atwell, A., Keith, B., Kollmannsberger, C. & Chi, K. N., 1 Feb 2018, In : Canadian Urological Association. 12, 2, p. E47-E52 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Circulating tumor DNA genomics correlate with resistance to abiraterone and enzalutamide in prostate cancer

Annala, M., Vandekerkhove, G., Khalaf, D., Taavitsainen, S., Beja, K., Warner, E. W., Sunderland, K., Kollmannsberger, C., Eigl, B. J., Finch, D., Oja, C. D., Vergidis, J., Zulfiqar, M., Azad, A. A., Nykter, M., Gleave, M. E., Wyatt, A. W. & Chi, K. N., 1 Apr 2018, In : Cancer Discovery. 8, 4, p. 444-457 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Expression of Androgen Receptor Splice Variant 7 or 9 in Whole Blood Does Not Predict Response to Androgen-Axis–targeting Agents in Metastatic Castration-resistant Prostate Cancer

To, S. Q., Kwan, E. M., Fettke, H. C., Mant, A., Docanto, M. M., Martelotto, L., Bukczynska, P., Ng, N., Graham, L. J. K., Parente, P., Pezaro, C., Mahon, K., Horvath, L., Todenhöfer, T. & Azad, A. A., 1 Jun 2018, In : European Urology. 73, 6, p. 818-821 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

Lawrence, M. G., Obinata, D., Sandhu, S., Selth, L. A., Wong, S. Q., Porter, L. H., Lister, N., Pook, D., Pezaro, C. J., Goode, D. L., Rebello, R. J., Clark, A. K., Papargiris, M., Van Gramberg, J., Hanson, A. R., Banks, P., Wang, H., Niranjan, B., Keerthikumar, S., Hedwards, S. & 32 others, Huglo, A., Yang, R., Henzler, C., Li, Y., Lopez-Campos, F., Castro, E., Toivanen, R., Azad, A., Bolton, D., Goad, J., Grummet, J., Harewood, L., Kourambas, J., Lawrentschuk, N., Moon, D., Murphy, D. G., Sengupta, S., Snow, R., Thorne, H., Mitchell, C., Pedersen, J., Clouston, D., Norden, S., Ryan, A., Dehm, S. M., Tilley, W. D., Pearson, R. B., Hannan, R. D., Frydenberg, M., Furic, L., Taylor, R. A. & Risbridger, G. P., 1 Nov 2018, In : European Urology. 74, 5, p. 562-572 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Safety of pazopanib and sunitinib in treatment-naive patients with metastatic renal cell carcinoma: Asian versus non-Asian subgroup analysis of the COMPARZ trial

Guo, J., Jin, J., Oya, M., Uemura, H., Takahashi, S., Tatsugami, K., Rha, S. Y., Lee, J. L., Chung, J., Lim, H. Y., Wu, H. C., Chang, Y. H., Azad, A., Davis, I. D., Carrasco-Alfonso, M. J., Nanua, B., Han, J., Ahmad, Q. & Motzer, R., 22 May 2018, In : Journal of Hematology & Oncology. 11, 1, 10 p., 69.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2017

AR-V7 Transcripts in Whole Blood RNA of Patients with Metastatic Castration Resistant Prostate Cancer Correlate with Response to Abiraterone Acetate

Todenhöfer, T., Azad, A., Stewart, C., Gao, J., Eigl, B. J., Gleave, M. E., Joshua, A. M., Black, P. C. & Chi, K. N., 1 Jan 2017, In : Journal of Urology. 197, 1, p. 135-142 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular dissection of complete response to receptor tyrosine kinase inhibition in type II papillary renal cell carcinoma

Annala, M., Nappi, L., Azad, A. A., Mo, F., Fazli, L., Chi, K. N. & Wyatt, A. W., Feb 2017, In : Clinical Genitourinary Cancer. 15, 1, p. e145-e150 6 p.

Research output: Contribution to journalArticleOtherpeer-review

2016

A prognostic index model for predicting overall survival in patients with metastatic castration-resistant prostate cancer treated with abiraterone acetate after docetaxel

Chi, K. N., Kheoh, T., Ryan, C. J., Molina, A., Bellmunt, J., Vogelzang, N. J., Rathkopf, D. E., Fizazi, K., Kantoff, P. W., Li, J., Azad, A. A., Eigl, B. J., Heng, D. Y. C., Joshua, A. M., De Bono, J. S. & Scher, H. I., 2016, In : Annals of Oncology. 27, 3, p. 454-460 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Benefit from cytoreductive nephrectomy and the prognostic role of neutrophil-to-lymphocyte ratio in patients with metastatic renal cell carcinoma

Day, D., Kanjanapan, Y., Kwan, E., Yip, D., Lawrentschuk, N., Davis, I. D., Azad, A. A., Wong, S., Rosenthal, M., Gibbs, P. & Tran, B., 1 Nov 2016, In : Internal Medicine Journal. 46, 11, p. 1291-1297 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Changes in plasma biomarkers following treatment with cabozantinib in metastatic castration-resistant prostate cancer: a post hoc analysis of an extension cohort of a phase II trial

Leibowitz-Amit, R., Pintilie, M., Khoja, L., Azad, A. A., Berger, R., Laird, A. D., Aftab, D. T., Chi, K. N. & Cardin, A. J., 13 Jan 2016, In : Journal of Translational Medicine. 14, 1, 8 p., 12.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Continuous flow deformability-based separation of circulating tumor cells using microfluidic ratchets

Park, E. S., Jin, C., Guo, Q., Ang, R. R., Duffy, S. P., Matthews, K., Azad, A., Abdi, H., Todenhofer, T., Bazov, J., Chi, K. N., Black, P. C. & Ma, H., 13 Apr 2016, In : Small. 12, 14, p. 1909-1919 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Functional analysis of androgen receptor mutations that confer anti-androgen resistance identified in circulating cell-free DNA from prostate cancer patients

Lallous, N., Volik, S. V., Awrey, S., Leblanc, E., Tse, R., Murillo, J., Singh, K., Azad, A. A., Wyatt, A. W., LeBihan, S., Chi, K. N., Gleave, M. E., Rennie, P. S., Collins, C. C. & Cherkasov, A., 26 Jan 2016, In : Genome Biology. 17, 15 p., 10.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Genomic alterations in cell-free DNA and enzalutamide resistance in castration-resistant prostate cancer

Wyatt, A. W., Azad, A., Volik, S., Annala, M., Beja, K., McConeghy, B. J., Haegert, A., Warner, E. W., Mo, F., Brahmbhatt, S., Shukin, R., LeBihan, S., Gleave, M. E., Nykter, M., Collins, C. C. & Chi, K. N., 1 Dec 2016, In : JAMA Oncology. 2, 12, p. 1598-1606 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Integrated analysis of the prostate cancer small-nucleolar transcriptome reveals SNORA55 as a driver of prostate cancer progression

Crea, F., Quagliata, L., Michael, A., Liu, H. H. R., Frumento, P., Azad, A. A., Xue, H., Pikor, L. A., Watahiki, A., Morant, R., Eppenberger-Castori, S., Wang, Y., Parolia, A., Lennox, K. A., Lam, W. L., Gleave, M. E., Chi, K. N., Pandha, H. S., Wang, Y. & Helgason, C. D., May 2016, In : Molecular Oncology. 10, 5, p. 693-703 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2015

Activity of enzalutamide in men with metastatic castration-resistant prostate cancer is affected by prior treatment with abiraterone and/or docetaxel

Cheng, H. H., Gulati, R., Azad, A., Nadal, R., Twardowski, P., Vaishampayan, U. N., Agarwal, N., Heath, E., Pal, S., Rehman, H., Leiter, A., Batten, J., Montgomery, R. B., Galsky, M. D., Antonarakis, E. S., Chi, K. N. & Yu, E., 2015, In : Prostate Cancer and Prostatic Diseases. 18, 2, p. 122-127 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Androgen receptor gene aberrations in circulating cell-free DNA: Biomarkers of therapeutic resistance in castration-resistant prostate cancer

Azad, A. A., Volik, S., Wyatt, A. W., Haegert, A., LeBihan, S., Bell, R. H., Anderson, S., McConeghy, B. J., Shukin, R., Bazov, J., Youngren, J., Paris, P. L., Thomas, G., Small, E. J., Wang, Y., Gleave, M. E., Collins, C. C. & Chi, K. N., 2015, In : Clinical Cancer Research. 21, 10, p. 2315-2324 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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A Phase I/II Trial of BNC105P with Everolimus in Metastatic Renal Cell Carcinoma

Pal, S., Azad, A., Bhatia, S., Drabkin, H. A., Costello, B. J., Sarantopoulos, J., Kanesvaran, R., Lauer, R., Starodub, A., Hauke, R., Sweeney, C. J., Hahn, N., Sonpavde, G., Richey, S., Breen, T., Kremmidiotis, G., Leske, A. F., Doolin, E., Bibby, D., Iglesias, J. & 1 others, Hutson, T. E., 2015, In : Clinical Cancer Research. 21, 15, p. 3420-3427 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Efficacy of enzalutamide following abiraterone acetate in chemotherapy-naive metastatic castration-resistant prostate cancer patients

Azad, A. A., Eigl, B. J., Murray, R. N., Kollmannsberger, C. & Chi, K. N., 2015, In : European Urology. 67, 1, p. 23-29 7 p.

Research output: Contribution to journalArticleResearchpeer-review

EVERSUN: a phase 2 trial of alternating sunitinib and everolimus as first-line therapy for advanced renal cell carcinoma

Davis, I., Long, A., Yip, S., Espinoza, D., Thompson, J. F., Kichenadsasse, G., Harrison, M., Lowenthal, R. M., Pavlakis, N., Azad, A., Kannourakis, G., Steer, C., Goldstein, D. A., Shapiro, J., Harvie, R. M., Jovanovic, L., Hudson, A. L., Nelson, C. C., Stockler, M. R. & Martin, A. V., 2015, In : Annals of Oncology. 26, 6, p. 1118 - 1123 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Lymphadenectomy with radical cystectomy at an Australian tertiary referral institution: time trends and impact on oncological outcomes

Eapen, R., Liew, M. S., Tafreshi, A., Papa, N., Lawrentschuk, N., Azad, A., Davis, I., Bolton, D. M. & Sengupta, S., 2015, In : ANZ Journal of Surgery. 85, 7-8, p. 535-539 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Outcomes with abiraterone acetate in metastatic castration-resistant prostate cancer patients who have poor performance status

Azad, A. A., Eigl, B. J. C., Leibowitz-Amit, R., Lester, R., Kollmannsberger, C., Murray, R. N., Clayton, R., Heng, D., Joshua, A. M. & Chi, K. N., 2015, In : European Urology. 67, 3, p. 441-447 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Patterns of care for metastatic renal cell carcinoma in Australia

Day, D., Kanjanapan, Y., Kwan, E., Yip, D., Lawrentschuk, N., Andrews, M. C., Davis, I., Azad, A., Rosenthal, M. A., Wong, S., Johnstone, A. L., Gibbs, P. & Tran, B., 2015, In : BJU International. 116, p. 36 - 41 6 p.

Research output: Contribution to journalArticleResearchpeer-review

PD-L1 is highly expressed in Enzalutamide resistant prostate cancer

Bishop, J. L., Sio, A., Angeles, A., Roberts, M. E., Azad, A. A., Chi, K. N. & Zoubeidi, A., 2015, In : Oncotarget. 6, 1, p. 234-242 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Size and deformability based separation of circulating tumor cells from castrate resistant prostate cancer patients using resettable cell traps

Park, E. S., Duffy, S. P., Matthews, K., Ang, R. R., Todenhofer, T., Abdi, H., Azad, A., Bazov, J., Chi, K. N., Black, P. C. & Ma, H., 2015, In : Lab on a Chip. 15, 10, p. 2278-2286 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Targeting heat shock proteins in metastatic castration-resistant prostate cancer

Azad, A. A., Zoubeidi, A., Gleave, M. E. & Chi, K. N., 2015, In : Nature Reviews Urology. 12, 1, p. 26-36 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2014

A randomized phase II efficacy and safety study of vandetanib (ZD6474) in combination with bicalutamide versus bicalutamide alone in patients with chemotherapy naive castration-resistant prostate cancer

Azad, A. A., Beardsley, E. K., Hotte, S. J., Ellard, S. L., Klotz, L., Chin, J., Kollmannsberger, C., Mukherjee, S. D. & Chi, K. N., Aug 2014, In : Investigational New Drugs. 32, 4, p. 746-752 7 p.

Research output: Contribution to journalArticleResearchpeer-review

A retrospective, Canadian multi-center study examining the impact of prior response to abiraterone acetate on efficacy of docetaxel in metastatic castration-resistant prostate cancer

Azad, A. A., Leibowitz-Amit, R., Eigl, B. J. C., Lester, R., Wells, J. C., Murray, R. N., Kollmannsberger, C., Heng, D. YC., Joshua, A. M. & Chi, K. N., Nov 2014, In : Prostate. 74, 15, p. 1544-1550 7 p.

Research output: Contribution to journalArticleResearchpeer-review

A single-centre experience of patients with metastatic melanoma enrolled in a dabrafenib named patient programme

Lau, D. K., Andrews, M. C., Turner, N., Azad, A., Davis, I. & Cebon, J., 2014, In : Melanoma Research. 24, 2, p. 144 - 149 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Co-targeting deoxyribonucleic acid-dependent protein kinase and poly(adenosine diphosphate-ribose) polymerase-1 promotes accelerated senescence of irradiated cancer cells

Azad, A., Bukczynska, P. E., Jackson, S., Haupt, Y., Cullinane, C. M., McArthur, G. A. & Solomon, B. J., Feb 2014, In : International Journal of Radiation Oncology Biology Physics. 88, 2, p. 385-394 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Discharge patterns, survival outcomes, and changes in clinical management of hospitalized adult patients with cancer with a do-not-resuscitate order

Azad, A., Siow, S-F., Tafreshi, A., Moran, J. & Franco, M., 2014, In : Journal of Palliative Medicine. 17, 7, p. 776 - 781 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Metastatic large-cell neuroendocrine prostate carcinoma: Successful treatment with androgen deprivation therapy

Azad, A. A., Jones, E. C. & Chi, K. N., 2014, In : Clinical Genitourinary Cancer. 12, 4, 3 p.

Research output: Contribution to journalArticleOtherpeer-review

Population-based impact on overall survival after the introduction of docetaxel as standard therapy for metastatic castration resistant prostate cancer

Zielinski, R. R., Azad, A., Chi, K. N. & Tyldesely, S., 2014, In : Canadian Urological Association Journal. 8, 7-8, p. 520-523 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Prostate cancer - double vision but solitary lesion

Lim, H. Y., Perchyonok, Y., Fitt, G., Lokan, J., Wada, M., Fabinyi, G., Azad, A., Cher, L. & Gan, H. K., 30 Apr 2014, In : Journal of Case Reports and Studies. 2, 2, 3 p., 201.

Research output: Contribution to journalArticleOther

Open Access
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Two decades in review: Progress in the treatment of mCRPC

Bernard, B., Azad, A. A. & Chi, K. N., 1 Aug 2014, In : Oncology Exchange. 13, 3, p. 18-23 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Uro-oncology multidisciplinary meetings at an Australian tertiary referral centre--impact on clinical decision-making and implications for patient inclusion

Rao, K., Manya, K., Azad, A., Lawrentschuk, N., Bolton, D. M., Davis, I. & Sengupta, S., 2014, In : BJU International. 114, S1, p. 50 - 54 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Radiation recall dermatitis induced by pazopanib

Azad, A., Maddison, C. & Stewart, J., Nov 2013, In : Onkologie. 36, 11, p. 674-676 3 p.

Research output: Contribution to journalArticleOtherpeer-review

Sonolisib: Pan-phosphatidylinositol 3-kinase (PI3K) inhibitor, Oncolytic

Azad, A. & Chi, K. N., 2013, In : Drugs of the Future. 38, 5, p. 299 - 308 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The Role of Cancer-Testis Antigens as Predictive and Prognostic Markers in Non-Small Cell Lung Cancer

John, T., Starmans, M. H. W., Chen, Y-T., Russell, P. A., Barnett, S. A., White, S. C., Mitchell, P., Walkiewicz, M., Azad, A., Lambin, P., Tsao, M-S., Deb, S., Altorki, N. K., Wright, G. M., Knight, S., Boutros, P. C. & Cebon, J., 2013, In : PLoS ONE. 8, 7, p. 1 - 8 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

USANZ: Time-trends in use and impact on outcomes of perioperative chemotherapy in patients treated with radical cystectomy for urothelial bladder cancer

Liew, M. S., Azad, A., Tafreshi, A., Eapen, R., Bolton, D., Davis, I. & Sengupta, S., 2013, In : BJU International. 112, Suppl 2, p. 74 - 82 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy-refractory, advanced colorectal cancer

Weickhardt, A. J., Price, T. J., Chong, G., Gebski, V., Pavlakis, N., Johns, T. G., Azad, A., Skrinos, E., Fluck, K., Dobrovic, A., Salemi, R., Scott, A. M., Mariadason, J. M. & Tebbutt, N. C., 2012, In : Journal of Clinical Oncology. 30, 13, p. 1505 - 1512 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Cancer-Testis antigen expression in primary cutaneous melanoma has independent prognostic value comparable to that of Breslow thickness, ulceration and mitotic rate.

Svobodova, S., Browning, J., McGregor, D., Pollara, G., Scolyer, R., Murali, R., Thompson, J., Deb, S., Azad, A., Davis, I. & Cebon, J., 2011, In : European Journal of Cancer. 47, 3, p. 460 - 469 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Inhibition of DNA-dependent protein kinase induces accelerated senescence in irradiated human cancer cells

Azad, A., Jackson, S., Cullinane, C. M., Natoli, A. L., Neilsen, P. M., Callen, D. F., Maira, S-M., Hackl, W., McArthur, G. A. & Solomon, B. J., 2011, In : Molecular Cancer Research. 9, 12, p. 1696 - 1707 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2010

18F-FDG-PET imaging of a benign neurofibroma masquerading as metastatic oesophageal carcinoma

Azad, A., Chong, G., Tauro, A., Aly, A. & Tebbutt, N. C., Jun 2010, In : Medical Oncology. 27, 2, p. 230-232 3 p.

Research output: Contribution to journalArticleResearchpeer-review

High impact of 18F-FDG-PET on management and prognostic stratification of newly diagnosed small cell lung cancer.

Azad, A., Chionh, F., Scott, A. M., Lee, S. T., Berlangieri, S. U., White, S. & Mitchell, P. L., Aug 2010, In : Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 12, 4, p. 443-451 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Neurolymphomatosis: Diagnosis, management, and outcomes in patients treated with rituximab

Gan, H. K., Azad, A., Cher, L. & Mitchell, P. L. R., Feb 2010, In : Neuro-Oncology. 12, 2, p. 212-215 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Dexamethasone-induced flares of Trichophyton rubrum masquerading as docetaxel cutaneous toxicity: A case report

Azad, A., Kaufman, M. & Jayarajan, J., 2009, In : Cases Journal. 2, 7, 8552.

Research output: Contribution to journalArticleResearchpeer-review

Primary anaplastic pilocytic astrocytoma

Azad, A., Deb, S. & Cher, L., Dec 2009, In : Journal of Clinical Neuroscience. 16, 12, p. 1704-1706 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Severe cutaneous toxicity following treatment with radiotherapy and cetuximab: A case report

Azad, A., 2009, In : Cases Journal. 2, 1, 25.

Research output: Contribution to journalArticleResearchpeer-review

2007

Evans syndrome and primary biliary cirrhosis

Azad, A., Berera, V., Jayarajan, J. & Lim, K., Apr 2007, In : International Journal of Laboratory Hematology. 29, 2, p. 145-148 4 p.

Research output: Contribution to journalArticleResearchpeer-review