Arun Azad

Assoc Professor

20062021
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Personal profile

Biography

Dr Azad is an early-career medical oncologist and translational researcher with a special interest in genitourinary malignancies.
After completing his medical oncology training and a PhD in cell biology in Melbourne, Dr Azad moved to the British Columbia (BC) Cancer Agency and Vancouver Prostate Centre, Canada for a 2-year fellowship under the supervision of Professor Kim Chi, an internationally renowned prostate cancer researcher.
At BC Cancer Agency, Dr Azad played a major role in the development of five investigator-initiated clinical trials, was actively involved in outcomes research, and led pioneering studies centred on genomic profiling of circulating cell-free DNA in advanced prostate cancer patients developing resistance to next-generation hormonal agents. The significance of Dr Azad's work with cell-free DNA was recognized by four highly prestigious Merit Awards from the American Society of Clinical Oncology and first author publications in Clinical Cancer Research and JAMA Oncology.
 
Dr Azad has a strong academic record including 64 publications, a patent, 11 oral presentations at national and international meetings, Poster Highlights Sessions at the 2014 and 2015 ASCO Annual Meeting, 22 competitive prizes and awards and over $4.5M in competitive funding.
 
In November 2015, Dr Azad commenced appointments at Monash University and Monash Health, where he is leading a clinical and translational prostate cancer research program. His ongoing research centres on circulating biomarker analysis in advanced prostate cancer patients (supported by an NHMRC Project Grant) and the predictive utility of non-coding RNA for BET inhibition in prostate cancer (supported by a Victorian Cancer Agency Translational Research Project Grant). He is also actively involved in clinical trials and notably is the lead Australian investigator for two clinical trials in advanced prostate cancer patients. 

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Projects 2013 2021

Research Output 2006 2018

Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy

Lawrence, M. G. , Obinata, D. , Sandhu, S. , Selth, L. A. , Wong, S. Q. , Porter, L. H. , Lister, N. , Pook, D. , Pezaro, C. J. , Goode, D. L. , Rebello, R. J. , Clark, A. K. , Papargiris, M. , Van Gramberg, J. , Hanson, A. R. , Banks, P. , Wang, H. , Niranjan, B. , Keerthikumar, S. , Hedwards, S. & 32 others Huglo, A., Yang, R., Henzler, C., Li, Y., Lopez-Campos, F., Castro, E., Toivanen, R., Azad, A., Bolton, D., Goad, J., Grummet, J., Harewood, L., Kourambas, J., Lawrentschuk, N., Moon, D., Murphy, D. G., Sengupta, S., Snow, R., Thorne, H., Mitchell, C., Pedersen, J., Clouston, D., Norden, S., Ryan, A., Dehm, S. M., Tilley, W. D., Pearson, R. B., Hannan, R. D., Frydenberg, M., Furic, L., Taylor, R. A. & Risbridger, G. P. 23 Jul 2018 (Accepted/In press) In : European Urology. 11 p.

Research output: Contribution to journalArticle

AR-V7 Transcripts in Whole Blood RNA of Patients with Metastatic Castration Resistant Prostate Cancer Correlate with Response to Abiraterone Acetate

Todenhöfer, T., Azad, A., Stewart, C., Gao, J., Eigl, B. J., Gleave, M. E., Joshua, A. M., Black, P. C. & Chi, K. N. 1 Jan 2017 In : Journal of Urology. 197, 1, p. 135-142 8 p.

Research output: Contribution to journalArticle

Molecular dissection of complete response to receptor tyrosine kinase inhibition in type II papillary renal cell carcinoma

Annala, M., Nappi, L., Azad, A. A., Mo, F., Fazli, L., Chi, K. N. & Wyatt, A. W. Feb 2017 In : Clinical Genitourinary Cancer. 15, 1, p. e145-e150 6 p.

Research output: Contribution to journalArticle

A prognostic index model for predicting overall survival in patients with metastatic castration-resistant prostate cancer treated with abiraterone acetate after docetaxel

Chi, K. N., Kheoh, T. S., Ryan, C. J., Molina, A., Bellmunt, J., Vogelzang, N. J., Rathkopf, D. E., Fizazi, K., Kantoff, P. W., Li, J., Azad, A., Eigl, B. J. C., Heng, D., Joshua, A. M., De Bono, J. S. & Scher, H. I. 2016 In : Annals of Oncology. 27, 3, p. 454-460 7 p.

Research output: Contribution to journalArticle

Benefit from cytoreductive nephrectomy and the prognostic role of neutrophil-to-lymphocyte ratio in patients with metastatic renal cell carcinoma

Day, D., Kanjanapan, Y., Kwan, E., Yip, D., Lawrentschuk, N., Davis, I. D., Azad, A. A., Wong, S., Rosenthal, M., Gibbs, P. & Tran, B. 1 Nov 2016 In : Internal Medicine Journal. 46, 11, p. 1291-1297 7 p.

Research output: Contribution to journalArticle