1993 …2023
If you made any changes in Pure these will be visible here soon.

Research Output 1993 2019

1999

Qualitative and quantitative assessment of relative agonist efficacy

Christopoulos, A. & El-Fakahany, E. E., 1 Sep 1999, In : Biochemical Pharmacology. 58, 5, p. 735-748 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Regulation of acetylcholine binding by ATP at the muscarinic M1 receptor in intact CHO cells

Grant, M. K. O., Christopoulos, A. & El-Fakahany, E. E., 21 Aug 1999, In : Brain Research. 839, 1, p. 94-99 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The assessment of antagonist potency under conditions of transient response kinetics

Christopoulos, A., Parsons, A. M., Lew, M. J. & El-Fakahany, E. E., 15 Oct 1999, In : European Journal of Pharmacology. 382, 3, p. 217-227 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1998

Allosteric interactions at muscarinic cholinoceptors

Christopoulos, A., Lanzafame, A. & Mitchelson, F. J., 1998, In : Clinical and Experimental Pharmacology and Physiology. p. 185 - 194 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Assessing the distribution of parameters in models of ligand-receptor interaction: To log or not to log

Christopoulos, A., 1 Sep 1998, In : Trends in Pharmacological Sciences. 19, 9, p. 351-357 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of the subtype selectivity of the allosteric modulator, C7/ 3 - PHTH, at cloned muscarinic acetylcholine receptors

El-Fakahany, E. E., Christopoulos, A., Sorman, J. L. & Mitchelson, F. J., 1998, p. 14 - 14. 1 p.

Research output: Contribution to conferenceAbstractOther

Minireview: The generation of nitric oxide by G protein-coupled receptors

Christopoulos, A. & El-Fakahany, E. E., 27 Nov 1998, In : Life Sciences. 64, 1, p. 1-15 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor

Christopoulos, A., Pierce, T. L., Sorman, J. L. & El-Fakahany, E. E., 1 Jun 1998, In : Molecular Pharmacology. 53, 6, p. 1120-1130 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The interaction of otenzepad (AF- DX 116) with allosteric modulators and competitive antagonists at a muscarinic M2 receptor

Mitchelson, F. J., Lanzafame, A. & Christopoulos, A., 1998, p. 9 - 9. 1 p.

Research output: Contribution to conferenceAbstractOther

Use of a spreadsheet to quantitate the equilibrium binding of an allosteric modulator

Christopoulos, A. & Mitchelson, F. J., 1998, In : European Journal of Pharmacology. p. 103 - 111 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1997

A common site of action for two allosteric antagonists

Christopoulos, A., Lanzafame, A. & Mitchelson, F. J., 1997, p. 1173 - 1173. 1 p.

Research output: Contribution to conferenceAbstractOther

Application of an allosteric ternary complex model to the technique of pharmacological resultant analysis

Christopoulos, A. & Mitchelson, F., 1997, In : Journal of Pharmacy and Pharmacology. p. 781 - 786 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Interaction of ebeinone, an alkaloid from Fritellaria imperialis, at two muscarinic acetylcholine receptor subtypes

Gilani, A. H., Shaheen, F., Christopoulos, A. & Mitchelson, F., 17 Jan 1997, In : Life Sciences. 60, 8, p. 535-544 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Interaction of ebeinone, an alkaloid from Fritillaria imperialis, at two muscrinic acetylcholine receptor subtypes

Gilani, A. H., Shaheen, F., Christopoulos, A. & Mitchelson, F. J., 1997, In : Life Sciences. p. 535 - 544 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Kinetic studies of co-operativity at atrial muscarinic M2 receptors with an 'infinite dilution' procedure

Christopoulos, A., Lanzafame, A., Ziegler, A. & Mitchelson, F., 21 Mar 1997, In : Biochemical Pharmacology. 53, 6, p. 795-800 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Novel persistent activation of muscarinic M1 receptors by xanomeline

Christopoulos, A. & El-Fakahany, E. E., 3 Sep 1997, In : European Journal of Pharmacology. 334, 1, p. R3-R4 2 p.

Research output: Contribution to journalArticleOtherpeer-review

Pharmacological analysis of the mode of interaction of McN-A-343 at atrial muscarinic M2 receptors

Christopoulos, A. & Mitchelson, F., 1997, In : European Journal of Pharmacology. p. 153 - 156 4 p.

Research output: Contribution to journalArticleResearchpeer-review

The allosteric interaction of otenzepad at muscarinic acetylcholine M2 receptors in cardiac tissue

Lanzafame, A., Christopoulos, A. & Mitchelson, F. J., 1997, p. 47 - 47. 1 p.

Research output: Contribution to conferenceAbstractOther

Three allosteric modulators act at a common site, distinct from that of competitive antagonists, at muscarinic acetylcholine M2 receptors

Lanzafame, A., Christopoulos, A. & Mitchelson, F., 1 Jul 1997, In : Journal of Pharmacology and Experimental Therapeutics. 282, 1, p. 278-285 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Three all osteric modulators act at a common site, distinct from that of competitive antahonists, at muscarinic acetylcholine M2 receptors

Lanzafame, A., Christopoulos, A. & Mitchelson, F., 1997, In : Journal of Pharmacology and Experimental Therapeutics. p. 278 - 285 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1996

Interactions of agonists with an allosteric antagonist at muscarinic acetylcholine M2 receptors

Lanzafame, A., Christopoulos, A. & Mitchelson, F., 28 Nov 1996, In : European Journal of Pharmacology. 316, 1, p. 27-32 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Inverse agonism: A developing concept of drug action

Christopoulos, A. & Mitchelson, F., 1 Aug 1996, In : Australian Journal of Pharmacy. 77, 917, p. 868-871 4 p.

Research output: Contribution to journalArticleResearchpeer-review

1995

[3H]N-methylscopolamine dissociation from muscarine receptors affected by low concentrations of allosteric modulators

Christopoulos, A. & Mitchelson, F., 15 Aug 1995, In : European Journal of Pharmacology: Molecular Pharmacology. 290, 3, p. 259-262 4 p.

Research output: Contribution to journalArticleResearchpeer-review

1994

Assessment of the allosteric interactions of the bisquaternary heptane- 1,7-bis(dimethyl-3'-phthalimidopropyl)ammonium bromide at M1 and M2 muscarine receptors

Christopoulos, A. & Mitchelson, F., 1 Jan 1994, In : Molecular Pharmacology. 46, 1, p. 105-114 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1993