Arthur Christopoulos

Professor

Dean Faculty of Pharm & Pharmaceut Sci, Faculty of Pharmacy and Pharmaceutical Sciences

https://orcid.org/0000-0003-4442-3294

EmailArthur.Christopoulos@monash.edu

Research activity per year

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Personal profile

Monash teaching commitment

Lectures to second year BPharm students in the Faculty of Pharmacy and Pharmaceutical Sciences
Lectures to third year BPharmSci students in the Faculty of Pharmacy and Pharmaceutical Sciences
Supervision of Honours students in Drug Discovery Biology
Supervision of PhD students in Drug Discovery Biology

Research area keywords

Analytical Pharmacology
Allosteric Modulation
Receptor Theory
Commentary: Drug Discovery
Pharmaceutical Research
Drug Side-Effects
Psychiatric Drugs
Supervision: Molecular Pharmacology
Drug Discovery
Receptors and Signal Transduction

Network

Recent external collaboration on country level. Dive into details by clicking on the dots or

5 Active
28 Finished

Chemical-Biology Approaches to Pathway Selective Adenosine Receptor Ligands
Scammells, P. & Christopoulos, A.
1/07/19 → 30/06/22
Project: Research
Discovering novel allosteric probes of muscarinic acetylcholine receptors
Valant, C., Scammells, P. & Christopoulos, A.
3/06/19 → 2/06/22
Project: Research
Translating membrane proteins into therapeutics; from bedside to bench
Sexton, P., Christopoulos, A., Pantelis, C. & Parton, R. G.
1/01/19 → 31/12/23
Project: Research
Adenosine A1 receptor modulation: Structure, dynamics & novel pharmacological interventions
Christopoulos, A., May, L., Imlach, W., Hill, S. & Scott, D.
1/01/18 → 31/12/22
Project: Research
Collaborative Network to Define the Molecular Determinants of G Protein Coupled Receptor Clinical Efficacy
Christopoulos, A., Sexton, P. & Tobin, A. B.
1/11/16 → 31/10/21
Project: Research

296 Article
19 Review Article
13 Chapter (Book)
9 Comment / Debate
More

Development of Novel 4-Arylpyridin-2-one and 6-Arylpyrimidin-4-one Positive Allosteric Modulators of the M₁ Muscarinic Acetylcholine Receptor
Jörg, M., Khajehali, E., van der Westhuizen, E. T., C. Choy, K. H., Shackleford, D. M., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 8 Jan 2021, In : ChemMedChem. 16, 1, p. 216-233 18 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access

1 Citation (Scopus)
Acetylcholine Muscarinic M₄ Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents
Walker, L. C., Berizzi, A. E., Chen, N. A., Rueda, P., Perreau, V. M., Huckstep, K., Srisontiyakul, J., Govitrapong, P., Xiaojian, J., Lindsley, C. W., Jones, C. K., Riddy, D. M., Christopoulos, A., Langmead, C. J. & Lawrence, A. J., 28 Feb 2020, (Accepted/In press) In : Biological Psychiatry. 12 p.
Research output: Contribution to journal › Article › Research › peer-review

3 Citations (Scopus)
Activation of the GLP-1 receptor by a non-peptidic agonist
Zhao, P., Liang, Y. L., Belousoff, M. J., Deganutti, G., Fletcher, M. M., Willard, F. S., Bell, M. G., Christe, M. E., Sloop, K. W., Inoue, A., Truong, T. T., Clydesdale, L., Furness, S. G. B., Christopoulos, A., Wang, M. W., Miller, L. J., Reynolds, C. A., Danev, R., Sexton, P. M. & Wootten, D., 8 Jan 2020, In : Nature. 577, 7790, p. 432-436 5 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

30 Citations (Scopus)
Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs
Bradley, S. J., Molloy, C., Valuskova, P., Dwomoh, L., Scarpa, M., Rossi, M., Finlayson, L., Svensson, K. A., Chernet, E., Barth, V. N., Gherbi, K., Sykes, D. A., Wilson, C. A., Mistry, R., Sexton, P. M., Christopoulos, A., Mogg, A. J., Rosethorne, E. M., Sakata, S., John Challiss, R. A. & 2 others, Broad, L. M. & Tobin, A. B., 20 Feb 2020, In : Nature Chemical Biology. 16, 3, p. 240-249 10 p.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

9 Citations (Scopus)
Correction to “Evaluation of Operational Models of Agonism and Allosterism at Receptors with Multiple orthosteric Binding Sites” (Mol Pharmacol, (2020) 97, 1, (35-45) DOI: 10.1124/mol.119.118091)
Gregory, K. J., Giraldo, J., Diao, J., Christopoulos, A. & Leach, K., 1 Jan 2020, In : Molecular Pharmacology. 97, 1, p. 48-48 1 p.
Research output: Contribution to journal › Comment / Debate › Other › peer-review

1 Submissions to industry or govt committees, commissions and inquiries

Theme Leader
Arthur Christopoulos (Member)
10 Nov 2011
Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries