Projects per year
Personal profile
Monash teaching commitment
- Lectures to second year BPharm students in the Faculty of Pharmacy and Pharmaceutical Sciences
- Lectures to third year BPharmSci students in the Faculty of Pharmacy and Pharmaceutical Sciences
- Supervision of Honours students in Drug Discovery Biology
- Supervision of PhD students in Drug Discovery Biology
Keywords
- Analytical Pharmacology
- Allosteric Modulation
- Receptor Theory
- Commentary: Drug Discovery
- Pharmaceutical Research
- Drug Side-Effects
- Psychiatric Drugs
- Supervision: Molecular Pharmacology
- Drug Discovery
- Receptors and Signal Transduction
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2004 2023
Discovering novel allosteric probes of muscarinic acetylcholine receptors
Valant, C., Scammells, P. & Christopoulos, A.
10/06/19 → 9/06/22
Project: Research
Translating membrane proteins into therapeutics; from bedside to bench
Sexton, P., Christopoulos, A., Pantelis, C. & Parton, R. G.
1/01/19 → 31/12/23
Project: Research
Adenosine A1 receptor modulation: Structure, dynamics & novel pharmacological interventions
Christopoulos, A., May, L., Imlach, W., Hill, S. & Scott, D.
1/01/18 → 31/12/22
Project: Research
Collaborative Network to Define the Molecular Determinants of G Protein Coupled Receptor Clinical Efficacy
Christopoulos, A., Sexton, P. & Tobin, A. B.
1/11/16 → 31/10/21
Project: Research
Research Output 1993 2019
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity
Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.Research output: Contribution to journal › Article › Research › peer-review
Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H3 receptor antagonists
Riddy, D. M., Cook, A. E., Shackleford, D. M., Pierce, T. L., Mocaer, E., Mannoury la Cour, C., Sors, A., Charman, W. N., Summers, R. J., Sexton, P. M., Christopoulos, A. & Langmead, C. J., 1 Jan 2019, In : Neuropharmacology. 144, p. 244-255 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology
Sengmany, K., Hellyer, S. D., Albold, S., Wang, T., Conn, P. J., May, L. T., Christopoulos, A., Leach, K. & Gregory, K. J., 1 May 2019, In : Neuropharmacology. 149, p. 83-96 14 p.Research output: Contribution to journal › Article › Research › peer-review
Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors
Van Der Westhuizen, E. T., Spathis, A., Khajehali, E., Jorg, M., Mistry, S. N., Capuano, B., Tobin, A. B., Sexton, P. M., Scammells, P. J., Valant, C. & Christopoulos, A., 1 May 2018, In : Molecular Pharmacology. 94, 1, p. 770-783 14 p.Research output: Contribution to journal › Article › Research › peer-review
A Structure-Activity Relationship Study of Bitopic N 6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists
Aurelio, L., Baltos, J. A., Ford, L., Nguyen, A. T. N., Jörg, M., Devine, S. M., Valant, C., White, P. J., Christopoulos, A., May, L. T. & Scammells, P. J., 8 Mar 2018, In : Journal of Medicinal Chemistry. 61, 5, p. 2087-2103 17 p.Research output: Contribution to journal › Article › Research › peer-review
Activities 2011 2011
- 1 Submissions to industry or govt committees, commissions and inquiries
Theme Leader
Arthur Christopoulos (Member)10 Nov 2011
Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries