Projects per year
Personal profile
Monash teaching commitment
- Lectures to second year BPharm students in the Faculty of Pharmacy and Pharmaceutical Sciences
- Lectures to third year BPharmSci students in the Faculty of Pharmacy and Pharmaceutical Sciences
- Supervision of Honours students in Drug Discovery Biology
- Supervision of PhD students in Drug Discovery Biology
Research area keywords
- Analytical Pharmacology
- Allosteric Modulation
- Receptor Theory
- Commentary: Drug Discovery
- Pharmaceutical Research
- Drug Side-Effects
- Psychiatric Drugs
- Supervision: Molecular Pharmacology
- Drug Discovery
- Receptors and Signal Transduction
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2004 2023
Chemical-Biology Approaches to Pathway Selective Adenosine Receptor Ligands
Scammells, P. & Christopoulos, A.
1/07/19 → 30/06/22
Project: Research
Discovering novel allosteric probes of muscarinic acetylcholine receptors
Valant, C., Scammells, P. & Christopoulos, A.
10/06/19 → 9/06/22
Project: Research
Translating membrane proteins into therapeutics; from bedside to bench
Sexton, P., Christopoulos, A., Pantelis, C. & Parton, R. G.
1/01/19 → 31/12/23
Project: Research
Adenosine A1 receptor modulation: Structure, dynamics & novel pharmacological interventions
Christopoulos, A., May, L., Imlach, W., Hill, S. & Scott, D.
1/01/18 → 31/12/22
Project: Research
Research Output 1993 2020
Evaluation of Operational Models of Agonism and Allosterism at Receptors with Multiple Orthosteric Binding Sites
Gregory, K., Giraldo, J., Diao, J., Christopoulos, A. & Leach, K., 2020, In : Molecular Pharmacology. 97, 1, p. 35-45 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity
Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.Research output: Contribution to journal › Article › Research › peer-review
Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs
Hollingsworth, S. A., Kelly, B., Valant, C., Michaelis, J. A., Mastromihalis, O., Thompson, G., Venkatakrishnan, A. J., Hertig, S., Scammells, P. J., Sexton, P. M., Felder, C. C., Christopoulos, A. & Dror, R. O., 1 Dec 2019, In : Nature Communications. 10, 1, p. 1-9 9 p., 3289.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Deconvoluting the Molecular Control of Binding and Signaling at the Amylin 3 Receptor: RAMP3 Alters Signal Propagation through Extracellular Loops of the Calcitonin Receptor
Pham, V., Zhu, Y., Dal Maso, E., Reynolds, C. A., Deganutti, G., Atanasio, S., Hick, C. A., Yang, D., Christopoulos, A., Hay, D. L., Furness, S. G. B., Wang, M-W., Wootten, D. & Sexton, P. M., 18 Mar 2019, In : ACS Pharmacology and Translational Sciences. 2, 3, p. 183-197 15 p.Research output: Contribution to journal › Article › Research › peer-review
4
Citations
(Scopus)
Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H3 receptor antagonists
Riddy, D. M., Cook, A. E., Shackleford, D. M., Pierce, T. L., Mocaer, E., Mannoury la Cour, C., Sors, A., Charman, W. N., Summers, R. J., Sexton, P. M., Christopoulos, A. & Langmead, C. J., 1 Jan 2019, In : Neuropharmacology. 144, p. 244-255 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Activities 2011 2011
- 1 Submissions to industry or govt committees, commissions and inquiries
Theme Leader
Arthur Christopoulos (Member)10 Nov 2011
Activity: External Academic Engagement › Submissions to industry or govt committees, commissions and inquiries