If you made any changes in Pure these will be visible here soon.

Research Output 1989 2019

Filter
Article
Article
10 Citations (Scopus)

The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C∗06: 02 molecule

Mobbs, J. I., Illing, P. T., Dudek, N. L., Brooks, A. G., Baker, D. G., Purcell, A. W., Rossjohn, J. & Vivian, J. P., 20 Oct 2017, In : Journal of Biological Chemistry. 292, 42, p. 17203-17215 13 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

The molecular basis of cross-reactivity in the Australian Snake Venom Detection Kit (SVDK)

Winkel, K., Carroll, T., Williamson, N. A., Ignjatovic, V., Fung, K., Purcell, A. W. & Fry, B. G., 15 Dec 2007, In : Toxicon. 50, 8, p. 1041-1052 12 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The primary immune response to Vaccinia virus vaccination includes cells with a distinct cytotoxic effector CD4 T-cell phenotype

PHIIDO Study Group, 17 Oct 2016, In : Vaccine. 34, 44, p. 5251-5261 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The production, purification and crystallization of a soluble heterdimeric form of a highly selected T-cell receptor in its unliganded and liganded state

Clements, C. S., Kjer-Nielsen, L., Macdonald, W. A., Brooks, A. G., Purcell, A. W., McClusky, J. & Rossjohn, J., 2002, In : Acta Crystallographica Section D: Biological Crystallography. 58, 12, p. 2131 - 2134 4 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state

Clements, C. S., Kjer-Nielsen, L., MacDonald, W. A., Brooks, A. G., Purcell, A. W., McCluskey, J. & Rossjohn, J., 1 Dec 2002, In : Acta Crystallographica Section D: Biological Crystallography. 58, 12, p. 2131-2134 4 p.

Research output: Contribution to journalArticleResearchpeer-review

The production and purification of the human T-cell receptors, the CD3and CD3heterodimers: Complex formation and crystallization with OKT3, a therapeutic monoclonal antibody

Dunstone, M. A., Kjer-Nielsen, L., Kostenko, L., Purcell, A. W., Brooks, A. G., Rossjohn, J. & McCluskey, J., 2004, In : Acta Crystallographica Section D: Biological Crystallography. 60, 8, p. 1425 - 1428 4 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

The production and purification of the human T-cell receptors, the CD3εγ and CD3εδ heterodimers: Complex formation and crystallization with OKT3, a therapeutic monoclonal antibody

Dunstone, M. A., Kjer-Nielsen, L., Kostenko, L., Purcell, A. W., Brooks, A. G., Rossjohn, J. & McCluskey, J., 1 Aug 2004, In : Acta Crystallographica Section D: Biological Crystallography. 60, 8, p. 1425-1428 4 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

The protein import channel in the outer mitosomal membrane of Giardia intestinalis

Dagley, M. J., Dolezal, P., Likic, V. A., Smid, O., Purcell, A. W., Buchanan, S. K., Tachezy, J. & Lithgow, T. J., 2009, In : Molecular Biology and Evolution. 26, 9, p. 1941 - 1947 7 p.

Research output: Contribution to journalArticleResearchpeer-review

71 Citations (Scopus)

The shaping of T cell receptor recognition by self-tolerance

Gras, S., Burrows, S. R., Kjer-Nielsen, L., Clements, C. S., Liu, Y. C., Sullivan, L. C., Bell, M. J., Brooks, A. G., Purcell, A. W., McCluskey, J. & Rossjohn, J., 2009, In : Immunity. 30, 2, p. 193 - 203 11 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

Pang, S. S., Berry, R., Chen, Z., Kjer-Nielsen, L., Perugini, M. A., King, G. F., Wang, C. C., Chew, S. H., La Gruta, N. L., Williams, N. K., Beddoe, T. C., Tiganis, T., Cowieson, N. P., Godfrey, D. I., Purcell, A. W., Wilce, M. CJ., McCluskey, J. & Rossjohn, J., 2010, In : Nature. 467, 7317, p. 844 - 848 7 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

The structure of H-2Kb and Kbm8 complexed to a herpes simplex virus determinant: Evidence for a conformational switch that governs T cell repertoire selection and viral resistance

Webb, A. I., Borg, N. A., Dunstone, M. A., Kjer-Nielsen, L., Beddoe, T. C., McCluskey, J., Carbone, F. R., Bottomley, S. P., Aguilar, M. I., Purcell, A. W. & Rossjohn, J., 2004, In : Journal of Immunology. 173, 1, p. 402 - 409 8 p.

Research output: Contribution to journalArticleResearchpeer-review

65 Citations (Scopus)

The structure of HLA-B8 complexed to an immunodominant viral determinant: Peptide-induced conformational changes and a mode of MHC class I dimerization

Kjer-Nielsen, L., Clements, C. S., Brooks, A. G., Purcell, A. W., Fontes, M. R., McCluskey, J. & Rossjohn, J., 1 Nov 2002, In : Journal of Immunology. 169, 9, p. 5153-5160 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class 1 dimerisation1

Kjer-Nielsen, L., Clements, C. S., Brooks, A. G., Purcell, A. W., Fontes, M. R., McCluskey, J. & Rossjohn, J., 2002, In : Journal of Immunology. 169, 9, p. 5153 - 5160 8 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

The SysteMHC Atlas project

Shao, W., Pedrioli, P. G. A., Wolski, W., Scurtescu, C., Schmid, E., Vizcaíno, J. A., Courcelles, M., Schuster, H., Kowalewski, D., Marino, F., Arlehamn, C. S. L., Vaughan, K., Peters, B., Sette, A., Ottenhoff, T. H. M., Meijgaarden, K. E., Nieuwenhuizen, N., Kaufmann, S. H. E., Schlapbach, R., Castle, J. C. & 26 others, Nesvizhskii, A. I., Nielsen, M., Deutsch, E. W., Campbell, D. S., Moritz, R. L., Zubarev, R. A., Ytterberg, A. J., Purcell, A. W., Marcilla, M., Paradela, A., Wang, Q., Costello, C. E., Ternette, N., Van Veelen, P. A., Van Els, C. A. C. M., Heck, A. J. R., De Souza, G. A., Sollid, L. M., Admon, A., Stevanovic, S., Rammensee, H. G., Thibault, P., Perreault, C., Bassani-Sternberg, M., Aebersold, R. & Caron, E., 1 Jan 2018, In : Nucleic Acids Research. 46, D1, p. D1237-D1247 11 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
File
2 Citations (Scopus)

The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework

Nielsen, L. D., Foged, M. M., Albert, A., Bertelsen, A. B., Søltoft, C. L., Robinson, S. D., Petersen, S. V., Purcell, A. W., Olivera, B. M., Norton, R. S., Vasskog, T., Safavi-Hemami, H., Teilum, K. & Ellgaard, L., 1 Jan 2019, In : Journal of Biological Chemistry. 294, 22, p. 8745-8759 15 p.

Research output: Contribution to journalArticleResearchpeer-review

The use of CRISPR/Cas9 gene editing to confirm congenic contaminations in host-pathogen interaction studies

Ferrand, J., Croft, N. P., Pépin, G., Diener, K. R., Wu, D., Mangan, N. E., Pedersen, J., Behlke, M. A., Hayball, J. D., Purcell, A. W., Ferrero, R. L. & Gantier, M. P., 19 Mar 2018, In : Frontiers in Cellular and Infection Microbiology. 8, 10 p., 87.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

The use of imaging mass spectrometry to study peptide toxin distribution in Australian sea anemones

Mitchell, M. L., Hamilton, B. R., Madio, B., Morales, R. A. V., Tonkin-Hill, G. Q., Papenfuss, A. T., Purcell, A. W., King, G. F., Undheim, E. A. B. & Norton, R. S., 2017, In : Australian Journal of Chemistry. 70, 11, p. 1235-1237 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
53 Citations (Scopus)

Tracking protein aggregation and mislocalization in cells with flow cytometry

Ramdzan, Y. M., Polling, S., Chia, C. P. Z., Ng, I. H. W., Ormsby, A. R., Croft, N. P., Purcell, A. W., Bogoyevitch, M. A., Ng, D. CH., Gleeson, P. A. & Hatters, D. M., 2012, In : Nature Methods. 9, 5, p. 467 - 470 4 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Tumors reveal their secrets to cytotoxic T cells

Williamson, N. A., Rossjohn, J. & Purcell, A. W., 2006, In : Proceedings of the National Academy of Sciences. 103, 40, p. 14649 - 14650 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Twenty years of bioinformatics research for protease-specific substrate and cleavage site prediction: a comprehensive revisit and benchmarking of existing methods

Li, F., Wang, Y., Li, C., Marquez-Lago, T. T., Leier, A., Rawlings, N. D., Haffari, G., Revote, J., Akutsu, T., Chou, K-C., Purcell, A. W., Pike, R. N., Webb, G. I., Smith, A. I., Lithgow, T., Daly, R. J., Whisstock, J. C. & Song, J., 2018, (Accepted/In press) In : Briefings in Bioinformatics. 17 p., bby077.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Unravelling conotoxin folding and molecular diversity

Purcell, A. W. & Safavi-Hemami, H., 2012, In : Australian Biochemist. 43, 2, p. 4 - 6 3 p.

Research output: Contribution to journalArticleOther

3 Citations (Scopus)

Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response

Rawlinson, S. M., Zhao, T., Rozario, A. M., Rootes, C. L., McMillan, P. J., Purcell, A. W., Woon, A., Marsh, G. A., Lieu, K. G., Wang, L-F., Netter, H. J., Bell, T. D. M., Stewart, C. R. & Moseley, G. W., 3 Aug 2018, In : Nature Communications. 9, 1, 12 p., 3057.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
24 Citations (Scopus)

β2-glycoprotein I and protection from anti-SSA/Ro60- associated cardiac manifestations of neonatal lupus

Reed, J. H., Clancy, R. M., Purcell, A. W., Kim, M. Y., Gordon, T. P. & Buyon, J. P., 1 Jul 2011, In : Journal of Immunology. 187, 1, p. 520-526 7 p.

Research output: Contribution to journalArticleOtherpeer-review