Research Output per year
Research Output 1989 2019
- 150 - 200 out of 223 results
- Type (ascending)
Quantifying epitope presentation using mass spectrometry
Croft, N. P., Purcell, A. W. & Tscharke, D. C., 2015, In : Molecular Immunology. 68, 2 - Part A, p. 77 - 80 4 p.Research output: Contribution to journal › Article › Other › peer-review
Quantitative and qualitative influences of tapasin on the class I peptide repertoire
Purcell, A. W., Gorman, J. J., Garcia-Peydró, M., Paradela, A., Burrows, S. R., Talbo, G. H., Laham, N., Chen Au Peh, A. P., Reynolds, E. C., López de Castro, J. A. & McCluskey, J., 15 Jan 2001, In : Journal of Immunology. 166, 2, p. 1016-1027 12 p.Research output: Contribution to journal › Article › Research › peer-review
Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain
Dagley, L. F., White, C. A., Liao, Y., Shi, W., Smyth, G. K., Orian, J. M., Emili, A. & Purcell, A. W., 2014, In : Proteomics. 14, 2-3, p. 241 - 261 21 p.Research output: Contribution to journal › Article › Research › peer-review
Quokka: A comprehensive tool for rapid and accurate prediction of kinase family-specific phosphorylation sites in the human proteome
Li, F., Li, C., Marquez-Lago, T. T., Leier, A., Akutsu, T., Purcell, A. W., Smith, A. I., Lithgow, T., Daly, R. J., Song, J. & Chou, K-C., 15 Dec 2018, In : Bioinformatics. 34, 24, p. 4223-4231 9 p., bty522.Research output: Contribution to journal › Article › Research › peer-review
Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides
Safavi-Hemami, H., Li, Q., Jackson, R. L., Song, A. S., Boomsma, W., Bandyopadhyay, P. K., Gruber, C. W., Purcell, A. W., Yandell, M., Olivera, B. M. & Ellgaard, L., 22 Mar 2016, In : Proceedings of the National Academy of Sciences. 113, 12, p. 3227-3232 6 p.Research output: Contribution to journal › Article › Research › peer-review
Rapid microscale in-gel processing and digestion of proteins using surface acoustic waves
Kulkarni, K., Ramarathinam, S., Friend, J., Yeo, L., Purcell, A. & Perlmutter, P., 2010, In : Lab on a Chip. 10, 12, p. 1518 - 1520 3 p.Research output: Contribution to journal › Article › Research › peer-review
Reactivity with dichotomous determinants of Ro 60 stratifies autoantibody responses in lupus and primary Sjogren's syndrome
Reed, J. H., Dudek, N. L., Osborne, S. E., Kaufmann, K. M., Jackson, M. W., Purcell, A. W. & Gordon, T. P., 2010, In : Arthritis and Rheumatism. 62, 5, p. 1448 - 1456 9 p.Research output: Contribution to journal › Article › Research › peer-review
Refinement in the production and purification of recombinant HCMV IE1-pp65 protein for the generation of epitope-specific T cell immunity
Nguyen, T. H. O., Mifsud, N. A., Stewart, L. A., Rose, M. J., Etto, T. L., Williamson, N. A., Purcell, A. W., Kotsimbos, T. C. & Schwarer, A., 2008, In : Protein Expression and Purification. 61, 1, p. 22 - 30 9 p.Research output: Contribution to journal › Article › Research › peer-review
Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP
Krishnamurthy, B., Dudek, N. L., McKenzie, M. D., Purcell, A. W., Brooks, A. G., Gellert, S., Colman, P. G., Harrison, L. C., Lew, A. M., Thomas, H. E. & Kay, T. W. H., 1 Dec 2006, In : Journal of Clinical Investigation. 116, 12, p. 3258-3265 8 p.Research output: Contribution to journal › Article › Research › peer-review
Response to Comment on "A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands"
Faridi, P., Li, C., Ramarathinam, S. H., Illing, P. T., Mifsud, N. A., Ayala, R., Song, J., Gearing, L. J., Croft, N. P. & Purcell, A. W., 16 Aug 2019, In : Science Immunology. 4, 38, 4 p., eaaw8457.Research output: Contribution to journal › Article › Other › peer-review
Restricted specificity of intermolecular spreading to endogenous La (SS-B) and 60 kDA Ro (SS-A) in experimental autoimmunity
Gordon, T. P., Kinoshita, G., Cavill, D., Keech, C., Farris, A. D., Kaufman, K., McCluskey, J. & Purcell, A. W., 27 Jul 2002, In : Scandinavian Journal of Immunology. 56, 2, p. 168-173 6 p.Research output: Contribution to journal › Article › Research › peer-review
Revisiting the arthritogenic peptide theory: quantitative not qualitative changes in the peptide repertoire of HLA-B27 allotypes
Schittenhelm, R. B., Lim Kam Sian, T. C. C., Wilmann, P. G., Dudek, N. L. & Purcell, A. W., 2015, In : Arthritis and Rheumatology. 67, 3, p. 702 - 713 12 p.Research output: Contribution to journal › Article › Research › peer-review
RP-HPLC binding domains of proteins
Aguilar, M-I., Clayton, D. J., Holt, P., Kronina, V., Boysen, R. I., Purcell, A. W. & Hearn, M. T. W., 1998, In : Analytical Chemistry. p. 5010 - 5018 9 p.Research output: Contribution to journal › Article › Research › peer-review
Secreted HLA recapitulates the immunopeptidome and allows in-depth coverage of HLA A*02: 01 ligands
Scull, K. E., Dudek, N. L., Corbett, A. J., Ramarathinam, S. H., Gorasia, D. G., Williamson, N. A. & Purcell, A. W., Jun 2012, In : Molecular Immunology. 51, 2, p. 136-142 7 p.Research output: Contribution to journal › Article › Research › peer-review
Serum phosphorylated neurofilament-heavy chain levels in multiple sclerosis patients
Gresle, M. M., Liu, Y., Dagley, L. F., Haartsen, J., Pearson, F., Purcell, A. W., Laverick, L., Petzold, A., Lucas, R. M., van der Walt, A., Prime, H., Lazarus, K-J. L., Taylor, B. V., Morris, D. R., Shaw, G. P. J. & Butzkueven, H., 1 Nov 2014, In : Journal of Neurology, Neurosurgery and Psychiatry. 85, 11, p. 1209-1213 5 p.Research output: Contribution to journal › Article › Research › peer-review
Simultaneous quantification of viral antigen expression kinetics using data-independent (DIA) mass spectrometry
Croft, N. P., de Verteuil, D. A., Smith, S. A., Wong, Y. C., Schittenhelm, R. B., Tscharke, D. C. & Purcell, A. W., 2015, In : Molecular & Cellular Proteomics. 14, 5, p. 1361 - 1372 12 p.Research output: Contribution to journal › Article › Research › peer-review
Specialisation of the venom gland proteome in predatory cone snails reveals functional diversification of the conotoxin biosynthetic pathway
Safavi-Hemami, H., Siero, W. A., Gorasia, D. G., Young, N. D., MacMillan, D., Williamson, N. A. & Purcell, A. W., 2 Sep 2011, In : Journal of Proteome Research. 10, 9, p. 3904-3919 16 p.Research output: Contribution to journal › Article › Research › peer-review
Specialized insulin is used for chemical warfare by fish-hunting cone snails
Safavi-Hemami, H., Gajewiak, J., Karanth, S., Robinson, S., Ueberheide, B., Douglass, A. D., Schlegel, A., Imperial, J. S., Watkins, M., Bandyopadhyay, P. K., Yandell, M., Li, Q., Purcell, A. W., Norton, R. S., Ellgaard, L. & Olivera, B. M., 2015, In : Proceedings of the National Academy of Sciences. 112, 6, p. 1743 - 1748 6 p.Research output: Contribution to journal › Article › Research › peer-review
Spreading of the immune response from 52 kDaRo and 60 kDaRo to calreticulin in experimental autoimmunity
Kinoshita, G., Keech, C. L., Sontheimer, R. D., Purcell, A., McCluskey, J. & Gordon, T. P., 9 Feb 1998, In : Lupus. 7, 1, p. 7-11 5 p.Research output: Contribution to journal › Article › Research › peer-review
Stable isotope shifted matrices enable the use of low mass ion precursor scanning for targeted metabolite identification
Reilly, C. B., Ramarathinam, S. H., Williamson, N. A. & Purcell, A. W., 17 Jan 2011, In : Proteome Science. 9, 7 p., 2.Research output: Contribution to journal › Article › Research › peer-review
Structural and biological basis of CTL escape in coronavirus-infected mice
Butler, N. S., Theodossis, A., Webb, A. I., Dunstone, M. A., Nastovska, R., Ramarathinam, S. H., Rossjohn, J., Purcell, A. W. & Perlman, S., 2008, In : Journal of Immunology. 180, 6, p. 3926 - 3937 12 p.Research output: Contribution to journal › Article › Research › peer-review
Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes
Trujillo, J. A., Gras, S., Twist, K-A., Croft, N. P., Channappanavar, R., Rossjohn, J., Purcell, A. W. & Perlman, S., 2014, In : Journal of Immunology. 192, 11, p. 5245 - 5256 12 p.Research output: Contribution to journal › Article › Research › peer-review
Structural and regulatory diversity shape HLA-C protein expression levels
Kaur, G., Gras, S., Mobbs, J. I., Vivian, J. P., Cortes, A., Barber, T., Kuttikkatte, S. B., Jensen, L. T., Attfield, K. E., Dendrou, C. A., Carrington, M., McVean, G., Purcell, A. W., Rossjohn, J. & Fugger, L., 26 Jun 2017, In : Nature Communications. 8, 12 p., 15924.Research output: Contribution to journal › Article › Research › peer-review
Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses
Day, E. B., Guillonneau, C., Gras, S., La Gruta, N. L., Vignali, D., Doherty, P., Purcell, A., Rossjohn, J. & Turner, S., 2011, In : Proceedings of the National Academy of Sciences. 108, 23, p. 9536 - 9541 6 p.Research output: Contribution to journal › Article › Research › peer-review
Synergistic Combination of Polymyxin B and Enrofloxacin Induced Metabolic Perturbations in Extensive Drug-resistant Pseudomonas aeruginosa
Lin, Y-W., Han, M-L., Zhao, J., Zhu, Y., Rao, G., Forrest, A., Song, J., Kaye, K. S., Hertzog, P., Purcell, A., Creek, D., Zhou, T. Q., Velkov, T. & Li, J., 3 Oct 2019, In : Frontiers in Pharmacology. 10, 11 p., 1146.Research output: Contribution to journal › Article › Research › peer-review
Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length
Newcombe, E. A., Ruff, K. M., Sethi, A., Ormsby, A. R., Ramdzan, Y. M., Fox, A. H., Purcell, A. W., Gooley, P. R., Pappu, R. V. & Hatters, D. M., 11 May 2018, In : Journal of Molecular Biology. 430, 10, p. 1442-1458 17 p.Research output: Contribution to journal › Article › Research › peer-review
Tapasin-mediated retention and optimization of peptide ligands during the assembly of class I molecules
Barnden, M. J., Purcell, A. W., Gorman, J. J. & McCluskey, J., 1 Jul 2000, In : Journal of Immunology. 165, 1, p. 322-330 9 p.Research output: Contribution to journal › Article › Research › peer-review
TAP genes and immunity
McCluskey, J., Rossjohn, J. & Purcell, A. W., 2004, In : Current Opinion in Immunology. 16, 5, p. 651 - 659 9 p.Research output: Contribution to journal › Article › Research › peer-review
T cell allorecognition via molecular mimicry
Macdonald, W. A., Chen, Z., Gras, S., Archbold, J. K., Tynan, F. E., Clements, C. S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P. M., Wilce, M. C. J., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A., Purcell, A. W., Kappler, J., Burrows, S. R., Rossjohn, J. & McCluskey, J., 2009, In : Immunity. 31, 6, p. 897 - 908 12 p.Research output: Contribution to journal › Article › Research › peer-review
T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids
Wun, K. S., Reijneveld, J. F., Cheng, T. Y., Ladell, K., Uldrich, A. P., Le Nours, J., Miners, K. L., McLaren, J. E., Grant, E. J., Haigh, O. L., Watkins, T. S., Suliman, S., Iwany, S., Jimenez, J., Calderon, R., Tamara, K. L., Leon, S. R., Murray, M. B., Mayfield, J. A., Altman, J. D. & 8 others, , 1 Apr 2018, In : Nature Immunology. 19, 4, p. 397-406 10 p.Research output: Contribution to journal › Article › Research › peer-review
T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles
Law, S. C. C., Street, S., Yu, C. H. A., Capini, C., Ramnoruth, S., Nel, H. J., van Gorp, E., Hyde, C., Lau, K., Pahau, H., Purcell, A. W. & Thomas, R., 17 May 2012, In : Arthritis Research and Therapy. 14, 3, R118.Research output: Contribution to journal › Article › Research › peer-review
T cell cross-reactivity between a highly immunogenic EBV epitope and a self-peptide naturally presented by HLA-B*18:01+ cells
Rist, M. J., Hibbert, K. M., Croft, N. P., Smith, C., Neller, M. A., Burrows, J. M., Miles, J. J., Purcell, A. W., Rossjohn, J., Gras, S. & Burrows, S. R., 2015, In : Journal of Immunology. 194, 10, p. 4668 - 4675 8 p.Research output: Contribution to journal › Article › Research › peer-review
T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo
Webb, A. I., Dunstone, M. A., Williamson, N. A., Price, J. D., de Kauwe, A., Chen, W., Oakley, A. J., Perlmutter, P., McCluskey, J., Aguilar, M-I., Rossjohn, J. & Purcell, A. W., 2005, In : Journal of Immunology. 175, 6, p. 3810 - 3818 9 p.Research output: Contribution to journal › Article › Research › peer-review
T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
Tynan, F. E., Burrows, S. R., Buckle, A. M., Clements, C. S., Borg, N. A., Miles, J. J., Beddoe, T. C., Whisstock, J. C., Wilce, M. C. J., Silins, S. L., Burrows, J. M., Kjer-Nielsen, L., Kostenko, L., Purcell, A. W., McCluskey, J. & Rossjohn, J., 2005, In : Nature Immunology. 6, 11, p. 1114 - 1122 9 p.Research output: Contribution to journal › Article › Research › peer-review
T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex
Beringer, D. X., Kleijwegt, F. S., Wiede, F., Van Der Slik, A. R., Loh, K. K. L., Petersen, J., Dudek, N. L., Duinkerken, G., Laban, S., Joosten, A. M., Vivian, J. P., Chen, Z., Uldrich, A. P., Godfrey, D. I., McCluskey, J., Price, D. A., Radford, K. J., Purcell, A. W., Nikolic, T., Reid, H. H. & 3 others, , 2015, In : Nature Immunology. 16, 11, p. 1153 - 1161 9 p.Research output: Contribution to journal › Article › Research › peer-review
T-cells behaving badly: Structural insights into alloreactivity and autoimmunity
Ely, L. K., Burrows, S. R., Purcell, A. W., Rossjohn, J. & McCluskey, J., 2008, In : Current Opinion in Immunology. 20, 5, p. 575 - 580 6 p.Research output: Contribution to journal › Article › Research › peer-review
The 1.5 Å crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance
Kjer-Nielsen, L., Clements, C. S., Brooks, A. G., Purcell, A. W., McCluskey, J. & Rossjohn, J., 1 Nov 2002, In : Structure. 10, 11, p. 1521-1532 12 p.Research output: Contribution to journal › Article › Research › peer-review
The 1.5 Crystal Structure of a Highly Selected Antiviral T Cell Receptor Provides Evidence for a Structural Basis of Immonodominance
Kjer-Nielsen, L., Clements, C. S., Brooks, A. G., Purcell, A. W., McClusky, J. & Rossjohn, J., 2002, In : Structure. 10, 11, p. 1521 - 1532 12 p.Research output: Contribution to journal › Article › Research › peer-review
The accessibility of the prosthetic group biotin during monomeric avidin affinity chromatography
Purcell, A. W. & Wallace, J. C., 1 Jan 1996, In : Analytical Biochemistry. 238, 2, p. 213-216 4 p.Research output: Contribution to journal › Article › Research › peer-review
The A-chain of insulin is a hot-spot for CD4 + T cell epitopes in human type 1 diabetes
Mannering, S. I., Pang, S. H., Williamson, N. A., Naselli, G., Reynolds, E. C., O'Brien-Simpson, N. M., Purcell, A. W. & Harrison, L. C., May 2009, In : Clinical and Experimental Immunology. 156, 2, p. 226-231 6 p.Research output: Contribution to journal › Article › Other › peer-review
The beta cell immunopeptidome
Dudek, N. L. & Purcell, A. W., 2014, In : Vitamins and Hormones-Advances in Research and Applications. 95, p. 115 - 144 30 p.Research output: Contribution to journal › Article › Research › peer-review
The CDR3 regions of an Immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition
Borg, N. A., Ely, L. K., Beddoe, T. C., Macdonald, W. A., Reid, H. H., Clements, C. S., Purcell, A. W., Kjer-Nielsen, L., Miles, J. J., Burrows, S. R., McCluskey, J. & Rossjohn, J., 2005, In : Nature Immunology. 6, 2, p. 171 - 180 10 p.Research output: Contribution to journal › Article › Research › peer-review
The cellular redox environment alters antigen presentation
Trujillo, J. A., Croft, N. P., Dudek, N. L., Channappanavar, R., Theodossis, A., Webb, A. I., Dunstone, M. A., Illing, P. TT., Butler, N. S., Fett, C., Tscharke, D. C., Rossjohn, J., Perlman, S. & Purcell, A. W., 2014, In : Journal of Biological Chemistry. 289, 40, p. 27979 - 27991 13 p.Research output: Contribution to journal › Article › Research › peer-review
The central role played by peptides in the immune response and the design of peptide-based vaccines against infectious diseases and cancer
Jackson, D. C., Purcell, A. W., Fitzmaurice, C. J., Zeng, W. & Hart, D. N. J., 1 Jan 2002, In : Current Drug Targets. 3, 2, p. 175-196 22 p.Research output: Contribution to journal › Article › Research › peer-review
The enantioselective total synthesis and unambiguous proof of the absolute stereochemistry of pervilleine C
Kulkarni, K. P., Zhao, A. Y., Purcell, A. W. & Perlmutter, P., 2008, In : Synlett. 2008, 14, p. 2209 - 2212 4 p.Research output: Contribution to journal › Article › Research › peer-review
The energetic basis underpinning T-cell receptor recognition of a super-bulged peptide bound to a major histocompatibility complex class I molecule
Liu, Y. C., Chen, Z., Burrows, S. R., Purcell, A. W., McCluskey, J., Rossjohn, J. & Gras, S., 2012, In : Journal of Biological Chemistry. 287, 15, p. 12267 - 12276 10 p.Research output: Contribution to journal › Article › Research › peer-review
The Evolving Landscape of Autoantigen Discovery and Characterization in Type 1 Diabetes
Purcell, A. W., Sechi, S. & DiLorenzo, T. P., 1 May 2019, In : Diabetes. 68, 5, p. 879-886 8 p.Research output: Contribution to journal › Article › Research › peer-review
The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation
Tynan, F. E., Elhassen, D., Purcell, A. W., Burrows, J. M., Borg, N. A., Miles, J. J., Williamson, N. A., Green, K. J., Tellam, J., Kjer-Nielsen, L., McCluskey, J., Rossjohn, J. & Burrows, S. R., 2005, In : Journal of Experimental Medicine. 202, 9, p. 1249 - 1260 12 p.Research output: Contribution to journal › Article › Research › peer-review
The insulin A-chain epitope recognized by human T cells is posttranslationally modified
Mannering, S. I., Harrison, L. C., Williamson, N. A., Morris, J. S., Thearle, D. J., Jensen, K. P., Kay, T. W., Rossjohn, J., Falk, B. A., Nepom, G. T. & Purcell, A. W., 2005, In : Journal of Experimental Medicine. 202, 9, p. 1191 - 1197 7 p.Research output: Contribution to journal › Article › Research › peer-review
The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis
Ting, Y. T., Petersen, J., Ramarathinam, S. H., Scally, S. W., Loh, K. L., Thomas, R., Suri, A., Baker, D. G., Purcell, A. W., Reid, H. H. & Rossjohn, J., 2 Mar 2018, In : Journal of Biological Chemistry. 293, 9, p. 3236-3251 16 p.Research output: Contribution to journal › Article › Research › peer-review