Research Output per year
Research Output
Article
Proteomic interrogation of venom delivery in marine cone snails: Novel insights into the role of the venom bulb
Safavi-Hemami, H., Young, N. D., Williamson, N. A. & Purcell, A. W., 5 Nov 2010, In : Journal of Proteome Research. 9, 11, p. 5610-5619 10 p.Research output: Contribution to journal › Article › Other › peer-review
25
Citations
(Scopus)
Qualitative and quantitative differences in peptides bound to HLA-B27 in the presence of mouse versus human tapasin define a role for tapasin as a size-dependent peptide editor
Sesma, L., Galocha, B., Vázquez, M., Purcell, A. W., Marcilla, M., McCluskey, J. & López De Castro, J. A., 15 Jun 2005, In : Journal of Immunology. 174, 12, p. 7833-7844 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
15
Citations
(Scopus)
Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses
Wu, T., Guan, J., Handel, A., Tscharke, D. C., Sidney, J., Sette, A., Wakim, L. M., Sng, X. Y. X., Thomas, P. G., Croft, N. P., Purcell, A. W. & La Gruta, N. L., 28 Jun 2019, In : Nature Communications. 10, 1, 14 p., 2846.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
10
Citations
(Scopus)
Quantifying epitope presentation using mass spectrometry
Croft, N. P., Purcell, A. W. & Tscharke, D. C., 2015, In : Molecular Immunology. 68, 2 - Part A, p. 77 - 80 4 p.Research output: Contribution to journal › Article › Other › peer-review
20
Citations
(Scopus)
Quantitative and qualitative influences of tapasin on the class I peptide repertoire
Purcell, A. W., Gorman, J. J., Garcia-Peydró, M., Paradela, A., Burrows, S. R., Talbo, G. H., Laham, N., Chen Au Peh, A. P., Reynolds, E. C., López de Castro, J. A. & McCluskey, J., 15 Jan 2001, In : Journal of Immunology. 166, 2, p. 1016-1027 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
127
Citations
(Scopus)
Quantitative proteomic profiling reveals novel region-specific markers in the adult mouse brain
Dagley, L. F., White, C. A., Liao, Y., Shi, W., Smyth, G. K., Orian, J. M., Emili, A. & Purcell, A. W., 2014, In : Proteomics. 14, 2-3, p. 241 - 261 21 p.Research output: Contribution to journal › Article › Research › peer-review
5
Citations
(Scopus)
Quokka: A comprehensive tool for rapid and accurate prediction of kinase family-specific phosphorylation sites in the human proteome
Li, F., Li, C., Marquez-Lago, T. T., Leier, A., Akutsu, T., Purcell, A. W., Smith, A. I., Lithgow, T., Daly, R. J., Song, J. & Chou, K-C., 15 Dec 2018, In : Bioinformatics. 34, 24, p. 4223-4231 9 p., bty522.Research output: Contribution to journal › Article › Research › peer-review
42
Citations
(Scopus)
Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides
Safavi-Hemami, H., Li, Q., Jackson, R. L., Song, A. S., Boomsma, W., Bandyopadhyay, P. K., Gruber, C. W., Purcell, A. W., Yandell, M., Olivera, B. M. & Ellgaard, L., 22 Mar 2016, In : Proceedings of the National Academy of Sciences. 113, 12, p. 3227-3232 6 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
21
Citations
(Scopus)
Rapid microscale in-gel processing and digestion of proteins using surface acoustic waves
Kulkarni, K., Ramarathinam, S., Friend, J., Yeo, L., Purcell, A. & Perlmutter, P., 2010, In : Lab on a Chip. 10, 12, p. 1518 - 1520 3 p.Research output: Contribution to journal › Article › Research › peer-review
14
Citations
(Scopus)
Reactivity with dichotomous determinants of Ro 60 stratifies autoantibody responses in lupus and primary Sjogren's syndrome
Reed, J. H., Dudek, N. L., Osborne, S. E., Kaufmann, K. M., Jackson, M. W., Purcell, A. W. & Gordon, T. P., 2010, In : Arthritis and Rheumatism. 62, 5, p. 1448 - 1456 9 p.Research output: Contribution to journal › Article › Research › peer-review
9
Citations
(Scopus)
Refinement in the production and purification of recombinant HCMV IE1-pp65 protein for the generation of epitope-specific T cell immunity
Nguyen, T. H. O., Mifsud, N. A., Stewart, L. A., Rose, M. J., Etto, T. L., Williamson, N. A., Purcell, A. W., Kotsimbos, T. C. & Schwarer, A., 2008, In : Protein Expression and Purification. 61, 1, p. 22 - 30 9 p.Research output: Contribution to journal › Article › Research › peer-review
3
Citations
(Scopus)
Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP
Krishnamurthy, B., Dudek, N. L., McKenzie, M. D., Purcell, A. W., Brooks, A. G., Gellert, S., Colman, P. G., Harrison, L. C., Lew, A. M., Thomas, H. E. & Kay, T. W. H., 1 Dec 2006, In : Journal of Clinical Investigation. 116, 12, p. 3258-3265 8 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
166
Citations
(Scopus)
Response to Comment on "A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands"
Faridi, P., Li, C., Ramarathinam, S. H., Illing, P. T., Mifsud, N. A., Ayala, R., Song, J., Gearing, L. J., Croft, N. P. & Purcell, A. W., 16 Aug 2019, In : Science Immunology. 4, 38, 4 p., eaaw8457.Research output: Contribution to journal › Article › Other › peer-review
Open Access
3
Citations
(Scopus)
Restricted specificity of intermolecular spreading to endogenous La (SS-B) and 60 kDA Ro (SS-A) in experimental autoimmunity
Gordon, T. P., Kinoshita, G., Cavill, D., Keech, C., Farris, A. D., Kaufman, K., McCluskey, J. & Purcell, A. W., 27 Jul 2002, In : Scandinavian Journal of Immunology. 56, 2, p. 168-173 6 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
12
Citations
(Scopus)
Revisiting the arthritogenic peptide theory: quantitative not qualitative changes in the peptide repertoire of HLA-B27 allotypes
Schittenhelm, R. B., Lim Kam Sian, T. C. C., Wilmann, P. G., Dudek, N. L. & Purcell, A. W., 2015, In : Arthritis and Rheumatology. 67, 3, p. 702 - 713 12 p.Research output: Contribution to journal › Article › Research › peer-review
55
Citations
(Scopus)
RP-HPLC binding domains of proteins
Aguilar, M-I., Clayton, D. J., Holt, P., Kronina, V., Boysen, R. I., Purcell, A. W. & Hearn, M. T. W., 1998, In : Analytical Chemistry. p. 5010 - 5018 9 p.Research output: Contribution to journal › Article › Research › peer-review
26
Citations
(Scopus)
Secreted HLA recapitulates the immunopeptidome and allows in-depth coverage of HLA A*02: 01 ligands
Scull, K. E., Dudek, N. L., Corbett, A. J., Ramarathinam, S. H., Gorasia, D. G., Williamson, N. A. & Purcell, A. W., Jun 2012, In : Molecular Immunology. 51, 2, p. 136-142 7 p.Research output: Contribution to journal › Article › Research › peer-review
30
Citations
(Scopus)
Serum phosphorylated neurofilament-heavy chain levels in multiple sclerosis patients
Gresle, M. M., Liu, Y., Dagley, L. F., Haartsen, J., Pearson, F., Purcell, A. W., Laverick, L., Petzold, A., Lucas, R. M., van der Walt, A., Prime, H., Lazarus, K-J. L., Taylor, B. V., Morris, D. R., Shaw, G. P. J. & Butzkueven, H., 1 Nov 2014, In : Journal of Neurology, Neurosurgery and Psychiatry. 85, 11, p. 1209-1213 5 p.Research output: Contribution to journal › Article › Research › peer-review
19
Citations
(Scopus)
Simultaneous quantification of viral antigen expression kinetics using data-independent (DIA) mass spectrometry
Croft, N. P., de Verteuil, D. A., Smith, S. A., Wong, Y. C., Schittenhelm, R. B., Tscharke, D. C. & Purcell, A. W., 2015, In : Molecular & Cellular Proteomics. 14, 5, p. 1361 - 1372 12 p.Research output: Contribution to journal › Article › Research › peer-review
14
Citations
(Scopus)
Specialisation of the venom gland proteome in predatory cone snails reveals functional diversification of the conotoxin biosynthetic pathway
Safavi-Hemami, H., Siero, W. A., Gorasia, D. G., Young, N. D., MacMillan, D., Williamson, N. A. & Purcell, A. W., 2 Sep 2011, In : Journal of Proteome Research. 10, 9, p. 3904-3919 16 p.Research output: Contribution to journal › Article › Research › peer-review
31
Citations
(Scopus)
Specialized insulin is used for chemical warfare by fish-hunting cone snails
Safavi-Hemami, H., Gajewiak, J., Karanth, S., Robinson, S., Ueberheide, B., Douglass, A. D., Schlegel, A., Imperial, J. S., Watkins, M., Bandyopadhyay, P. K., Yandell, M., Li, Q., Purcell, A. W., Norton, R. S., Ellgaard, L. & Olivera, B. M., 2015, In : Proceedings of the National Academy of Sciences. 112, 6, p. 1743 - 1748 6 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
66
Citations
(Scopus)
Spreading of the immune response from 52 kDaRo and 60 kDaRo to calreticulin in experimental autoimmunity
Kinoshita, G., Keech, C. L., Sontheimer, R. D., Purcell, A., McCluskey, J. & Gordon, T. P., 9 Feb 1998, In : Lupus. 7, 1, p. 7-11 5 p.Research output: Contribution to journal › Article › Research › peer-review
34
Citations
(Scopus)
Stable isotope shifted matrices enable the use of low mass ion precursor scanning for targeted metabolite identification
Reilly, C. B., Ramarathinam, S. H., Williamson, N. A. & Purcell, A. W., 17 Jan 2011, In : Proteome Science. 9, 7 p., 2.Research output: Contribution to journal › Article › Research › peer-review
Open Access
1
Citation
(Scopus)
Structural and biological basis of CTL escape in coronavirus-infected mice
Butler, N. S., Theodossis, A., Webb, A. I., Dunstone, M. A., Nastovska, R., Ramarathinam, S. H., Rossjohn, J., Purcell, A. W. & Perlman, S., 2008, In : Journal of Immunology. 180, 6, p. 3926 - 3937 12 p.Research output: Contribution to journal › Article › Research › peer-review
15
Citations
(Scopus)
Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes
Trujillo, J. A., Gras, S., Twist, K-A., Croft, N. P., Channappanavar, R., Rossjohn, J., Purcell, A. W. & Perlman, S., 2014, In : Journal of Immunology. 192, 11, p. 5245 - 5256 12 p.Research output: Contribution to journal › Article › Research › peer-review
6
Citations
(Scopus)
Structural and regulatory diversity shape HLA-C protein expression levels
Kaur, G., Gras, S., Mobbs, J. I., Vivian, J. P., Cortes, A., Barber, T., Kuttikkatte, S. B., Jensen, L. T., Attfield, K. E., Dendrou, C. A., Carrington, M., McVean, G., Purcell, A. W., Rossjohn, J. & Fugger, L., 26 Jun 2017, In : Nature Communications. 8, 12 p., 15924.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
30
Citations
(Scopus)
Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8+ T-cell responses
Day, E. B., Guillonneau, C., Gras, S., La Gruta, N. L., Vignali, D., Doherty, P., Purcell, A., Rossjohn, J. & Turner, S., 2011, In : Proceedings of the National Academy of Sciences. 108, 23, p. 9536 - 9541 6 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
27
Citations
(Scopus)
Synergistic Combination of Polymyxin B and Enrofloxacin Induced Metabolic Perturbations in Extensive Drug-resistant Pseudomonas aeruginosa
Lin, Y-W., Han, M-L., Zhao, J., Zhu, Y., Rao, G., Forrest, A., Song, J., Kaye, K. S., Hertzog, P., Purcell, A., Creek, D., Zhou, T. Q., Velkov, T. & Li, J., 3 Oct 2019, In : Frontiers in Pharmacology. 10, 11 p., 1146.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length
Newcombe, E. A., Ruff, K. M., Sethi, A., Ormsby, A. R., Ramdzan, Y. M., Fox, A. H., Purcell, A. W., Gooley, P. R., Pappu, R. V. & Hatters, D. M., 11 May 2018, In : Journal of Molecular Biology. 430, 10, p. 1442-1458 17 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
10
Citations
(Scopus)
Tapasin-mediated retention and optimization of peptide ligands during the assembly of class I molecules
Barnden, M. J., Purcell, A. W., Gorman, J. J. & McCluskey, J., 1 Jul 2000, In : Journal of Immunology. 165, 1, p. 322-330 9 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
82
Citations
(Scopus)
TAP genes and immunity
McCluskey, J., Rossjohn, J. & Purcell, A. W., 2004, In : Current Opinion in Immunology. 16, 5, p. 651 - 659 9 p.Research output: Contribution to journal › Article › Research › peer-review
44
Citations
(Scopus)
T cell allorecognition via molecular mimicry
Macdonald, W. A., Chen, Z., Gras, S., Archbold, J. K., Tynan, F. E., Clements, C. S., Bharadwaj, M., Kjer-Nielsen, L., Saunders, P. M., Wilce, M. C. J., Crawford, F., Stadinsky, B., Jackson, D., Brooks, A., Purcell, A. W., Kappler, J., Burrows, S. R., Rossjohn, J. & McCluskey, J., 2009, In : Immunity. 31, 6, p. 897 - 908 12 p.Research output: Contribution to journal › Article › Research › peer-review
162
Citations
(Scopus)
T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids
Wun, K. S., Reijneveld, J. F., Cheng, T. Y., Ladell, K., Uldrich, A. P., Le Nours, J., Miners, K. L., McLaren, J. E., Grant, E. J., Haigh, O. L., Watkins, T. S., Suliman, S., Iwany, S., Jimenez, J., Calderon, R., Tamara, K. L., Leon, S. R., Murray, M. B., Mayfield, J. A., Altman, J. D. & 8 others, , 1 Apr 2018, In : Nature Immunology. 19, 4, p. 397-406 10 p.Research output: Contribution to journal › Article › Research › peer-review
11
Citations
(Scopus)
T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles
Law, S. C. C., Street, S., Yu, C. H. A., Capini, C., Ramnoruth, S., Nel, H. J., van Gorp, E., Hyde, C., Lau, K., Pahau, H., Purcell, A. W. & Thomas, R., 17 May 2012, In : Arthritis Research and Therapy. 14, 3, R118.Research output: Contribution to journal › Article › Research › peer-review
Open Access
76
Citations
(Scopus)
T cell cross-reactivity between a highly immunogenic EBV epitope and a self-peptide naturally presented by HLA-B*18:01+ cells
Rist, M. J., Hibbert, K. M., Croft, N. P., Smith, C., Neller, M. A., Burrows, J. M., Miles, J. J., Purcell, A. W., Rossjohn, J., Gras, S. & Burrows, S. R., 2015, In : Journal of Immunology. 194, 10, p. 4668 - 4675 8 p.Research output: Contribution to journal › Article › Research › peer-review
6
Citations
(Scopus)
T cell determinants incorporating beta-amino acid residues are protease resistant and remain immunogenic in vivo
Webb, A. I., Dunstone, M. A., Williamson, N. A., Price, J. D., de Kauwe, A., Chen, W., Oakley, A. J., Perlmutter, P., McCluskey, J., Aguilar, M-I., Rossjohn, J. & Purcell, A. W., 2005, In : Journal of Immunology. 175, 6, p. 3810 - 3818 9 p.Research output: Contribution to journal › Article › Research › peer-review
48
Citations
(Scopus)
T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease
Petersen, J., Ciacchi, L., Tran, M. T., Loh, K. L., Kooy-Winkelaar, Y., Croft, N. P., Hardy, M. Y., Chen, Z., McCluskey, J., Anderson, R. P., Purcell, A. W., Tye-Din, J. A., Koning, F., Reid, H. H. & Rossjohn, J., Jan 2020, In : Nature Structural and Molecular Biology. 27, p. 49-61 13 p.Research output: Contribution to journal › Article › Research › peer-review
1
Citation
(Scopus)
T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide
Tynan, F. E., Burrows, S. R., Buckle, A. M., Clements, C. S., Borg, N. A., Miles, J. J., Beddoe, T. C., Whisstock, J. C., Wilce, M. C. J., Silins, S. L., Burrows, J. M., Kjer-Nielsen, L., Kostenko, L., Purcell, A. W., McCluskey, J. & Rossjohn, J., 2005, In : Nature Immunology. 6, 11, p. 1114 - 1122 9 p.Research output: Contribution to journal › Article › Research › peer-review
214
Citations
(Scopus)
T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex
Beringer, D. X., Kleijwegt, F. S., Wiede, F., Van Der Slik, A. R., Loh, K. K. L., Petersen, J., Dudek, N. L., Duinkerken, G., Laban, S., Joosten, A. M., Vivian, J. P., Chen, Z., Uldrich, A. P., Godfrey, D. I., McCluskey, J., Price, D. A., Radford, K. J., Purcell, A. W., Nikolic, T., Reid, H. H. & 3 others, , 2015, In : Nature Immunology. 16, 11, p. 1153 - 1161 9 p.Research output: Contribution to journal › Article › Research › peer-review
63
Citations
(Scopus)
T-cells behaving badly: Structural insights into alloreactivity and autoimmunity
Ely, L. K., Burrows, S. R., Purcell, A. W., Rossjohn, J. & McCluskey, J., 2008, In : Current Opinion in Immunology. 20, 5, p. 575 - 580 6 p.Research output: Contribution to journal › Article › Research › peer-review
27
Citations
(Scopus)
Tentacle Transcriptomes of the Speckled Anemone (Actiniaria: Actiniidae: Oulactis sp.): Venom-Related Components and Their Domain Structure
Mitchell, M. L., Tonkin-Hill, G. Q., Morales, R. A. V., Purcell, A. W., Papenfuss, A. T. & Norton, R. S., 24 Jan 2020, (Accepted/In press) In : Marine Biotechnology. 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
The 1.5 Å crystal structure of a highly selected antiviral T cell receptor provides evidence for a structural basis of immunodominance
Kjer-Nielsen, L., Clements, C. S., Brooks, A. G., Purcell, A. W., McCluskey, J. & Rossjohn, J., 1 Nov 2002, In : Structure. 10, 11, p. 1521-1532 12 p.Research output: Contribution to journal › Article › Research › peer-review
59
Citations
(Scopus)
The 1.5 Crystal Structure of a Highly Selected Antiviral T Cell Receptor Provides Evidence for a Structural Basis of Immonodominance
Kjer-Nielsen, L., Clements, C. S., Brooks, A. G., Purcell, A. W., McClusky, J. & Rossjohn, J., 2002, In : Structure. 10, 11, p. 1521 - 1532 12 p.Research output: Contribution to journal › Article › Research › peer-review
The accessibility of the prosthetic group biotin during monomeric avidin affinity chromatography
Purcell, A. W. & Wallace, J. C., 1 Jan 1996, In : Analytical Biochemistry. 238, 2, p. 213-216 4 p.Research output: Contribution to journal › Article › Research › peer-review
5
Citations
(Scopus)
The A-chain of insulin is a hot-spot for CD4 + T cell epitopes in human type 1 diabetes
Mannering, S. I., Pang, S. H., Williamson, N. A., Naselli, G., Reynolds, E. C., O'Brien-Simpson, N. M., Purcell, A. W. & Harrison, L. C., May 2009, In : Clinical and Experimental Immunology. 156, 2, p. 226-231 6 p.Research output: Contribution to journal › Article › Other › peer-review
32
Citations
(Scopus)
The beta cell immunopeptidome
Dudek, N. L. & Purcell, A. W., 2014, In : Vitamins and Hormones-Advances in Research and Applications. 95, p. 115 - 144 30 p.Research output: Contribution to journal › Article › Research › peer-review
5
Citations
(Scopus)
The CDR3 regions of an Immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition
Borg, N. A., Ely, L. K., Beddoe, T. C., Macdonald, W. A., Reid, H. H., Clements, C. S., Purcell, A. W., Kjer-Nielsen, L., Miles, J. J., Burrows, S. R., McCluskey, J. & Rossjohn, J., 2005, In : Nature Immunology. 6, 2, p. 171 - 180 10 p.Research output: Contribution to journal › Article › Research › peer-review
137
Citations
(Scopus)
The cellular redox environment alters antigen presentation
Trujillo, J. A., Croft, N. P., Dudek, N. L., Channappanavar, R., Theodossis, A., Webb, A. I., Dunstone, M. A., Illing, P. TT., Butler, N. S., Fett, C., Tscharke, D. C., Rossjohn, J., Perlman, S. & Purcell, A. W., 2014, In : Journal of Biological Chemistry. 289, 40, p. 27979 - 27991 13 p.Research output: Contribution to journal › Article › Research › peer-review
15
Citations
(Scopus)
The central role played by peptides in the immune response and the design of peptide-based vaccines against infectious diseases and cancer
Jackson, D. C., Purcell, A. W., Fitzmaurice, C. J., Zeng, W. & Hart, D. N. J., 1 Jan 2002, In : Current Drug Targets. 3, 2, p. 175-196 22 p.Research output: Contribution to journal › Article › Research › peer-review
37
Citations
(Scopus)
The enantioselective total synthesis and unambiguous proof of the absolute stereochemistry of pervilleine C
Kulkarni, K. P., Zhao, A. Y., Purcell, A. W. & Perlmutter, P., 2008, In : Synlett. 2008, 14, p. 2209 - 2212 4 p.Research output: Contribution to journal › Article › Research › peer-review
10
Citations
(Scopus)