Projects per year
Personal profile
Biography
Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (5), Nature Immunol (9), Science Immunology, Nat Struc Mol Biol (2), Nature Comunications (5), PNAS (14), J Exp Med (8), Immunity (8), Nature Protocols, Mol Cell Proteomics (5), Proteomics (7) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Councillor Human Proteome Organisation, HuPO
1 Jan 2017 → 31 Dec 2023
Visiting Professor, University of Southampton
1 Jan 2016 → 31 Dec 2019
Research area keywords
- immunology and inflammation
- Mass Spectrometry
- Autoimmunity
- Cancer And Immunity
- Bioinformatics
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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An integrated approach to antigen discovery in autoimmunity and cancer
1/01/23 → 31/12/27
Project: Research
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Determination of “actionable vaccine targets” for breast cancer immunotherapy
Faridi, P., Dolcetti, R., Purcell, A., Mazzieri, R. & Southey, M.
1/01/23 → 31/12/26
Project: Research
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En route to identifying peptide antigen triggers in psoriasis.
Braun, A., Purcell, A. & Kern, J.
1/01/23 → 31/12/25
Project: Research
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Uncovering the pathway between gluten immunity and adverse symptoms in coeliac disease and gluten sensitivity to define novel treatments and symptom biomarkers
Hardy, M. Y., Martin, A. M., Ramarathinam, S., Tye-Din, J. A., Keating, D. J., Purcell, A. & Bampton, P.
1/03/22 → 1/03/26
Project: Research
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Immunolyser: A web-based computational pipeline for analysing and mining immunopeptidomic data
Munday, P. R., Fehring, J., Revote, J., Pandey, K., Shahbazy, M., Scull, K. E., Ramarathinam, S. H., Faridi, P., Croft, N. P., Braun, A., Li, C. & Purcell, A. W., Jan 2023, In: Computational and Structural Biotechnology Journal. 21, p. 1678-1687 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
TCR_Explore: A novel webtool for T cell receptor repertoire analysis
Mullan, K. A., Zhang, J. B., Jones, C. M., Goh, S. J. R., Revote, J., Illing, P. T., Purcell, A. W., La Gruta, N. L., Li, C. & Mifsud, N. A., Jan 2023, In: Computational and Structural Biotechnology Journal. 21, p. 1272-1282 11 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Defective Proinsulin Handling Modulates the MHC I Bound Peptidome and Activates the Inflammasome in β-Cells
Khilji, M. S., Faridi, P., Pinheiro-Machado, E., Hoefner, C., Dahlby, T., Aranha, R., Buus, S., Nielsen, M., Klusek, J., Mandrup-Poulsen, T., Purcell, A. W. & Marzec, M. T., Apr 2022, In: Biomedicines. 10, 4, 19 p., 814.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
HLA-A∗11:01-restricted CD8+ T cell immunity against influenza A and influenza B viruses in Indigenous and non-Indigenous people
Habel, J. R., Nguyen, A. T., Rowntree, L. C., Szeto, C., Mifsud, N. A., Clemens, E. B., Loh, L., Chen, W., Rockman, S., Nelson, J., Davies, J., Miller, A., Tong, S. Y. C., Rossjohn, J., Gras, S., Purcell, A. W., Hensen, L., Kedzierska, K. & Illing, P. T., Mar 2022, In: PLoS Pathogens. 18, 3, 28 p., e1010337.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
MhcVizPipe: A Quality Control Software for Rapid Assessment of Small- To Large-Scale Immunopeptidome Datasets
Kovalchik, K. A., Ma, Q., Wessling, L., Saab, F., Duquette, J. D., Kubiniok, P., Hamelin, D. J., Faridi, P., Li, C., Purcell, A. W., Jang, A., Paramithiotis, E., Tognetti, M., Reiter, L., Bruderer, R., Lanoix, J., Bonneil, É., Courcelles, M., Thibault, P., Caron, E., & 1 others, Jan 2022, In: Molecular & Cellular Proteomics. 21, 1, 15 p., 100178.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus)
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Molecular Immunology (Journal)
Anthony Purcell (Associate editor)
1 Oct 2019 → 30 Sep 2022Activity: Publication peer-review and editorial work types › Editorial responsibility
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Biochemistry & Molecular Biology (Organisational unit)
Anthony Purcell (Member), Steve Quenette (Member), Craig Paul Bonnington (Member), Stephen Tate (Member), Nick Koletsas (Member) & Nathan Paul Croft (Member)
1 Apr 2018 → 31 Dec 2020Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network
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Molecular & Cellular Proteomics (Journal)
Anthony Purcell (Editorial board member)
1 Jan 2016 → 31 Dec 2025Activity: Publication peer-review and editorial work types › Editorial responsibility
Press/Media
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A$9.8 million fight against superbugs
Jian Li, William Neil Charman, Jiangning Song, Anthony Wayne Purcell, Paul John Hertzog, Darren John Creek, Roger Leigh Nation, Jurgen Bullita & John Dallas Boyce
24/04/14
1 Media contribution
Press/Media: Public Engagement Activities