Projects per year
Personal profile
Biography
Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (5), Nature Immunol (9), Science Immunology, Nat Struc Mol Biol (2), Nature Comunications (5), PNAS (14), J Exp Med (8), Immunity (8), Nature Protocols, Mol Cell Proteomics (5), Proteomics (7) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Councillor Human Proteome Organisation, Human Proteome Organization
1 Jan 2017 → 31 Dec 2023
Visiting Professor, University of Southampton
1 Jan 2016 → 31 Dec 2019
Research area keywords
- immunology and inflammation
- Mass Spectrometry
- Autoimmunity
- Cancer And Immunity
- Bioinformatics
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Non-canonical antigen sources for cross-strain protective influenza immunity
Illing, P. (Primary Chief Investigator (PCI)), Braun, A. (Chief Investigator (CI)), Lahoud, M. (Associate Investigator (AI)), O'Keeffe, M. (Associate Investigator (AI)), Kedzierska, K. (Associate Investigator (AI)), Purcell, A. (Associate Investigator (AI)) & Mifsud, N. (Associate Investigator (AI))
1/01/24 → 31/12/27
Project: Research
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The "dark immunopeptidome" as a source of CD8 T cell epitopes in type 1 diabetes
DiLorenzo, T. P. (Primary Chief Investigator (PCI)), Purcell, A. (Chief Investigator (CI)), Illing, P. (Chief Investigator (CI)), Li, C. (Chief Investigator (CI)), Nakayama, M. (Chief Investigator (CI)) & Kent, S. (Chief Investigator (CI))
1/02/23 → 31/01/26
Project: Research
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En route to identifying peptide antigen triggers in psoriasis.
Braun, A. (Primary Chief Investigator (PCI)), Purcell, A. (Chief Investigator (CI)) & Kern, J. (Chief Investigator (CI))
1/01/23 → 31/12/25
Project: Research
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Determination of “actionable vaccine targets” for breast cancer immunotherapy
Faridi, P. (Primary Chief Investigator (PCI)), Dolcetti, R. (Chief Investigator (CI)), Purcell, A. (Associate Investigator (AI)), Mazzieri, R. (Associate Investigator (AI)) & Southey, M. (Associate Investigator (AI))
1/01/23 → 31/12/26
Project: Research
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An integrated approach to antigen discovery in autoimmunity and cancer
Purcell, A. (Primary Chief Investigator (PCI))
1/01/23 → 31/12/27
Project: Research
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Correction to: π-HuB: the proteomic navigator of the human body (Nature, (2024), 636, 8042, (322-331), 10.1038/s41586-024-08280-5)
He, F., Aebersold, R., Baker, M. S., Bian, X., Bo, X., Chan, D. W., Chang, C., Chen, L., Chen, X., Chen, Y. J., Cheng, H., Collins, B. C., Corrales, F., Cox, J., E, W., Van Eyk, J. E., Fan, J., Faridi, P., Figeys, D. & Gao, G. F. & 86 others, , 16 Jan 2025, In: Nature. 637, 8046, p. E22 1 p.Research output: Contribution to journal › Comment / Debate › Other › peer-review
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A Simple and Rapid Protocol for the Isolation of Murine Bone Marrow Suitable for the Differentiation of Dendritic Cells
Song, R., Bafit, M., Tullett, K. M., Tan, P. S., Lahoud, M. H., O’Keeffe, M., Purcell, A. W. & Braun, A., Apr 2024, In: Methods and Protocols. 7, 2, 10 p., 20.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
A tactile approach to introduce the skin autoimmune disease psoriasis to the general public and the vision-impaired community
Song, R., Ye, J., Chung, S., Meyer, C. C., Déchelette, C., Purcell, A. W. & Braun, A., May 2024, In: Immunology and Cell Biology. 102, 5, p. 336-340 5 p.Research output: Contribution to journal › Article › Other › peer-review
Open Access2 Citations (Scopus) -
CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age
Menon, T. (Leading Author), Illing, P. T. (Leading Author), Chaurasia, P. (Leading Author), McQuilten, H. A., Shepherd, C., Rowntree, L. C., Petersen, J., Littler, D. R., Khuu, G., Huang, Z., Allen, L. F., Rockman, S., Crowe, J., Flanagan, K. L., Wakim, L. M., Nguyen, T. H. O., Mifsud, N. A., Rossjohn, J. (Leading Author), Purcell, A. W. (Leading Author) & van de Sandt, C. E. (Leading Author) & 1 others, , 29 Apr 2024, In: Nature Communications. 15, 1, 21 p., 3387.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus) -
Epitope-anchored contrastive transfer learning for paired CD8+ T cell receptor–antigen recognition
Zhang, Y., Wang, Z., Jiang, Y., Littler, D. R., Gerstein, M., Purcell, A. W., Rossjohn, J., Ou, H. Y. & Song, J., Nov 2024, In: Nature Machine Intelligence. 6, 11, p. 1344–1358 15 p.Research output: Contribution to journal › Article › Research › peer-review
5 Citations (Scopus)
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Molecular Immunology (Journal)
Purcell, A. (Associate editor)
1 Oct 2019 → 30 Sept 2022Activity: Publication peer-review and editorial work types › Editorial responsibility
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Biochemistry & Molecular Biology (Organisational unit)
Purcell, A. (Member), Quenette, S. (Member), Bonnington, C. P. (Member), Tate, S. (Member), Koletsas, N. (Member) & Croft, N. P. (Member)
1 Apr 2018 → 31 Dec 2020Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network
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Molecular & Cellular Proteomics (Journal)
Anthony Purcell (Editorial board member)
1 Jan 2016 → 31 Dec 2025Activity: Publication peer-review and editorial work types › Editorial responsibility
Press/Media
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A$9.8 million fight against superbugs
Li, J., Charman, W. N., Song, J., Purcell, A. W., Hertzog, P. J., Creek, D. J., Nation, R. L., Bullita, J. & Boyce, J. D.
24/04/14
1 Media contribution
Press/Media: Public Engagement Activities