Projects per year
Personal profile
Biography
Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (4), Nature Immunol (4), Nat Struc Mol Biol, PNAS (12), J Exp Med (8), Immunity (8), Mol Cell Proteomics (3), Proteomics (4) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.
External positions
Visiting Professor, University of Southampton
1 Jan 2016 → 31 Dec 2018Keywords
- immunology and inflammation
- Mass Spectrometry
- Autoimmunity
- Cancer And Immunity
- Bioinformatics
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2005 2022
Understanding the complexity of antigen presentation
National Health & Medical Research Council (NHMRC)
1/01/18 → 31/12/22
Project: Research
Generation of protective immunity against severe influenza disease in Indigenous Australians
Kedzierska, K., Tong, S. Y. C., Miller, A. G., Purcell, A. W. & Gras, S.
1/01/17 → 31/12/20
Project: Research
Optimizing Clinical use of polymyxin B: teaching an old drug to treat superbugs
Li, J., Nation, R. L. & Purcell, A. W.
National Institutes of Health (NIH US)
19/06/15 → 31/05/20
Project: Research
Recognition of virus-infected cells by T cells
Tscharke, D., La Gruta, N., Purcell, A. W. & Croft, N. P.
National Health & Medical Research Council (NHMRC)
1/01/15 → 31/12/19
Project: Research
Research Output 1998 2018
A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands
Faridi, P., Li, C., Ramarathinam, S. H., Vivian, J. P., Illing, P. T., Mifsud, N. A., Ayala, R., Song, J., Gearing, L. J., Hertzog, P. J., Ternette, N., Rossjohn, J., Croft, N. P. & Purcell, A. W., 12 Oct 2018, In : Science Immunology. 3, 28, 12 p., eaar3947.Research output: Contribution to journal › Article › Research › peer-review
HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome
Illing, P. T., Pymm, P., Croft, N. P., Hilton, H. G., Jojic, V., Han, A. S., Mendoza, J. L., Mifsud, N. A., Dudek, N. L., McCluskey, J., Parham, P., Rossjohn, J., Vivian, J. P. & Purcell, A. W., 8 Nov 2018, In : Nature Communications. 9, 1, 13 p., 4693.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Identification of native and posttranslationally modified HLA-B*57:01- restricted HIV envelope derived epitopes using immunoproteomics
Ramarathinam, S. H., Gras, S., Alcantara, S., Yeung, A. W. S., Mifsud, N. A., Sonza, S., Illing, P., Glaros, E. N., Center, R. J., Thomas, S. R., Kent, S. J., Ternette, N., Purcell, D. F. J., Rossjohn, J. & Purcell, A. W., Jun 2018, In : Proteomics. 18, 12, 11 p., 1700253.Research output: Contribution to journal › Article › Research › peer-review
Inability to detect cross-reactive memory T cells challenges the frequency of heterologous immunity among common viruses
Rowntree, L. C., Nguyen, T. H. O., Halim, H., Purcell, A. W., Rossjohn, J., Gras, S., Kotsimbos, T. C. & Mifsud, N. A., 15 Jun 2018, In : Journal of Immunology. 200, 12, p. 3993-4003 11 p.Research output: Contribution to journal › Article › Research › peer-review
In Immunopeptidomics We Need a Sniper Instead of a Shotgun
Faridi, P., Purcell, A. W. & Croft, N. P., 2018, (Accepted/In press) In : Proteomics. 4 p.Research output: Contribution to journal › Article › Other › peer-review
Activities 2018 2018
- 1 Membership of industry collaboration/ network
Biochemistry & Molecular Biology (Organisational unit)
Anthony Purcell (Member), Steve Quenette (Member), Craig Paul Bonnington (Member), Stephen Tate (Member), Nick Koletsas (Member), Nathan Paul Croft (Member)1 Apr 2018 → 31 Dec 2020
Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network
Press / Media
A$9.8 million fight against superbugs
Jian Li, William Neil Charman, Jiangning Song, Anthony Wayne Purcell, Paul John Hertzog, Darren John Creek, Roger Leigh Nation, Jurgen Bullita & John Dallas Boyce
24/04/14
1 media contribution
Press/Media: Public Engagement Activities