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Personal profile

Biography

Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (4), Nature Immunol (4), Nat Struc Mol Biol, PNAS (12), J Exp Med (8), Immunity (8), Mol Cell Proteomics (3), Proteomics (4) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.

External positions

Visiting Professor, University of Southampton

1 Jan 201631 Dec 2018

Keywords

  • immunology and inflammation
  • Mass Spectrometry
  • Autoimmunity
  • Cancer And Immunity
  • Bioinformatics

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Projects 2005 2022

Research Output 1989 2019

Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates

Sun, Y., Kakinen, A., Xing, Y., Faridi, P., Nandakumar, A., Purcell, A. W., Davis, T. P., Ke, P. C. & Ding, F., 2019, (Accepted/In press) In : Small. 10 p., 1805166.

Research output: Contribution to journalArticleResearchpeer-review

Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

HLA-associated antiepileptic drug-induced cutaneous adverse reactions

Mullan, K. A., Anderson, A., Illing, P. T., Kwan, P., Purcell, A. W. & Mifsud, N. A., Jun 2019, In : HLA. 93, 6, p. 417-435 19 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Human CD8 + T cell cross-reactivity across influenza A, B and C viruses

Koutsakos, M., Illing, P. T., Nguyen, T. H. O., Mifsud, N. A., Crawford, J. C., Rizzetto, S., Eltahla, A. A., Clemens, E. B., Sant, S., Chua, B. Y., Wong, C. Y., Allen, E. K., Teng, D., Dash, P., Boyd, D. F., Grzelak, L., Zeng, W., Hurt, A. C., Barr, I., Rockman, S. & 17 othersJackson, D. C., Kotsimbos, T. C., Cheng, A. C., Richards, M., Westall, G. P., Loudovaris, T., Mannering, S. I., Elliott, M., Tangye, S. G., Wakim, L. M., Rossjohn, J., Vijaykrishna, D., Luciani, F., Thomas, P. G., Gras, S., Purcell, A. W. & Kedzierska, K., 18 Feb 2019, In : Nature Immunology. 20, p. 613-625 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Mass spectrometry–based identification of MHC-bound peptides for immunopeptidomics

Purcell, A. W., Ramarathinam, S. H. & Ternette, N., Jun 2019, In : Nature Protocols. 14, 21 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Activities 2018 2018

  • 1 Membership of industry collaboration/ network

Biochemistry & Molecular Biology (Organisational unit)

Anthony Purcell (Member), Steve Quenette (Member), Craig Paul Bonnington (Member), Stephen Tate (Member), Nick Koletsas (Member), Nathan Paul Croft (Member)
1 Apr 201831 Dec 2020

Activity: Industry, Government and Philanthropy Engagement and PartnershipsMembership of industry collaboration/ network

Press / Media

A$9.8 million fight against superbugs

Jian Li, William Charman, Jiangning Song, Anthony Purcell, Paul Hertzog, Darren Creek, Roger Nation, Jurgen Bullita & John Boyce

24/04/14

1 media contribution

Press/Media: Public Engagement Activities