Projects per year
Personal profile
Biography
Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (4), Nature Immunol (4), Nat Struc Mol Biol, PNAS (12), J Exp Med (8), Immunity (8), Mol Cell Proteomics (3), Proteomics (4) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.
External positions
Visiting Professor, University of Southampton
1 Jan 2016 → 31 Dec 2018Keywords
- immunology and inflammation
- Mass Spectrometry
- Autoimmunity
- Cancer And Immunity
- Bioinformatics
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2005 2022
Antigen presentation in cancer: new tools for the selection and prediction of cancer immunotherapy targets
Purcell, A. & Passantino, E.
1/02/19 → 31/07/22
Project: Research
Diversification of immune responses through unanticipated proteolytic mechanisms
1/01/19 → 31/12/21
Project: Research
Understanding the complexity of antigen presentation
National Health & Medical Research Council (NHMRC)
1/01/18 → 31/12/22
Project: Research
Optimizing Clinical use of polymyxin B: teaching an old drug to treat superbugs
Li, J., Nation, R. & Purcell, A.
National Institutes of Health (NIH US)
19/06/15 → 31/05/20
Project: Research
Recognition of virus-infected cells by T cells
Tscharke, D., La Gruta, N., Purcell, A. & Croft, N.
National Health & Medical Research Council (NHMRC)
1/01/15 → 31/12/19
Project: Research
Research Output 1998 2019
Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates
Sun, Y., Kakinen, A., Xing, Y., Faridi, P., Nandakumar, A., Purcell, A. W., Davis, T. P., Ke, P. C. & Ding, F., 2019, (Accepted/In press) In : Small. 10 p., 1805166.Research output: Contribution to journal › Article › Research › peer-review
Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa
Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Human CD8 + T cell cross-reactivity across influenza A, B and C viruses
Koutsakos, M., Illing, P. T., Nguyen, T. H. O., Mifsud, N. A., Crawford, J. C., Rizzetto, S., Eltahla, A. A., Clemens, E. B., Sant, S., Chua, B. Y., Wong, C. Y., Allen, E. K., Teng, D., Dash, P., Boyd, D. F., Grzelak, L., Zeng, W., Hurt, A. C., Barr, I., Rockman, S. & 17 others, 2019, (Accepted/In press) In : Nature Immunology. 15 p.Research output: Contribution to journal › Article › Research › peer-review
Most viral peptides displayed by class I MHC on infected cells are immunogenic
Croft, N. P., Smith, S. A., Pickering, J., Sidney, J., Peters, B., Faridi, P., Witney, M. J., Sebastian, P., Flesch, I. E. A., Heading, S. L., Sette, A., La Gruta, N. L., Purcell, A. W. & Tscharke, D. C., 19 Feb 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 8, p. 3112-3117 6 p.Research output: Contribution to journal › Article › Research › peer-review
Physical and toxicological profiles of human IAPP amyloids and plaques
Kakinen, A., Sun, Y., Javed, I., Faridi, A., Pilkington, E. H., Faridi, P., Purcell, A. W., Zhou, R., Ding, F., Lin, S., Ke, P. C. & Davis, T. P., 15 Jan 2019, In : Science Bulletin. 64, 1, p. 26-35 10 p.Research output: Contribution to journal › Article › Research › peer-review
Activities 2018 2018
- 1 Membership of industry collaboration/ network
Biochemistry & Molecular Biology (Organisational unit)
Anthony Purcell (Member), Steve Quenette (Member), Craig Paul Bonnington (Member), Stephen Tate (Member), Nick Koletsas (Member), Nathan Paul Croft (Member)1 Apr 2018 → 31 Dec 2020
Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network
Press / Media
A$9.8 million fight against superbugs
Jian Li, William Charman, Jiangning Song, Anthony Purcell, Paul Hertzog, Darren Creek, Roger Nation, Jurgen Bullita & John Boyce
24/04/14
1 media contribution
Press/Media: Public Engagement Activities