Anthony Purcell public CV

Anthony Purcell

Professor

Professor (Research), Biochemistry & Molecular Biology
Monash Biomedicine Discovery Institute

EmailAnthony.Purcell@monash.edu

Accepting PhD Students

PhD projects

Cancer Immunology Autoimmunity (Diabetes, arthritis, psoriasis, MS) Antigen processing and presentation Vaccine design Bioinformatics

Research activity per year

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Personal profile

Biography

Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (5), Nature Immunol (9), Science Immunology, Nat Struc Mol Biol (2), Nature Comunications (5), PNAS (14), J Exp Med (8), Immunity (8), Nature Protocols, Mol Cell Proteomics (5), Proteomics (7) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.

External positions

Associate Editor, Molecular Immunology (Elsevier)

1 Oct 2019 → 30 Sep 2022

Councillor Human Proteome Organisation, HuPO

1 Jan 2017 → 31 Dec 2023

Editorial Board Member, Molecular and Cellular Proteomics

1 Jan 2016 → 31 Dec 2025

Visiting Professor, University of Southampton

1 Jan 2016 → 31 Dec 2019

Research area keywords

immunology and inflammation
Mass Spectrometry
Autoimmunity
Cancer And Immunity
Bioinformatics

Network

Recent external collaboration on country level. Dive into details by clicking on the dots or

1 Curtailed
7 Active
22 Finished

Are hybrid peptide antigens pathogenic in rheumatoid arthritis?
Purcell, A.
1/01/21 → 31/12/21
Project: Research
Antigen discovery in Ewing Sarcoma
Purcell, A. & Faridi, P.
1/06/20 → 31/05/22
Project: Research
Designing Chimeric Antigen Receptor T cells for treating Diffuse Intrinsic Pontine Glioma
Jenkins, M., Purcell, A. & Hansford, J. R.
6/05/19 → 31/12/21
Project: Research
Antigen presentation in cancer: new tools for the selection and prediction of cancer immunotherapy targets
Passantino, E. & Purcell, A.
1/02/19 → 31/07/22
Project: Research
Diversification of immune responses through unanticipated proteolytic mechanisms
Purcell, A.
1/01/19 → 31/12/21
Project: Research

238 Article
17 Review Article
6 Chapter (Book)
5 Abstract
More

A comprehensive review and performance evaluation of bioinformatics tools for HLA class I peptide-binding prediction
Mei, S., Li, F., Leier, A., Marquez-Lago, T. T., Giam, K., Croft, N. P., Akutsu, T., Smith, A. I., Li, J., Rossjohn, J., Purcell, A. W. & Song, J., Jul 2020, In : Briefings in Bioinformatics. 21, 4, p. 1119-1135 17 p., bbz051.
Research output: Contribution to journal › Review Article › Research › peer-review

17 Citations (Scopus)
Acute experimental infection of bats and ferrets with Hendra virus: Insights into the early host response of the reservoir host and susceptible model species
Woon, A. P., Boyd, V., Todd, S., Smith, I., Klein, R., Woodhouse, I. B., Riddell, S., Crameri, G., Bingham, J., Wang, L. F., Purcell, A. W., Middleton, D. & Baker, M. L., 30 Mar 2020, In : PLoS Pathogens. 16, 3, 22 p., e1008412.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

1 Citation (Scopus)
A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver T_RM Cell-Mediated Immunity against Malaria in Mice
Valencia-Hernandez, A. M., Ng, W. Y., Ghazanfari, N., Ghilas, S., de Menezes, M. N., Holz, L. E., Huang, C., English, K., Naung, M., Tan, P. S., Tullett, K. M., Steiner, T. M., Enders, M. H., Beattie, L., Chua, Y. C., Jones, C. M., Cozijnsen, A., Mollard, V., Cai, Y., Bowen, D. G. & 15 others, Purcell, A. W., La Gruta, N. L., Villadangos, J. A., de Koning-Ward, T., Barry, A. E., Barchet, W., Cockburn, I. A., McFadden, G. I., Gras, S., Lahoud, M. H., Bertolino, P., Schittenhelm, R. B., Caminschi, I., Heath, W. R. & Fernandez-Ruiz, D., 10 Jun 2020, In : Cell Host & Microbe. 27, 6, p. 950-962 13 p.
Research output: Contribution to journal › Article › Research › peer-review

7 Citations (Scopus)
A shared TCR bias toward an immunogenic EBV epitope dominates in HLA-B*07: 02-Expressing individuals
Rowntree, L. C., Nguyen, T. H. O., Farenc, C., Halim, H., Hensen, L., Rossjohn, J., Kotsimbos, T. C., Purcell, A. W., Kedzierska, K., Gras, S. & Mifsud, N. A., 15 Sep 2020, In : Journal of Immunology. 205, 6, p. 1524-1534 11 p.
Research output: Contribution to journal › Article › Research › peer-review

1 Citation (Scopus)
Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system
Paul, S., Croft, N. P., Purcell, A. W., Tscharke, D. C., Sette, A., Nielsen, M. & Peters, B., 26 May 2020, In : PLoS Computational Biology. 16, 5, 18 p., e1007757.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
File

7 Citations (Scopus)

1 Membership of industry collaboration/ network

Biochemistry & Molecular Biology (Organisational unit)
Anthony Purcell (Member), Steve Quenette (Member), Craig Paul Bonnington (Member), Stephen Tate (Member), Nick Koletsas (Member) & Nathan Paul Croft (Member)
1 Apr 2018 → 31 Dec 2020
Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network

A$9.8 million fight against superbugs
Jian Li, William Neil Charman, Jiangning Song, Anthony Wayne Purcell, Paul John Hertzog, Darren John Creek, Roger Leigh Nation, Jurgen Bullita & John Dallas Boyce
24/04/14
1 Media contribution
Press/Media: Public Engagement Activities