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Personal profile

Biography

Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (4), Nature Immunol (4), Nat Struc Mol Biol, PNAS (12), J Exp Med (8), Immunity (8), Mol Cell Proteomics (3), Proteomics (4) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.

External positions

Visiting Professor, University of Southampton

1 Jan 201631 Dec 2018

Keywords

  • immunology and inflammation
  • Mass Spectrometry
  • Autoimmunity
  • Cancer And Immunity
  • Bioinformatics

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2005 2022

Research Output 1998 2018

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

Faridi, P., Li, C., Ramarathinam, S. H., Vivian, J. P., Illing, P. T., Mifsud, N. A., Ayala, R., Song, J., Gearing, L. J., Hertzog, P. J., Ternette, N., Rossjohn, J., Croft, N. P. & Purcell, A. W., 12 Oct 2018, In : Science Immunology. 3, 28, 12 p., eaar3947.

Research output: Contribution to journalArticleResearchpeer-review

Employing proteomics in the study of antigen presentation: an update

Ramarathinam, S. H., Croft, N. P., Illing, P. T., Faridi, P. & Purcell, A. W., 13 Aug 2018, In : Expert Review of Proteomics. 15, 8, p. 637-645 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome

Illing, P. T., Pymm, P., Croft, N. P., Hilton, H. G., Jojic, V., Han, A. S., Mendoza, J. L., Mifsud, N. A., Dudek, N. L., McCluskey, J., Parham, P., Rossjohn, J., Vivian, J. P. & Purcell, A. W., 8 Nov 2018, In : Nature Communications. 9, 1, 13 p., 4693.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Identification of native and posttranslationally modified HLA-B*57:01- restricted HIV envelope derived epitopes using immunoproteomics

Ramarathinam, S. H., Gras, S., Alcantara, S., Yeung, A. W. S., Mifsud, N. A., Sonza, S., Illing, P., Glaros, E. N., Center, R. J., Thomas, S. R., Kent, S. J., Ternette, N., Purcell, D. F. J., Rossjohn, J. & Purcell, A. W., Jun 2018, In : Proteomics. 18, 12, 11 p., 1700253.

Research output: Contribution to journalArticleResearchpeer-review

Immunopeptidomics Special Issue

Ternette, N. & Purcell, A. W., 1 Jun 2018, In : Proteomics. 18, 12, 4 p., 1800145.

Research output: Contribution to journalEditorialOtherpeer-review

Activities 2018 2018

  • 1 Membership of industry collaboration/ network

Biochemistry & Molecular Biology (Organisational unit)

Anthony Purcell (Member), Steve Quenette (Member), Craig Paul Bonnington (Member), Stephen Tate (Member), Nick Koletsas (Member), Nathan Paul Croft (Member)
1 Apr 201831 Dec 2020

Activity: Industry, Government and Philanthropy Engagement and PartnershipsMembership of industry collaboration/ network

Press / Media