Projects per year
Personal profile
Biography
Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (5), Nature Immunol (9), Science Immunology, Nat Struc Mol Biol (2), Nature Comunications (5), PNAS (14), J Exp Med (8), Immunity (8), Nature Protocols, Mol Cell Proteomics (5), Proteomics (7) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.
External positions
Associate Editor, Molecular Immunology (Elsevier)
1 Oct 2019 → 30 Sep 2022Councillor Human Proteome Organisation, HuPO
1 Jan 2017 → 31 Dec 2023Editorial Board Member, Molecular and Cellular Proteomics
1 Jan 2016 → 31 Dec 2025Visiting Professor, University of Southampton
1 Jan 2016 → 31 Dec 2019Research area keywords
- immunology and inflammation
- Mass Spectrometry
- Autoimmunity
- Cancer And Immunity
- Bioinformatics
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2005 2022
Dissecting the role of HLA-Cw6 for the presentation of antigens in Psoriasis
1/08/19 → 31/07/20
Project: Research
Identifying the source and nature of spliced and hybrid insulin peptides
1/07/19 → 30/06/20
Project: Research
Antigen presentation in cancer: new tools for the selection and prediction of cancer immunotherapy targets
Passantino, E. & Purcell, A.
1/02/19 → 31/07/22
Project: Research
Diversification of immune responses through unanticipated proteolytic mechanisms
1/01/19 → 31/12/21
Project: Research
Understanding the complexity of antigen presentation
National Health & Medical Research Council (NHMRC)
1/01/18 → 31/12/22
Project: Research
Research Output 1989 2020
Human Plasma Protein Corona of Aβ Amyloid and Its Impact on Islet Amyloid Polypeptide Cross-Seeding
Nandakumar, A., Xing, Y., Aranha, R. R., Faridi, A., Kakinen, A., Javed, I., Koppel, K., Pilkington, E. H., Purcell, A. W., Davis, T. P., Faridi, P., Ding, F. & Ke, P. C., 10 Feb 2020, In : Biomacromolecules. 21, 2, p. 988-998 11 p.Research output: Contribution to journal › Article › Research › peer-review
1
Citation
(Scopus)
T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease
Petersen, J., Ciacchi, L., Tran, M. T., Loh, K. L., Kooy-Winkelaar, Y., Croft, N. P., Hardy, M. Y., Chen, Z., McCluskey, J., Anderson, R. P., Purcell, A. W., Tye-Din, J. A., Koning, F., Reid, H. H. & Rossjohn, J., Jan 2020, In : Nature Structural and Molecular Biology. 27, p. 49-61 13 p.Research output: Contribution to journal › Article › Research › peer-review
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1
Le Nours, J., Gherardin, N. A., Ramarathinam, S. H., Awad, W., Wiede, F., Gully, B. S., Khandokar, Y., Praveena, T., Wubben, J. M., Sandow, J. J., Webb, A. I., von Borstel, A., Rice, M. T., Redmond, S. J., Seneviratna, R., Sandoval-Romero, M. L., Li, S., Souter, M. N. T., Eckle, S. B. G., Corbett, A. J. & 15 others, , 20 Dec 2019, In : Science. 366, 6472, p. 1522-1527 6 p.Research output: Contribution to journal › Article › Research › peer-review
A comprehensive review and performance evaluation of bioinformatics tools for HLA class I peptide-binding prediction
Mei, S., Li, F., Leier, A., Marquez-Lago, T. T., Giam, K., Croft, N. P., Akutsu, T., Smith, A. I., Li, J., Rossjohn, J., Purcell, A. W. & Song, J., 14 Jun 2019, (Accepted/In press) In : Briefings in Bioinformatics. 17 p., bbz051.Research output: Contribution to journal › Review Article › Research › peer-review
Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation
Lim Kam Sian, T. C. C., Indumathy, S., Halim, H., Greule, A., Cryle, M. J., Bowness, P., Rossjohn, J., Gras, S., Purcell, A. W. & Schittenhelm, R. B., 27 Dec 2019, In : Journal of Biological Chemistry. 294, 52, p. 20185-20195 11 p.Research output: Contribution to journal › Article › Research › peer-review
Activities 2018 2018
- 1 Membership of industry collaboration/ network
Biochemistry & Molecular Biology (Organisational unit)
Anthony Purcell (Member), Steve Quenette (Member), Craig Paul Bonnington (Member), Stephen Tate (Member), Nick Koletsas (Member), Nathan Paul Croft (Member)1 Apr 2018 → 31 Dec 2020
Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network
Press / Media
A$9.8 million fight against superbugs
Jian Li, William Neil Charman, Jiangning Song, Anthony Wayne Purcell, Paul John Hertzog, Darren John Creek, Roger Leigh Nation, Jurgen Bullita & John Dallas Boyce
24/04/14
1 Media contribution
Press/Media: Public Engagement Activities