Projects per year
Personal profile
Biography
Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (5), Nature Immunol (9), Science Immunology, Nat Struc Mol Biol (2), Nature Comunications (5), PNAS (14), J Exp Med (8), Immunity (8), Nature Protocols, Mol Cell Proteomics (5), Proteomics (7) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Councillor Human Proteome Organisation, HuPO
1 Jan 2017 → 31 Dec 2023
Visiting Professor, University of Southampton
1 Jan 2016 → 31 Dec 2019
Research area keywords
- immunology and inflammation
- Mass Spectrometry
- Autoimmunity
- Cancer And Immunity
- Bioinformatics
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Dominant classes of tumour specific antigens in Melanoma
Purcell, A., Faridi, P., Shackleton, M., Linette, G. & Behren, A.
1/01/22 → 31/12/24
Project: Research
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Exploring spliced MHC peptides in the context of a mouse model system
1/11/21 → 31/05/22
Project: Research
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Parallel Extended HDX system (Trajan Scientific and Medical)
Schittenhelm, R., Davidovich, C., Purcell, A., Ellisdon, A., Li, J., Aguilar, M., Cryle, M., Stone, M., Lithgow, T. & Zhang, Q.
1/10/21 → 31/12/22
Project: Research
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Validation of peptide antigen triggers in psoriasis patients - a step towards novel tolerization strategies
Braun, A., Purcell, A., Kern, J. & Varigos, G. A.
1/08/21 → 31/07/22
Project: Research
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MhcVizPipe: A Quality Control Software for Rapid Assessment of Small- To Large-Scale Immunopeptidome Datasets
Kovalchik, K. A., Ma, Q., Wessling, L., Saab, F., Duquette, J. D., Kubiniok, P., Hamelin, D. J., Faridi, P., Li, C., Purcell, A. W., Jang, A., Paramithiotis, E., Tognetti, M., Reiter, L., Bruderer, R., Lanoix, J., Bonneil, É., Courcelles, M., Thibault, P., Caron, E. & 1 others, , Jan 2022, In: Molecular & Cellular Proteomics. 21, 1, 15 p., 100178.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Anthem: a user customised tool for fast and accurate prediction of binding between peptides and HLA class I molecules
Mei, S., Li, F., Xiang, D., Ayala, R., Faridi, P., Webb, G. I., Illing, P. T., Rossjohn, J., Akutsu, T., Croft, N. P., Purcell, A. W. & Song, J., Sep 2021, In: Briefings in Bioinformatics. 22, 5, p. 1-16 16 p., bbaa415.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus) -
Carbamazepine Induces Focused T Cell Responses in Resolved Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Cases But Does Not Perturb the Immunopeptidome for T Cell Recognition
Mifsud, N. A., Illing, P. T., Lai, J. W., Fettke, H., Hensen, L., Huang, Z., Rossjohn, J., Vivian, J. P., Kwan, P. & Purcell, A. W., 12 Apr 2021, In: Frontiers in Immunology. 12, 20 p., 653710.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
Hensen, L., Illing, P. T., Bridie Clemens, E., Nguyen, T. H. O., Koutsakos, M., van de Sandt, C. E., Mifsud, N. A., Nguyen, A. T., Szeto, C., Chua, B. Y., Halim, H., Rizzetto, S., Luciani, F., Loh, L., Grant, E. J., Saunders, P. M., Brooks, A. G., Rockman, S., Kotsimbos, T. C., Cheng, A. C. & 16 others, , 18 May 2021, In: Nature Communications. 12, 1, 20 p., 2931.Research output: Contribution to journal › Article › Research › peer-review
Open Access3 Citations (Scopus) -
ggVolcanoR: A Shiny app for customizable visualization of differential expression datasets
Mullan, K. A., Bramberger, L. M., Munday, P. R., Goncalves, G., Revote, J., Mifsud, N. A., Illing, P. T., Anderson, A., Kwan, P., Purcell, A. W. & Li, C., Jan 2021, In: Computational and Structural Biotechnology Journal. 19, p. 5735-5740 6 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
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Molecular Immunology (Journal)
Anthony Purcell (Associate editor)
1 Oct 2019 → 30 Sep 2022Activity: Publication peer-review and editorial work types › Editorial responsibility
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Biochemistry & Molecular Biology (Organisational unit)
Anthony Purcell (Member), Steve Quenette (Member), Craig Paul Bonnington (Member), Stephen Tate (Member), Nick Koletsas (Member) & Nathan Paul Croft (Member)
1 Apr 2018 → 31 Dec 2020Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network
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Molecular & Cellular Proteomics (Journal)
Anthony Purcell (Editorial board member)
1 Jan 2016 → 31 Dec 2025Activity: Publication peer-review and editorial work types › Editorial responsibility
Press / Media
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A$9.8 million fight against superbugs
Jian Li, William Neil Charman, Jiangning Song, Anthony Wayne Purcell, Paul John Hertzog, Darren John Creek, Roger Leigh Nation, Jurgen Bullita & John Dallas Boyce
24/04/14
1 Media contribution
Press/Media: Public Engagement Activities