Projects per year
Personal profile
Biography
Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (5), Nature Immunol (9), Science Immunology, Nat Struc Mol Biol (2), Nature Comunications (5), PNAS (14), J Exp Med (8), Immunity (8), Nature Protocols, Mol Cell Proteomics (5), Proteomics (7) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.
External positions
Associate Editor, Molecular Immunology (Elsevier)
1 Oct 2019 → 30 Sep 2022Councillor Human Proteome Organisation, HuPO
1 Jan 2017 → 31 Dec 2023Editorial Board Member, Molecular and Cellular Proteomics
1 Jan 2016 → 31 Dec 2025Visiting Professor, University of Southampton
1 Jan 2016 → 31 Dec 2019Research area keywords
- immunology and inflammation
- Mass Spectrometry
- Autoimmunity
- Cancer And Immunity
- Bioinformatics
Network
Projects
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Designing Chimeric Antigen Receptor T cells for treating Diffuse Intrinsic Pontine Glioma
Jenkins, M., Purcell, A. & Hansford, J. R.
6/05/19 → 31/12/21
Project: Research
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Antigen presentation in cancer: new tools for the selection and prediction of cancer immunotherapy targets
Passantino, E. & Purcell, A.
1/02/19 → 31/07/22
Project: Research
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Diversification of immune responses through unanticipated proteolytic mechanisms
1/01/19 → 31/12/21
Project: Research
Research output
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A comprehensive review and performance evaluation of bioinformatics tools for HLA class I peptide-binding prediction
Mei, S., Li, F., Leier, A., Marquez-Lago, T. T., Giam, K., Croft, N. P., Akutsu, T., Smith, A. I., Li, J., Rossjohn, J., Purcell, A. W. & Song, J., Jul 2020, In : Briefings in Bioinformatics. 21, 4, p. 1119-1135 17 p., bbz051.Research output: Contribution to journal › Review Article › Research › peer-review
17 Citations (Scopus) -
Acute experimental infection of bats and ferrets with Hendra virus: Insights into the early host response of the reservoir host and susceptible model species
Woon, A. P., Boyd, V., Todd, S., Smith, I., Klein, R., Woodhouse, I. B., Riddell, S., Crameri, G., Bingham, J., Wang, L. F., Purcell, A. W., Middleton, D. & Baker, M. L., 30 Mar 2020, In : PLoS Pathogens. 16, 3, 22 p., e1008412.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile1 Citation (Scopus) -
A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice
Valencia-Hernandez, A. M., Ng, W. Y., Ghazanfari, N., Ghilas, S., de Menezes, M. N., Holz, L. E., Huang, C., English, K., Naung, M., Tan, P. S., Tullett, K. M., Steiner, T. M., Enders, M. H., Beattie, L., Chua, Y. C., Jones, C. M., Cozijnsen, A., Mollard, V., Cai, Y., Bowen, D. G. & 15 others, , 10 Jun 2020, In : Cell Host & Microbe. 27, 6, p. 950-962 13 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus) -
A shared TCR bias toward an immunogenic EBV epitope dominates in HLA-B*07: 02-Expressing individuals
Rowntree, L. C., Nguyen, T. H. O., Farenc, C., Halim, H., Hensen, L., Rossjohn, J., Kotsimbos, T. C., Purcell, A. W., Kedzierska, K., Gras, S. & Mifsud, N. A., 15 Sep 2020, In : Journal of Immunology. 205, 6, p. 1524-1534 11 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system
Paul, S., Croft, N. P., Purcell, A. W., Tscharke, D. C., Sette, A., Nielsen, M. & Peters, B., 26 May 2020, In : PLoS Computational Biology. 16, 5, 18 p., e1007757.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile7 Citations (Scopus)
Activities
- 1 Membership of industry collaboration/ network
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Biochemistry & Molecular Biology (Organisational unit)
Anthony Purcell (Member), Steve Quenette (Member), Craig Paul Bonnington (Member), Stephen Tate (Member), Nick Koletsas (Member) & Nathan Paul Croft (Member)
1 Apr 2018 → 31 Dec 2020Activity: Industry, Government and Philanthropy Engagement and Partnerships › Membership of industry collaboration/ network
Press / Media
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A$9.8 million fight against superbugs
Jian Li, William Neil Charman, Jiangning Song, Anthony Wayne Purcell, Paul John Hertzog, Darren John Creek, Roger Leigh Nation, Jurgen Bullita & John Dallas Boyce
24/04/14
1 Media contribution
Press/Media: Public Engagement Activities