Anthony Purcell

Professor

Professor (Research), Biochemistry & Molecular Biology
Monash Biomedicine Discovery Institute

https://orcid.org/0000-0003-0532-8331

EmailAnthony.Purcell@monash.edu

Accepting PhD Students

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Personal profile

Biography

Our laboratory specialises in targeted and global quantitative proteomics of complex biological samples, with a specific focus on identifying targets of the immune response and host-pathogen interactions. The laboratory has an outstanding track record in delivering high end outcomes including recent publications in highly regarding peer reviewed journals including Nature (4), Nature Immunol (4), Nat Struc Mol Biol, PNAS (12), J Exp Med (8), Immunity (8), Mol Cell Proteomics (3), Proteomics (4) and J Proteomics Res (3). We combine cutting edge proteomics with human immunology, molecular virology, structural and functional immunology to address a wide variety of immune questions.

External positions

Visiting Professor, University of Southampton

1 Jan 2016 → 31 Dec 2018

Keywords

immunology and inflammation
Mass Spectrometry
Autoimmunity
Cancer And Immunity
Bioinformatics

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Projects 2005 2022

1 Not started
5 Active
17 Finished

Antigen presentation in cancer: new tools for the selection and prediction of cancer immunotherapy targets

Purcell, A. & Passantino, E.

1/02/19 → 31/07/22

Project: Research

Diversification of immune responses through unanticipated proteolytic mechanisms

Purcell, A.

1/01/19 → 31/12/21

Project: Research

Understanding the complexity of antigen presentation

Purcell, A.

National Health & Medical Research Council (NHMRC)

1/01/18 → 31/12/22

Project: Research

Optimizing Clinical use of polymyxin B: teaching an old drug to treat superbugs

Li, J., Nation, R. & Purcell, A.

National Institutes of Health (NIH US)

19/06/15 → 31/05/20

Project: Research

Recognition of virus-infected cells by T cells

Tscharke, D., La Gruta, N., Purcell, A. & Croft, N.

National Health & Medical Research Council (NHMRC)

1/01/15 → 31/12/19

Project: Research

Research Output 1989 2019

216 Article
15 Review Article
6 Chapter (Book)
5 Abstract
10 More

Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates

Sun, Y., Kakinen, A., Xing, Y., Faridi, P., Nandakumar, A., Purcell, A. W., Davis, T. P., Ke, P. C. & Ding, F., 2019, (Accepted/In press) In : Small. 10 p., 1805166.

Research output: Contribution to journal › Article › Research › peer-review

Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

File

HLA-associated antiepileptic drug-induced cutaneous adverse reactions

Mullan, K. A., Anderson, A., Illing, P. T., Kwan, P., Purcell, A. W. & Mifsud, N. A., Jun 2019, In : HLA. 93, 6, p. 417-435 19 p.

Research output: Contribution to journal › Review Article › Research › peer-review

Human CD8 ⁺ T cell cross-reactivity across influenza A, B and C viruses

Koutsakos, M., Illing, P. T., Nguyen, T. H. O., Mifsud, N. A., Crawford, J. C., Rizzetto, S., Eltahla, A. A., Clemens, E. B., Sant, S., Chua, B. Y., Wong, C. Y., Allen, E. K., Teng, D., Dash, P., Boyd, D. F., Grzelak, L., Zeng, W., Hurt, A. C., Barr, I., Rockman, S. & 17 othersJackson, D. C., Kotsimbos, T. C., Cheng, A. C., Richards, M., Westall, G. P., Loudovaris, T., Mannering, S. I., Elliott, M., Tangye, S. G., Wakim, L. M., Rossjohn, J., Vijaykrishna, D., Luciani, F., Thomas, P. G., Gras, S., Purcell, A. W. & Kedzierska, K., 18 Feb 2019, In : Nature Immunology. 20, p. 613-625 15 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access

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