Projects per year
Personal profile
Research interests
The ECRU Translational Research Division laboratory is based at the Eastern Health Clinical School, Monash University Department of Medicine. Within the laboratory I supervise a research team involved in in vitro and in vivo evaluation of novel HDACi's and a number of other translational research projects. The research team consists of Dr Pavel Sluka together with past and present BSc (Hons) and PhD students. The laboratory is funded through competitive granting agencies together with pharmaceutical company research grants.
Biography
Associate Professor Dear completed his medical degree, with honours, at Monash University. He continued his clinical training at the Alfred and Box Hill Hospital campuses and currently holds an appointment at Eastern Health as a clinical consultant in Vascular Medicine. Associate Professor Dear obtained his PhD from Monash University for research examining the molecular biological control of components of the plasminogen activating system.
Associate Professor Dear heads the Eastern Clinical Research Unit (ECRU) Translational Research Division Laboratory at Monash University, Department of Medicine, Eastern Health Clinical School.
Associate Professor Dear is involved in numerous scientific collaborations with national and international research groups focusing on translational research programmes in several clinical disciplines.
See more detail of Anthony's research and team at:
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Neointimal Hyperplasia
- Cellular Biology
- Clinical Trial
- Demethylation Agents
- Diabetes
- Epigenetics
- Glucagon-Like
- Endothelial Cells
- Histone Deacetylase Inhibitors
- Light activated drugs
- Translational Research
- Vascular Biology
- Vascular Disease
- Drug eluting balloon
- Medical devices
Collaborations and top research areas from the last five years
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Development of a Novel Photo-Angioplasty Device for the Treatment of Occlusive Peripheral Vascular Disease
Dear, A., Fraser, J., Li Bassi, G., Thompson, P., Gaspari, T. & Thissen, H.
1/01/22 → 31/12/25
Project: Research
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An open-label, extension safety and efficacy study of Pregabalin In patients with Postherpetic Neuralgia
Bladin, C. & Dear, A.
1/06/02 → …
Project: Research
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Lead optimisation of novel inhibitors of IRAP for the treatment of fibrosis in diabetes-induced renal and cardiovascular disease
Gaspari, T., Chai, S., Widdop, R., Thompson, P., Nielsen, K., Perez, S., Dear, A., Yun, B., Pfleger, K. & Barlow, N.
1/10/21 → 30/11/23
Project: Research
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Equipment Grant - HistoIndex Genesis(R)200 Platform
Samuel, C., Widdop, R., Denton, K., Chin-Dusting, J., Aguilar, M., Wallace, E., Lim, R., Evans, R., Black, M., Ricardo, S., Sievert, W., Dear, A. & Kerr, P.
3/02/17 → 31/12/17
Project: Research
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Advances in Design and Development of Lumi-Solve: A Novel Drug-Eluting Photo-Angioplasty Device
Sangeetha Menon, A., Subasic de Azevedo, I., Choong, K., Bhatnagar, D., Wang, C., Sluka, P., Chisholm, D. R., Pasic, P., Thissen, H., Sama, G., Robinson, A., Rodda, A., Tria, A., Spiegel, L., Dharma, A., Kaipananickal, H., Okabe, J., El-Osta, A., Mountford, S., Thompson, P., & 1 others , Aug 2023, In: Cardiovascular Engineering and Technology. 14, p. 605–614 10 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Fibromuscular Dysplasia: Three Cases to Highlight a Requirement for Surveillance Strategy Optimization
Tran, A., Yii, E. & Dear, A. E., Dec 2023, In: Cureus. 15, 12, 2 p., e50802.Research output: Contribution to journal › Article › Other › peer-review
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A pilot clinical study to Evaluate Liraglutide-mediated Anti-platelet activity in patients with type-2 Diabetes (ELAID study)
Loganathan, J., Cohen, A. C., Kaloupis, G. M., Harris, C., Chronopoulos, A., James, V., Hamilton, J., Green, S., Wallis, A., Morgan, S., Dauer, R., Gilfillan, C. & Dear, A. E., May 2022, In: Journal of Diabetes and its Complications. 36, 5, 8 p., 108188.Research output: Contribution to journal › Article › Research › peer-review
6 Citations (Scopus) -
Point of care ankle pulse waveform: A biomarker for abdominal aortic aneurysm?
Tran, A., Pope, A. & Dear, A. E., Jun 2022, In: Vascular. 30, 3, p. 427-431 5 p.Research output: Contribution to journal › Article › Research › peer-review
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Design, Development, In Vitro and Preliminary In Vivo Evaluation of a Novel Photo-Angioplasty Device: Lumi-Solve
Liu, H., Sama, G. R., Robinson, A., Mountford, S., E. Thompson, P., Rodda, A., Forsythe, J., Mornane, P. J., Pasic, P., Thissen, H., Byrne, M., Kaye, D. M. & Dear, A. E., Aug 2021, In: Cardiovascular Engineering and Technology. 12, p. 466–473 8 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus)
Press/Media
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A Clinical Trial of a Novel Treatment for Abdominal Aortic Aneurysm
13/03/21
1 item of Media coverage
Press/Media: Profile/Interview
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A Clinical Trial to Evaluate a Novel Agent to Treat Abdominal Aortic Aneurysm
12/03/21
1 item of Media coverage
Press/Media: Profile/Interview
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New medical device may reduce risks in common medical procedure
15/12/19 → 3/03/21
2 Media contributions
Press/Media: Profile/Interview
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A New Glucose Regulating Drug to Reduce Potential Progression of Vascular Disease
23/09/13
1 Media contribution
Press/Media: Profile/Interview