Anouk von Borstel

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Anouk von Borstel

Dr

 https://orcid.org/0000-0002-3605-7936
20172023

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Personal profile

Biography

Dr. Anouk von Borstel is an early career researcher in the Immunology Department, with a keen interest in the adaptive immune system. She earned her PhD in 2019 from the Rijksuniversiteit Groningen, the Netherlands, where she investigated the role of B cells in rheumatic autoimmune diseases and published four first and corresponding author articles. In 2018, she was recruited to Monash University for her expertise in cellular immunology. Currently, Dr. von Borstel's research focuses on the immunobiology of antigen-specific immune cells, particularly in relation to allergy. Her goal is to understand the functions and transcriptional pathways that regulate these cells and how they protect against disease following immunotherapy. She possesses ample experience in immunological and molecular techniques such as flow cytometry, cell sorting, and (single cell) RNA sequencing, and she uses human immune cells (both circulating and tissue-infiltrating) from patients with autoimmunity, allergy, cancer, and infectious diseases. Dr. von Borstel’s exciting work has resulted in several lead and co-authorships on articles published in high-quality journals such as Science, Science Translational Medicine and Science Immunology.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

B cells in ANCA-associated vasculitis, PhD, Universitair Medisch Centrum Groningen (UMCG) (University Medical Center Groningen)

15 Aug 2015 → 31 Oct 2018

External positions

PhD Candidate, Universitair Medisch Centrum Groningen (UMCG) (University Medical Center Groningen)

15 Aug 2015 → 30 Nov 2018

Research area keywords

  • Human Immunology
  • gamma delta T cells
  • Immune Surveillance
  • Antigen-specific B cells
  • Allergy
  • Autoimmunity
  • Memory B cells

Collaborations and top research areas from the last five years

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  • Circulating effector γδ T cell populations are associated with acute coronavirus disease 19 in unvaccinated individuals

    von Borstel, A., Nguyen, T. H. O., Rowntree, L. C., Ashhurst, T. M., Allen, L. F., Howson, L. J., Holmes, N. E., Smibert, O. C., Trubiano, J. A., Gordon, C. L., Cheng, A. C., Kent, S. J., Rossjohn, J., Kedzierska, K. & Davey, M. S., Apr 2023, In: Immunology and Cell Biology. 101, 4, p. 321-332 12 p.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access

  • Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors

    Wegrecki, M., Ocampo, T. A., Gunasinghe, S. D., von Borstel, A., Tin, S. Y., Reijneveld, J. F., Cao, T-P., Gully, B. S., Le Nours, J., Moody, D. B., Van Rhijn, I. & Rossjohn, J., Dec 2022, In: Nature Communications. 13, 1, 15 p., 3872.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    10 Citations (Scopus)

  • Transcriptional profiling of human Vδ1 T cells reveals a pathogen-driven adaptive differentiation program

    McMurray, J. L., von Borstel, A., Taher, T. E., Syrimi, E., Taylor, G. S., Sharif, M., Rossjohn, J., Remmerswaal, E. B. M., Bemelman, F. J., Vieira Braga, F. A., Chen, X., Teichmann, S. A., Mohammed, F., Berry, A. A., Lyke, K. E., Williamson, K. C., Stubbington, M. J. T., Davey, M. S., Willcox, C. R. & Willcox, B. E., 24 May 2022, In: Cell Reports. 39, 8, 16 p., 110858.

    Research output: Contribution to journal › Article › Research › peer-review

    Open Access
    7 Citations (Scopus)

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

    Cossarizza, A., Chang, H. D., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., Bacher, P., Bari, S., Barnaba, V., Barros-Martins, J., Baumjohann, D., Beccaria, C. G., Bernardo, D., Boardman, D. A., Borger, J., Böttcher, C., & 173 othersBrockmann, L., Burns, M., Busch, D. H., Cameron, G., Cammarata, I., Cassotta, A., Chang, Y., Chirdo, F. G., Christakou, E., Čičin-Šain, L., Cook, L., Corbett, A. J., Cornelis, R., Cosmi, L., Davey, M. S., De Biasi, S., De Simone, G., del Zotto, G., Delacher, M., Di Rosa, F., Santo, J. D., Diefenbach, A., Dong, J., Dörner, T., Dress, R. J., Dutertre, C. A., Eckle, S. B. G., Eede, P., Evrard, M., Falk, C. S., Feuerer, M., Fillatreau, S., Fiz-Lopez, A., Follo, M., Foulds, G. A., Fröbel, J., Gagliani, N., Galletti, G., Gangaev, A., Garbi, N., Garrote, J. A., Geginat, J., Gherardin, N. A., Gibellini, L., Ginhoux, F., Godfrey, D. I., Gruarin, P., Haftmann, C., Hansmann, L., Harpur, C. M., Hayday, A. C., Heine, G., Hernández, D. C., Herrmann, M., Hoelsken, O., Huang, Q., Huber, S., Huber, J. E., Huehn, J., Hundemer, M., Hwang, W. Y. K., Iannacone, M., Ivison, S. M., Jäck, H. M., Jani, P. K., Keller, B., Kessler, N., Ketelaars, S., Knop, L., Knopf, J., Koay, H. F., Kobow, K., Kriegsmann, K., Kristyanto, H., Krueger, A., Kuehne, J. F., Kunze-Schumacher, H., Kvistborg, P., Kwok, I., Latorre, D., Lenz, D., Levings, M. K., Lino, A. C., Liotta, F., Long, H. M., Lugli, E., MacDonald, K. N., Maggi, L., Maini, M. K., Mair, F., Manta, C., Manz, R. A., Mashreghi, M. F., Mazzoni, A., McCluskey, J., Mei, H. E., Melchers, F., Melzer, S., Mielenz, D., Monin, L., Moretta, L., Multhoff, G., Muñoz, L. E., Muñoz-Ruiz, M., Muscate, F., Natalini, A., Neumann, K., Ng, L. G., Niedobitek, A., Niemz, J., Almeida, L. N., Notarbartolo, S., Ostendorf, L., Pallett, L. J., Patel, A. A., Percin, G. I., Peruzzi, G., Pinti, M., Pockley, A. G., Pracht, K., Prinz, I., Pujol-Autonell, I., Pulvirenti, N., Quatrini, L., Quinn, K. M., Radbruch, H., Rhys, H., Rodrigo, M. B., Romagnani, C., Saggau, C., Sakaguchi, S., Sallusto, F., Sanderink, L., Sandrock, I., Schauer, C., Scheffold, A., Scherer, H. U., Schiemann, M., Schildberg, F. A., Schober, K., Schoen, J., Schuh, W., Schüler, T., Schulz, A. R., Schulz, S., Schulze, J., Simonetti, S., Singh, J., Sitnik, K. M., Stark, R., Starossom, S., Stehle, C., Szelinski, F., Tan, L., Tarnok, A., Tornack, J., Tree, T. I. M., van Beek, J. J. P., van de Veen, W., van Gisbergen, K., Vasco, C., Verheyden, N. A., von Borstel, A., Ward-Hartstonge, K. A., Warnatz, K., Waskow, C., Wiedemann, A., Wilharm, A., Wing, J., Wirz, O., Wittner, J., Yang, J. H. M. & Yang, J., Dec 2021, In: European Journal of Immunology. 51, 12, p. 2708-3145 438 p.

    Research output: Contribution to journal › Article › Other › peer-review

    Open Access
    118 Citations (Scopus)

  • Mucosal-associated invariant T Cell effector function is an intrinsic cell property that can be augmented by the Metabolic Cofactor α-Ketoglutarate

    Howson, L. J., Li, J., von Borstel, A., Barugahare, A. A., Mak, J. Y. W., Fairlie, D. P., McCluskey, J., Turner, S. J., Davey, M. S. & Rossjohn, J., 1 Apr 2021, In: Journal of Immunology. 206, 7, p. 1425-1435 11 p.

    Research output: Contribution to journal › Article › Research › peer-review

    7 Citations (Scopus)
View all 17 research outputs
View all 6 prizes
View all 27 activities