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19992024

Research activity per year

Personal profile

Monash teaching commitment

BMS1062 Molecular Biology

BMS2062 Introduction to Bioinformatics (unit convenor and lecturer)

BCH3052 Advanced Protein Biology: from Sequence to Structure and Disease

MIC3032 Pathogenesis of Bacterial Infectious Diseases

Biography

A/Professor Anna Roujeinikova leads a research group at Monash University's Biomedicine Discovery Institute. Her research focuses on bacteria of medical importance. She received interdisciplinary education; she studied Natural Sciences (BSc cum laude) and Applied Physics and Mathematics (MSc with distinct.) at the Moscow Institute of Physics and Technology. She obtained a PhD in Structural Biology from the University of Sheffield (UK). Prior to joining Monash University (Australia) as an Associate Professor, Anna gained postdoctoral experience at the Institute for Cancer Studies (Sheffield, UK), Leicester University (UK) and Manchester University (UK). She has determined and published ~90 different crystal structures and her work has led to a significant advance of knowledge about human pathogens. For example, her work unravelling the molecular mechanism of action of a common antiseptic triclosan (Nature, 1999) provided evidence supporting the World Health Organisation Global Guidelines for the Prevention of Surgical Site Infection. Her subsequent work on essential bacterial proteins and mechanisms of their inhibition by commercial drugs has attracted significant interest from pharmaceutical companies, and the structures she published have subsequently been used as templates for the design of novel drug candidates for antibacterial, antiparasite and HIV treatment. More recently her main focus has been on bacterial motility and its control by chemoreceptors. Her group uses an interdisciplinary approach combining microbiology and physics to study the structure, function and regulation of the bacterial flagellar motor. Her achievements in this area have been recognised by the awards of Fellowships (a Wellcome Trust (UK) Career Development Fellowship (2006) and ARC Research Fellowship (2010)) and grants from ARC, NHMRC and NIH.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Research area keywords

  • bacterial flagellar motor
  • structural biology
  • Helicobacter pylori
  • crystallography
  • biocatalysis
  • bacterial chemotaxis
  • antibiotic resistance
  • molecular basis of disease
  • Campylobacter jejuni
  • protein biochemistry
  • biophysics
  • bacterial pathogenicity
  • membrane proteins
  • enzyme activity
  • protein-protein interactions
  • antimicrobials

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or