19972020

Research output per year

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Research Output

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Article
2020

Gelatin-based 3D microgels for in vitro T lineage cell generation

Suraiya, A. B., Hun, M. L., Truong, V. X., Forsythe, J. S. & Chidgey, A. P., 13 Apr 2020, In : ACS Biomaterials Science & Engineering. 6, 4, p. 2198-2208 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Gender Disparity Impacts on Thymus Aging and LHRH Receptor Antagonist-Induced Thymic Reconstitution Following Chemotherapeutic Damage

Hun, M. L., Wong, K., Gunawan, J. R., Alsharif, A. A. M., Quinn, K. & Chidgey, A. P., 3 Mar 2020, In : Frontiers in Immunology. 11, 20 p., 302.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids

Motazedian, A., Bruveris, F. F., Kumar, S. V., Schiesser, J. V., Chen, T., Ng, E. S., Chidgey, A. P., Wells, C. A., Elefanty, A. G. & Stanley, E. G., 6 Jan 2020, In : Nature Cell Biology. 22, 1, p. 60-73 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
2019

Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia

Hu, M., Eviston, D., Hsu, P., Mariño, E., Chidgey, A., Santner-Nanan, B., Wong, K., Richards, J. L., Yap, Y. A., Collier, F., Quinton, A., Joung, S., Peek, M., Benzie, R., Macia, L., Wilson, D., Ponsonby, A. L., Tang, M. L. K., O’Hely, M., Daly, N. L. & 5 others, Mackay, C. R., Dahlstrom, J. E., The BIS Investigator Group, Vuillermin, P. & Nanan, R., 10 Jul 2019, In : Nature Communications. 10, 1, 13 p., 3031.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging

Lepletier, A., Hun, M. L., Hammett, M. V., Wong, K., Naeem, H., Hedger, M., Loveland, K. & Chidgey, A. P., 25 Jun 2019, In : Cell Reports. 27, 13, p. 3887–3901–e4 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)
2018

Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice

O'Sullivan, B. J., Yekollu, S., Ruscher, R., Mehdi, A., Maradana, M. R., Chidgey, A. P. & Thomas, R., 22 May 2018, In : Frontiers in Immunology. 9, MAY, 11 p., 1092.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)
2017

A novel Foxn1eGFP/+ mouse model identifies Bmp4-induced maintenance of Foxn1 expression and thymic epithelial progenitor populations

Barsanti, M., Lim, J. M. C., Hun, M. L., Lister, N., Wong, K., Hammett, M. V., Lepletier, A., Boyd, R. L., Giudice, A. & Chidgey, A. P., Feb 2017, In : European Journal of Immunology. 47, 2, p. 291-304 14 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Native thymic extracellular matrix improves in vivo thymic organoid T cell output, and drives in vitro thymic epithelial cell differentiation

Hun, M., Barsanti, M., Wong, K., Ramshaw, J., Werkmeister, J. & Chidgey, A. P., Feb 2017, In : Biomaterials. 118, p. 1-15 15 p., 145253.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)
2016

In situ -forming click-crosslinked gelatin based hydrogels for 3D culture of thymic epithelial cells

Truong, V. X., Hun, M. L., Li, F., Chidgey, A. P. & Forsythe, J. S., 1 Jul 2016, In : Biomaterials Science. 4, 7, p. 1123-1131 9 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)
2015

Enhanced hematopoietic stem cell function mediates immune regeneration following sex steroid blockade

Khong, D. M., Dudakov, J. A., Hammett, M. V., Jurblum, M. I., Khong, S. M. L., Goldberg, G. L., Ueno, T., Spyroglou, L. G., Young, L. F., van den Brink, M. R. M., Boyd, R. L. & Chidgey, A. P., 2015, In : Stem Cell Reports. 4, 3, p. 445 - 458 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
13 Citations (Scopus)

New role for the (pro)renin receptor in T-cell development

Geisberger, S., Maschke, U., Gebhardt, M., Kleinewietfeld, M., Manzel, A., Linker, R. A., Chidgey, A. P., Dechend, R., Nguyen, G., Daumke, O., Muller, D. N., Wright, M. D. & Binger, K. J., 2015, In : Blood. 126, 4, p. 504 - 507 4 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Perspectives for improvement of the thymic microenvironment through manipulation of thymic epithelial cells: a mini-review

Lepletier, A., Chidgey, A. P. & Savino, W., 2015, In : Gerontology. 61, 6, p. 504-514 11 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)
2014

Establishment of transplantation tolerance via minimal conditioning in aged recipients

Morison, J. K., Homann, J., Hammett, M. V., Seach, N. L., Layton, D. S., Malin, M. A., Thorburn, A. N., Chidgey, A. P., Boyd, R. L. & Heng, T. S. P., 2014, In : American Journal of Transplantation. 14, 11, p. 2478 - 2490 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

FOXN1GFP/w reporter hESCs enable identification of integrin-a4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1 + thymic epithelial progenitors

Soh, C-L., Giudice, A., Jenny, R. A., Elliott, D. A., Hatzistavrou, T., Micallef, S. J., Kianizad, K., Seach, N. L., Zuniga-Pflucker, J. C., Chidgey, A. P., Trounson, A. O., Nilsson, S. S. K., Haylock, D. N., Boyd, R. L., Elefanty, A. G. & Stanley, E. G., 2014, In : Stem Cell Reports. 2, 6, p. 925 - 937 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)

Multilineage potential and self-renewal define an epithelial progenitor cell population in the adult thymus

Wong, K. Y. P., Seach, N. L., Barsanti, M., Lim, J. M. C., Hammett, M. V., Khong, D. M., Siatskas, C., Gray, D. H. D., Boyd, R. L. & Chidgey, A. P., 2014, In : Cell Reports. 8, 4, p. 1198 - 1209 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
79 Citations (Scopus)
2013

Isolation, characterization, and reaggregate culture of thymic epithelial cells

Seach, N. L., Hammett, M. V. & Chidgey, A. P., 2013, In : Methods in Molecular Biology. 945, p. 251 - 272 22 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

The role of Tenascin C in the lymphoid progenitor cell niche

Ellis, S. L., Heazlewood, S. Y., Williams, B., Reitsma, A. J., Grassinger, J., Borg, J., Heazlewood, C. K., Chidgey, A. P. & Nilsson, S. K., 2013, In : Experimental Hematology. 41, 12, p. 1050 - 1061 12 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Thymic deletion and regulatory T cells prevent antimyeloperoxidase GN

Tan, D. S. Y., Gan, P. Y., O'Sullivan, K., Hammett, M. V., Summers, S. A., Ooi, J., Lundgren, B. A., Boyd, R. L., Scott, H. S., Kitching, A. R., Chidgey, A. P. & Holdsworth, S. R., 2013, In : Journal of the American Society of Nephrology. 24, 4, p. 573 - 585 13 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)
2012

Purified enzymes improve isolation and characterization of the adult thymic epithelium

Seach, N. L., Wong, K., Hammett, M. V., Boyd, R. L. & Chidgey, A. P., 2012, In : Journal of Immunological Methods. 385, 1-2, p. 23 - 34 12 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)
2011

The contribution of thymic stromal abnormalities to autoimmune disease

Fletcher, A., Calder, A., Hince, M., Boyd, R. & Chidgey, A., 2011, In : Critical Reviews in Immunology. 31, 3, p. 171 - 187 17 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Thymic involution: Where endocrinology meets immunology

Calder, A., Hince, M., Dudakov, J., Chidgey, A. & Boyd, R., 2011, In : Neuroimmunomodulation. 18, 5, p. 281 - 289 9 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)
2010

Feeding the fire: the role of defective bone marrow function in exacerbating thymic involution

Dudakov, J. A., Khong, D. M. P., Boyd, R. L. & Chidgey, A. P., 2010, In : Trends in Immunology. 31, 5, p. 191 - 198 8 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Regeneration of dendritic cells in aged mice

van Dommelen, S. LH., Rizzitelli, A., Chidgey, A. P., Boyd, R. L., Shortman, K. & Wu, L., 2010, In : Cellular & Molecular Immunology. 7, 2, p. 108 - 115 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Sex steroid ablation enhances immune reconstitution following cytotoxic antineoplastic therapy in young mice

Goldberg, G. L., Dudakov, J. A., Reiseger, J. J., Seach, N. L., Ueno, T., Vlahos, K., Hammett, M. V., Young, L. F., Heng, T. S. P., Boyd, R. L. & Chidgey, A. P., 2010, In : Journal of Immunology. 184, 11, p. 6014 - 6024 11 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)
2009

Ablation and regeneration of tolerance-inducing medullary thymic epithelial cells after cyclosporine, cyclophosphamide, and dexamethasone treatment

Fletcher, A. L., Lowen, T. E., Sakkal, S., Reiseger, J. J., Hammett, M. V., Seach, N. L., Scott, H. S., Boyd, R. L. & Chidgey, A. P., 2009, In : Journal of Immunology. 183, 2, p. 823 - 831 9 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Androgen depletion increases the efficacy of bone marrow transplantation in ameliorating experimental autoimmune encephalomyelitis

Barnard, A. L., Chidgey, A. P., Bernard, C. C. A. & Boyd, R. L., 2009, In : Blood. 113, p. 204 - 213 9 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Characterization of the thymic IL-7 niche in vivo

Alves, N. L., Richard-Le Goff, O., Huntington, N. D., Sousa, A. P., Ribeiro, V. S. G., Bordack, A., Vives, F. L., Peduto, L., Chidgey, A. P., Cumano, A., Boyd, R. L., Eberl, G. & Di Santo, J. P., 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 5, p. 1512 - 1517 6 p.

Research output: Contribution to journalArticleResearchpeer-review

89 Citations (Scopus)

Luteinizing hormone-releasing hormone enhances T cell recovery following allogeneic bone marrow transplantation

Goldberg, G. L., King, C. G., Nejat, R. A., Suh, D. Y., Smith, O. M., Bretz, J. C., Samstein, R. M., Dudakov, J. A., Chidgey, A. P., Chen-Kiang, S., Boyd, R. L. & van den Brink, M. R. M., 2009, In : Journal of Immunology. 182, 9, p. 5846 - 5854 9 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

Sex steroid ablation enhances hematopoietic recovery following cytotoxic antineoplastic therapy in aged mice

Dudakov, J. A., Goldberg, G. L., Reiseger, J. J., Vlahos, K., Chidgey, A. P. & Boyd, R. L., 2009, In : Journal of Immunology. 183, 11, p. 7084 - 7094 11 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Thymic involution and immune reconstitution

Lynch, H. E., Goldberg, G. L., Chidgey, A. P., van den Brink, M. R. M., Boyd, R. L. & Sempowski, G. D., 2009, In : Trends in Immunology. 30, 7, p. 366 - 373 8 p.

Research output: Contribution to journalArticleResearchpeer-review

266 Citations (Scopus)

VEGF-mediated cross-talk within the neonatal murine thymus

Cuddihy, A. R., Ge, S., Zhu, J., Jang, J., Chidgey, A. P., Thurston, G., Boyd, R. L. & Crooks, G. M., 2009, In : Blood. 113, p. 2723 - 2731 8 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Withdrawal of sex steroids reverses age- and chemotherapy-related defects in bone marrow lymphopoiesis

Dudakov, J. A., Goldberg, G. L., Reiseger, J. J., Chidgey, A. P. & Boyd, R. L., 2009, In : Journal of Immunology. 182, 10, p. 6247 - 6260 14 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)
2008

Effects of growth hormone in enhancing thymic regrowth and T-cell reconstitution

Chidgey, A. P., 2008, In : Expert Review of Clinical Immunology. 4, 4, p. 433 - 439 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Enhanced immune system regeneration in humans following allogeneic or autologous hemopoietic stem cell transplantation by temporary sex steroid blockade

Sutherland, J. S., Spyroglou, L. G., Muirhead, J. L., Heng, T. S. P., Prieto-Hinojosa, A., Prince, H. M., Chidgey, A. P., Schwarer, A. P. & Boyd, R. L., 2008, In : Clinical Cancer Research. 14, 4, p. 1138 - 1149 12 p.

Research output: Contribution to journalArticleResearchpeer-review

78 Citations (Scopus)

Immune privilege for stem cells: Not as simple as it looked

Chidgey, A. P. & Boyd, R. L., 2008, In : Cell Stem Cell. 3, 4, p. 357 - 358 2 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Impact of the neuroendocrine system on thymus and bone marrow function

Barnard, A. L., Layton, D. S., Hince, M. N., Sakkal, S., Bernard, C. C. A., Chidgey, A. P. & Boyd, R. L., 2008, In : Neuroimmunomodulation. 15, 1, p. 7 - 18 12 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Strategies for reconstituting and boosting T cell-based immunity following haematopoietic stem cell transplantation: Pre-clinical and clinical approaches

Chidgey, A. P., Seach, N. L., Dudakov, J. A., Hammett, M. V. & Boyd, R. L., 2008, In : Seminars in Immunopathology. 30, 4, p. 457 - 477 21 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

The Lymphotoxin pathway regulates aire-independent expression of ectopic genes and chemokines in thymic stromal cells1

Seach, N. L., Ueno, T., Fletcher, A. L., Lowen, T. E., Mattesich, M., Engwerda, C. R., Scott, H. S., Ware, C. F., Chidgey, A. P., Gray, D. HD. & Boyd, R. L., 2008, In : Journal of Immunology. 180, 8, p. 5384 - 5392 9 p.

Research output: Contribution to journalArticleResearchpeer-review

80 Citations (Scopus)

The role of sex steroids and gonadectomy in the control of thymic involution

Hince, M. N., Sakkal, S., Vlahos, K., Dudakov, J. A., Boyd, R. L. & Chidgey, A. P., 2008, In : Cellular Immunology. 252, 1-2, p. 122 - 138 17 p.

Research output: Contribution to journalArticleResearchpeer-review

78 Citations (Scopus)

Tolerance strategies for stem-cell-based therapies

Chidgey, A. P., Layton, D. S., Trounson, A. O. & Boyd, R. L., 2008, In : Nature. 453, 7193, p. 330 - 337 8 p.

Research output: Contribution to journalArticleResearchpeer-review

83 Citations (Scopus)

Unbiased analysis, enrichment and purification of thymic stromal cells

Gray, D. H. D., Fletcher, A., Hammett, M., Seach, N. L., Ueno, T., Young, L. F., Barbuto, J., Boyd, R. L. & Chidgey, A. P., 2008, In : Journal of Immunological Methods. 329, p. 56 - 66 10 p.

Research output: Contribution to journalArticleResearchpeer-review

64 Citations (Scopus)
2007

A unique thymic fibroblast population revealed by the monoclonal antibody MTS-15

Gray, D. H. D., Tull, D., Ueno, T., Seach, N. L., Classon, B. J., Chidgey, A. P., McConville, M. J. & Boyd, R. L., 2007, In : Journal of Immunology. 178, 8, p. 4956 - 4965 10 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Enhanced immune reconstitution by sex steroid ablation following allogeneic hemopoietic stein cell transplantation

Goldberg, G. L., Alpdogan, Ö., Muriglan, S. J., Hammett, M. V., Milton, M. K., Eng, J. M., Hubbard, V. M., Kochman, A., Willis, L. M., Greenberg, A. S., Tjoe, K. H., Sutherland, J. S., Chidgey, A., Van Den Brink, M. R. M. & Boyd, R. L., 1 Jun 2007, In : Journal of Immunology. 178, 11, p. 7483-7484 2 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Enhanced immune reconstitution by sex steroid ablation following allogeneic hemopoietic stem cell transplantation.

Goldberg, G. L., Alpdogan, O., Muriglan, S. J., Hammett, M. V., Milton, M. K., Eng, J. M., Hubbard, V. M., Kochman, A. A., Willis, L. M., Greenberg, A. S., Tjoe, K. H., Sutherland, J. S., Chidgey, A. P., van den Brink, M. R. M. & Boyd, R. L., 2007, In : Journal of Immunology. 178, 11, p. 7473 - 7484 12 p.

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)

Impact of niche aging on thymic regeneration and immune reconstitution

Chidgey, A. P., Dudakov, J. A., Seach, N. L. & Boyd, R. L., 2007, In : Seminars in Immunology. 19, 5, p. 331 - 340 10 p.

Research output: Contribution to journalArticleResearchpeer-review

69 Citations (Scopus)

Redefining epithelial progenitor potential in the developing thymus

Rossi, S. W., Chidgey, A. P., Parnell, S. M., Jenkinson, W. E., Scott, H. S., Boyd, R. L., Jenkinson, E. J. & Anderson, G., 2007, In : European Journal of Immunology. 37, 9, p. 2411 - 2418 8 p.

Research output: Contribution to journalArticleResearchpeer-review

67 Citations (Scopus)

Thymic generation and regeneration: a new paradigm for establishing clinical tolerance of stem cell-based therapies

Seach, N. L., Layton, D. S., Lim, J. M. C., Chidgey, A. P. & Boyd, R. L., 2007, In : Current Opinion in Biotechnology. 18, 5, p. 441 - 447 7 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)
2006

Stemming the tide of thymic aging

Chidgey, A. P. & Boyd, R. L., 2006, In : Nature Immunology. 7, 10, p. 1013 - 1016 4 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)
2005

Activation of thymic regeneration in mice and humans following androgen blockade

Sutherland, J. S., Goldberg, G. L., Hammett, M. V., Uldrich, A. P., Berzins, S. P., Heng, T. S. P., Blazar, B. R., Millar, J. L., Malin, M., Chidgey, A. P. & Boyd, R. L., 2005, In : Journal of Immunology. 175, 4, p. 2741 - 2753 13 p.

Research output: Contribution to journalArticleResearchpeer-review

313 Citations (Scopus)

Controlling the thymic microenvironment

Gray, D. H. D., Ueno, T., Chidgey, A. P., Malin, M., Goldberg, G. L., Takahama, Y. & Boyd, R. L., 2005, In : Current Opinion in Immunology. 17, 2, p. 137 - 143 7 p.

Research output: Contribution to journalArticleResearchpeer-review

75 Citations (Scopus)