19972020

Research output per year

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Research Output

2020

Gelatin-based 3D microgels for in vitro T lineage cell generation

Suraiya, A. B., Hun, M., Truong, V. X., Forsythe, J. S. & Chidgey, A. P., 2 Mar 2020, (Accepted/In press) In : ACS Biomaterials Science and Engineering. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Gender Disparity Impacts on Thymus Aging and LHRH Receptor Antagonist-Induced Thymic Reconstitution Following Chemotherapeutic Damage

Hun, M. L., Wong, K., Gunawan, J. R., Alsharif, A. A. M., Quinn, K. & Chidgey, A. P., 3 Mar 2020, In : Frontiers in Immunology. 11, 20 p., 302.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids

Motazedian, A., Bruveris, F. F., Kumar, S. V., Schiesser, J. V., Chen, T., Ng, E. S., Chidgey, A. P., Wells, C. A., Elefanty, A. G. & Stanley, E. G., 6 Jan 2020, In : Nature Cell Biology. 22, 1, p. 60-73 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)
2019

Adding insult to injury: improving regenerative capacity of the aged thymus following clinically induced damage

Dudakov, J., Hun, M. L., Wong, K., Hollander, G. & Chidgey, A. P., 2 Apr 2019, Thymus Transcriptome and Cell Biology. Passos, G. (ed.). Switzerland: Springer, p. 273-294 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Decreased maternal serum acetate and impaired fetal thymic and regulatory T cell development in preeclampsia

Hu, M., Eviston, D., Hsu, P., Mariño, E., Chidgey, A., Santner-Nanan, B., Wong, K., Richards, J. L., Yap, Y. A., Collier, F., Quinton, A., Joung, S., Peek, M., Benzie, R., Macia, L., Wilson, D., Ponsonby, A. L., Tang, M. L. K., O’Hely, M., Daly, N. L. & 5 others, Mackay, C. R., Dahlstrom, J. E., The BIS Investigator Group, Vuillermin, P. & Nanan, R., 10 Jul 2019, In : Nature Communications. 10, 1, 13 p., 3031.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Interplay between Follistatin, Activin A, and BMP4 Signaling Regulates Postnatal Thymic Epithelial Progenitor Cell Differentiation during Aging

Lepletier, A., Hun, M. L., Hammett, M. V., Wong, K., Naeem, H., Hedger, M., Loveland, K. & Chidgey, A. P., 25 Jun 2019, In : Cell Reports. 27, 13, p. 3887–3901–e4 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)
2018

Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice

O'Sullivan, B. J., Yekollu, S., Ruscher, R., Mehdi, A., Maradana, M. R., Chidgey, A. P. & Thomas, R., 22 May 2018, In : Frontiers in Immunology. 9, MAY, 11 p., 1092.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2017

A novel Foxn1eGFP/+ mouse model identifies Bmp4-induced maintenance of Foxn1 expression and thymic epithelial progenitor populations

Barsanti, M., Lim, J. M. C., Hun, M. L., Lister, N., Wong, K., Hammett, M. V., Lepletier, A., Boyd, R. L., Giudice, A. & Chidgey, A. P., Feb 2017, In : European Journal of Immunology. 47, 2, p. 291-304 14 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Inflammation and Thymus Ageing

Lepletier, A., Alsharif, A. & Chidgey, A. P., 1 Jan 2017, Endocrine Immunology. Savino, W. & Guaraldi, F. (eds.). Karger, Vol. 48. p. 19-36 18 p. (Frontiers of Hormone Research).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

1 Citation (Scopus)

Native thymic extracellular matrix improves in vivo thymic organoid T cell output, and drives in vitro thymic epithelial cell differentiation

Hun, M., Barsanti, M., Wong, K., Ramshaw, J., Werkmeister, J. & Chidgey, A. P., Feb 2017, In : Biomaterials. 118, p. 1-15 15 p., 145253.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)
2016

In situ -forming click-crosslinked gelatin based hydrogels for 3D culture of thymic epithelial cells

Truong, V. X., Hun, M. L., Li, F., Chidgey, A. P. & Forsythe, J. S., 1 Jul 2016, In : Biomaterials Science. 4, 7, p. 1123-1131 9 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Strategies for thymic regeneration: Recent advances towards clinical therapy

Barsanti, M., Hun, M., Boyd, R. & Chidgey, A., 1 Jan 2016, Synthetic Immunology. Watanabe, T. & Takahama, Y. (eds.). Japan: Springer, p. 57-94 38 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

1 Citation (Scopus)
2015

Enhanced hematopoietic stem cell function mediates immune regeneration following sex steroid blockade

Khong, D. M., Dudakov, J. A., Hammett, M. V., Jurblum, M. I., Khong, S. M. L., Goldberg, G. L., Ueno, T., Spyroglou, L. G., Young, L. F., van den Brink, M. R. M., Boyd, R. L. & Chidgey, A. P., 2015, In : Stem Cell Reports. 4, 3, p. 445 - 458 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
13 Citations (Scopus)

New role for the (pro)renin receptor in T-cell development

Geisberger, S., Maschke, U., Gebhardt, M., Kleinewietfeld, M., Manzel, A., Linker, R. A., Chidgey, A. P., Dechend, R., Nguyen, G., Daumke, O., Muller, D. N., Wright, M. D. & Binger, K. J., 2015, In : Blood. 126, 4, p. 504 - 507 4 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Perspectives for improvement of the thymic microenvironment through manipulation of thymic epithelial cells: a mini-review

Lepletier, A., Chidgey, A. P. & Savino, W., 2015, In : Gerontology. 61, 6, p. 504-514 11 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)
2014

Establishment of transplantation tolerance via minimal conditioning in aged recipients

Morison, J. K., Homann, J., Hammett, M. V., Seach, N. L., Layton, D. S., Malin, M. A., Thorburn, A. N., Chidgey, A. P., Boyd, R. L. & Heng, T. S. P., 2014, In : American Journal of Transplantation. 14, 11, p. 2478 - 2490 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

FOXN1GFP/w reporter hESCs enable identification of integrin-a4, HLA-DR, and EpCAM as markers of human PSC-derived FOXN1 + thymic epithelial progenitors

Soh, C-L., Giudice, A., Jenny, R. A., Elliott, D. A., Hatzistavrou, T., Micallef, S. J., Kianizad, K., Seach, N. L., Zuniga-Pflucker, J. C., Chidgey, A. P., Trounson, A. O., Nilsson, S. S. K., Haylock, D. N., Boyd, R. L., Elefanty, A. G. & Stanley, E. G., 2014, In : Stem Cell Reports. 2, 6, p. 925 - 937 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
16 Citations (Scopus)

Multilineage potential and self-renewal define an epithelial progenitor cell population in the adult thymus

Wong, K. Y. P., Seach, N. L., Barsanti, M., Lim, J. M. C., Hammett, M. V., Khong, D. M., Siatskas, C., Gray, D. H. D., Boyd, R. L. & Chidgey, A. P., 2014, In : Cell Reports. 8, 4, p. 1198 - 1209 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
74 Citations (Scopus)
2013

Isolation, characterization, and reaggregate culture of thymic epithelial cells

Seach, N. L., Hammett, M. V. & Chidgey, A. P., 2013, In : Methods in Molecular Biology. 945, p. 251 - 272 22 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Newborn stem cells: identity, function, and clinical potential

Park, A., Chidgey, A. P., Boyd, R. L., Chan, L., Gohel, M. D. I., Murphy, S. & Manuelpillai, U. C., 2013, Perinatal Stem Cells. Cetrulo, K. J., Cetrulo Jr, C. L. & Taghizadeh, R. R. (eds.). 2nd ed. USA: John Wiley & Sons, p. 119 - 137 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

3 Citations (Scopus)

Rewiring immunity: Generating a functional thymus from hESCs... are we there yet?

Boyd, R. L., Soh, C-L., Boyd, N. R., Stanley, E. G. & Chidgey, A. P., 1 Aug 2013, In : Cell Stem Cell. 13, 2, p. 135-136 2 p.

Research output: Contribution to journalLetterOther

Open Access
File
3 Citations (Scopus)

The immunogenicity of stem cells and thymus-based strategies to minimise immune rejection

Morison, J., Heng, T. S. P., Chidgey, A. P. & Boyd, R. L., 1 Jan 2013, The Immunological Barriers to Regenerative Medicine. Fairchild, P. J. (ed.). 1st ed. USA: Humana Press, p. 201-223 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

The role of Tenascin C in the lymphoid progenitor cell niche

Ellis, S. L., Heazlewood, S. Y., Williams, B., Reitsma, A. J., Grassinger, J., Borg, J., Heazlewood, C. K., Chidgey, A. P. & Nilsson, S. K., 2013, In : Experimental Hematology. 41, 12, p. 1050 - 1061 12 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Thymic deletion and regulatory T cells prevent antimyeloperoxidase GN

Tan, D. S. Y., Gan, P. Y., O'Sullivan, K., Hammett, M. V., Summers, S. A., Ooi, J., Lundgren, B. A., Boyd, R. L., Scott, H. S., Kitching, A. R., Chidgey, A. P. & Holdsworth, S. R., 2013, In : Journal of the American Society of Nephrology. 24, 4, p. 573 - 585 13 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)
2012

Purified enzymes improve isolation and characterization of the adult thymic epithelium

Seach, N. L., Wong, K., Hammett, M. V., Boyd, R. L. & Chidgey, A. P., 2012, In : Journal of Immunological Methods. 385, 1-2, p. 23 - 34 12 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)
2011

Androgen reduction and mesenchymal stem cell therapies improve kinetics of thymic epithelial cell recovery following chemotherapy

Calder, A., Parolini, O. (ed.), Lister, N. L., Manuelpillai, U. (ed.), Fletcher, A. L., Redl, H. (ed.), Hammett, M. V., Zeisberger, S. (ed.), Boyd, R. L. & Chidgey, A. P., 2011, p. 322 - 333. 12 p.

Research output: Contribution to conferenceAbstract

14 Citations (Scopus)

The contribution of thymic stromal abnormalities to autoimmune disease

Fletcher, A., Calder, A., Hince, M., Boyd, R. & Chidgey, A., 2011, In : Critical Reviews in Immunology. 31, 3, p. 171 - 187 17 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Thymic involution: Where endocrinology meets immunology

Calder, A., Hince, M., Dudakov, J., Chidgey, A. & Boyd, R., 2011, In : Neuroimmunomodulation. 18, 5, p. 281 - 289 9 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)
2010

Feeding the fire: the role of defective bone marrow function in exacerbating thymic involution

Dudakov, J. A., Khong, D. M. P., Boyd, R. L. & Chidgey, A. P., 2010, In : Trends in Immunology. 31, 5, p. 191 - 198 8 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Getting back at nature: Understanding thymic development and overcoming its atrophy

Heng, T. S. P., Chidgey, A. P. & Boyd, R. L., 2010, In : Current Opinion in Pharmacology. 10, 4, p. 425 - 433 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

29 Citations (Scopus)

Regeneration of dendritic cells in aged mice

van Dommelen, S. LH., Rizzitelli, A., Chidgey, A. P., Boyd, R. L., Shortman, K. & Wu, L., 2010, In : Cellular & Molecular Immunology. 7, 2, p. 108 - 115 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Sex steroid ablation enhances immune reconstitution following cytotoxic antineoplastic therapy in young mice

Goldberg, G. L., Dudakov, J. A., Reiseger, J. J., Seach, N. L., Ueno, T., Vlahos, K., Hammett, M. V., Young, L. F., Heng, T. S. P., Boyd, R. L. & Chidgey, A. P., 2010, In : Journal of Immunology. 184, 11, p. 6014 - 6024 11 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Stem Cells and Regenerative Medicine - The Evolving Story

Chidgey, A., Seach, N., Lim, R. & Boyd, R., 2010, Stem Cell Technologies - Basics and Applications. Totey, S. & Deb, K. (eds.). 1st ed. USA: McGraw-Hill Education, p. 1 - 18 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2009

Ablation and regeneration of tolerance-inducing medullary thymic epithelial cells after cyclosporine, cyclophosphamide, and dexamethasone treatment

Fletcher, A. L., Lowen, T. E., Sakkal, S., Reiseger, J. J., Hammett, M. V., Seach, N. L., Scott, H. S., Boyd, R. L. & Chidgey, A. P., 2009, In : Journal of Immunology. 183, 2, p. 823 - 831 9 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)

Androgen depletion increases the efficacy of bone marrow transplantation in ameliorating experimental autoimmune encephalomyelitis

Barnard, A. L., Chidgey, A. P., Bernard, C. C. A. & Boyd, R. L., 2009, In : Blood. 113, p. 204 - 213 9 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Characterization of the thymic IL-7 niche in vivo

Alves, N. L., Richard-Le Goff, O., Huntington, N. D., Sousa, A. P., Ribeiro, V. S. G., Bordack, A., Vives, F. L., Peduto, L., Chidgey, A. P., Cumano, A., Boyd, R. L., Eberl, G. & Di Santo, J. P., 2009, In : Proceedings of the National Academy of Sciences. 106, 5, p. 1512 - 1517 6 p.

Research output: Contribution to journalArticleResearchpeer-review

89 Citations (Scopus)

Epithelial stem cells and the development of the thymus, parathyroid, and skin

Soh, C-L., Lim, J. M. C., Boyd, R. L. & Chidgey, A. P., 2009, Regulatory Networks in Stem Cells. Rajasekhar, V. K. & Vemuri, M. C. (eds.). 1st ed. Germany: Humana Press, p. 405 - 437 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Luteinizing hormone-releasing hormone enhances T cell recovery following allogeneic bone marrow transplantation

Goldberg, G. L., King, C. G., Nejat, R. A., Suh, D. Y., Smith, O. M., Bretz, J. C., Samstein, R. M., Dudakov, J. A., Chidgey, A. P., Chen-Kiang, S., Boyd, R. L. & van den Brink, M. R. M., 2009, In : Journal of Immunology. 182, 9, p. 5846 - 5854 9 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Sex steroid ablation enhances hematopoietic recovery following cytotoxic antineoplastic therapy in aged mice

Dudakov, J. A., Goldberg, G. L., Reiseger, J. J., Vlahos, K., Chidgey, A. P. & Boyd, R. L., 2009, In : Journal of Immunology. 183, 11, p. 7084 - 7094 11 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Stem cells-meet immunity

Heng, T. S. P., Dudakov, J. A., Khong, D. M. P., Chidgey, A. P. & Boyd, R. L., 2009, In : Journal of Molecular Medicine. 87, 11, p. 1061 - 1069 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

10 Citations (Scopus)

The global thymus network: Past, present and future

Takahama, Y., Saito, T., Kawamoto, H., Itoi, M., Boyd, R. L., Chidgey, A., Zamoyska, R., Hollander, G. A., Anderson, G., Taylor, N., Petrie, H. T. & Nikolich-Zugich, J., May 2009, In : Trends in Immunology. 30, 5, p. 191-192 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

1 Citation (Scopus)

Thymic involution and immune reconstitution

Lynch, H. E., Goldberg, G. L., Chidgey, A. P., van den Brink, M. R. M., Boyd, R. L. & Sempowski, G. D., 2009, In : Trends in Immunology. 30, 7, p. 366 - 373 8 p.

Research output: Contribution to journalArticleResearchpeer-review

257 Citations (Scopus)

Thymic regeneration in mice and humans following sex steroid ablation

Fletcher, A. L., Reiseger, J. J., Vlahos, K., Seach, N. L., Dudakov, J. A., Chidgey, A. P. & Boyd, R. L., 2009, Handbook on Immunosensecence: Basic understanding and clinical applications. Fulop, T., Franceschi, C., Hirokawa, K. & Pawelec, G. (eds.). 1st ed. Germany: Springer, p. 1571 - 1609 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

1 Citation (Scopus)

VEGF-mediated cross-talk within the neonatal murine thymus

Cuddihy, A. R., Ge, S., Zhu, J., Jang, J., Chidgey, A. P., Thurston, G., Boyd, R. L. & Crooks, G. M., 2009, In : Blood. 113, p. 2723 - 2731 8 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Withdrawal of sex steroids reverses age- and chemotherapy-related defects in bone marrow lymphopoiesis

Dudakov, J. A., Goldberg, G. L., Reiseger, J. J., Chidgey, A. P. & Boyd, R. L., 2009, In : Journal of Immunology. 182, 10, p. 6247 - 6260 14 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Effects of growth hormone in enhancing thymic regrowth and T-cell reconstitution

Chidgey, A. P., 2008, In : Expert Review of Clinical Immunology. 4, 4, p. 433 - 439 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Enhanced immune system regeneration in humans following allogeneic or autologous hemopoietic stem cell transplantation by temporary sex steroid blockade

Sutherland, J. S., Spyroglou, L. G., Muirhead, J. L., Heng, T. S. P., Prieto-Hinojosa, A., Prince, H. M., Chidgey, A. P., Schwarer, A. P. & Boyd, R. L., 2008, In : Clinical Cancer Research. 14, 4, p. 1138 - 1149 12 p.

Research output: Contribution to journalArticleResearchpeer-review

77 Citations (Scopus)

Immune privilege for stem cells: Not as simple as it looked

Chidgey, A. P. & Boyd, R. L., 2008, In : Cell Stem Cell. 3, 4, p. 357 - 358 2 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Impact of the neuroendocrine system on thymus and bone marrow function

Barnard, A. L., Layton, D. S., Hince, M. N., Sakkal, S., Bernard, C. C. A., Chidgey, A. P. & Boyd, R. L., 2008, In : Neuroimmunomodulation. 15, 1, p. 7 - 18 12 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)