20052018
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Research Output 2005 2018

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2018
3 Citations (Scopus)

Fine Tuning of Canonical Wnt Stimulation Enhances Differentiation of Pluripotent Stem Cells Independent of β-Catenin-Mediated T-Cell Factor Signaling

Chen, J., Nefzger, C. M., Rossello, F., Sun, Y. B. Y., Lim, S. M., Liu, X., De Boer, S., Knaupp, A. S., Li, J., Davidson, K. C., Polo, J. M. & Barberi, T., 1 Jun 2018, In : Stem Cells. 36, 6, p. 822-833 12 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

SRSF3 promotes pluripotency through nanog mRNA export and coordination of the pluripotency gene expression program

Ratnadiwakara, M., Archer, S. K., Dent, C. I., Ruiz De Los Mozos, I., Beilharz, T. H., Knaupp, A. S., Nefzger, C. M., Polo, J. M. & Anko, M-L., 9 May 2018, In : eLife. 7, 28 p., e37419.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2017
14 Citations (Scopus)

Cell Type of Origin Dictates the Route to Pluripotency

Nefzger, C. M., Rossello, F. J., Chen, J., Liu, X., Knaupp, A. S., Firas, J., Paynter, J. M., Pflueger, J., Buckberry, S., Lim, S. M., Williams, B., Alaei, S., Faye-Chauhan, K., Petretto, E., Nilsson, S. K., Lister, R., Ramialison, M., Powell, D. R., Rackham, O. J. L. & Polo, J. M., 5 Dec 2017, In : Cell Reports. 21, 10, p. 2649-2660 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
22 Citations (Scopus)

Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming

Liu, X., Nefzger, C. M., Rossello, F. J., Chen, J., Knaupp, A. S., Firas, J., Ford, E., Pflueger, J., Paynter, J. M., Chy, H. S., O'Brien, C. M., Huang, C., Mishra, K., Hodgson-Garms, M., Jansz, N., Williams, S. M., Blewitt, M. E., Nilsson, S. K., Schittenhelm, R. B., Laslett, A. L. & 2 others, Lister, R. & Polo, J. M., 31 Oct 2017, In : Nature Methods. 14, 11, p. 1055-1062 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
24 Citations (Scopus)

Transient and Permanent Reconfiguration of Chromatin and Transcription Factor Occupancy Drive Reprogramming

Knaupp, A. S., Buckberry, S., Pflueger, J., Lim, S. M., Ford, E., Larcombe, M. R., Rossello, F. J., de Mendoza, A., Alaei, S., Firas, J., Holmes, M. L., Nair, S. S., Clark, S. J., Nefzger, C. M., Lister, R. & Polo, J. M., 7 Dec 2017, In : Cell Stem Cell. 21, 6, p. 834-845.e6 18 p.

Research output: Contribution to journalArticleResearchpeer-review

2016
4 Citations (Scopus)

An improved reprogrammable mouse model harbouring the reverse tetracycline-controlled transcriptional transactivator 3

Alaei, S., Knaupp, A. S., Lim, S. M., Chen, J., Holmes, M. L., Ankö, M-L., Nefzger, C. M. & Polo, J. M., 1 Jul 2016, In : Stem Cell Research. 17, 1, p. 49-53 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

A Versatile Strategy for Isolating a Highly Enriched Population of Intestinal Stem Cells

Nefzger, C. M., Jarde, T., Rossello, F. J., Horvay, K., Knaupp, A. S., Powell, D. R., Chen, J. Y., Abud, H. E. & Polo, J. M., 2016, In : Stem Cell Reports. 6, 3, p. 321 - 329 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2014
10 Citations (Scopus)

Cell surface marker mediated purification of iPS cell intermediates from a reprogrammable mouse model

Nefzger, C. M., Alaei Shehni, S., Knaupp, A. S., Holmes, M. L. & Polo, J. M., 2014, In : Journal of Visualized Experiments. 91, (Art. No.: e51728), p. 1 - 8 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Epigenetic Changes During Reprogramming

Alaei Shehni, S., Knaupp, A. S. & Polo, J. M., 2014, In : Australian Biochemist. 45, 1, p. 17 - 20 4 p.

Research output: Contribution to journalArticleOther

18 Citations (Scopus)

Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase

Samson, A. L., Knaupp, A. S., Kass, I., Kleifeld, O., Marijanovic, E. M., Hughes, V. A., Lupton, C. J., Buckle, A. M., Bottomley, S. P. & Medcalf, R. L., 2014, In : Journal of Biological Chemistry. 289, 39, p. 26922 - 26936 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
12 Citations (Scopus)

The roles of helix I and strand 5A in the folding, function and misfolding of alpha1-antitrypsin

Knaupp, A. S., Keleher, S. B., Yang, L. L., Dai, W., Bottomley, S. P. & Pearce, M. C., 2013, In : PLoS ONE. 8, 1, 8 p., e54766.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2012
17 Citations (Scopus)

Conformational properties of the disease-causing Z variant of a1-antitrypsin revealed by theory and experiment

Kass, I., Knaupp, A., Bottomley, S. P. & Buckle, A. M., 2012, In : Biophysical Journal. 102, 12, p. 2856 - 2865 10 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin

Samson, A. L., Knaupp, A. S., Sashindranath, M., Borg, R. J., Au, A. E-L., Cops, E. J., Saunders, H. M., Cody, S. H., McLean, C. A., Nowell, C., Hughes, V. A., Bottomley, S. P. & Medcalf, R. L., 2012, In : Cell Reports. 2, 4, p. 889 - 901 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2011
14 Citations (Scopus)

Structural change in beta-sheet A of Z alpha{1}-antitrypsin is responsible for accelerated polymerization and disease

Knaupp, A. S. & Bottomley, S. P., 2011, In : Journal of Molecular Biology. 413, 4, p. 888 - 898 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
35 Citations (Scopus)

Kinetic instability of the serpin Z alpha1-antitrypsin promotes aggregation

Knaupp, A. S., Levina, V., Robertson, A. L., Pearce, M. C. & Bottomley, S. P., 2010, In : Journal of Molecular Biology. 396, 2, p. 375 - 383 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
19 Citations (Scopus)

Expression, purification and characterization of recombinant Z alpha1-Antitrypsin-The most common cause of alpha1-Antitrypsin deficiency

Levina, V., Dai, W., Knaupp, A. S., Kaiserman, D., Pearce, M. C., Cabrita, L. D., Bird, P. I. & Bottomley, S. P., 2009, In : Protein Expression and Purification. 68, 2, p. 226 - 232 7 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Serpin polymerization and its role in disease - The molecular basis of alpha1-antitrypsin deficiency

Knaupp, A. S. & Bottomley, S. P., 2009, In : IUBMB Life. 61, 1, p. 1 - 5 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
5 Citations (Scopus)

A 191-kb genomic fragment containing the human α-globin locus can rescue α-thalassemic mice

Al-Hasani, K., Vadolas, J., Knaupp, A. S., Wardan, H., Voullaire, L., Williamson, R. & Ioannou, P. A., 1 Nov 2005, In : Mammalian Genome. 16, 11, p. 847-853 7 p.

Research output: Contribution to journalArticleResearchpeer-review