20132019
If you made any changes in Pure these will be visible here soon.

Research Output 2013 2019

  • 8 Article
  • 1 Chapter (Book)
  • 1 Comment / Debate
  • 1 Review Article
2019

Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics

Greule, A., Izoré, T., Iftime, D., Tailhades, J., Schoppet, M., Zhao, Y., Peschke, M., Ahmed, I., Kulik, A., Adamek, M., Goode, R. J. A., Schittenhelm, R. B., Kaczmarski, J. A., Jackson, C. J., Ziemert, N., Krenske, E. H., De Voss, J. J., Stegmann, E. & Cryle, M. J., 13 Jun 2019, In : Nature Communications. 10, 1, 15 p., 2613.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Studying trans-acting enzymes that target carrier protein-bound amino acids during nonribosomal peptide synthesis

Greule, A., Charkoudian, L. K. & Cryle, M. J., 1 Jan 2019, Metabolons and Supramolecular Enzyme Assemblies. Schmidt-Dannert, C. & Quin, M. B. (eds.). Academic Press, p. 113-154 42 p. (Methods in Enzymology; vol. 617).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2018

A route to diastereomerically pure phenylglycine thioester peptides: Crucial intermediates for investigating glycopeptide antibiotic biosynthesis

Tailhades, J., Schoppet, M., Greule, A., Peschke, M., Brieke, C. & Cryle, M. J., 9 Feb 2018, In : Chemical Communications. 54, 17, p. 2146-2149 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach

Brieke, C., Tarnawski, M., Greule, A. & Cryle, M. J., 1 Aug 2018, In : Journal of Inorganic Biochemistry. 185, p. 43-51 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Unrivalled diversity: the many roles and reactions of bacterial cytochromes P450 in secondary metabolism

Greule, A., Stok, J. E., De Voss, J. J. & Cryle, M., 1 Aug 2018, In : Natural Product Reports. 35, 8, p. 757-791 35 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
2017

From a natural product to its biosynthetic gene cluster: A demonstration using polyketomycin from Streptomyces diastatochromogenes tü6028

Greule, A., Zhang, S., Paululat, T. & Bechthold, A., 13 Jan 2017, In : Journal of Visualized Experiments. 2017, 119, e54952.

Research output: Contribution to journalArticleResearchpeer-review

Wide distribution of foxicin biosynthetic gene clusters in Streptomyces strains - An unusual secondary metabolite with various properties

Greule, A., Marolt, M., Deubel, D., Peintner, I., Zhang, S., Jessen-Trefzer, C., De Ford, C., Burschel, S., Li, S. M., Friedrich, T., Merfort, I., Lüdeke, S., Bisel, P., Müller, M., Paululat, T. & Bechthold, A., 21 Feb 2017, In : Frontiers in Microbiology. 8, FEB, 221.

Research output: Contribution to journalArticleResearchpeer-review

2016

Thailandins A and B, New Polyene Macrolactone Compounds Isolated from Actinokineospora bangkokensis Strain 44EHWT, Possessing Antifungal Activity against Anthracnose Fungi and Pathogenic Yeasts

Intra, B., Greule, A., Bechthold, A., Euanorasetr, J., Paululat, T. & Panbangred, W., 29 Jun 2016, In : Journal of Agricultural and Food Chemistry. 64, 25, p. 5171-5179 9 p.

Research output: Contribution to journalArticleResearchpeer-review

The draft genome sequence of Actinokineospora bangkokensis 44EHWT reveals the biosynthetic pathway of the antifungal thailandin compounds with unusual butylmalonyl-CoA extender units

Greule, A., Intra, B., Flemming, S., Rommel, M. G. E., Panbangred, W. & Bechthold, A., 1 Nov 2016, In : Molecules. 21, 11, 1607.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2015

Minimum Information about a Biosynthetic Gene cluster

Medema, M. H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J. B., Blin, K., De Bruijn, I., Chooi, Y. H., Claesen, J., Coates, R. C., Cruz-Morales, P., Duddela, S., Düsterhus, S., Edwards, D. J., Fewer, D. P., Garg, N., Geiger, C., Gomez-Escribano, J. P., Greule, A., Hadjithomas, M. & 134 othersHaines, A. S., Helfrich, E. J. N., Hillwig, M. L., Ishida, K., Jones, A. C., Jones, C. S., Jungmann, K., Kegler, C., Kim, H. U., Kötter, P., Krug, D., Masschelein, J., Melnik, A. V., Mantovani, S. M., Monroe, E. A., Moore, M., Moss, N., Nützmann, H. W., Pan, G., Pati, A., Petras, D., Reen, F. J., Rosconi, F., Rui, Z., Tian, Z., Tobias, N. J., Tsunematsu, Y., Wiemann, P., Wyckoff, E., Yan, X., Yim, G., Yu, F., Xie, Y., Aigle, B., Apel, A. K., Balibar, C. J., Balskus, E. P., Barona-Gómez, F., Bechthold, A., Bode, H. B., Borriss, R., Brady, S. F., Brakhage, A. A., Caffrey, P., Cheng, Y. Q., Clardy, J., Cox, R. J., De Mot, R., Donadio, S., Donia, M. S., Van Der Donk, W. A., Dorrestein, P. C., Doyle, S., Driessen, A. J. M., Ehling-Schulz, M., Entian, K. D., Fischbach, M. A., Gerwick, L., Gerwick, W. H., Gross, H., Gust, B., Hertweck, C., Höfte, M., Jensen, S. E., Ju, J., Katz, L., Kaysser, L., Klassen, J. L., Keller, N. P., Kormanec, J., Kuipers, O. P., Kuzuyama, T., Kyrpides, N. C., Kwon, H. J., Lautru, S., Lavigne, R., Lee, C. Y., Linquan, B., Liu, X., Liu, W., Luzhetskyy, A., Mahmud, T., Mast, Y., Méndez, C., Metsä-Ketelä, M., Micklefield, J., Mitchell, D. A., Moore, B. S., Moreira, L. M., Müller, R., Neilan, B. A., Nett, M., Nielsen, J., O'Gara, F., Oikawa, H., Osbourn, A., Osburne, M. S., Ostash, B., Payne, S. M., Pernodet, J. L., Petricek, M., Piel, J., Ploux, O., Raaijmakers, J. M., Salas, J. A., Schmitt, E. K., Scott, B., Seipke, R. F., Shen, B., Sherman, D. H., Sivonen, K., Smanski, M. J., Sosio, M., Stegmann, E., Süssmuth, R. D., Tahlan, K., Thomas, C. M., Tang, Y., Truman, A. W., Viaud, M., Walton, J. D., Walsh, C. T., Weber, T., Van Wezel, G. P., Wilkinson, B., Willey, J. M., Wohlleben, W., Wright, G. D., Ziemert, N., Zhang, C., Zotchev, S. B., Breitling, R., Takano, E. & Glöckner, F. O., 18 Aug 2015, In : Nature Chemical Biology. 11, 9, p. 625-631 7 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
File
2013

The AT2 domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS

Musiol, E. M., Greule, A., Härtner, T., Kulik, A., Wohlleben, W. & Weber, T., Jul 2013, In : ChemBioChem. 14, 11, p. 1343-1352 10 p.

Research output: Contribution to journalArticleResearchpeer-review