20132020

Research output per year

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Research Output

  • 8 Article
  • 2 Review Article
  • 1 Chapter (Book)
2020

Assays for Measuring the Role of MIF in NLRP3 Inflammasome Activation

Pinar, A. A. & Harris, J., 2020, Macrophage Migration Inhibitory Factor: Methods and Protocols. Harris, J. & Morand, E. F. (eds.). New York, NY: Humana Press, Vol. 2080. p. 159-172 14 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Open Access
File

Targeting the NLRP3 inflammasome to treat cardiovascular fibrosis

Pinar, A. A., Scott, T. E., Huuskes, B. M., Tapia Cáceres, F. E., Kemp-Harper, B. K. & Samuel, C. S., May 2020, In : Pharmacology and Therapeutics. 209, 22 p., 107511.

Research output: Contribution to journalReview ArticleResearchpeer-review

The anti-fibrotic actions of relaxin are mediated through AT2R-associated protein phosphatases via RXFP1-AT2R functional crosstalk in human cardiac myofibroblasts

Wang, C., Pinar, A. A., Widdop, R. E., Hossain, M. A., Bathgate, R. A. D., Denton, K. M., Kemp-Harper, B. K. & Samuel, C. S., 16 Apr 2020, (Accepted/In press) In : The FASEB Journal. 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2019

Serelaxin inhibits the profibrotic TGF-β1/IL-1β axis by targeting TLR-4 and the NLRP3 inflammasome in cardiac myofibroblasts

Tapia Caceres, F., Gaspari, T. A., Samuel, C. S. & Pinar, A. A., 1 Dec 2019, In : The FASEB Journal. 33, 12, p. 14717-14733 17 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

Lang, T., Lee, J. P. W., Elgass, K., Pinar, A. A., Tate, M. D., Aitken, E. H., Fan, H., Creed, S. J., Deen, N. S., Traore, D. A. K., Mueller, I., Stanisic, D., Baiwog, F. S., Skene, C., Wilce, M. C. J., Mansell, A., Morand, E. F. & Harris, J., 1 Dec 2018, In : Nature Communications. 9, 1, 15 p., 2223.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
29 Citations (Scopus)
2017

PB1-F2 peptide derived from avian influenza A virus H7N9 induces inflammation via activation of the NLRP3 inflammasome

Pinar, A., Dowling, J. K., Bitto, N. J., Robertson, A. A. B., Latz, E., Stewart, C. R., Drummond, G. R., Cooper, M. A., McAuley, J. L., Tate, M. D. & Mansell, A., 20 Jan 2017, In : Journal of Biological Chemistry. 292, 3, p. 826-836 11 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages

Alvarado, R., To, J., Lund, M. E., Pinar, A., Mansell, A., Robinson, M. W., O'Brien, B. A., Dalton, J. P. & Donnelly, S. M., 1 Jan 2017, In : The FASEB Journal. 31, 1, p. 85-95 11 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)
2016

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice

Krishnan, S. M., Dowling, J. K., Ling, Y. H., Diep, H., Chan, C. T., Ferens, D., Kett, M. M., Pinar, A., Samuel, C. S., Vinh, A., Arumugam, T. V., Hewitson, T. D., Kemp-Harper, B. K., Robertson, A. A. B., Cooper, M. A., Latz, E., Mansell, A., Sobey, C. G. & Drummond, G. R., 1 Feb 2016, In : British Journal of Pharmacology. 173, 4, p. 752-765 14 p.

Research output: Contribution to journalArticleResearchpeer-review

65 Citations (Scopus)
2013

Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease

McAuley, J., Tate, M., Mackenzie-kludas, C., Pinar, A., Zeng, W., Stutz, A., Latz, E., Brown, L. E. & Mansell, A. S., 2013, In : PLoS Pathogens. 9, 5 (art. no. e1003392 ), p. 1 - 14 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
107 Citations (Scopus)

Characterization of forebrain neurons derived from late-onset Huntington's disease human embryonic stem cell lines

Niclis, J. C., Pinar, A., Haynes, J. M., Alsanie, W. F., Jenny, R. A., Dottori, M. & Cram, D. S., 2013, In : Frontiers in Cellular Neuroscience. 7, 37, p. 1 - 13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
25 Citations (Scopus)