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Research Output 2002 2018

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Article
2018
38 Citations (Scopus)

Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1

Teh, T. C., Nguyen, N. Y., Moujalled, D. M., Segal, D., Pomilio, G., Rijal, S., Jabbour, A., Cummins, K., Lackovic, K., Blombery, P., Thompson, E., Ekert, P. G., Lessene, G., Glaser, S. P., Huang, D. C. S., Roberts, A. W., Guthridge, M. A. & Wei, A. H., 1 Feb 2018, In : Leukemia. 32, 2, p. 303-312 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
22 Citations (Scopus)

Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations

Green, B. D., Jabbour, A. M., Sandow, J. J., Riffkin, C. D., Masouras, D., Daunt, C. P., Salmanidis, M., Brumatti, G., Hemmings, B., Guthridge, M. A., Pearson, R. B. & Ekert, P. G., 2013, In : Cell Death and Differentiation. 20, 10, p. 1341 - 1349 9 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia

Brumatti, G., Salmanidis, M., Kok, C. H., Bilardi, R. A., Sandow, J. J., Silke, N., Mason, K. D., Visser, J. A. L., Jabbour, A., Glaser, S. P., Okamoto, T., Bouillet, P., D'Andrea, R. J. & Ekert, P. G., 2013, In : Oncotarget. 4, 11, p. 1933 - 1947 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
19 Citations (Scopus)

Hoxb8 regulates expression of microRNAs to control cell death and differentiation

Salmanidis, M., Brumatti, G., Narayan, N., Green, B. D., van den Bergen, J. A., Sandow, J. J., Bert, A. G., Silke, N., Sladic, R., Puthalakath, H., Rohrbeck, L., Okamoto, T., Bouillet, P., Herold, M. J., Goodall, G. J., Jabbour, A. & Ekert, P. G., 2013, In : Cell Death and Differentiation. 20, 10, p. 1370 - 1380 11 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription

Thomas, D., Powell, J. A., Vergez, F., Segal, D., Nguyen, N-Y. N., Baker, A., Teh, T-C., Barry, E. F., Sarry, J-E., Lee, E. M., Nero, T. L., Jabbour, A. M., Pomilio, G., Green, B. D., Manenti, S., Glaser, S. P., Parker, M. W., Lopez, A. F., Ekert, P. G., Lock, R. B. & 5 others, Huang, D. CS., Nilsson, S. K., Recher, C., Wei, A. & Guthridge, M. A., 2013, In : Blood. 122, 5, p. 738 - 748 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts

Bandopadhayay, P., Jabbour, A. M., Riffkin, C. D., Salmanidis, M., Gordon, L., Popovski, D., Rigby, L., Ashely, D. M., Watkins, D. N., Thomas, D. M., Algar, E. M. & Ekert, P. G., 2013, In : BMC Cancer. 13, Art # 585, p. 1 - 14 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2012
22 Citations (Scopus)

Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death

Sandow, J. J., Jabbour, A., Condina, M. R., Daunt, C., Stomski, F., Green, B., Riffkin, C., Hoffmann, P., Guthridge, M., Silke, J., Lopez, A. F. & Ekert, P., 2012, In : Cell Death and Differentiation. 19, 4, p. 633 - 641 9 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

p53-dependent transcriptional responses to interleukin-3 signaling

Jabbour, A., Gordon, L., Daunt, C. P., Green, B. D., Kok, C. H., D'Andrea, R. J. & Ekert, P. G., 2012, In : PLoS ONE. 7, 2, 11 p., e31428.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2010
25 Citations (Scopus)

Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation

Jabbour, A., Daunt, C. P., Green, B. D., Vogel, S., Gordon, L., Lee, R. S-H., Silke, N., Pearson, R. B., Vandenberg, C. J., Kelly, P., Nutt, S. L., Strasser, A., Borner, C. & Ekert, P. G., 2010, In : Blood. 115, 2, p. 344 - 352 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2009
59 Citations (Scopus)

Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim

Jabbour, A., Heraud, J. E., Daunt, C. P., Kaufmann, T., Sandow, J. J., O'Reilly, L. A., Callus, B. A., Lopez, A. F., Strasser, A., Vaux, D. L. & Ekert, P. G., 2009, In : Cell Death and Differentiation. 16, 4, p. 555 - 563 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2008
58 Citations (Scopus)

Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma

Ekert, P. G., Jabbour, A., Manoharan, A., Heraud, J. E., Yu, J. Y., Pakusch, M., Michalak, E. M., Kelly, P., Callus, B. A., Kiefer, T., Verhagen, A. M., Silke, J., Strasser, A., Borner, C. & Vaux, D. L., 2008, In : Blood. 108, 5, p. 1461 - 1468 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Triggering of Apoptosis by Puma Is Determined by the Threshold Set by Prosurvival Bcl-2 Family Proteins

Callus, B. A., Moujallad, D. M., Silke, J., Gerl, R., Jabbour, A., Ekert, P. G. & Faux, D. L., 2008, In : Journal of Molecular Biology. 384, p. 313 - 323 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2006
20 Citations (Scopus)

Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1

Jabbour, A. M., Puryer, M. A., Yu, J. Y., Lithgow, T. J., Riffkin, C. D., Ashley, D. M., Vaux, D. L., Ekert, P. G. & Hawkins, C. J., 2006, In : Journal of Cell Science. 119, Pt. 12, p. 2572 - 2582 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
26 Citations (Scopus)

Caspase-2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase-7

Ho, P. K., Jabbour, A., Ekert, P. G. & Hawkins, C. J., 2005, In : FEBS Journal. 272, 6, p. 1401 - 1414 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2004
11 Citations (Scopus)

The Caenorhabditis elegans CED-9 protein does not directly inhibit the caspase CED-3, in vitro nor in yeast

Jabbour, A., Ho, P. K., Puryer, M. A., Ashley, D. M., Ekert, P. G. & Hawkins, C. J., 2004, In : Cell Death and Differentiation. 11, 12, p. 1309 - 1316 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

The p35 family of apoptosis inhibitors

Jabbour, A. & Hawkins, C. J., 2004, In : Current Genomics. 5, 3, p. 215 - 229 15 p.

Research output: Contribution to journalArticleResearchpeer-review