Projects per year
Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
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Positive allosteric modulation of anti-convulsant G protein-coupled receptor signalling to treat drug-resistant epilepsy
May, L., Webb, G., Carlsson, J., Baltos, J., Nguyen, A., Christopoulos, A., Miao, Y., O'Brien, T., Rollo, B., Casillas-Espinosa, P., Gregory, K., Scammells, P. & Nguyen, T.
1/01/22 → 31/12/25
Project: Research
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Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A1Receptor in Living Cells
Comeo, E., Trinh, P., Nguyen, A. T., Nowell, C. J., Kindon, N. D., Soave, M., Stoddart, L. A., White, J. M., Hill, S. J., Kellam, B., Halls, M. L., May, L. T. & Scammells, P. J., 16 Mar 2021, In: Journal of Medicinal Chemistry. 64, 10, p. 6670–6695 26 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia
Draper-Joyce, C. J., Bhola, R., Wang, J., Bhattarai, A., Nguyen, A. T. N., Cowie-Kent, I., O’Sullivan, K., Chia, L. Y., Venugopal, H., Valant, C., Thal, D. M., Wootten, D., Panel, N., Carlsson, J., Christie, M. J., White, P. J., Scammells, P., May, L. T., Sexton, P. M., Danev, R. & 4 others, , 23 Sep 2021, In: Nature. 597, p. 571–576 25 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access9 Citations (Scopus) -
A Structure-Activity Relationship Study of Bitopic N 6-Substituted Adenosine Derivatives as Biased Adenosine A1 Receptor Agonists
Aurelio, L., Baltos, J. A., Ford, L., Nguyen, A. T. N., Jörg, M., Devine, S. M., Valant, C., White, P. J., Christopoulos, A., May, L. T. & Scammells, P. J., 8 Mar 2018, In: Journal of Medicinal Chemistry. 61, 5, p. 2087-2103 17 p.Research output: Contribution to journal › Article › Research › peer-review
17 Citations (Scopus) -
New paradigms in adenosine receptor pharmacology: allostery, oligomerization and biased agonism
Vecchio, E. A., Baltos, J. A., Nguyen, A. T. N., Christopoulos, A., White, P. J. & May, L. T., 1 Nov 2018, In: British Journal of Pharmacology. 175, 21, p. 4036-4046 11 p.Research output: Contribution to journal › Review Article › Research › peer-review
26 Citations (Scopus) -
Structural Basis for Binding of Allosteric Drug Leads in the Adenosine A1 Receptor
Miao, Y., Bhattarai, A., Nguyen, A. T. N., Christopoulos, A. & May, L. T., 1 Dec 2018, In: Scientific Reports. 8, 1, 13 p., 16836.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile24 Citations (Scopus)