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Research Output 2002 2019

2019

pH-Responsive Polymer Nanoparticles for Drug Delivery

Deirram, N., Zhang, C., Kermaniyan, S. S., Johnston, A. P. R. & Such, G. K., 1 May 2019, In : Macromolecular Rapid Communications. 40, 10, 23 p., 1800917.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Pointing in the right direction: Controlling the orientation of proteins on nanoparticles improves targeting efficiency

Yong, K. W., Yuen, D., Chen, M. Z., Porter, C. J. H. & Johnston, A. P. R., 13 Mar 2019, In : Nano Letters. 19, 3, p. 1827−1831 5 p.

Research output: Contribution to journalArticleResearchpeer-review

The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery

Smith, S. A., Selby, L. I., Johnston, A. P. R. & Such, G. K., 20 Feb 2019, In : Bioconjugate Chemistry. 30, 2, p. 263-272 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2018

Clickable Cubosomes for Antibody-Free Drug Targeting and Imaging Applications

Alcaraz, N., Liu, Q., Hanssen, E., Johnston, A. & Boyd, B. J., 17 Jan 2018, In : Bioconjugate Chemistry. 29, 1, p. 149-157 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Distribution of therapeutic proteins into thoracic lymph after intravenous administration is protein size-dependent and primarily occurs within the liver and mesentery

Yadav, P., McLeod, V. M., Nowell, C. J., Selby, L. I., Johnston, A. P. R., Kaminskas, L. M. & Trevaskis, N. L., 28 Feb 2018, In : Journal of Controlled Release. 272, p. 17-28 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Elucidating the Influences of Size, Surface Chemistry, and Dynamic Flow on Cellular Association of Nanoparticles Made by Polymerization-Induced Self-Assembly

Khor, S. Y., Vu, M. N., Pilkington, E. H., Johnston, A. P. R., Whittaker, M. R., Quinn, J. F., Truong, N. P. & Davis, T. P., 23 Aug 2018, In : Small. 14, 34, 13 p., 1801702.

Research output: Contribution to journalArticleResearchpeer-review

How to do things with metaphors: engineering life as hodgepodge

Kearnes, M., Kuch, D. & Johnston, A., 17 Sep 2018, In : Life Sciences, Society and Policy. 14, 1, 17 p., 22.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
File

Journey to the centre of the cell: Virtual reality immersion into scientific data

Johnston, A. P. R., Rae, J., Ariotti, N., Bailey, B., Lilja, A., Webb, R., Ferguson, C., Maher, S., Davis, T. P., Webb, R. I., McGhee, J. & Parton, R. G., 1 Feb 2018, In : Traffic. 19, 2, p. 105-110 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Minimum information reporting in bio–nano experimental literature

Faria, M., Björnmalm, M., Thurecht, K. J., Kent, S. J., Parton, R. G., Kavallaris, M., Johnston, A. P. R., Gooding, J. J., Corrie, S. R., Boyd, B. J., Thordarson, P., Whittaker, A. K., Stevens, M. M., Prestidge, C. A., Porter, C. J. H., Parak, W. J., Davis, T. P., Crampin, E. J. & Caruso, F., 1 Sep 2018, In : Nature Nanotechnology. 13, 9, p. 777-785 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Quantifying cellular internalization with a fluorescent click sensor

Selby, L. I., Aurelio, L., Yuen, D., Graham, B. & Johnston, A. P. R., 22 Jun 2018, In : ACS Sensors. 3, 6, p. 1182-1189 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Secondary Self-Assembly of Supramolecular Nanotubes into Tubisomes and Their Activity on Cells

Brendel, J. C., Sanchis, J., Catrouillet, S., Czuba, E., Chen, M. Z., Long, B. M., Nowell, C., Johnston, A., Jolliffe, K. A. & Perrier, S., 17 Dec 2018, In : Angewandte Chemie - International Edition. 57, 51, p. 16678-16682 5 p.

Research output: Contribution to journalArticleResearchpeer-review

The potential of nanoparticle vaccines as a treatment for cancer

Urbanavicius, D., Alvarez, T., Such, G. K., Johnston, A. P. R. & Mintern, J. D., 1 Jun 2018, In : Molecular Immunology. 98, p. 2-7 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2017

Antibody-dependent phagocytosis (ADP) responses following trivalent inactivated influenza vaccination of younger and older adults

Ana-Sosa-Batiz, F., Johnston, A. P. R., Hogarth, P. M., Wines, B. D., Barr, I., Wheatley, A. K. & Kent, S. J., Nov 2017, In : Vaccine. 35, 47, p. 6451-6458 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Antibody-mediated targeting of antigen to C-type lectin-like receptors Clec9A and Clec12A elicits different vaccination outcomes

Macri, C., Dumont, C., Panozza, S., Lahoud, M. H., Caminschi, I., Villadangos, J. A., Johnston, A. P. R. & Mintern, J. D., Jan 2017, In : Molecular Immunology. 81, p. 143-150 8 p.

Research output: Contribution to journalArticleResearchpeer-review

DNA-based probes for flow cytometry analysis of endocytosis and recycling

Dumont, C. F. M., Czuba, E., Chen, M., Villadangos, J. A., Johnston, A. P. R. & Mintern, J. D., 1 Apr 2017, In : Traffic. 18, 4, p. 242-249 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Life under the Microscope: Quantifying Live Cell Interactions to Improve Nanoscale Drug Delivery

Johnston, A. P. R., 27 Jan 2017, In : ACS Sensors. 2, 1, p. 4-9 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Nanoescapology: progress toward understanding the endosomal escape of polymeric nanoparticles

Selby, L. I., Cortez-Jugo, C. M., Such, G. K. & Johnston, A. P. R., 1 Sep 2017, In : Wiley Interdisciplinary Reviews:Nanomedicine and Nanobiotechnology. 9, 5, 23 p., e1452.

Research output: Contribution to journalReview ArticleResearchpeer-review

pH-Responsive Transferrin-pHlexi particles capable of targeting cells in vitro

Wong, A. S. M., Czuba, E., Chen, M. Z., Yuen, D., Cupic, K. I., Yang, S., Hodgetts, R. Y., Selby, L. I., Johnston, A. P. R. & Such, G. K., 2017, In : ACS Macro Letters. 6, 3, p. 315-320 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Probing Endosomal Escape Using pHlexi Nanoparticles

Kongkatigumjorn, N., Cortez-Jugo, C., Czuba, E., Wong, A. S. M., Hodgetts, R. Y., Johnston, A. P. R. & Such, G. K., 1 Apr 2017, In : Macromolecular Bioscience. 17, 4, 11 p., 1600248.

Research output: Contribution to journalArticleResearchpeer-review

Thiol-Reactive Star Polymers Display Enhanced Association with Distinct Human Blood Components

Glass, J. J., Li, Y., De Rose, R., Johnston, A., Czuba, E. I., Khor, S. Y., Quinn, J. F., Whittaker, M. R., Davis, T. P. & Kent, S. J., 12 Apr 2017, In : ACS Applied Materials and Interfaces. 9, 14, p. 12182-12194 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

Analysis of intracellular trafficking of dendritic cell receptors for antigen targeting

Liu, H., Dumont, C., Johnston, A. P. R. & Mintern, J. D., 2016, Dendritic Cell Protocols. Segura, E. & Onai, N. (eds.). 3rd ed. New York NY USA: Humana Press, Vol. 1423. p. 199-209 11 p. (Methods in Molecular Biology; vol. 1423).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Flow Cytometry: HD Flow Cytometry: An Improved Way to Quantify Cellular Interactions with Nanoparticles (Adv. Healthcare Mater. 18/2016)

Selby, L. I., Kongkatigumjorn, N., Such, G. K. & Johnston, A. P. R., 21 Sep 2016, In : Advanced Healthcare Materials. 5, 18, p. 2332 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

HD Flow Cytometry: An Improved Way to Quantify Cellular Interactions with Nanoparticles

Selby, L. I., Kongkatigumjorn, N., Such, G. K. & Johnston, A. P. R., 21 Sep 2016, In : Advanced Healthcare Materials. 5, 18, p. 2333-2338 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Human immune cell targeting of protein nanoparticles - caveospheres

Glass, J. J., Yuen, D. M. T., Rae, J. A., Johnston, A., Parton, R. G., Kent, S. J. & De Rose, R., 2016, In : Nanoscale. 8, 15, p. 8255 - 8265 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Influenza-specific antibody-dependent phagocytosis

Ana-Sosa-Batiz, F., Vanderven, H., Jegaskanda, S., Johnston, A., Rockman, S., Laurie, K. L., Barr, I. G., Reading, P. C., Lichtfuss, M. & Kent, S. J., 2016, In : PLoS ONE. 11, 4, p. 1 - 18 18 p., e0154461.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Journey to the Centre of the cell (JTCC): A 3D VR experience derived from migratory breast cancer cell image data

McGhee, J., Bailey, B., Parton, R. G., Ariotti, N. & Johnston, A., 28 Nov 2016, Proceeding SA 2016 - SIGGRAPH ASIA 2016 VR Showcase. Liu, E. & Miguel de Joya, J. (eds.). New York NY USA: Association for Computing Machinery (ACM), 11

Research output: Chapter in Book/Report/Conference proceedingConference PaperOtherpeer-review

Quantifying nanoparticle internalization using a high throughput internalization assay

Mann, S. K., Czuba, E., Selby, L. I., Such, G. K. & Johnston, A. P. R., 1 Oct 2016, In : Pharmaceutical Research. 33, 10, p. 2421-2432 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Targeting dendritic cells: A promising strategy to improve vaccine effectiveness

Macri, C., Dumont, C., Johnston, A. PR. & Mintern, J., 18 Mar 2016, In : Clinical and Translational Immunology. 5, 3, 8 p., e66.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
File

Tuning the properties of pH responsive nanoparticles to control cellular interactions in vitro and ex vivo

Mann, S. K., Dufour, A., Glass, J. J., De Rose, R., Kent, S. J., Such, G. K. & Johnston, A. P. R., 14 Oct 2016, In : Polymer Chemistry. 7, 38, p. 6015-6024 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2015

Criteria for dendritic cell receptor selection for efficient antibody-targeted vaccination

Reuter, A., Panozza, S. E., Macri, C., Dumont, C., Li, J., Liu, H., Segura, E., Vega-Ramos, J., Gupta, N., Caminschi, I., Villadangos, J. A., Johnston, A. P. R. & Mintern, J. D., 2015, In : Journal of Immunology. 194, 6, p. 2696-2705 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential use of autophagy by primary dendritic cells specialized in cross-presentation

Mintern, J. D., Macri, C., Chin, W. J., Panozza, S. E., Segura, E., Patterson, N. L., Zeller, P., Bourges, D., Bedoui, S., McMillan, P., Idris, A., Nowell, C. J., Brown, A., Radford, K. J., Johnston, A. & Villadangos, J. A., 2015, In : Autophagy. 11, 6, p. 906-917 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Interfacing materials science and biology for drug carrier design

Such, G. K., Yan, Y., Johnston, A. P. R., Gunawan, S. T. & Caruso, F., 2015, In : Advanced Materials. 27, 14, p. 2278-2297 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Organic arsenicals as efficient and highly specific linkers for protein/peptide-polymer conjugation

Wilson, P. J., Anastasaki, A., Owen, M. R., Kempe, K., Haddleton, D. M., Mann, S., Johnston, A., Quinn, J., Whittaker, M. R., Hogg, P. J. & Davis, T. P., 2015, In : Journal of the American Chemical Society. 137, 12, p. 4215 - 4222 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Particle generation, functionalization and sortase A-mediated modification with targeting of single-chain antibodies for diagnostic and therapeutic use

Hagemeyer, C. E., Alt, K. M., Johnston, A., Such, G. K., Ta, H. T., Leung, M. K. M., Prabhu, S., Wang, X., Caruso, F. & Peter, K., 2015, In : Nature Protocols. 10, 1, p. 90 - 105 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Self-assembling dual component nanoparticles with endosomal escape capability

Wong, A. S. M., Mann, S., Czuba, E. I., Sahut, A., Liu, H., Suekama, T. C., Bickerton, T. L., Johnston, A. & Such, G. K., 2015, In : Soft Matter. 11, 15, p. 2993-3002 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2014

Endocytic pH-triggered degradation of nanoengineered multilayer capsules

Liang, K., Such, G. K., Johnston, A., Zhu, Z., Ejima, H., Richardson, J. J., Cui, J. & Caruso, F., 2014, In : Advanced Materials. 26, 12, p. 1901 - 1905 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Engineering enzyme-cleavable hybrid click capsules with a pH-sheddable coating for intracellular degradation

Gunawan, S. T., Liang, K., Such, G. K., Johnston, A., Leung, M. K. M., Cui, J. & Caruso, F., 29 Oct 2014, In : Small. 10, 20, p. 4080 - 4086 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Fluorescent nanosensors for intracellular measurements: Synthesis, characterization, calibration, and measurement

Desai, A. S., Chauhan, V. M., Johnston, A. P. R., Esler, T. & Aylott, J. W., 16 Jan 2014, In : Frontiers in Physiology. 4, 1, 15 p., 401.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Fundamental studies of hybrid poly(2-(diisopropylamino)ethyl methacrylate)/poly(N-vinylpyrrolidone) films and capsules

Ng, S. L., Best, J. P., Kempe, K., Liang, K., Johnston, A., Such, G. K. & Caruso, F., 2014, In : Biomacromolecules. 15, 7, p. 2784-2792 9 p.

Research output: Contribution to journalArticleResearchpeer-review

HIV-specific antibody-dependent phagocytosis matures during HIV infection

Ana-Sosa-Batiz, F., Johnston, A., Liu, H., Center, R. J., Rerks-Ngarm, S., Pitisuttithum, P., Nitayaphan, S., Kaewkungwal, J., Kim, J. H., Michael, N. L., Kelleher, A. D., Stratov, I., Kent, S. J. & Kramski, M., 2014, In : Immunology and Cell Biology. 92, 8, p. 679 - 687 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Programmed degradation of DNA multilayer films

Lee, L., Johnston, A. & Caruso, F., 23 Jul 2014, In : Small. 10, 14, p. 2902-2909 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Tuning particle biodegradation through polymer-peptide blend composition

Gunawan, S. T., Kempe, K., Such, G. K., Cui, J., Liang, K., Richardson, J. J., Johnston, A. P. R. & Caruso, F., 8 Dec 2014, In : Biomacromolecules. 15, 12, p. 4429-4438 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

A programmable sensor to probe the internalization of proteins and nanoparticles in live cells

Liu, H. & Johnston, A., 2013, In : Angewandte Chemie - International Edition. 52, 22, p. 5744 - 5748 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Mechanically tunable, self-adjuvanting nanoengineered polypeptide particles

Cui, J., De Rose, R., Best, J. P., Johnston, A., Alcantara, S., Liang, K., Such, G. K., Kent, S. J. & Caruso, F., 2013, In : Advanced Materials. 25, 25, p. 3468 - 3472 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

Lopez, J., Susanto, O., Jenkins, M., Lukoyanova, N., Sutton, V. R., Law, R. H. P., Johnston, A., Bird, C. H., Bird, P. I., Whisstock, J., Trapani, J. A., Saibil, H. & Voskoboinik, I., 2013, In : Blood. 121, 14, p. 2659 - 2668 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Targeting dendritic cells: The role of specific receptors in the internalization of polymer capsules

Mintern, J., Percival, C. S., Kamphuis, M. MJ., Chin, W. J., Caruso, F. & Johnston, A., 2013, In : Advanced Healthcare Materials. 2, 7, p. 940 - 944 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

Bio-click chemistry: enzymatic functionalization of PEGylated capsules for targeting applications

Leung, M. K. M., Hagemeyer, C. E., Johnston, A. P. R., Gonzales, C., Kamphuis, M. MJ., Ardipradja, K., Such, G. K., Peter, K. & Caruso, F., 2012, In : Angewandte Chemie - International Edition. 51, 29, p. 7132 - 7136 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Engineered bacterially expressed polypeptides: Assembly into polymer particles with tailored degradation profiles

Chang, D. H. C., Johnston, A. P. R., Wark, K. L., Breheney, K. & Caruso, F., 9 Jan 2012, In : Angewandte Chemie - International Edition. 51, 2, p. 460-464 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Engineered Layer-by-Layer Assembled Capsules for Biomedical Applications

Johnston, A. P. R., Such, G. K., Dodds, S. J. & Caruso, F., 21 May 2012, Multilayer Thin Films: Sequential Assembly of Nanocomposite Materials. Decher, G. & Schlenoff, J. B. (eds.). 2nd ed. Weinheim Germany: Wiley-VCH Verlag GmbH & Co. KGaA, p. 801-829 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Engineering cellular degradation of multilayered capsules through controlled cross-linking

Liang, K., Such, G. K., Zhu, Z., Dodds, S. J., Johnston, A., Cui, J., Ejima, H. & Caruso, F., 2012, In : ACS Nano. 6, 11, p. 10186 - 10194 9 p.

Research output: Contribution to journalArticleResearchpeer-review