Projects per year
Personal profile
Biography
Dr Angus Johnston is an ARC Future Fellow who's work focuses on developing better ways to deliver drugs, making them more therapeutically active and limiting side effects. He has extensive knowledge and expertise in nanomaterials assembly, material characterisation, cellular interactions and advanced imaging techniques.
His group is interested in understanding how nanoengineered materials interact with biological systems. This work involves developing molecular sensors to determine the internalisation, trafficking and local environment that nanoparticles are exposed to in living cells. With a better understudying of how these material interact with cells, we can engineer smarter materials for improved drug and vaccine delivery.
For more information, visit the NanoMaterials for Biology group website - www.nanomb.org
Related Links:
Research interests
-Targeted Vaccine Therapy
-Sensors for Cellular Imaging
-Understanding Cellular Processing of Nanoparticles
-Self assembling peptides as drug carriers
-Toxicology of Nanomaterials
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- nanomaterials assembly
- material characterisation
- cellular interactions
- advanced imaging
Collaborations and top research areas from the last five years
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Protein engineering approaches to next generation targeting agents
Porter, C., Johnston, A., Owen, D. J. & Yuen, D.
1/04/17 → 31/03/20
Project: Research
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A structure-based design approach to maximising targeting interactions
Porter, C., Johnston, A., Scanlon, M. & Owen, D. J.
1/07/20 → 30/06/23
Project: Research
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Development of novel mRNA products for clinical trials
Pouton, C., Beilharz, T., Carroll, J., Porter, C., Al-Wassiti, H., Davidovich, C., Johnston, A. & Trevaskis, N.
10/05/23 → 2/10/28
Project: Research
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The Victorian Pre-clinical mRNA Innovation Incubator (VPMII)
Porter, C., Pouton, C., Carroll, J., Beilharz, T., Purcell, D. F. J., Caruso, F., Trevaskis, N., Johnston, A., Davidovich, C. & Knott, G.
23/06/22 → 22/06/25
Project: Research
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The role of hyaluronan in antigen and immune cell trafficking
Porter, C., Mintern, J. D., Johnston, A., Feeney, O. & Hays Putnam, A.
1/05/22 → 30/04/25
Project: Research
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Association of a vaccine adjuvant with endogenous HDL increases lymph uptake and dendritic cell activation
Gracia, G., Cao, E., Kochappan, R., Porter, C. J. H., Johnston, A. P. R. & Trevaskis, N. L., Mar 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 172, p. 240-252 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Microencapsulation-based cell therapies
Marikar, S. N., El-Osta, A., Johnston, A., Such, G. & Al-Hasani, K., Jul 2022, In: Cellular and Molecular Life Sciences. 79, 7, 13 p., 351.Research output: Contribution to journal › Review Article › Other › peer-review
Open Access3 Citations (Scopus) -
Nanoparticles for vaccine and gene therapy: Overcoming the barriers to nucleic acid delivery
Molle, L., Smyth, C., Yuen, D. & Johnston, A. P. R., Nov 2022, In: WIREs Nanomedicine and Nanobiotechnology. 14, 6, 38 p., e1809.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access5 Citations (Scopus) -
Quantifying the Endosomal Escape of pH-Responsive Nanoparticles Using the Split Luciferase Endosomal Escape Quantification Assay
Beach, M. A., Teo, S. L. Y., Chen, M. Z., Smith, S. A., Pouton, C. W., Johnston, A. P. R. & Such, G. K., 26 Jan 2022, In: ACS Applied Materials & Interfaces. 14, 3, p. 3653-3661 9 p.Research output: Contribution to journal › Article › Research › peer-review
13 Citations (Scopus) -
Resolving subcellular pH with a quantitative fluorescent lifetime biosensor
Rennick, J. J., Nowell, C. J., Pouton, C. W. & Johnston, A. P. R., Dec 2022, In: Nature Communications. 13, 1, 13 p., 6023.Research output: Contribution to journal › Article › Research › peer-review
Open Access4 Citations (Scopus)