Projects per year
Personal profile
Biography
Dr Angus Johnston is an ARC Future Fellow who's work focuses on developing better ways to deliver drugs, making them more therapeutically active and limiting side effects. He has extensive knowledge and expertise in nanomaterials assembly, material characterisation, cellular interactions and advanced imaging techniques.
His group is interested in understanding how nanoengineered materials interact with biological systems. This work involves developing molecular sensors to determine the internalisation, trafficking and local environment that nanoparticles are exposed to in living cells. With a better understudying of how these material interact with cells, we can engineer smarter materials for improved drug and vaccine delivery.
For more information, visit the NanoMaterials for Biology group website - www.nanomb.org
Related Links:
Research interests
-Targeted Vaccine Therapy
-Sensors for Cellular Imaging
-Understanding Cellular Processing of Nanoparticles
-Self assembling peptides as drug carriers
-Toxicology of Nanomaterials
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- nanomaterials assembly
- material characterisation
- cellular interactions
- advanced imaging
Network
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Protein engineering approaches to next generation targeting agents
Porter, C., Johnston, A., Owen, D. J. & Yuen, D.
1/04/17 → 31/03/20
Project: Research
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A structure-based design approach to maximising targeting interactions
Porter, C., Johnston, A., Scanlon, M. & Owen, D. J.
29/04/21 → 29/04/24
Project: Research
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The role of hyaluronan in antigen and immune cell trafficking
Porter, C., Mintern, J. D., Johnston, A., Feeney, O. & Hays Putnam, A.
29/03/22 → 28/03/24
Project: Research
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Improving therapeutic delivery of RNA
Johnston, A., Such, G. K., Pouton, C., Mintern, J. D. & Sloan, E.
1/01/22 → 31/12/24
Project: Research
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Caveospheres: A versatile peptide delivery system
Johnston, A., Veldhuis, N., Poole, D. & Foley, M. A.
15/09/20 → 14/09/23
Project: Research
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Association of a vaccine adjuvant with endogenous HDL increases lymph uptake and dendritic cell activation
Gracia, G., Cao, E., Kochappan, R., Porter, C. J. H., Johnston, A. P. R. & Trevaskis, N. L., Mar 2022, In: European Journal of Pharmaceutics and Biopharmaceutics. 172, p. 240-252 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Adenovirus terminal protein contains a bipartite nuclear localisation signal essential for its import into the nucleus
Al-Wassiti, H. A., Thomas, D. R., Wagstaff, K. M., Fabb, S. A., Jans, D. A., Johnston, A. P. & Pouton, C. W., 1 Apr 2021, In: International Journal of Molecular Sciences. 22, 7, 18 p., 3310.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus) -
Inducing immune tolerance with dendritic cell-targeting nanomedicines
Cifuentes-Rius, A., Desai, A., Yuen, D., Johnston, A. P. R. & Voelcker, N. H., 2021, In: Nature Nanotechnology. 16, 1, p. 37–46 10 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access47 Citations (Scopus) -
In Vivo Quantification of Nanoparticle Association with Immune Cell Subsets in Blood
Ong, Y. R., De Rose, R. & Johnston, A. P. R., 5 May 2021, In: Advanced Healthcare Materials. 10, 9, 8 p., 2002160.Research output: Contribution to journal › Article › Research › peer-review
3 Citations (Scopus) -
It's what's on the inside that counts: Techniques for investigating the uptake and recycling of nanoparticles and proteins in cells
FitzGerald, L. I. & Johnston, A. P. R., Apr 2021, In: Journal of Colloid and Interface Science. 587, p. 64-78 15 p.Research output: Contribution to journal › Review Article › Other › peer-review
15 Citations (Scopus)