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Personal profile

Biography

Dr Angus Johnston is an ARC Future Fellow who's work focuses on developing better ways to deliver drugs, making them more therapeutically active and limiting side effects. He has extensive knowledge and expertise in nanomaterials assembly, material characterisation, cellular interactions and advanced imaging techniques.

His group is interested in understanding how nanoengineered materials interact with biological systems. This work involves developing molecular sensors to determine the internalisation, trafficking and local environment that nanoparticles are exposed to in living cells. With a better understudying of how these material interact with cells, we can engineer smarter materials for improved drug and vaccine delivery.

For more information, visit the NanoMaterials for Biology group website - www.nanomb.org

Related Links:

Research interests


-Targeted Vaccine Therapy
-Sensors for Cellular Imaging
-Understanding Cellular Processing of Nanoparticles
-Self assembling peptides as drug carriers
-Toxicology of Nanomaterials

Keywords

  • nanomaterials assembly
  • material characterisation
  • cellular interactions
  • advanced imaging

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2021

Protein engineering approaches to next generation targeting agents

Porter, C., Johnston, A., Owen, D. J. & Yuen, D.

1/04/1731/03/20

Project: Research

ARC Centre of Excellence in Convergent Bio-Nano Science and Technology

Davis, T., Boyd, B., Bunnett, N., Caruso, F., Corrie, S. R., Crampin, E., Gooding, J., Johnston, A., Kavallaris, M., Kearnes, M., Kent, S., McGhee, J., Nann, T., Parton, R., Porter, C., Thordarson, P., Thurecht, K., Voelcker, N. H., Whittaker, A., Abbott, N., Alexander, C., Dawson, K., Greguric, I., Haddleton, D., Hawker, C., Lee, D. S., Lewis, J., McLean, K., Stevens, M., Jones-Jayasinghe, N., Thierry, B. & Prestidge, C. A.

Australian Research Council (ARC), Memorial Sloan Kettering Cancer Center, The University of Nottingham (UK), University College Dublin, University of California , University of Warwick, University of Wisconsin-Madison, SungKyunKwan University, Monash University, The University of Melbourne, The University of New South Wales, The University of Queensland , University of South Australia, Australian Nuclear Science and Technology Organisation , CSIRO Materials Science and Engineering (CMSE), Imperial College London

30/06/1429/06/21

Project: Research

Nano-Bioscience Imaging Facility

Caruso, F., Davis, T., Kent, S. J., Porter, C., Johnston, A., Qiao, G., Sexton, P., Crampin, E. J., Boyd, B., Cavalieri, F. & Hodgkin, P. D.

Project: Other

Research Output 2002 2019

pH-Responsive Polymer Nanoparticles for Drug Delivery

Deirram, N., Zhang, C., Kermaniyan, S. S., Johnston, A. P. R. & Such, G. K., 1 May 2019, In : Macromolecular Rapid Communications. 40, 10, 23 p., 1800917.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File

Pointing in the right direction: Controlling the orientation of proteins on nanoparticles improves targeting efficiency

Yong, K. W., Yuen, D., Chen, M. Z., Porter, C. J. H. & Johnston, A. P. R., 13 Mar 2019, In : Nano Letters. 19, 3, p. 1827−1831 5 p.

Research output: Contribution to journalArticleResearchpeer-review

The Endosomal Escape of Nanoparticles: Toward More Efficient Cellular Delivery

Smith, S. A., Selby, L. I., Johnston, A. P. R. & Such, G. K., 20 Feb 2019, In : Bioconjugate Chemistry. 30, 2, p. 263-272 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Clickable Cubosomes for Antibody-Free Drug Targeting and Imaging Applications

Alcaraz, N., Liu, Q., Hanssen, E., Johnston, A. & Boyd, B. J., 17 Jan 2018, In : Bioconjugate Chemistry. 29, 1, p. 149-157 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Distribution of therapeutic proteins into thoracic lymph after intravenous administration is protein size-dependent and primarily occurs within the liver and mesentery

Yadav, P., McLeod, V. M., Nowell, C. J., Selby, L. I., Johnston, A. P. R., Kaminskas, L. M. & Trevaskis, N. L., 28 Feb 2018, In : Journal of Controlled Release. 272, p. 17-28 12 p.

Research output: Contribution to journalArticleResearchpeer-review