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Research Output 1999 2019

2019

Targeting XIAP and PPARγ in granulosa cell tumors alters metabolic signaling

Leung, T. H., Rainczuk, A., Nguyen, T., Stephens, A., Silke, J., Fuller, P. J. & Chu, S., 5 Apr 2019, In : Journal of Proteome Research. 18, 4, p. 1691-1701 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Autoantibodies against HSF1 and CCDC155 as biomarkers of early-Stage, high-Grade serous ovarian cancer

Wilson, A. L., Moffitt, L. R., Duffield, N., Rainczuk, A., Jobling, T. W., Plebanski, M. & Stephens, A. N., 1 Feb 2018, In : Cancer Epidemiology Biomarkers and Prevention. 27, 2, p. 183-192 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine

Sandow, J. J., Rainczuk, A., Infusini, G., Makanji, M., Bilandzic, M., Wilson, A. L., Fairweather, N., Stanton, P. G., Garama, D., Gough, D., Jobling, T. W., Webb, A. I. & Stephens, A. N., 1 May 2018, In : Proteomics - Clinical Applications. 12, 3, 10 p., 1700135.

Research output: Contribution to journalArticleResearchpeer-review

Immunotherapeutic Interleukin-6 or Interleukin-6 Receptor Blockade in Cancer: Challenges and Opportunities

Kampan, N. C., Xiang, S. D., McNally, O. M., Stephens, A. N., Quinn, M. A. & Plebanski, M., 1 Jan 2018, In : Current Medicinal Chemistry. 25, 36, p. 4785-4806 22 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Sperm protein 17 expression by murine epithelial ovarian cancer cells and its impact on tumor progression

Gao, Q., Xiang, S. D., Wilson, K., Madondo, M., Stephens, A. N. & Plebanski, M., 20 Aug 2018, In : Cancers. 10, 8, 15 p., 276.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2017

Erratum to: Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors. [Genome Med. 7 (2015) (87)]

Ryland, G. L., Hunter, S. M., Doyle, M. A., Caramia, F., Li, J., Rowley, S. M., Christie, M., Allan, P. E., Stephens, A. N., Bowtell, D. D. L., Campbell, I. G. & Gorringe, K. L., 12 Jan 2017, In : Genome Medicine: medicine in the post-genomic era. 9, 1, 1.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Interleukin 6 Present in inflammatory ascites from advanced epithelial ovarian cancer patients promotes tumor necrosis factor receptor 2-expressing regulatory T cells

Kampan, N. C., Madondo, M. T., McNally, O. M., Stephens, A. N., Quinn, M. A. & Plebanski, M., 6 Nov 2017, In : Frontiers in Immunology. 8, NOV, 14 p., 1482.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

New Trends in Anti-Cancer Therapy: Combining Conventional Chemotherapeutics with Novel Immunomodulators

Wilson, A. L., Plebanski, M. & Stephens, A., 29 Aug 2017, (Accepted/In press) In : Current Medicinal Chemistry. 27 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2016

Mapping the testicular interstitial fluid proteome from normal rats

Stanton, P. G., Foo, C. FH., Rainczuk, A., Stephens, A. N., Condina, M., O'Donnell, L., Weidner, W., Ishikawa, T., Cruickshanks, L., Smith, L. B. & McLachlan, R. I., 1 Sep 2016, In : Proteomics. 16, 17, p. 2391-2402 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Measuring PC activity in endocervical swab may provide a simple and non-invasive method to detect endometrial cancer in post-menopausal women

Heng, S., Stephens, A. N., Jobling, T. W. & Nie, G., 25 Jun 2016, In : Oncotarget. 7, 29, p. 46573-46578 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Total PC activity is increased in uterine lavage of post-menopausal endometrial but not ovarian cancer patients

Heng, S., Stephens, A. N., Jobling, T. & Nie, G-Y., 2016, In : Journal of Cancer. 7, 13, p. 1812 - 1814 3 p.

Research output: Contribution to journalArticleOtherpeer-review

2015

Identification of novel dipeptidyl peptidase 9 substrates by two-dimensional differential in-gel electrophoresis

Zhang, H., Maqsudi, S., Rainczuk, A., Duffield, N., Lawrence, J. M., Keane, F. M., Justa-Schuch, D., Geiss-Friedlander, R., Gorrell, M. D. & Stephens, A., 2015, In : FEBS Journal. 282, 19, p. 3737 - 3757 21 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes

Hunter, S. M., Anglesio, M. S., Ryland, G. L., Sharma, R., Chiew, Y. E., Rowley, S. M., Doyle, M. A., Li, J., Gilks, C. B., Moss, P., Allan, P. E., Stephens, A., Huntsman, D. G., DeFazio, A., Bowtell, D. D. L., Gorringe, K. L. & Campbell, I. G., 2015, In : Oncotarget. 6, 35, p. 37663 - 37677 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

Ryland, G. L., Hunter, S. M., Doyle, M. A., Caramia, F., Li, J., Rowley, S. M., Christie, M., Allan, P. E., Stephens, A., Bowtell, D. D. L., Campbell, I. G. & Gorringe, K. L., 2015, In : Genome Medicine: medicine in the post-genomic era. 7, 1, 12 p., 87.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2014

EPO-receptor is present in mouse C2C12 and human primary skeletal muscle cells but EPO does not influence myogenesis

Lamon, S., Zacharewicz, E., Stephens, A. N. & Russell, A. P., 2014, In : Physiological Reports. 2, 3, e00256.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Evidence for the antagonistic form of CXC-motif chemokine CXCL10 in serous epithelial ovarian tumours

Rainczuk, A., Rao, J. R., Gathercole, J. L., Fairweather, N. J., Chu, S., Masadah, R., Jobling, T. W., Deb-Choudhury, S., Dyer, J. & Stephens, A. N., 2014, In : International Journal of Cancer. 134, 3, p. 530-541 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

Htra3 is downregulated in cancer cell lines and significantly reduced in primary serous and granulosa cell ovarian tumors

Singh, H., Li, Y., Fuller, P. J., Harrison, C., Rao, J., Stephens, A. N. & Nie, G-Y., 2013, In : Journal of Cancer. 4, 2, p. 152-164 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Proteomics of the human endometrium and uterine fluid: a pathway to biomarker discovery

Salamonsen, L. A., Edgell, T., Rombauts, L., Stephens, A. N., Robertson, D., Rainczuk, A., Nie, G. & Hannan, N. J., 2013, In : Fertility and Sterility. 99, 4, p. 1086 - 1092 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The utility of isotope-coded protein labeling for prioritization of proteins found in ovarian cancer patient urine

Rainczuk, A., Condina, M., Pelzing, M., Dolman, S., Rao, J., Fairweather, N., Jobling, T. & Stephens, A. N., 6 Sep 2013, In : Journal of Proteome Research. 12, 9, p. 4074-4088 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2012

Application of the wheat-germ cell-free translation system to produce high temperature requirement A3 (HtrA3) proteases

Singh, H., Makino, S., Endo, Y., Li, Y., Stephens, A. N. & Nie, G., Jan 2012, In : BioTechniques. 52, 1, p. 23-28 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Decidual-secreted factors alter invasive trophoblast membrane and secreted proteins implying a role for decidual cell regulation of placentation

Menkhorst, E. M., Lane, N., Winship, A. L., Li, P., Yap, J., Meehan, K., Rainczuk, A., Stephens, A. & Dimitriadis, E., 16 Feb 2012, In : PLoS ONE. 7, 2, 11 p., e31418.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Diagnosis of Endometriosis: Proteomics

Stephens, A. N., Rombauts, L. J. F. & Salamonsen, L. A., 25 Jan 2012, Endometriosis: Science and Practice. Giudice, L. C., Evers, J. L. H. & Healy, D. L. (eds.). West Essex UK: Wiley-Blackwell, p. 324-335 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Proteomic changes in rat spermatogenesis in response to in vivo androgen manipulation; impact on meiotic cells

Stanton, P. G., Sluka, P., Foo, C. FH., Stephens, A. N., Smith, A. I., McLachlan, R. I. & O'Donnell, L., 2012, In : PLoS ONE. 7, 7, 19 p., e41718.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The emerging role of CXC chemokines in epithelial ovarian cancer

Rainczuk, A., Rao, J., Gathercole, J. L. & Stephens, A. N., Sep 2012, In : Reproduction. 144, 3, p. 303-317 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2011

A proteomic protocol to identify physiological substrates of pro-protein convertases

Nie, G. & Stephens, A. N., 2011, Proprotein Convertases. Humana Press, Vol. 768. p. 325-341 17 p. (Methods in Molecular Biology; vol. 768).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Combination of hydrogel nanoparticles and proteomics to reveal secreted proteins associated with decidualization of human uterine stromal cells

Paule, S., Meehan, K., Rainczuk, A., Stephens, A. N. & Nie, G-Y., 1 Sep 2011, In : Proteome Science. 9, 6 p., 50.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Proprotein convertase 5/6 is critical for embryo implantation in women: Regulating receptivity by cleaving EBP50, modulating ezrin binding, and membrane-cytoskeletal interactions

Heng, S., Cervero, A., Simon, C., Stephens, A. N., Li, Y., Zhang, J., Paule, S., Rainczuk, A., Singh, H., Quinonero, A., Tapia, A., Velasquez, L., Salamonsen, L., Rombauts, L. & Nie, G., 2011, In : Endocrinology. 152, 12, p. 5041 - 5052 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

2D-DiGE analysis of the human endometrial secretome reveals differences between receptive and nonreceptive states in fertile and infertile women

Hannan, N., Stephens, A., Rainczuk, A., Hincks, C., Rombauts, L. & Salamonsen, L., 2010, In : Journal of Proteome Research. 9, 12, p. 6256 - 6264 9 p.

Research output: Contribution to journalArticleResearchpeer-review

An optimized procedure for the capture, fractionation and proteomic analysis of proteins using hydrogel nanoparticles

Rainczuk, A., Meehan, K., Steer, D. L., Stanton, P. G., Robertson, D. M. & Stephens, A. N., 2010, In : Proteomics. 10, p. 332 - 336 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Post-translational modifications and protein-specific isoforms in endometriosis revealed by 2D DIGE

Stephens, A., Hannan, N., Rainczuk, A., Meehan, K., Chen, J., Nicholls, P., Rombauts, L., Stanton, P., Robertson, D. & Salamonsen, L., 2010, In : Journal of Proteome Research. 9, 5, p. 2438 - 2449 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomic analysis of the intestinal adaptation response reveals altered expression of fatty acid binding proteins following massive small bowel resection

Stephens, A. N., Pereira-Fantini, P. M., Wilson, G., Taylor, R. G., Rainczuk, A., Meehan, K. L., Sourial, M., Fuller, P. J., Stanton, P. G., Robertson, D. M. & Bines, J. E., 5 Mar 2010, In : Journal of Proteome Research. 9, 3, p. 1437-1449 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomic approach identifies alterations in cytoskeletal remodelling proteins during decidualization of human endometrial stromal cells

Paule, S. G., Airey, L. M., Li, Y., Stephens, A. N. & Nie, G., 5 Nov 2010, In : Journal of Proteome Research. 9, 11, p. 5739-5747 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomics and the search for biomarkers of female reproductive diseases

Meehan, K. L., Rainczuk, A., Salamonsen, L. A. & Stephens, A. N., Oct 2010, In : Reproduction. 140, 4, p. 505-519 15 p.

Research output: Contribution to journalArticleOtherpeer-review

2009

Depletion of high-abundance serum proteins from human uterine lavages enhances detection of lower-abundance proteins

Hannan, N. J., Stoikos, C. J., Stephens, A. & Salamonsen, L. A., 2009, In : Journal of Proteome Research. 8, 2, p. 1099 - 1103 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomic characterization of midproliferative and midsecretory human endometrium

Chen, J. I. C., Hannan, N. J., Mak, Y., Nicholls, P. K., Zhang, J., Rainczuk, A., Stanton, P. G., Robertson, D. M., Salamonsen, L. A. & Stephens, A. N., 3 Apr 2009, In : Journal of Proteome Research. 8, 4, p. 2032-2044 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomic identification of caldesmon as a physiological substrate of proprotein convertase 6 in human uterine decidual cells essential for pregnancy establishment

Kilpatrick, L. M., Stephens, A. N., Hardman, B. M., Salamonsen, L. A., Li, Y., Stanton, P. G. & Nie, G., 6 Nov 2009, In : Journal of Proteome Research. 8, 11, p. 4983-4992 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

A streamlined approach to high-throughput proteomics

Stephens, A. N., Quach, P. & Harry, E. J., Apr 2005, In : Expert Review of Proteomics. 2, 2, p. 173-185 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2003

Each yeast mitochondrial F1F0-ATP synthase complex contains a single copy of subunit 8

Stephens, A. N., Nagley, P. & Devenish, R. J., 2003, In : Biochimica et Biophysica Acta - Bioenergetics. 1607, 2-3, p. 181 - 189 9 p.

Research output: Contribution to journalArticleResearchpeer-review

The molecular neighbourhood of subunit 8 of yeast mitochondrial F1F0-ATP synthase probed by cysteine scanning mutagenesis and chemical modification

Stephens, A. N., Khan, M. A., Roucou, X., Nagley, P. & Devenish, R. J., 2003, In : Journal of Biological Chemistry. 278, 20, p. 17867 - 17875 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2000

Topology and proximity relationships of yeast mitochondrial ATP synthase subunit 8 determined by unique introduced cysteine residues

Stephens, A., Roucou, X., Artika, I. M., Devenish, R. J. & Nagley, P., 2000, In : European Journal of Biochemistry. p. 6443 - 6451 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1999

Topology of subunit 8 of yeast mitochondrial F

Nagley, P., Stephens, A., Devenish, R. J. & Roucou, X., 1999, p. POS-TUE-88 - POS-TUE-88. 1 p.

Research output: Contribution to conferenceAbstractOther

Topology of subunit 8 of yeast mitochondrial F

Stephens, A., Roucou, X., Devenish, R. J. & Nagley, P., 1999, p. A-30 - A-30. 1 p.

Research output: Contribution to conferenceAbstractOther