If you made any changes in Pure these will be visible here soon.

Research Output 2001 2019

2019
1 Citation (Scopus)

Potential Diagnostic Imaging of Alzheimer's Disease with Copper-64 Complexes That Bind to Amyloid-β Plaques

McInnes, L. E., Noor, A., Kysenius, K., Cullinane, C., Roselt, P., McLean, C. A., Chiu, F. C. K., Powell, A. K., Crouch, P. J., White, J. M. & Donnelly, P. S., 4 Mar 2019, In : Inorganic Chemistry. 58, 5, p. 3382-3395 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2017
13 Citations (Scopus)

Evaluation of robenidine analog NCL195 as a novel broad-spectrum antibacterial agent

Ogunniyi, A. D., Khazandi, M., Stevens, A. J., Sims, S. K., Page, S. W., Garg, S., Venter, H., Powell, A., White, K., Petrovski, K. R., Laven-Law, G., Tótoli, E. G., Salgado, H. R., Pi, H., Coombs, G. W., Shinabarger, D. L., Turnidge, J. D., Paton, J. C., McCluskey, A. & Trott, D. J., 1 Sep 2017, In : PLoS ONE. 12, 9, 23 p., e0183457.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2016
13 Citations (Scopus)

Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922)

Zheng, Z., Pinson, J. A., Mountford, S. J., Orive, S., Schoenwaelder, S. M., Shackleford, D., Powell, A., Nelson, E. M., Hamilton, J. R., Jackson, S., Jennings, I. G. & Thompson, P. E., 21 Oct 2016, In : European Journal of Medicinal Chemistry. 122, p. 339-351 13 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions

Drinkwater, N., Vinh, N. B., Mistry, S. N., Bamert, R. S., Ruggeri, C., Holleran, J. P., Loganathan, S., Paiardini, A., Charman, S. A., Powell, A. K., Avery, V. M., McGowan, S. & Scammells, P. J., 3 Mar 2016, In : European Journal of Medicinal Chemistry. 110, p. 43-64 22 p.

Research output: Contribution to journalArticleResearchpeer-review

2014
8 Citations (Scopus)

Simplified silvestrol analogues with potent cytotoxic activity

Hawkins, B. C., Lindqvist, L. M., Nhu, D. Q., Sharp, P. P., Segal, D., Powell, A. K., Campbell, M., Ryan, E., Chambers, J. M., White, J., Rizzacasa, M. A., Lessene, G., Huang, D. CS. & Burns, C. J., 2014, In : ChemMedChem. 9, 7, p. 1556 - 1566 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2013
11 Citations (Scopus)

3',4'-Bis-difluoromethoxycinnamoylanthranilate (FT061): An orally-active antifibrotic agent that reduces albuminuria in a rat model of progressive diabetic nephropathy

Williams, S. J., Zammit, S. C., Cox, A. J., Shackleford, D., Morizzi, J., Zhang, Y., Powell, A. K., Gilbert, R. E., Krum, H. & Kelly, D. J., 2013, In : Bioorganic and Medicinal Chemistry Letters. 23, 24, p. 6868 - 6873 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2012
22 Citations (Scopus)

FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomypathy

Zhang, Y., Edgley, A. J., Cox, A. J., Powell, A. K., Wang, B. H., Kompa, A. R., Stapleton, D. I., Zammit, S. C., Williams, S. J., Krum, H., Gilbert, R. E. & Kelly, D. J., 2012, In : European Journal of Heart Failure. 14, 5, p. 549 - 562 14 p.

Research output: Contribution to journalArticleResearchpeer-review

82 Citations (Scopus)

The hypoxia imaging agent Cu ii(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease

Hung, L., Villemagne, V., Cheng, L., Sherratt, N., Ayton, S., White, A., Crouch, P., Lim, S. C., Leong, S. L., Wilkins, S., George, J., Roberts, B., Pham, C., Liu, X., Chiu, F., Shackleford, D., Powell, A., Masters, C., Bush, A. I., O'Keefe, G. & 7 others, Culvenor, J., Cappai, R., Cherny, R., Donnelly, P., Hill, A., Finkelstein, D. & Barnham, K., 2012, In : Journal of Experimental Medicine. 209, 4, p. 837 - 854 18 p.

Research output: Contribution to journalArticleResearchpeer-review

2011
69 Citations (Scopus)

Diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII (atsm)) protects against peroxynitrite-induced nitrosative damage and prolongs survival in amyotrophic lateral sclerosis mouse model

Soon, C., Donnelly, P., Turner, B., Hung, L., Crouch, P., Sherratt, N., Tan, J-L., Lim, N., Lam, L., Bica, L., Lim, S. C., Hickey, J., Morizzi, J., Powell, A., Finkelstein, D., Culvenor, J., Masters, C., Duce, J., White, A., Barnham, K. & 1 others, Lin, Q-X., 2011, In : Journal of Biological Chemistry. 286, 51, p. 44035 - 44044 10 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

The microtubule depolymerising agent CYT997 causes extensive ablation of tumor vasculature in vivo

Burns, C., Fantino, E., Powell, A., Shnyder, S., Cooper, P., Nelson, S., Christophi, C., Malcontenti-Wilson, C., Dubljevic, V., Harte, M., Joffe, M., Phillips, I., Segal, D., Wilks, A. & Smith, G., 2011, In : Journal of Pharmacology and Experimental Therapeutics. 339, 3, p. 799 - 806 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2003
23 Citations (Scopus)

Motility in the isolated mouse colon: migrating motor complexes, myoelectric complexes and pressure waves

Powell, A. K., Fida, R. & Bywater, R. A. R., 2003, In : Neurogastroenterology and Motility. 15, 3, p. 257 - 266 10 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Murine intestinal migrating motor complexes: longitudinal components

Powell, A. K. & Bywater, R. A. R., 2003, In : Neurogastroenterology and Motility. 15, 3, p. 245 - 256 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2002
20 Citations (Scopus)

Neural integrity is essential for the propagation of colonic migrating motor complexes in the mouse

Powell, A. K., O'Brien, S. D., Fida, R. & Bywater, R. A. R., 2002, In : Neurogastroenterology and Motility. 14, 5, p. 495 - 504 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2001
31 Citations (Scopus)

Endogenous nitric oxide release modulates the direction and frequency of colonic migrating motor complexes in the isolated mouse colon

Powell, A. K. & Bywater, R. A. R., 2001, In : Neurogastroenterology and Motility. 13, 3, p. 221 - 228 8 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Ongoing nicotinic and non-nicotinic inputs to inhibitory neurons in the mouse colon

Powell, A. K., Fida, R. & Bywater, R. A. R., 2001, In : Clinical and Experimental Pharmacology and Physiology. 28, 10, p. 792 - 798 7 p.

Research output: Contribution to journalArticleResearchpeer-review