Projects per year
Personal profile
Biography
Professor Andrew Perkins
Perkins Group - Blood Cancer Genomics
Andrew is a Professor in the Australian Centre for Blood Diseases, within the School of Translational Medicine. Dr Perkins trained at RPA Hospital in Sydney in clinical and laboratory haematology, undertook his PhD in genetics at Walter and Eliza Hall Institute, then post-doctoral studies at Harvard University before returning to Australia in 1997.
Professor Perkins is a clinician-scientist who seeks to understand transcriptional control networks which underpin normal blood stem cell production and blood cancers. We intend to harness this knowledge to cure inherited or acquired human blood diseases.
Supervision interests
Extensive experience in RHD supervision:
26 PhD students
25 BSc Hons students
5 Masters students
1 BSc (Med) student
4 Masters of Genome Analytics Internships
Clinical activities
Head of Genomic Medicine, Alfred Health, Melbourne
Professor of Haematology, The Alfred Hospital, Melbourne
Clinical Lead in Myeloproliferative Neoplasms
Monash teaching commitment
Teaching in HUP3022 - Haematological Malignancies
Teaching in HUP3990 - Third Year Research Projects
GNA5041: Masters of Genome Analytics, second year lecture series
GNA5930: Masters in Genome Analytics Internships in Genome Curation
Community service
Australia Leukaemia and Lymphoma Group Subcommittee for Myeloproliferative Neoplasms - 2014 - ongoing
Lorne Genome Organising Committee 2016-2024
NHMRC GRPs in Oncology and Biochemistry 2007-2018
NHMRC Investigator Grant Review Panel 2020-2021
Ideas GRP 2021
Genomic Health Futures Mission GRP 2021-23
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Head of Genomic Medicine Alfred Health, Alfred Hospital
1 Jul 2020 → …
Professor of Haematology, Alfred Hospital
3 Jul 2017 → …
University of Queensland
Research area keywords
- KLF1
- Erythropoiesis
- Myelodysplasia
- Leukaemia
- Transcription factors
- Genome Editing
- Genomics
- Cancer Cell Biology
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Phase 3, Randomized, Double-blind, Add-on Study Evaluating the Safety and Efficacy of Navtemadlin Plus Ruxolitinib vs Placebo Plus Ruxolitinib in JAK Inhibitor-Naïve Patients with Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
Perkins, A. (Primary Chief Investigator (PCI))
6/11/24 → 5/11/26
Project: Research
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Defining the circulating genome of high-risk plasma cell disorders to improve risk stratification and clinical management
Mithraprabhu, S. (Primary Chief Investigator (PCI)), Khong, T. (Chief Investigator (CI)), Reynolds, J. (Chief Investigator (CI)), Murray, D. (Chief Investigator (CI)), Shah, J. (Chief Investigator (CI)), Wellard, C. (Chief Investigator (CI)), Spencer, A. (Associate Investigator (AI)), Ross, J. (Associate Investigator (AI)), Perkins, A. (Associate Investigator (AI)), Marks, A. (Associate Investigator (AI)), Beer, H. (Associate Investigator (AI)) & Henderson, M. (Associate Investigator (AI))
1/04/24 → 31/12/26
Project: Research
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A Phase 1, Open-Label, Multicenter Study of INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms
Perkins, A. (Primary Chief Investigator (PCI))
12/09/23 → 12/09/26
Project: Research
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Phase 1/2 study with an open-label dose escalation phase followed by a randomized, double-blind phase of SLN124 in patients with Polycythemia Vera
Perkins, A. (Primary Chief Investigator (PCI)) & Kennedy, N. (Project Manager)
13/07/23 → 12/07/25
Project: Research
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A Phase 3 Study of the Hepcidin Mimetic Rusfertide (PTG300) in Patients with Polycythemia Vera
Perkins, A. (Primary Chief Investigator (PCI)) & Malherbe, M. (Project Manager)
18/10/22 → 31/10/25
Project: Research
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Revisiting γ-globin gene repression by TR4
Perkins, A. C., 26 Dec 2024, In: Blood. 144, 26, p. 2691-2692 2 p.Research output: Contribution to journal › Editorial › Other › peer-review
Open Access -
Variability of bone marrow biopsy reporting affects accuracy of diagnosis of myeloproliferative neoplasms: data from the ALLG MPN01 registry
Ng, W. Y., Erber, W. N., Grigg, A., Dunne, K., Perkins, A., Forsyth, C. & Ross, D. M., 2024, In: Pathology. 56, 1, p. 75-80 6 p.Research output: Contribution to journal › Article › Research › peer-review
4 Citations (Scopus) -
Variants leading to dysfibrinogenaemia in the fibrinogen α-chain at residue Arg19 are not solely associated with bleeding, but also with thrombotic events—RESPONSE
Ramanan, R., McFadyen, J. D., Perkins, A. C. & Tran, H. A., Jun 2024, In: British Journal of Haematology. 204, 6, p. 2504 1 p.Research output: Contribution to journal › Letter › Other › peer-review
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A Novel RUNX1 Genetic Variant Identified in a Young Male with Severe Osteoporosis
Block, T. J., Shore-Lorenti, C., Zebaze, R., Kerr, P. G., Kalff, A., Perkins, A. C., Ebeling, P. R. & Milat, F., Sept 2023, In: JBMR Plus. 7, 9, 8 p., e10791.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Congenital fibrinogen disorders—Strengthening genotype–phenotype correlations through novel genetic diagnostic tools
Ramanan, R., McFadyen, J. D., Perkins, A. C. & Tran, H. A., Nov 2023, In: British Journal of Haematology. 203, 3, p. 355-368 14 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access11 Citations (Scopus)
Prizes
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Albert G. Baikie Memorial Medal
Perkins, A. (Recipient), 1991
Prize: Prize (including medals and awards)
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Lucille P. Markey Postdoctoral Research Fellowship
Perkins, Andrew (Recipient), 1993
Prize: Competitive Fellowships
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Medical Postgraduate Research Fellowship
Perkins, Andrew (Recipient), 1989
Prize: Competitive Fellowships
Activities
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Investigator Grant Panel Committee Member
Andrew Perkins (Executive Member)
Mar 2019 → May 2019Activity: External Academic Engagement › Peer review panel or committee
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Novartis Pharmaceuticals Australia Pty Limited (External organisation)
Andrew Perkins (Member)
21 Feb 2019Activity: Industry, Government and Philanthropy Engagement and Partnerships › Consultancy
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Gordon Research Conference on Red Cells
Andrew Perkins (Invited speaker)
14 Jul 2019 → 19 Jul 2019Activity: Participating in or organising an event types › Contribution to conference
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Lorne Genome Conference 2019
Andrew Perkins (Organiser)
17 Feb 2019 → 19 Feb 2019Activity: Participating in or organising an event types › Contribution to conference
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Centre for Cancer Biology
Andrew Perkins (Visiting researcher)
12 Sept 2019Activity: Visiting an external institution types › Visiting an external academic institution