Projects per year
Personal profile
Biography
Dr. Andrew Laslett is a Research Team Leader with the CSIRO Manufacturing business unit, where he leads a human pluripotent stem cell biology research team; He also holds an Adjunct Associate Professor position with the Australian Regenerative Medicine Institute at Monash University and is an Honorary Senior Fellow with the School of BioSciences at Melbourne University. Since 2001, Andrew and his laboratory have focused on elucidating the complex biology of human embryonic stem cells (hESC), examined methods for the differentiation of hESC to renal progenitor cells and more recently begun comparing hESC to reprogrammed human cells termed induced pluripotent stem (iPS) cells. His laboratory is currently focused on exploiting the basic biology of these cell types to create novel cell lines and tools that enhance human pluripotent cell research translation within CSIRO, Australia and internationally.Current projects include:
(i) functional uses of monoclonal antibodies to cell surface proteins on human pluripotent stem cells
(ii) the production of a "disease in a dish" model of human breast cancer
(iii) optimisation of human hepatocyte production conditions for use in bio-artificial liver devices
Prior to his current role with CSIRO, Andrew was a Senior Scientist and Group Leader of the Human Embryonic Stem Cell Technology Laboratory at the Australian Stem Cell Centre (ASCC) following Senior Research Fellow appointments in the Laboratory of Embryonic Stem Cell Biology and the Centre for Reproduction and Development, Monash Institute of Medical Research, Monash University. He obtained his BSc (Hons) and PhD (1996) from Monash University prior to undertaking postdoctoral positions in both Hong Kong and Philadelphia, USA.
External positions
Research Team Leader, CSIRO Manufacturing and Infrastructure Technology (Victoria)
1 Aug 2009 → …Research area keywords
- embryonic stem cells
- induced pluripotent stem cells
- stem cells
- antibodies
- breast cancer
- hepatocyte
Network
Projects
- 1 Finished
-
Multiple Sclerosis Therapy: Human Pluripotent Stem Cell-derived Neural Progenitor Cells.
Bernard, C., Laslett, A. & O'Brien, C.
National Health and Medical Research Council (NHMRC) (Australia)
1/07/12 → 30/12/16
Project: Research
Research output
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Hepatic differentiation of stem cells in 2d and 3d biomaterial systems
Zhao, X., Zhu, Y., Laslett, A. L. & Chan, H. F., Jun 2020, In : Bioengineering. 7, 2, 14 p., 47.Research output: Contribution to journal › Review Article › Research › peer-review
Open AccessFile1 Citation (Scopus) -
Reprogramming roadmap reveals route to human induced trophoblast stem cells
Liu, X., Ouyang, J. F., Rossello, F. J., Tan, J. P., Davidson, K. C., Valdes, D. S., Schröder, J., Sun, Y. B. Y., Chen, J., Knaupp, A. S., Sun, G., Chy, H. S., Huang, Z., Pflueger, J., Firas, J., Tano, V., Buckberry, S., Paynter, J. M., Larcombe, M. R., Poppe, D. & 19 others, , 1 Oct 2020, In : Nature. 586, p. 101-107 7 p.Research output: Contribution to journal › Article › Research › peer-review
7 Citations (Scopus) -
The application of cell surface markers to demarcate distinct human pluripotent states
Goodwin, J., Laslett, A. L. & Rugg-Gunn, P. J., 1 Feb 2020, In : Experimental Cell Research. 387, 1, 9 p., 111749.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile2 Citations (Scopus) -
Three-dimensional differentiation of human pluripotent stem cell-derived neural precursor cells using tailored porous polymer scaffolds
Murphy, A. R., Haynes, J. M., Laslett, A. L., Cameron, N. R. & O'Brien, C. M., 1 Jan 2020, In : Acta Biomaterialia. 101, p. 102-116 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open AccessFile9 Citations (Scopus) -
Optimized peptide functionalization of thiol-acrylate emulsion-templated porous polymers leads to expansion of human pluripotent stem cells in 3D culture
Ratcliffe, J. L., Walker, M., Eissa, A. M., Du, S., Przyborski, S. A., Laslett, A. L. & Cameron, N. R., 15 Sep 2019, In : Journal of Polymer Science, Part A: Polymer Chemistry. 57, 18, p. 1974-1981 8 p.Research output: Contribution to journal › Article › Research › peer-review
8 Citations (Scopus)