Projects per year
Personal profile
Biography
Dr. Andrew Laslett is a Research Team Leader with the CSIRO Manufacturing business unit, where he leads a human pluripotent stem cell biology research team; He also holds an Adjunct Associate Professor position with the Australian Regenerative Medicine Institute at Monash University and is an Honorary Senior Fellow with the School of BioSciences at Melbourne University. Since 2001, Andrew and his laboratory have focused on elucidating the complex biology of human embryonic stem cells (hESC), examined methods for the differentiation of hESC to renal progenitor cells and more recently begun comparing hESC to reprogrammed human cells termed induced pluripotent stem (iPS) cells. His laboratory is currently focused on exploiting the basic biology of these cell types to create novel cell lines and tools that enhance human pluripotent cell research translation within CSIRO, Australia and internationally.Current projects include:
(i) functional uses of monoclonal antibodies to cell surface proteins on human pluripotent stem cells
(ii) the production of a "disease in a dish" model of human breast cancer
(iii) optimisation of human hepatocyte production conditions for use in bio-artificial liver devices
Prior to his current role with CSIRO, Andrew was a Senior Scientist and Group Leader of the Human Embryonic Stem Cell Technology Laboratory at the Australian Stem Cell Centre (ASCC) following Senior Research Fellow appointments in the Laboratory of Embryonic Stem Cell Biology and the Centre for Reproduction and Development, Monash Institute of Medical Research, Monash University. He obtained his BSc (Hons) and PhD (1996) from Monash University prior to undertaking postdoctoral positions in both Hong Kong and Philadelphia, USA.
External positions
Research Team Leader, CSIRO Manufacturing and Infrastructure Technology
1 Aug 2009 → …Research area keywords
- embryonic stem cells
- induced pluripotent stem cells
- stem cells
- antibodies
- breast cancer
- hepatocyte
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
- 4 Finished
Unveiling the human reprogramming pathway
National Health & Medical Research Council (NHMRC)
1/01/16 → 31/12/19
Project: Research
Inducing and controlling cellular plasticity
Polo, J., Laslett, A. & Ramialison, M.
National Health & Medical Research Council (NHMRC)
1/01/15 → 31/12/17
Project: Research
Multiple Sclerosis Therapy: Human Pluripotent Stem Cell-derived Neural Progenitor Cells.
Bernard, C., Laslett, A. & O'Brien, C.
National Health & Medical Research Council (NHMRC)
1/07/12 → 30/12/16
Project: Research
Stem Cells Australia
Little, M., Kilpatrick, T., Gardner, D., Hilton, D., Polo, J., Hobbs, R., Bourne, J., Marcelle, C., Rosenthal, N., Stanley, E., Elefanty, A., Barberi, T., Gray, P., Cooper-White, J., Wainwight, B., Wolvetang, E. J., Nielsen, L., Bartlett, P. F., Wells, C., Harvey, R. P., Graham, R., Palpant, N., Alexander, W. S., Laslett, A., Nilsson, S., Haylock, D., Grimmond, S. M., McDonald, V., Abud, H., Currie, P., Haynes, J., Janovjak, H., Martino, M. & Merson, T.
Australian Research Council (ARC), Monash University – Internal University Contribution
1/01/11 → 31/12/19
Project: Research
Research Output
Optimized peptide functionalization of thiol-acrylate emulsion-templated porous polymers leads to expansion of human pluripotent stem cells in 3D culture
Ratcliffe, J. L., Walker, M., Eissa, A. M., Du, S., Przyborski, S. A., Laslett, A. L. & Cameron, N. R., 15 Sep 2019, In : Journal of Polymer Science, Part A: Polymer Chemistry. 57, 18, p. 1974-1981 8 p.Research output: Contribution to journal › Article › Research › peer-review
5
Citations
(Scopus)
Cell surface markers for the identification and study of human naive pluripotent stem cells
Trusler, O., Huang, Z., Goodwin, J. & Laslett, A. L., 1 Jan 2018, In : Stem Cell Research. 26, p. 36-43 8 p.Research output: Contribution to journal › Review Article › Other › peer-review
Open Access
File
10
Citations
(Scopus)
Designer macrophages: Pitfalls and opportunities for modelling macrophage phenotypes from pluripotent stem cells
Rajab, N., Rutar, M., Laslett, A. L. & Wells, C. A., 1 Nov 2018, In : Differentiation. 104, p. 42-49 8 p.Research output: Contribution to journal › Review Article › Research › peer-review
Long-Term Maintenance of Human Pluripotent Stem Cells on cRGDfK-Presenting Synthetic Surfaces
Lambshead, J. W., Meagher, L., Goodwin, J., Labonne, T., Ng, E., Elefanty, A., Stanley, E., O'Brien, C. M. & Laslett, A. L., 1 Dec 2018, In : Scientific Reports. 8, 1, 16 p., 701.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
3
Citations
(Scopus)
Physiological oxygen culture reveals retention of metabolic memory in human induced pluripotent stem cells
Harvey, A. J., O'Brien, C., Lambshead, J., Sheedy, J. R., Rathjen, J., Laslett, A. L. & Gardner, D. K., 1 Mar 2018, In : PLoS ONE. 13, 3, 19 p., e0193949.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
6
Citations
(Scopus)