1996 …2022
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Research Output 1996 2019

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2019

Dexamethasone improves therapeutic outcomes in a preclinical bacterial epididymitis mouse model

Klein, B., Pant, S., Bhushan, S., Kautz, J., Rudat, C., Kispert, A., Pilatz, A., Wijayarathna, R., Middendorff, R., Loveland, K., Hedger, M. & Meinhardt, A., 8 Jul 2019, In : Human Reproduction. 34, 7, p. 1195-1205 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Investigation of activin A in inflammatory responses of the testis and its role in the development of testicular fibrosis

Kauerhof, A. C., Nicolas, N., Bhushan, S., Wahle, E., Loveland, K. A., Fietz, D., Bergmann, M., Groome, N. P., Kliesch, S., Schuppe, H-C., Pilatz, A., Meinhardt, A., Hedger, M. P. & Fijak, M., 24 Jul 2019, (Accepted/In press) In : Human Reproduction. 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Comparative analysis of activins A and B in the adult mouse epididymis and vas deferens

Wijayarathna, R., de Kretser, D. M., Sreenivasan, R., Ludlow, H., Middendorff, R., Meinhardt, A., Loveland, K. L. & Hedger, M. P., 1 Jan 2018, In : Reproduction. 155, 1, p. 15-23 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Infectious, inflammatory and 'autoimmune' male factor infertility: How do rodent models inform clinical practice?

Fijak, M., Pilatz, A., Hedger, M. P., Nicolas, N., Bhushan, S., Michel, V., Tung, K. S. K., Schuppe, H. C. & Meinhardt, A., 1 Jul 2018, In : Human Reproduction Update. 24, 4, p. 416-441 26 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Activin and follistatin interactions in the male reproductive tract: Activin expression and morphological abnormalities in mice lacking follistatin 288

Wijayarathna, R., Sarraj, M. A., Genovese, R., Girling, J. E., Michel, V., Ludlow, H., Loveland, K. L., Meinhardt, A., de Kretser, D. M. & Hedger, M. P., May 2017, In : Andrology. 5, 3, p. 578-588 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Activin over-expression in the testis of mice lacking the inhibin α-subunit gene is associated with androgen deficiency and regression of the male reproductive tract

Wijayarathna, R., de Kretser, D. M., Meinhardt, A., Middendorff, R., Ludlow, H., Groome, N. P., Loveland, K. A. & Hedger, M. P., 15 Jul 2017, In : Molecular and Cellular Endocrinology. 470, p. 188-198 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of the micro-environment of the testis that shapes the phenotype and function of testicular macrophages

Wang, Z-M., Fijak, M., Hossain, H., Markmann, M., Nusing, R. M., Lochnit, G., Hartmann, M. F., Wudy, S. A., Zhang, L., Gu, H., Konrad, L., Chakraborty, T., Meinhardt, A. & Bhushan, S., 1 Jun 2017, In : Journal of Immunology. 198, 11, p. 4327-4340 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Induction of EAO in mice: responses to 2 elevated circulating levels of the activin-binding protein, follistatin

Nicholas, N., Muir, J. A., Hayward, S., Chen, J. L., Stanton, P. G., Gregorevic, P., de Kretser, D. M., Loveland, K. L., Bhushan, S., Meinhardt, A., Fijak, M. & Hedger, M. P., 1 Sep 2017, In : Reproduction. 154, 3, p. 293-305 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo-orchitis in mice

Nicolas, N., Michel, V., Bhushan, S., Wahle, E., Hayward, S., Ludlow, H., De Kretser, D. M., Loveland, K., Schuppe, H. C., Meinhardt, A., Hedger, M. P. & Fijak, M., 13 Feb 2017, In : Scientific Reports. 7, 42391.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2016

Desialylation of spermatozoa and epithelial cell glycocalyx is a consequence of bacterial infection of the epididymis

Khosravi, F., Michel, V., Galuska, C. E., Bhushan, S., Christian, P., Schuppe, H. C., Pilatz, A., Galuska, S. P. & Meinhardt, A., 19 Aug 2016, In : Journal of Biological Chemistry. 291, 34, p. 17717-17726 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Uropathogenic Escherichia coli causes fibrotic remodelling of the epididymis

Michel, V., Duan, Y., Stoschek, E., Bhushan, S., Middendorff, R., Young, J. M., Loveland, K. L., Kretser, D. M. D., Hedger, M. P. & Meinhardt, A., 1 Sep 2016, In : Journal of Pathology. 240, 1, p. 15-24 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Uropathogenic Escherichia coli epigenetically manipulate host cell death pathways

Zhang, Z., Wang, Z-M., Eisel, F., Tchatalbachev, S., Chakraborty, T., Meinhardt, A. & Bhushan, S., 1 Apr 2016, In : Journal of Infectious Diseases. 213, 7, p. 1198-1207 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2015

Epididymitis: revelations at the convergence of clinical and basic sciences

Michel, V., Pilatz, A., Hedger, M. P. & Meinhardt, A., 2015, In : Asian Journal of Andrology. 17, 5, p. 756 - 763 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
2014

The role of macrophage migration inhibitory factor in autoimmune liver disease

Assis, D. N., Leng, L., Du, X., Zhang, C. K., Grieb, G., Merk, M., Baeza Garcia, A., McCrann, C. H., Chapiro, J., Meinhardt, A., Mizue, Y., Nikolic-Paterson, D. J., Bernhagen, J., Kaplan, M. M., Zhao, H., Boyer, J. L. & Bucala, R., 2014, In : Hepatology. 59, 2, p. 580 - 591 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Uropathogenic Escherichia coli modulates innate immunity to suppress Th1-mediated inflammatory responses during infectious epididymitis

Lang, T., Hudemann, C., Tchatalbachev, S., Stammler, A., Michel, V., Aslani, F., Bhushan, S., Chakraborty, T., Renz, H. & Meinhardt, A., Mar 2014, In : Infection and Immunity. 82, 3, p. 1104-1111 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2013

Prostatitis and andrological implications

Wagenlehner, F. M. E., Pilatz, A., Linn, T., Diemer, T., Schuppe, H. C., Schagdarsurengin, U., Hossain, H., Meinhardt, A., Ellem, S. J., Risbridger, G. P. & Weidner, W., 2013, In : Minerva Urologica e Nefrologica. 65, 2, p. 117 - 123 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Structural and functional integrity of spermatozoa is compromised as a consequence of acute uropathogenic E. Coli-associated epididymitis

Lang, T., Dechant, M., Sanchez, V., Wistuba, J., Boiani, M., Pilatz, A., Stammler, A., Middendorff, R., Schuler, G., Bhushan, S., Tchatalbachev, S., Wübbeling, F., Burger, M., Chakraborty, T., Mallidis, C. & Meinhardt, A., 2013, In : Biology of Reproduction. 89, 3, 59.

Research output: Contribution to journalArticleResearchpeer-review

2011

Immunological, paracrine and endocrine aspects of testicular immune privilege

Meinhardt, A. & Hedger, M., 2011, In : Molecular and Cellular Endocrinology. 335, 1, p. 60 - 68 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

Cytokine profiles in the testes of rats treated with lipopolysaccharide reveal localized suppression of inflammatory responses

O'Bryan, M. K., Gerdprasert, O., Nikolic-Paterson, D. J., Meinhardt, A., Muir, J. A., Foulds, L. M., Phillips, D. J., de Kretser, D. M. & Hedger, M. P., 2005, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 288, 6, p. R1744 - R1755 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Regulatory cytokine expression and interstitial fluid formation in the normal and inflamed rat testis are under Leydig cell control

Hedger, M. P., Klug, J., Frohlich, S., Muller, R. & Meinhardt, A., 2005, In : Journal of Andrology. 26, 3, p. 379 - 386 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2003

Cytokines and the immune-testicular axis

Hedger, M. P. & Meinhardt, A., 2003, In : Journal of Reproductive Immunology. 58, 1, p. 1 - 26 26 p.

Research output: Contribution to journalArticleResearchpeer-review

Expression of a novel factor, short-type PB-cadherin, in Sertoli cells and spermatogenic stem cells of the neonatal rat testis

Wu, J., Jester, W. F., Laslett, A. L., Meinhardt, A. & Orth, J. M., 2003, In : Journal of Endocrinology. 176, 3, p. 381 - 391 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2001

Tpx-1 is a component of the outer dense fibers and acrosome of rat spermatozoa

O'Bryan, M. K., Sebire, K. L., Meinhardt, A., Edgar, K., Keah, H-H., Hearn, M. T. W. & de Kretser, D. M., 2001, In : Molecular Reproduction and Development. 58, p. 116 - 125 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2000

Activin maintains the condensed type of mitochondria in germ cells

Meinhardt, A., McFarlane, J. R., Seitz, J. & de Kretser, D. M., 2000, In : Molecular and Cellular Endocrinology. p. 111 - 117 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Local regulation of T cell numbers and lymphocyte-inhibiting activity in the interstitial tissue of the adult rat testis

Hedger, M. P. & Meinhardt, A., Oct 2000, In : Journal of Reproductive Immunology. 48, 2, p. 69-80 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Macrophage migration inhibitory factor (MIF) as a paracrine mediator in the interaction of testicular somatic cells

Meinhardt, A., Bacher, M., Wennemuth, G., Eickhoff, R. & Hedger, M., 2000, In : Andrologia. 32, 1, p. 46-48 3 p.

Research output: Contribution to journalArticleOtherpeer-review

The roles of inhibin and related peptides in gonadal function

de Kretser, D. M., Meinhardt, A., Meehan, T., Phillips, D. J., O'Bryan, M. K. & Loveland, K. L., 2000, In : Molecular and Cellular Endocrinology. p. 43 - 46 4 p.

Research output: Contribution to journalArticleResearchpeer-review

1999

A switch in the cellular localization of macrophage migration inhibitory factor in the rat testis after ethane dimethane sulfonate treatment

Meinhardt, A., Bacher, M., O'Bryan, M. K., McFarlane, J. R., Mallidis, C., Lehmann, C., Metz, C. N., de Kretser, D. M., Bucala, R. & Hedger, M., 1999, In : Journal of Cell Science. p. 1337 - 1344 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1998

Localization of follistatin in the rat testis

Meinhardt, A., O'Bryan, M. K., McFarlane, J. R., Loveland, K. L., Mallidis, C., Foulds, L. M., Phillips, D. J. & de Kretser, D. M., 1998, In : Journal of Reproduction and Fertility. p. 233 - 241 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Local regulation of macrophage subsets in the adult rat testis: examination of the roles of the seminiferous tubules, testosterone, and macrophage-migration inhibitory factor

Meinhardt, A., Bacher, M., Metz, C. N., Bucala, R., Wreford, N. G., Lan, H., Atkins, R. C. & Hedger, M., 1998, In : Biology of Reproduction. p. 371 - 378 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Reversal of established rat crescentic glomerulonephritis by blockade of macrophage migration inhibitory factor (MIF): Potential role of MIF in regulating glucocorticoid production

Yang, N., Nikolic-Paterson, D. J., Ng, Y. Y., Mu, W., Metz, C., Bacher, M., Meinhardt, A., Bucala, R., Atkins, R. C. & Lan, H. Y., 1 Sep 1998, In : Molecular Medicine. 4, 6, p. 413-424 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Spermatogenesis

De Kretser, D. M., Loveland, K. L., Meinhardt, A., Simorangkir, D. & Wreford, N., 1 Jan 1998, In : Human Reproduction. 13, SUPPL. 1, p. 1-8 8 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
1997

Paracrine regulation of cellular interactions in the testis : factors in search of a function

Schlatt, S., Meinhardt, A. & Nieschlag, A., 1997, In : European Journal of Endocrinology. p. 107 - 117 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Spermatogenesis

de Kretser, D. M., Loveland, K. L., Meinhardt, A., Simorangkir, D. R. & Wreford, N. G., 1997, In : Human Reproduction. p. 101 - 108 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The pathogenic role of macrophage migration inhibitory factor in immunologically induced kidney disease in the rat

Lan, H. Y., Bacher, M., Yang, N., Mu, W., Nikolic-Paterson, D. J., Metz, C., Meinhardt, A., Bucala, R. & Atkins, R. C., 21 Apr 1997, In : Journal of Experimental Medicine. 185, 8, p. 1455-1465 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1996

De novo renal expression of macrophage migration inhibitory factor during the development of rat crescentic glomerulonephritis

Lan, H. Y., Mu, W., Yang, N., Meinhardt, A., Nikolic-Paterson, D. J., Ng, Y. Y., Bacher, M., Atkins, R. C. & Bucala, R., 1 Jan 1996, In : American Journal of Pathology. 149, 4, p. 1119-1127 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Macrophage migration inhibitory factor production by Leydig cells: Evidence for a role in the regulation of testicular function

Meinhardt, A., Bacher, M., McFarlane, J. R., Metz, C. N., Seitz, J., Hedger, M. P., De Kretser, D. M. & Bucala, R., 1996, In : Endocrinology. 137, 11, p. 5090-5095 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Microtubule-associated protein-2 in the rat testis: A novel site of expression

Loveland, K. L., Hayes, T. M., Meinhardt, A., Zlatic, K. S., Parvinen, M., De Kretser, D. M. & McFarlane, J. R., 1 Apr 1996, In : Biology of Reproduction. 54, 4, p. 896-904 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access