1978 …2022
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Research Output 1978 2019

2006

Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival

Eremina, V., Cui, S., Gerber, H., Ferrara, N., Haigh, J., Nagy, A., Ema, M., Rossant, J., Jothy, S. & Miner, J. H., 2006, In : Journal of the American Society of Nephrology. 17, 3, p. 724-735 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival

Wada, T., Haigh, J. J., Ema, M., Hitoshi, S., Chaddah, R., Rossant, J., Nagy, A. & van der Kooy, D., 2006, In : Journal of Neuroscience. 26, 25, p. 6803-6812 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

Aberrant bone formation in mice over-expressing specific VEGF isoforms in cartilage.

Maes, C., Haigh, J., Chan, A., Haigh, K., Bouillon, R., Carmeliet, G. & Nagy, A., 2005, In : Journal of Bone and Mineral Research. 20, 9, p. 39 1 p.

Research output: Contribution to journalArticleResearch

"Agouti NOD": Identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells

Chen, J., Reifsnyder, P. C., Scheuplein, F., Schott, W. H., Mileikovsky, M., Soodeen-Karamath, S., Nagy, A., Dosch, M. H., Ellis, J., Koch-Nolte, F. & Leiter, E. H., Oct 2005, In : Mammalian Genome. 16, 10, p. 775-783 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction

Belteki, G., Haigh, J., Kabacs, N., Haigh, K., Sison, K., Costantini, F., Whitsett, J., Quaggin, S. E. & Nagy, A., 2005, In : Nucleic Acids Research. 33, 5, p. e51-e51

Research output: Contribution to journalArticleResearch

Donor hematopoietic cells from transgenic mice that express GFP are immunogenic in immunocompetent recipients

Bubnic, S. J., Nagy, A. & Keating, A., Aug 2005, In : Hematology. 10, 4, p. 289-295 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Ectopic expression of KitD814Y in spermatids of transgenic mice, interferes with sperm morphogenesis

Schnabel, D., Ramírez, L., Gertsenstein, M., Nagy, A. & Lomelí, H., May 2005, In : Developmental Dynamics. 233, 1, p. 29-40 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Phenotypic analyses of mouse embryos with ubiquitous expression of Oct4: Effects on mid-hindbrain patterning and gene expression

Ramos-Mejía, V., Escalante-Alcalde, D., Kunath, T., Ramírez, L., Gertsenstein, M., Nagy, A. & Lomelí, H., Jan 2005, In : Developmental Dynamics. 232, 1, p. 180-190 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development

Takeuchi, J. K., Mileikovskaia, M., Koshiba-Takeuchi, K., Heidt, A. B., Mori, A. D., Arruda, E. P., Gertsenstein, M., Georges, R., Davidson, L., Mo, R., Hui, C. C., Henkelman, R. M., Nemer, M., Black, B. L., Nagy, A. & Bruneau, B. G., May 2005, In : Development. 132, 10, p. 2463-2474 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells

Haigh, J. J., Ema, M., Haigh, K., Gertsenstein, M., Greer, P., Rossant, J., Nagy, A. & Wagner, E. F., 2004, In : Blood. 103, 3, p. 912-920 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A specific requirement for PDGF-C in palate formation and PDGFR-α signaling

Ding, H., Wu, X., Boström, H., Kim, I., Wong, N., Tsoi, B., O'Rourke, M., Koh, G. Y., Soriano, P., Betsholtz, C., Hart, T. C., Marazita, M. L., Field, L. L., Tam, P. P. L. & Nagy, A., Oct 2004, In : Nature Genetics. 36, 10, p. 1111-1116 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Cre recombinase specificity defined by the tau locus

Korets-Smith, E., Lindemann, L., Tucker, K. L., Jiang, C., Kabacs, N., Belteki, G., Haigh, J., Gertsenstein, M. & Nagy, A., 2004, In : Genesis. 40, 3, p. 131-138 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Essential role of brain-derived neurotrophic factor in adult hippocampal function

Monteggia, L. M., Barrot, M., Powell, C. M., Berton, O., Galanis, V., Gemelli, T., Meuth, S., Nagy, A., Greene, R. W. & Nestler, E. J., 20 Jul 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 29, p. 10827-10832 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Genetic manipulation of mice to study cardiovascular disease

Quaggin, S. E., Chan, A. & Nagy, A., 17 Dec 2004, In : Drug Discovery Today: Disease Models. 1, 3, p. 243-248 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY-Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells

Haigh, JJ., Ema, M., Haigh, K., Gertsenstein, M., Greer, P., Rossant, J., Nagy, A. & Wagner, EF., 2004, In : Blood. 103, 3, p. 912-920 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Hypoxia and hypoxia-inducible factor-1 target genes in central nervous system radiation injury: A role for vascular endothelial growth factor

Nordal, R. A., Nagy, A., Pintilie, M. & Wong, C. S., 15 May 2004, In : Clinical Cancer Research. 10, 10, p. 3342-3353 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Mouse in red: Red fluorescent protein expression in mouse ES cells, embryos, and adult animals

Vintersten, K., Monetti, C., Gertsenstein, M., Zhang, P., Laszlo, L., Biechele, S. & Nagy, A., Dec 2004, In : Genesis. 40, 4, p. 241-246 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Oct4 is required for primordial germ cell survival

Kehler, J., Tolkunova, E., Koschorz, B., Pesce, M., Gentile, L., Boiani, M., Lomelí, H., Nagy, A., McLaughlin, K. J., Schöler, H. R. & Tomilin, A., Nov 2004, In : EMBO Reports. 5, 11, p. 1078-1083 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Regulation of murine telomere length by Rtel: An essential gene encoding a helicase-like protein

Ding, H., Schertzer, M., Wu, X., Gertsenstein, M., Selig, S., Kammori, M., Pourvali, R., Poon, S., Vulto, I., Chavez, E., Tam, P. P. L., Nagy, A. & Lansdorp, P. M., 25 Jun 2004, In : Cell. 117, 7, p. 873-886 14 p.

Research output: Contribution to journalArticleResearchpeer-review

SCL interacts with VEGF to suppress apoptosis at the onset of hematopoiesis

Martin, R., Lahlil, R., Damert, A., Miquerol, L., Nagy, A., Keller, G. & Hoang, T., Feb 2004, In : Development. 131, 3, p. 693-702 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The gut microbiota as an environmental factor that regulates fat storage

Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Gou, Y. K., Nagy, A., Semenkovich, C. F. & Gordon, J. I., 2 Nov 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 44, p. 15718-15723 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The Knockout Mouse Project

Austin, C. P., Battey, J. F., Bradley, A., Bucan, M., Capecchi, M., Collins, F. S., Dove, W. F., Duyk, G., Dymecki, S., Eppig, J. T., Grieder, F. B., Heintz, N., Hicks, G., Insel, T. R., Joyner, A., Koller, B. H., Lloyd, K. C. K., Magnuson, T., Moore, M. W., Nagy, A. & 21 othersPollock, J. D., Roses, A. D., Sands, A. T., Seed, B., Skarnes, W. C., Snoddy, J., Soriano, P., Stewart, D. J., Stewart, F., Stillman, B., Varmus, H., Varticovski, L., Verma, I. M., Vogt, T. F., Von Melchner, H., Witkowski, J., Woychik, R. P., Wurst, W., Yancopoulos, G. D., Young, S. G. & Zambrowicz, B., Sep 2004, In : Nature Genetics. 36, 9, p. 921-924 4 p.

Research output: Contribution to journalComment / DebateResearchpeer-review

Vascular endothelial growth factor controls neuronal migration and cooperates with SemaSA to pattern distinct compartments of the facial nerve

Schwarz, Q., Gu, C., Fujisawa, H., Sabelko, K., Gertsenstein, M., Nagy, A., Taniguchi, M., Kolodkin, A. L., Ginty, D. D., Shima, D. T. & Ruhrberg, C., 15 Nov 2004, In : Genes and Development. 18, 22, p. 2822-2834 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Whole mount analysis of the embryonic vasculature

Haigh, J. J. & Nagy, A., 2004, Methods in Endothelial Cell Biology. Springer, p. 325-336 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Report)Research

2003

Aggregation of embryos and embryonic stem cells.

Maatman, R., Gertsenstein, M., de Meijer, E., Nagy, A. & Vintersten, K., 2003, In : Methods in molecular biology (Clifton, N.J.). 209, p. 201-230 30 p.

Research output: Contribution to journalArticleResearchpeer-review

Comment on "Failure of bone marrow cells to transdifferentiate into neural cells in vivo".

Mezey, E., Nagy, A., Szalayova, I., Key, S., Bratincsak, A., Baffi, J. & Shahar, T., 21 Feb 2003, In : Science. 299, 5610

Research output: Contribution to journalComment / DebateResearchpeer-review

Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production

Kimura, T., Suzuki, A., Fujita, Y., Yomogida, K., Lomeli, H., Asada, N., Ikeuchi, M., Nagy, A., Mak, T. W. & Nakano, T., Apr 2003, In : Development. 130, 8, p. 1691-1700 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Contrasting effects of VEGF gene disruption in embryonic stem cell-derived versus oncogene-induced tumors

Viloria-Petit, A., Miquerol, L., Yu, J. L., Gertsenstein, M., Sheehan, C., May, L., Henkin, J., Lobe, C., Nagy, A., Kerbel, R. S. & Rak, J., 15 Aug 2003, In : EMBO Journal. 22, 16, p. 4091-4102 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

Haigh, J. J., Morelli, P. I., Gerhardt, H., Haigh, K., Tsien, J., Damert, A., Miquerol, L., Muhlner, U., Klein, R., Ferrara, N. & Nagy, A., 2003, In : Developmental Biology. 262, 2, p. 225-241 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking

Metzler, M., Li, B., Gan, L., Georgiou, J., Gutekunst, C. A., Wang, Y., Torre, E., Devon, R. S., Oh, R., Legendre-Guillemin, V., Rich, M., Alvarez, C., Gertsenstein, M., McPhersons, P. S., Nagy, A., Wang, Y. T., Roder, J. C., Raymond, L. A. & Hayden, M. R., 1 Jul 2003, In : EMBO Journal. 22, 13, p. 3254-3266 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Expanded parietal cell pool in transgenic mice unable to synthesize histamine

Hunyady, B., Zólyomi, A., Czimmer, J., Mózsik, G., Kozicz, T., Buzás, E., Tanaka, S., Ichikawa, A., Nagy, A., Palkovits, M. & Falus, A., 1 Feb 2003, In : Scandinavian Journal of Gastroenterology. 38, 2, p. 133-140 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

Eremina, V., Sood, M., Haigh, J., Nagy, A., Lajoie, G., Ferrara, N., Gerber, H-P., Kikkawa, Y., Miner, J. H. & Quaggin, S. E., 2003, In : Journal of Clinical Investigation. 111, 5, p. 707-716 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Hyperleptinemia, visceral adiposity, and decreased glucose tolerance in mice with a targeted disruption of the histidine decarboxylase gene

Fülöp, A. K., Földes, A., Buzás, E., Hegyi, K., Miklós, I. H., Romics, L., Kleiber, M., Nagy, A., Falus, A. & Kovács, K. J., 1 Oct 2003, In : Endocrinology. 144, 10, p. 4306-4314 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Impaired intervertebral disc formation in the absence of Jun

Behrens, A., Haigh, J., Mechta-Grigoriou, F., Nagy, A., Yaniv, M. & Wagner, E. F., 2003, In : Development. 130, 1, p. 103-109 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Left main coronary artery ostial stenosis: The role of transoesophageal echocardiography

Nagy, A., Lakatos, F. & Lengyel, M., Jun 2003, In : Acta Cardiologica. 58, 3, p. 209-210 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model

Ding, H., Shannon, P., Lau, N., Wu, X., Roncari, L., Baldwin, R. L., Takebayashi, H., Nagy, A., Gutmann, D. H. & Guha, A., 1 Mar 2003, In : Cancer Research. 63, 5, p. 1106-1113 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Rap1 activity is elevated in malignant astrocytomas independent of tuberous sclerosis complex-2 gene expression.

Lau, N., Uhlmann, E. J., Von Lintig, F. C., Nagy, A., Boss, G. R., Gutmann, D. H. & Guha, A., Jan 2003, In : International journal of oncology. 22, 1, p. 195-200 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Role of the Rap1 GTPase in astrocyte growth regulation

Apicelli, A. J., Uhlmann, E. J., Baldwin, R. L., Ding, H., Nagy, A., Guha, A. & Gutmann, D. H., 1 May 2003, In : GLIA. 42, 3, p. 225-234 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Site-specific cassette exchange and germline transmission with mouse ES cells expressing φC31 integrase

Belteki, G., Gertsenstein, M., Ow, D. W. & Nagy, A., 1 Mar 2003, In : Nature Biotechnology. 21, 3, p. 321-324 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Supplementation-Dependent Differences in the Rates of Embryonic Stem Cell Self-Renewal, Differentiation, and Apoptosis

Viswanathan, S., Benatar, T., Mileikovsky, M., Lauffenburger, D. A., Nagy, A. & Zandstra, P. W., 5 Dec 2003, In : Biotechnology and Bioengineering. 84, 5, p. 505-517 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Tailoring the genome: The power of genetic approaches

Nagy, A., Perrimon, N., Sandmeyer, S. & Plasterk, R., 2003, In : Nature Genetics. 33, 3S, p. 276-284 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Targeted deletion of histidine decarboxylase gene in mice increases bone formation and protects against ovariectomy-induced bone loss

Fitzpatrick, L. A., Buzas, E., Gagne, T. J., Nagy, A., Horvath, C., Ferencz, V., Mester, A., Kari, B., Ruan, M., Falus, A. & Barsony, J., 13 May 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 10, p. 6027-6032 6 p.

Research output: Contribution to journalArticleResearchpeer-review

VEGF-A signaling in the glomerulus.

Eremina, V., Haigh, J., Nagy, A. & Quaggin, SE., 2003, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. Vol. 14. p. 25A-25A

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearch

2002

Accelerated clearance of Escherichia coli in experimental peritonitis of histamine-deficient mice

Hori, Y., Nihei, Y., Kurokawa, Y., Kuramasu, A., Makabe-Kobayashi, Y., Terui, T., Doi, H., Satomi, S., Sakurai, E., Nagy, A., Watanabe, T. & Ohtsu, H., 15 Aug 2002, In : Journal of Immunology. 169, 4, p. 1978-1983 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Bone marrow-derived mast cell differentiation is strongly reduced in histidine decarboxylase knockout, histamine-free mice

Wiener, Z., Andrásfalvy, M., Pállinger, É., Kovács, P., Szalai, C., Erdei, A., Tóth, S., Nagy, A. & Falus, A., 2002, In : International Immunology. 14, 4, p. 381-387 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Early restriction of peripheral and proximal cell lineages during formation of the lung

Perl, A. K. T., Wert, S. E., Nagy, A., Lobe, C. G. & Whitsett, J. A., Aug 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 16, p. 10482-10487 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Embryonic stem cells and mice expressing different GFP variants for multiple non-invasive reporter usage within a single animal

Hadjantonakis, A. K., MacMaster, S. & Nagy, A., 11 Jun 2002, In : BMC Biotechnology. 2, 11.

Research output: Contribution to journalArticleResearchpeer-review

ES cell-mediated conditional transgenesis.

Gertsenstein, M., Lobe, C. & Nagy, A., 2002, In : Methods in molecular biology (Clifton, N.J.). 185, p. 285-307 23 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer

Logan, M., Martin, J. F., Nagy, A., Lobe, C., Olson, E. N. & Tabin, C. J., 2002, In : Genesis. 33, 2, p. 77-80 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Gastric acid secretion in L-histidine decarboxylase-deficient mice

Tanaka, S., Hamada, K., Yamada, N., Sugita, Y., Tonai, S., Hunyady, B., Palkovits, M., Falus, A., Watanabe, T., Okabe, S., Ohtsu, H., Ichikawa, A. & Nagy, A., 2002, In : Gastroenterology. 122, 1, p. 145-155 11 p.

Research output: Contribution to journalArticleResearchpeer-review