1978 …2022
If you made any changes in Pure these will be visible here soon.

Research Output 1978 2019

2010

Hedgehog regulates distinct vascular patterning events through VEGF-dependent and -independent mechanisms

Coultas, L., Nieuwenhuis, E., Anderson, G. A., Cabezas, J., Nagy, A., Henkelman, R. M., Hui, C. C. & Rossant, J., 29 Jul 2010, In : Blood. 116, 4, p. 653-660 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Increased skeletal VEGF enhances Β-catenin activity and results in excessively ossified bones

Maes, C., Goossens, S., Bartunkova, S., Drogat, B., Coenegrachts, L., Stockmans, I., Moermans, K., Nyabi, O., Haigh, K., Naessens, M., Haenebalcke, L., Tuckermann, J. P., Tjwa, M., Carmeliet, P., Mandic, V., David, J. P., Behrens, A., Nagy, A., Carmeliet, G. & Haigh, J. J., Jan 2010, In : EMBO Journal. 29, 2, p. 424-441 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis

Xu, K., Nieuwenhuis, E., Cohen, B. L., Wang, W., Canty, A. J., Danska, J. S., Coultas, L., Rossant, J., Wu, M. Y. J., Piscione, T. D., Nagy, A., Gossler, A., Hicks, G. G., Hui, C. C., Henkelman, R. M., Yu, L. X., Sled, J. G., Gridley, T. & Egan, S. E., Jan 2010, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 298, 1

Research output: Contribution to journalArticleResearchpeer-review

Multifaceted role of vascular endothelial growth factor signaling in adult tissue physiology: An emerging concept with clinical implications

Sung, H. K., Michael, I. P. & Nagy, A., May 2010, In : Current Opinion in Hematology. 17, 3, p. 206-212 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Over-expression of Specific VEGF Isoforms Differentially Enhances and Patterns Bone Formation by Modulating Angiogenesis and Osteoblast Precursors

Maes, C., Bartunkova, S., Haigh, K., Torrekens, S., Van Looveren, R., Chan, A., Nagy, A., Haigh, J. & Carmeliet, G., 2010, In : Bone. 46, p. S53

Research output: Contribution to journalArticleResearch

Passaged human chondrocytes accumulate extracellular matrix when induced by bovine chondrocytes

Ahmed, N., Taylor, D. W., Wunder, J., Nagy, A., Gross, A. E. & Kandel, R. A., Mar 2010, In : Journal of Tissue Engineering and Regenerative Medicine. 4, 3, p. 233-241 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Production of mouse chimeras by aggregating pluripotent stem cells with embryos

Nagy, A., Nagy, K. & Gertsenstein, M., 2010, In : Methods in Enzymology. 476, C, p. 123-149 27 p.

Research output: Contribution to journalArticleResearchpeer-review

Stem cell therapy for the kidney: A cautionary tale

Nagy, A. & Quaggin, S. E., Jul 2010, In : Journal of the American Society of Nephrology. 21, 7, p. 1070-1072 3 p.

Research output: Contribution to journalEditorialOtherpeer-review

The mysteries of induced pluripotency: Where will they lead?

Nagy, A. & Nagy, K., Jan 2010, In : Nature Methods. 7, 1, p. 22-24 3 p.

Research output: Contribution to journalComment / DebateResearchpeer-review

Vascular endothelial growth factor - A positive and negative regulator of tumor growth

Vecchiarelli-Federico, L. M., Cervi, D., Haeri, M., Li, Y., Nagy, A. & Ben-David, Y., 1 Feb 2010, In : Cancer Research. 70, 3, p. 863-867 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Vegf regulates embryonic erythroid development through Gata1 modulation

Drogat, B., Kalucka, J., Gutiérrez, L., Hammad, H., Goossens, S., Ghahremani, M. F., Bartunkova, S., Haigh, K., Deswarte, K., Nyabi, O., Naessens, M., Ferrara, N., Klingmüller, U., Lambrecht, B. N., Nagy, A., Philipsen, S. & Haigh, J. J., 23 Sep 2010, In : Blood. 116, 12, p. 2141-2151 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Wnt/β-catenin signaling regulates postnatal development and regeneration of the salivary gland

Hai, B., Yang, Z., Millar, S. E., Choi, Y. S., Taketo, M. M., Nagy, A. & Liu, F., 1 Nov 2010, In : Stem Cells and Development. 19, 11, p. 1793-1801 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Zonadhesin is essential for species specificity of sperm adhesion to the egg zona pellucida

Tardif, S., Wilson, M. D., Wagner, R., Hunt, P., Gertsenstein, M., Nagy, A., Lobe, C., Koop, B. F. & Hardy, D. M., 6 Aug 2010, In : Journal of Biological Chemistry. 285, 32, p. 24863-24870 8 p.

Research output: Contribution to journalArticleResearchpeer-review

β-catenin initiates tooth neogenesis in adult rodent incisors

Liu, F., Dangaria, S., Andl, T., Zhang, Y., Wright, A. C., Damekpoprawa, M., Piccolo, S., Nagy, A., Taketo, M. M., Diekwisch, T. G. H., Akintoye, S. O. & Millar, S. E., Sep 2010, In : Journal of Dental Research. 89, 9, p. 909-914 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

Aggregation chimeras: Combining es cells, diploid, and tetraploid embryos

Tanaka, M., Hadjantonakis, A. K., Vintersten, K. & Nagy, A., 2009, Gene Knockout Protocols: Second Edition. Vol. 530. p. 287-309 23 p. (Methods in Molecular Biology; vol. 530).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Alternative Induced Pluripotent Stem Cell Characterization Criteria for In Vitro Applications

Ellis, J., Bruneau, B. G., Keller, G., Lemischka, I. R., Nagy, A., Rossant, J., Srivastava, D., Zandstra, P. W. & Stanford, W. L., 6 Mar 2009, In : Cell Stem Cell. 4, 3, p. 198-199 2 p.

Research output: Contribution to journalLetterResearchpeer-review

Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis

Adachi, H., Fujiwara, Y., Kondo, T., Nishikawa, T., Ogawa, R., Matsumura, T., Ishii, N., Nagai, R., Miyata, K., Tabata, M., Motoshima, H., Furukawa, N., Tsuruzoe, K., Kawashima, J., Takeya, M., Yamashita, S., Koh, G. Y., Nagy, A., Suda, T., Oike, Y. & 1 othersAraki, E., 20 Feb 2009, In : Biochemical and Biophysical Research Communications. 379, 4, p. 806-811 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Bone marrow transplantation results in human donor blood cells acquiring and displaying mouse recipient class I MHC and CD45 antigens on their surface

Yamanaka, N., Wong, C. J., Gertsenstein, M., Casper, R. F., Nagy, A. & Rogers, I. M., 2009, In : PLoS ONE. 4, 12, e8489.

Research output: Contribution to journalArticleResearchpeer-review

Cartilage tissue formation using redifferentiated passaged chondrocytes in vitro

Ahmed, N., Gan, L., Nagy, A., Zheng, J., Wang, C. & Kandel, R. A., 1 Mar 2009, In : Tissue Engineering - Part A. 15, 3, p. 665-673 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Creation and use of a cre recombinase transgenic database

Nagy, A., Mar, L. & Watts, G., 2009, Gene Knockout Protocols: Second Edition. Vol. 530. p. 365-378 14 p. (Methods in Molecular Biology; vol. 530).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells

Nyabi, O., Naessens, M., Haigh, K., Gembarska, A., Goossens, S., Maetens, M., De Clercq, S., Drogat, B., Haenebalcke, L., Bartunkova, S., De Vos, I., De Craene, B., Karimi, M., Berx, G., Nagy, A., Hilson, P., Marine, J. C. & Haigh, J. J., 2009, In : Nucleic Acids Research. 37, 7, e55.

Research output: Contribution to journalArticleResearchpeer-review

Human embryonic stem cells secrete soluble factors that inhibit cancer cell growth

Giuffrida, D., Rogers, I. M., Nagy, A., Calogero, A. E., Brown, T. J. & Casper, R. F., Dec 2009, In : Cell Proliferation. 42, 6, p. 788-798 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Krüppel-like factor 4, a "pluripotency transcription factor" highly expressed in male postmeiotic germ cells, is dispensable for spermatogenesis in the mouse

Godmann, M., Gashaw, I., Katz, J. P., Nagy, A., Kaestner, K. H. & Behr, R., Aug 2009, In : Mechanisms of Development. 126, 8-9, p. 650-664 15 p.

Research output: Contribution to journalArticleResearchpeer-review

PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

Woltjen, K., Michael, I. P., Mohseni, P., Desai, R., Mileikovsky, M., Hämäläinen, R., Cowling, R., Wang, W., Liu, P., Gertsenstein, M., Kaji, K., Sung, H. K. & Nagy, A., 9 Apr 2009, In : Nature. 458, 7239, p. 766-770 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Predictors of the outcome of thrombolytic therapy in prosthetic mitral valve thrombosis: A study of 62 events

Nagy, A., Dénes, M. & Lengyel, M., May 2009, In : Journal of Heart Valve Disease. 18, 3, p. 268-275 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The interval between Ins2 and Ascl2 is dispensable for imprinting centre function in the murine Beckwith-Wiedemann region

Lefebvre, L., Mar, L., Bogutz, A., Oh-McGinnis, R., Mandegar, M. A., Paderova, J., Gertsenstein, M., Squire, J. A. & Nagy, A., 2009, In : Human Molecular Genetics. 18, 22, p. 4255-4267 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Transposon-mediated genome manipulation in vertebrates

Ivics, Z., Li, M. A., Mátés, L., Boeke, J. D., Nagy, A., Bradley, A. & Izsvák, Z., 2009, In : Nature Methods. 6, 6, p. 415-422 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Virus-free induction of induced pluripotent stem cells

Nagy, A., 2009, In : Regenerative Medicine. 4, 3, p. 351-352 2 p.

Research output: Contribution to journalArticleResearchpeer-review

2008

Activation of β-catenin signaling programs embryonic epidermis to hair follicle fate

Zhang, Y., Andl, T., Yang, S. H., Teta, M., Liu, F., Seykora, J. T., Tobias, J. W., Piccolo, S., Schmidt-Ullrich, R., Nagy, A., Taketo, M. M., Dlugosz, A. A. & Millar, S. E., Jun 2008, In : Development. 135, 12, p. 2161-2172 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Alkaline phosphatase-positive colony formation is a sensitive, specific, and quantitative indicator of undifferentiated human embryonic stem cells

O'Connor, M. D., Kardel, M. D., Iosfina, I., Youssef, D., Lu, M., Li, M. M., Vercauteren, S., Nagy, A. & Eaves, C. J., May 2008, In : Stem Cells. 26, 5, p. 1109-1116 8 p.

Research output: Contribution to journalArticleResearchpeer-review

ARS2 is a conserved eukaryotic gene essential for early mammalian development

Wilson, M. D., Wang, D., Wagner, R., Breyssens, H., Gertsenstein, M., Lobe, C., Lu, X., Nagy, A., Burke, R. D., Koop, B. F. & Howard, P. L., Mar 2008, In : Molecular and Cellular Biology. 28, 5, p. 1503-1514 12 p.

Research output: Contribution to journalArticleResearchpeer-review

c-Myb-dependent smooth muscle cell differentiation

Kolodziejska, K. M., Noyan-Ashraf, M. H., Nagy, A., Bacon, A., Frampton, J., Xin, H. B., Kotlikoff, M. I. & Husain, M., Mar 2008, In : Circulation Research. 102, 5, p. 554-561 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Cre recombinase mediated alterations of the mouse genome using embryonic stem cells

Hadjantonakis, A. K., Pirity, M. & Nagy, A., 2008, Molecular Embryology: Methods and Protocols. Vol. 461. p. 111-132 22 p. (Methods in Molecular Biology; vol. 461).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7

Oh, R., Ho, R., Mar, L., Gertsenstein, M., Paderova, J., Hsien, J., Squire, J. A., Higgins, M. J., Nagy, A. & Lefebvre, L., Feb 2008, In : Molecular and Cellular Biology. 28, 3, p. 1092-1103 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Establishment of Endoderm Progenitors by SOX Transcription Factor Expression in Human Embryonic Stem Cells

Séguin, C. A., Draper, J. S., Nagy, A. & Rossant, J., 7 Aug 2008, In : Cell Stem Cell. 3, 2, p. 182-195 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Functional immobilization of signaling proteins enables control of stem cell fate

Alberti, K., Davey, R. E., Onishi, K., George, S., Salchert, K., Seib, F. P., Bornhäuser, M., Pompe, T., Nagy, A., Werner, C. & Zandstra, P. W., Jul 2008, In : Nature Methods. 5, 7, p. 645-650 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner

Purpura, K. A., George, S. H. L., Dang, S. M., Choi, K., Nagy, A. & Zandstra, P. W., Nov 2008, In : Stem Cells. 26, 11, p. 2832-2842 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The Use of Fresh Embryos in Stem Cell Research: Ethical and Policy Issues

Cohen, C. B., Brandhorst, B., Nagy, A., Leader, A., Dickens, B., Isasi, R. M., Evans, D. & Knoppers, B. M., 8 May 2008, In : Cell Stem Cell. 2, 5, p. 416-421 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

Autocrine VEGF Signaling Is Required for Vascular Homeostasis

Lee, S., Chen, T. T., Barber, C. L., Jordan, M. C., Murdock, J., Desai, S., Ferrara, N., Nagy, A., Roos, K. P. & Iruela-Arispe, M. L., 24 Aug 2007, In : Cell. 130, 4, p. 691-703 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

Adewumi, O., Aflatoonian, B., Ahrlund-Richter, L., Amit, M., Andrews, P. W., Beighton, G., Bello, P., Benvenisty, N., Berry, L. S., Bevan, S., Blum, B., Brooking, J., Chen, K. G., Choo, A. BH., Churchill, G. A., Corbel, M., Damjanov, I., Draper, J. S., Dvorak, P., Emanuelsson, K. & 65 othersFleck, R. A., Ford, A., Gertow, K. A. M., Gertsenstein, M., Gokhale, P. J., Hamilton, R. S., Hampl, A., Healy, L. E., Hovatta, O., Hyllner, J., Imreh, M. P., Itskovitz-Eldor, J., Jackson, J., Johnson, J., Jones, M., Kee, K., King, B. L., Knowles, B. B., Lako, M., Lebrin, F., Mallon, B. S., Manning, D., Mayshar, Y., McKay, R., Michalska, A. E., Mikkola, M., Mileikovsky, M., Minger, S. L., Moore, H. D., Mummery, C. L., Nagy, A., Nakatsuji, N., O'Brien, C., Oh, S. K., Olsson, C., Otonkoski, T., Park, K-Y., Passier, R., Patel, H., Patel, M., Pedersen, R., Pera, M. F., Piekarczyk, M. S., Reijo Pera, R. A., Reubinoff, B. E., Robins, A. J., Rossant, J., Rugg-Gunn, P., Schulz, T. C., Semb, H., Sherrer, E. S., Siemen, H., Stacey, G. N., Stojkovic, M., Suemori, H., Szatkiewicz, J., Turetsky, T., Tuuri, T., van den Brink, S., Vintersten, K., Vuoristo, S., Ward, D., Weaver, T. A., Young, L. A. & Zhang, W., 2007, In : Nature Biotechnology. 25, 7, p. 803 - 816 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Developmental and adult phenotyping directly from mutant embryonic stem cells

George, S. HL., Gertsenstein, M., Vintersten, K., Korets-Smith, E., Murphy, J., Stevens, M. E., Haigh, J. J. & Nagy, A., 2007, In : Proceedings of the National Academy of Sciences. 104, 11, p. 4455-4460 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhanced natural-killer cell and erythropoietic activities in VEGF-A--overexpressing mice delay F-MuLV--induced erythroleukemia

Cervi, D., Shaked, Y., Haeri, M., Usenko, T., Lee, C. R., Haigh, J. J., Nagy, A., Kerbel, R. S., Yefenof, E. & Ben-David, Y., 2007, In : Blood. 109, 5, p. 2139-2146 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Glycogen Synthase Kinase 3α-Specific Regulation of Murine Hepatic Glycogen Metabolism

MacAulay, K., Doble, B. W., Patel, S., Hansotia, T., Sinclair, E. M., Drucker, D. J., Nagy, A. & Woodgett, J. R., 3 Oct 2007, In : Cell Metabolism. 6, 4, p. 329-337 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Improved embryonic stem cell technologies

Drape, J. S. & Nagy, A., 2007, Conditional Mutagenesis: An Approach to Disease Models. Vol. 178. p. 107-128 22 p. (Handbook of Experimental Pharmacology; vol. 178).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Niche-mediated control of human embryonic stem cell self-renewal and differentiation

Peerani, R., Rao, B. M., Bauwens, C., Yin, T., Wood, G. A., Nagy, A., Kumacheva, E. & Zandstra, P. W., 14 Nov 2007, In : EMBO Journal. 26, 22, p. 4744-4755 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

Basic Science Articles-Pathophysiology of Renal Disease and Progression-Vascular Endothelial Growth Factor A Signaling in the Podocyte-Endothelial Compartment Is Required for Mesangial Cell

Eremina, V., Cui, S., Gerber, H., Ferrara, N., Haigh, J., Nagy, A., Ema, M., Rossant, J., Jothy, S. & Miner, J. H., 2006, In : Journal of the American Society of Nephrology. 17, 3, p. 724-735 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Murine Embryonic Stem Cells

Nagy, A. & Vintersten, K., 2006, In : Methods in Enzymology. 418, p. 3-21 19 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Nuclear transfer reprogramming does not improve the low developmental potency of embryonic stem cells induced by long-term culture

Amano, T., Gertsenstein, M., Nagy, A., Kurihara, H. & Suzuki, H., Aug 2006, In : Reproduction. 132, 2, p. 257-263 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Placental but not heart defects are associated with elevated hypoxia-inducible factor α levels in mice lacking prolyl hydroxylase domain protein 2

Takeda, K., Ho, V. C., Takeda, H., Duan, L. J., Nagy, A. & Fong, G. H., Nov 2006, In : Molecular and Cellular Biology. 26, 22, p. 8336-8346 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The effect of different VEGF isoforms on mesoderm in the early mouse embryo

van George, S., Chan, A., Haigh, J. & Nagy, A., 2006, In : Vascular Pharmacology. 45, 3, p. e39-e40

Research output: Contribution to journalArticleResearch