Projects per year
Personal profile
Biography
Dr Winship is an Australian Research Council DECRA Fellow (2021-2023) in the Ovarian Biology Laboratory at Monash Biomedicine Discovery Institute.
She obtained her PhD in 2016 at the Hudson Institute of Medical Research, focused on defining the role of cytokines in the female reproductive tract (PNAS 2015; https://doi.org/10.1073/pnas.1515076112) and reproductive cancer.
Her current research examines the essential role of DNA repair capacity in regulating quality control of the female germline (Human Reproduction Update 2018; https://doi.org/10.1093/humupd/dmy002). She recently revealed the first evidence for a key role of intrinsic DNA break repair in response to endogenous DNA damage (i.e. resulting from normal cellular processes) to safeguard primordial oocyte number, genetic integrity and reproductive capacity (Human Reproduction 2020; https://doi.org/10.1093/humrep/deaa128).
Additionally, she is establishing her own research niche, capitalising on her background in uterine and placental biology, as well as oncofertility. This research addresses a fundamental knowledge gap, largely ignored by the fertility preservation field – do cancer therapies damage the uterus? (Human Reproduction Update 2020; https://doi.org/10.1093/humupd/dmz041, Human Reproduction Open 2020; https://doi.org/10.1093/hropen/hoaa045)
Her research is highly relevant to population health in Australia in context of fertility of female cancer survivors and maternal ageing.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research area keywords
- Female reproduction
- Fertility Preservation
- Ovary
- Oocytes
- Uterus
- Endometrium
- Pregnancy
- DNA repair
Network
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Survivorship Sequelae of Precision Breast Cancer Treatments: Defining the impacts of immunotherapy and PARP inhibitors on ovarian function and fertility
Hutt, K., Phillips, K. A., Loi, S., Winship, A. & Cui, W.
National Breast Cancer Foundation
23/03/22 → 31/12/24
Project: Research
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Defining single-strand DNA break repair capacity in oocytes
Australian Research Council (ARC)
1/01/21 → 31/12/23
Project: Research
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SCIREQ inExpose system
Winship, A., Carroll, J., Bourke, J., Simonds, S., Heng, T., Hutt, K., Stringer, J., Western, P., Coelho Marques, F. & Abud, H.
1/10/21 → 31/12/22
Project: Research
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Fertility Preservation for Cancer Survivors: Optimising the dose of PUMA inhibitor for ovarian protection using LC-MS/MS
9/08/21 → 31/12/21
Project: Research
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Beyond apoptosis: evidence of other regulated cell death pathways in the ovary throughout development and life
Stringer, J., Alesi, L. R., Winship, A. & Hutt, K., 2023, (Accepted/In press) In: Human Reproduction Update. p. 1-23 23 p., dmad005.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access -
IL11 activates the placental inflammasome to drive preeclampsia
Menkhorst, E., Santos, L. L., Zhou, W., Yang, G., Winship, A., Rainczuk, K., Nguyen, P., Zhang, J-G., Moore, P., Williams, M., Cao, K. A. L., Mansell, A. & Dimitriadis, E., 2023, In: Frontiers in Immunology. 14, 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
Griffiths, M. J., Higgins, J. N., Cousins, F. L., Alesi, L. R., Winship, A. L. & Hutt, K. J., Apr 2023, In: Journal of Visualized Experiments. 194, 14 p., e64763.Research output: Contribution to journal › Article › Other › peer-review
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Radiotherapy exposure directly damages the uterus and causes pregnancy loss
Griffiths, M. J., Marshall, S. A., Cousins, F. L., Alesi, L. R., Higgins, J., Giridharan, S., Sarma, U. C., Menkhorst, E., Zhou, W., Care, A. S., Donoghue, J. F., Holdsworth-Carson, S. J., Rogers, P. AW., Dimitriadis, E., Gargett, C. E., Robertson, S. A., Winship, A. L. & Hutt, K. J., 22 Mar 2023, In: JCI Insight. 8, 6, 21 p., e163704.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
The future of fertility preservation for women treated with chemotherapy
Alesi, L. R., Nguyen, Q-N., Stringer, J., Winship, A. & Hutt, K., 2023, In: Reproduction and Fertility. 4, 2, 22 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
Prizes
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Australia and New Zealand Placental Associations New Investigator Travel Award, AUD$500
Winship, Amy (Recipient), 2015
Prize: Prize (including medals and awards)
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Australian Society for Medical Research Victorian Student Symposium Oral Presentation Award, AUD$120
Winship, Amy (Recipient), 2013
Prize: Prize (including medals and awards)
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Harold Mitchell Foundation PhD Student Travel Fellowship, AUD$5000
Winship, Amy (Recipient), 2015
Prize: Prize (including medals and awards)
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Hudson Institute Centre for Reproductive Health Postdoctoral Travel Award, AUD$2500
Winship, Amy (Recipient), 2016
Prize: Prize (including medals and awards)
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Hudson Institute Student Excellence Travel Award, AUD$1500
Winship, Amy (Recipient), 2014
Prize: Prize (including medals and awards)
Press/Media
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Future Science Early Career Interview: Amy Winship
3/05/19
1 Media contribution
Press/Media: Profile/Interview
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Herald Sun News Article: Mum's diet before pregnancy affects daughter's pregnancy chances
27/10/17
1 Media contribution
Press/Media: Article/Feature
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RRR 'Einstein A Go-Go' Radio Program Interview
4/06/17
1 Media contribution
Press/Media: Expert Comment
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ABC Drive Radio: Uncovering a potential cause and cure for preeclampsia
11/04/17
1 Media contribution
Press/Media: Expert Comment
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Herald Sun News Article: Villain protein may be saviour
11/04/17
1 Media contribution
Press/Media: Article/Feature