Projects per year
Alan Trounson is Emeritus Professor Monash University and Distinguished Scientist, Hudson Institute for Medical Research, Clayton, Victoria, Australia. He is the past President of the Californian Institute for Regenerative Medicine (2007-2014) the Californian state’s $3 billion stem cell agency driving research in stem cell biology and facilitating the translation of stem cell discoveries into clinical therapies.
He was a pioneer of human in vitro fertilisation (IVF) (1977-1996), introducing fertility drugs for controlling ovulation, embryo freezing techniques, egg and embryo donation methods, early sperm microinjection methods, initiated embryo biopsy, developing in vitro oocyte maturation methods and the vitrification of eggs and embryos.
He was appointed Director of the Centre for Early Human Development at Monash University in 1986 and Deputy Director/Director of the Monash Institute for Reproduction and Development (1990-2003) He led the Australian team for the discovery of human embryonic stem cells in the late 1990’s and was awarded the first Australian Biotechnology of Excellence and was the founding CEO of the Australian Stem Cell Centre. He founded the Monash Immunology and Stem Cell Laboratories (MISCL) at Monash University (2004-7)
He is presently the founding CEO/President of the start-up company Cartherics Pty Ltd developing Chimeric Antigen Receptor Technology (CAR-T)/T Cell Receptor (TCR) therapies using induced Pluripotent Stem Cells (iPSCs) as an off-the shelf approach for treating cancer. Cartherics is sited on the 7th Floor of the Translation Research Facility Building, Monash Medical Centre, Clayton, Victoria.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
CEO, Cartherics Pty Ltd
Research area keywords
- Stem Cell Therapy
- Immune System
- Cancer Therapeutics
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Induced pluripotent stem cell derived cardiomyocytes: a new therapy for “no-option” end stage heart failure
Chong, J. J. H., Chow, C., Gray, P., Trounson, A., Palpant, N. J., Graham, R., McDonald, P. & Shiba, Y.
1/03/22 → 29/03/27
The establishment of a joint Australia-China centre for excellence in stem cell science
Boyd, R., Bernard, C., Chidgey, A., Elefanty, A., Jenkin, G., Li, L., Li, Y., Li, L., Lin, C., Ricardo, S., Shen, L., Stanley, E., Trounson, A., Wallace, E., Wang, L., Wen, J. & Zhou, S.
Department of Employment and Workplace Relations (Australia)
Allogeneic Stem Cell Cancer Immunotherapies
31/01/18 → 30/11/22
High Content Cell Signaling Discovery and Screening Facility
Hertzog, P., Adler, B., Berndt, M., Sexton, P., Trounson, A. & Williams, B.
Australian Research Council (ARC), Monash University, Victorian Infectious Diseases Reference Laboratory
17/03/08 → 31/12/08
Why it is important to study human–monkey embryonic chimeras in a dishDe Los Angeles, A., Regenberg, A., Mascetti, V., Benvenisty, N., Church, G., Deng, H., Izpisua Belmonte, J. C., Ji, W., Koplin, J., Loh, Y. H., Niu, Y., Pei, D., Pera, M., Pho, N., Pinzon-Arteaga, C., Saitou, M., Silva, J. C. R., Tao, T., Trounson, A., Warrier, T., & 1 others, Aug 2022, In: Nature Methods. 19, 8, p. 914-919 6 p.
Research output: Contribution to journal › Comment / Debate › Other › peer-review
Engineered CAR-T cells targeting TAG-72 and CD47 in ovarian cancerShu, R., Evtimov, V. J., Hammett, M. V., Nguyen, N. Y. N., Zhuang, J., Hudson, P. J., Howard, M. C., Pupovac, A., Trounson, A. O. & Boyd, R. L., 26 Mar 2021, In: Molecular Therapy - Oncolytics. 20, p. 325-341 17 p.
Research output: Contribution to journal › Article › Research › peer-reviewOpen Access
Enhancing a natural killer: Modification of nk cells for cancer immunotherapyIslam, R., Pupovac, A., Evtimov, V., Boyd, N., Shu, R., Boyd, R. & Trounson, A., May 2021, In: Cells. 10, 5, 31 p., 1058.
Research output: Contribution to journal › Review Article › Research › peer-reviewOpen Access
Off-the-shelf ipsc derived car-nk immunotherapy for solid tumorsBoyd, N. R., Tiedemann, M., Cartledge, K., Cao, M., Evtimov, V. J., Shu, R., Nguyen, T., Nguyen, N., Nisbet, I. T., Boyd, R. & Trounson, A., May 2020, In: Cytotherapy. 22, 5S3, p. S199 1 p., 416.
Research output: Contribution to journal › Meeting Abstract › peer-review
Improving access to ART in low-income settings through knowledge transfer: a case study from ZimbabweHammarberg, K., Trounson, A., McBain, J., Matthews, P., Robertson, T., Robertson, F., Magli, C., Mhlanga, T., Makurumure, T. & Marechera, F., 1 Sep 2018, In: Human Reproduction Open. 8, 4, p. 1-5 5 p., hoy017.
Research output: Contribution to journal › Article › Research › peer-reviewOpen AccessFile