Alan Trounson

Emeritus Prof

1989 …2022
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Personal profile

Biography

Biography

Alan Trounson is Emeritus Professor Monash University and Distinguished Scientist, Hudson Institute for Medical Research, Clayton, Victoria, Australia. He is the past President of the Californian Institute for Regenerative Medicine (2007-2014) the Californian state’s $3 billion stem cell agency driving research in stem cell biology and facilitating the translation of stem cell discoveries into clinical therapies.

He was a pioneer of human in vitro fertilisation (IVF) (1977-1996), introducing fertility drugs for controlling ovulation, embryo freezing techniques, egg and embryo donation methods, early sperm microinjection methods, initiated embryo biopsy, developing in vitro oocyte maturation methods and the vitrification of eggs and embryos.

He was appointed Director of the Centre for Early Human Development at Monash University in 1986 and Deputy Director/Director of the Monash Institute for Reproduction and Development (1990-2003) He led the Australian team for the discovery of human embryonic stem cells in the late 1990’s and was awarded the first Australian Biotechnology of Excellence and was the founding CEO of the Australian Stem Cell Centre. He founded the Monash Immunology and Stem Cell Laboratories (MISCL) at Monash University (2004-7)

He is presently the founding CEO/President of the start-up company Cartherics Pty Ltd developing Chimeric Antigen Receptor Technology (CAR-T)/T Cell Receptor (TCR) therapies using induced Pluripotent Stem Cells (iPSCs) as an off-the shelf approach for treating cancer. Cartherics is sited on the 7th Floor of the Translation Research Facility Building, Monash Medical Centre, Clayton, Victoria.

External positions

CEO, Cartherics Pty Ltd

Keywords

  • Stem Cell Therapy
  • Immune System
  • Cancer Therapeutics

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Projects 2000 2022

Research Output 1989 2017

Combining hiPSCs and Human Genetics: Major Applications in Drug Development

Zhang, J., Li, H., Trounson, A., Wu, J. C. & Nioi, P. 3 Aug 2017 In : Cell Stem Cell. 21, 2, p. 161-165 5 p.

Research output: Contribution to journalComment / Debate

Potential pitfall of pluripotent stem cells

Trounson, A. 3 Aug 2017 In : New England Journal of Medicine. 377, 5, p. 490-491 2 p.

Research output: Contribution to journalShort Survey

Preferential selection and transfer of euploid noncarrier embryos in preimplantation genetic diagnosis cycles for reciprocal translocations

Wang, L., Shen, J., Cram, D. S., Ma, M., Wang, H., Zhang, W., Fan, J., Gao, Z., Zhang, L., Li, Z., Xu, M., Leigh, D. A., Trounson, A. O., Liu, J. & Yao, Y. Oct 2017 In : Fertility and Sterility. 108, 4, p. 620-627 8 p.

Research output: Contribution to journalArticle

Pluripotent stem cells progressing to the clinic

Trounson, A. & DeWitt, N. D. 1 Mar 2016 In : Nature Reviews Molecular Cell Biology. 17, 3, p. 194-200 7 p.

Research output: Contribution to journalReview Article

Development of a global network of induced pluripotent stem cell haplobanks

Wilmut, I., Leslie, S., Martin, N. G., Peschanski, M., Rao, M. S., Trounson, A., Turner, D., Turner, M. L., Yamanaka, S. & Taylor, C. J. 1 May 2015 In : Regenerative Medicine. 10, 3, p. 235-238 4 p.

Research output: Contribution to journalEditorial