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Agustin Cota Cota Coronado

Dr

Accepting PhD Students

PhD projects

1. Limiting prenatal inflammation from a COVID-19-like Cytokine Storm to protect against Neurodevelopmental Disorder risk<br/>2. Identifying new targets and molecules for depression and the potential prevention of suicide risk using 'brain-on-a-chip' stem cell-derived platforms<br/>3. Understanding the molecular basis of schizophrenia in advance human stem cell-derived neuronal cultures<br/>

20162025

Research activity per year

Personal profile

Biography

I am the inaugural Depression and Suicide Prevention Research Fellow (One in Five; 2024–2026) and Lead of the Human Stem Cell Laboratory in the Department of Psychiatry at Monash University (EMCR, five years post-PhD). I have established independent research capacity through the development of two human stem cell facilities at Monash University and the University of Copenhagen, secured over ~AUD $500,000.00 as Chief Investigator ~in competitive funding (One in Five; HOMER Hack Foundation; NHMRC; MJFF), and built an internationally networked program spanning stem cell biology and translational psychiatry. My track record includes first- and corresponding-author publications, patents with commercial potential, invited teaching, and supervision of PhD, Masters, and Honours trainees.

My leadership has been recognised with major awards at leading international conferences, including ISSCR, Hong Kong (Zhongmei Chen Yong Award for Scientific Excellence, 2025) and 4D Organoid, Osaka (Outstanding Research Prize, 2026).

My research addresses a central challenge in psychiatry: the lack of human-specific experimental systems capable of resolving causal neurodevelopmental mechanisms. I develop pluripotent stem cell–derived platforms, including organ-on-a-chip technologies, to model how genetic and environmental risk factors, particularly how prenatal inflammation alters human brain development and its link to disorders such as schizophrenia, depression, and autism.

By integrating these systems with single-cell multi-omics, I define mechanistically convergent pathways with direct translational relevance. Supported by established infrastructure and collaborations with institutions including: Southern Denmark University (SDU), Stanford University, the University of Copenhagen (UCPH), the University of Sydney (USYD), and the University of Wollongong (UoW), my program combines mechanistic discovery with systematic drug repurposing of clinically approved compounds. This strategy delivers scalable human models, prioritised therapeutic targets, and a competitive funding pipeline, positioning my work to advance precision psychiatry and accelerate clinical impact.

Education/Academic qualification

Neuroscience, PhD Medical Biotechnology, Regenerative Medicine, Neuroscience, Generation of cellular models of Parkinson´s Disease from induced pluripotent Stem Cells (iPSCs) for drug discovery and gene-therapy applications., Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco (Center for Research and Assistance in Technology and Design of the State of Jalisco)

Award Date: 20 Aug 2020

Neurodegenerative Diseases, Stem Cells, Post-doctoral Fellow, Understanding the selective vulnerability of midbrain dopaminergic neurons in Parkinson's disease, Københavns Universitet (University of Copenhagen)

23 Feb 202120 Feb 2023

Research area keywords

  • Stem Cells
  • Psychiatry
  • neuronal population
  • Disease model development
  • neurodegeneration
  • Schizophrenia

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Collaborations and top research areas from the last five years

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