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Personal profile

Biography

Dr Adam Rose studied Exercise Science at Griffith University. He went on to complete an Honours degree and PhD at Deakin University with Prof. Mark Hargreaves studying exercise metabolism, biochemistry and skeletal muscle signalling. He conducted his junior post-doctoral training with Prof. Erik Richter at Copenhagen University continuing on studies of skeletal muscle signalling, adaptation and metabolism. He then joined Prof. Stephan Herzig at the German Cancer Research Center as a Senior Scientist and subsequent Sub-Group Leader studying liver metabolic-hormonal signalling and systemic metabolic control in health and disease. He joined Monash University in August 2017 as a Senior Research Fellow and Head of the Nutrient Metabolism and Signalling Laboratory within the Dept. of Biochemistry and Molecular Biology as part of the Biomedicine Discovery Institute Metabolism, Diabetes and Obesity Program.

Research interests

In general, we adopt an integrated systems approach to further the understanding of adaptive/maladaptive metabolism and the molecular mechanisms involved therein, with the eventual aim to discover new therapies for diseases with a metabolic basis such as obesity, diabetes, and perhaps cancer. Our particular interest lies in the complex interaction between nutrients, hormones, and signalling pathways which connect these to ultimately coordinate systemic metabolic control. Our particular projects aim to further understand:

1. Nutrient-hormonal-signalling nodes controlling metabolic homeostasis
2. Stress-signalling pathways in adaptive metabolic control
3. Inter-organ metabolic cross-talk in health and disease

Supervision interests

We are continually seeking motivated and talented people to join our group to synergise with the team to make new and exciting discoveries in metabolism. For unsolicited applications email: adam.rose@monash.edu

PhD Scholarship opportunities
Multiple projects available. We attempt to tailor the project to the student after presentation of the research topic backgrounds and ideas. We typically conduct whole animal metabolic physiology as well as cell/tissue culture using genetic and viral-transduction approaches to conduct gain-and loss-of-function experiments.

Candidate requirements
Candidates with a background in physiology or biochemistry/molecular biology with a strong interest in our topic are encouraged to apply. Candidates with, or in the process of completing, an experimental background in Physiology or Biochemistry/Molecular Biology should have H1 honours degree or equivalent. Students intending to apply for competitive scholarships /fellowships should contact Dr. Rose directly.

Availability
One PhD scholarship position is currently available.

Honours project opportunities

2017 Honours Booklet

Applications
To apply, please ensure to include with your application:
• A cover letter including a brief outline detailing your intestest and suitability
• A detailed CV/resume including academic transcripts
• Names and contact details of two referees

Email all applications to adam.rose@monash.edu

Keywords

  • metabolism, stress signalling, nutrition, exercise, obesity, diabetes, liver, muscle, hormones, adaptation

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2001 2019

Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance

Maida, A., Zota, A., Vegiopoulos, A., Appak-Baskoy, S., Augustin, H. G., Heikenwalder, M., Herzig, S. & Rose, A. J., 1 Jul 2018, In : Journal of Nutritional Biochemistry. 57, p. 189-196 8 p.

Research output: Contribution to journalArticleResearchpeer-review

A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution

Maida, A., Zota, A., Sjøberg, K. A., Schumacher, J., Sijmonsma, T. P., Pfenninger, A., Christensen, M. M., Gantert, T., Fuhrmeister, J., Rothermel, U., Schmoll, D., Heikenwälder, M., Iovanna, J. L., Stemmer, K., Kiens, B., Herzig, S. & Rose, A. J., 1 Sep 2016, In : Journal of Clinical Investigation. 126, 9, p. 3263-3278 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health

Fuhrmeister, J., Zota, A., Sijmonsma, T. P., Seibert, O., Cingir, Ş., Schmidt, K., Vallon, N., de Guia, R. M., Niopek, K., Berriel Diaz, M., Maida, A., Blüher, M., Okun, J. G., Herzig, S. & Rose, A. J., 1 Jun 2016, In : EMBO Molecular Medicine. 8, 6, p. 654-669 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Molecular regulation of urea cycle function by the liver glucocorticoid receptor

Okun, J. G., Conway, S., Schmidt, K. V., Schumacher, J., Wang, X., de Guia, R., Zota, A., Klement, J., Seibert, O., Peters, A., Maida, A., Herzig, S. & Rose, A. J., 1 Oct 2015, In : Molecular Metabolism. 4, 10, p. 732-740 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Molecular control of systemic bile acid homeostasis by the liver glucocorticoid receptor

Rose, A. J., Díaz, M. B., Reimann, A., Klement, J., Walcher, T., Krones-Herzig, A., Strobel, O., Werner, J., Peters, A., Kleyman, A., Tuckermann, J. P., Vegiopoulos, A. & Herzig, S., 6 Jul 2011, In : Cell Metabolism. 14, 1, p. 123-130 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Prizes

Copenhagen Muscle Research Centre Presentation prize

Adam Rose (Recipient), 2005

Prize: Other distinction

Copenhagen Muscle Research Centre Presentation prize

Adam Rose (Recipient), 2006

Prize: Other distinction

FASEB SRC Poster presentation award

Adam Rose (Recipient), 2012

Prize: Prize (including medals and awards)

FASEB SRC Presenter award

Adam Rose (Recipient), 2015

Prize: Prize (including medals and awards)

Griffith University Award for Academic Excellence

Adam Rose (Recipient), 1998

Prize: Other distinction

Activities 2005 2005

  • 1 Peer review responsibility

Journal of Applied Physiology (Journal)

Adam Rose (Peer reviewer)
20052007

Activity: Publication peer-review and editorial work typesPeer review responsibility