20122019
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Research Output 2012 2019

  • 7 Article
  • 1 Chapter (Book)
  • 1 Review Article
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Article
2019

Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes

Yuan, Y., Ayinuola, Y. A., Singh, D., Ayinuola, O., Mayfield, J. A., Quek, A., Whisstock, J. C., Law, R. H. P., Lee, S. W., Ploplis, V. A. & Castellino, F. J., 1 Oct 2019, In : Journal of Structural Biology. 208, p. 18-29 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding

Quek, A. J. H., Mazzitelli, B. A., Wu, G., Leung, E. W. W., Caradoc-Davies, T. T., Lloyd, G. J., Jeevarajah, D., Conroy, P. J., Sanderson-Smith, M., Yuan, Y., Ayinuola, Y. A., Castellino, F. J., Whisstock, J. C. & Law, R. H. P., 6 Sep 2019, In : Journal of Molecular Biology. 431, 19, p. 3804-3813 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator

Wu, G., Mazzitelli, B. A., Quek, A. J., Veldman, M. J., Conroy, P. J., Caradoc-Davies, T. T., Ooms, L. M., Tuck, K. L., Schoenecker, J. G., Whisstock, J. C. & Law, R. H. P., 12 Mar 2019, In : Blood Advances. 3, 5, p. 729-733 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2017
6 Citations (Scopus)

X-ray crystal structure of plasmin with tranexamic acid–derived active site inhibitors

Law, R. H. P., Wu, G., Leung, E. W. W., Hidaka, K., Quek, A. J., Caradoc-Davies, T. T., Jeevarajah, D., Conroy, P. J., Kirby, N. M., Norton, R. S., Tsuda, Y. & Whisstock, J. C., 9 May 2017, In : Blood Advances. 1, 12, p. 766-771 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2015
2 Citations (Scopus)

Preferential acquisition and activation of plasminogen glycoform II by PAM positive group A streptococcal isolates

De Oliveira, D. M. P., Law, R. H. P., Ly, D., Cook, S. M., Quek, A. J., McArthur, J. D., Whisstock, J. C. & Sanderson-Smith, M. L., 2015, In : Biochemistry. 54, 25, p. 3960 - 3968 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2014
7 Citations (Scopus)

Dimerization is not a determining factor for functional high affinity human plasminogen binding by the group A streptococcal virulence factor PAM and is mediated by specific residues within the PAM a1a2 domain

Bhattacharya, S., Liang, Z., Quek, A. J., Ploplis, V., Law, R. H. P. & Castellino, F. J., 2014, In : Journal of Biological Chemistry. 289, 31, p. 21684 - 21693 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2012
107 Citations (Scopus)

The x-ray crystal structure of full-length human plasminogen

Law, R. HP., Caradoc-Davies, T. T., Cowieson, N. P., Horvath, A. J., Quek, A. J., Amarante Da Encarnacao, J., Steer, D. L., Cowan, A. D., Zhang, Q., Lu, B. GC., Pike, R. N., Smith, A. I., Coughlin, P. B. & Whisstock, J. C., 2012, In : Cell Reports. 1, 3, p. 185 - 190 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access