20122020
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Research Output 2012 2020

  • 9 Article
  • 1 Chapter (Book)
  • 1 Review Article
2020

Gas-Generating, pH-Responsive Calcium Carbonate Hybrid Particles with Biomimetic Coating for Contrast-Enhanced Ultrasound Imaging

Vidallon, M. L. P., Douek, A. M., Quek, A., McLiesh, H., Kaslin, J., Tabor, R. F., Bishop, A. I. & Teo, B. M., 1 Jan 2020, (Accepted/In press) In : Particle and Particle Systems Characterization. 37, 2, 8 p., 1900471.

Research output: Contribution to journalArticleResearchpeer-review

2019

Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes

Yuan, Y., Ayinuola, Y. A., Singh, D., Ayinuola, O., Mayfield, J. A., Quek, A., Whisstock, J. C., Law, R. H. P., Lee, S. W., Ploplis, V. A. & Castellino, F. J., 1 Oct 2019, In : Journal of Structural Biology. 208, p. 18-29 12 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Structural studies of plasmin inhibition

Wu, G., Quek, A. J., Caradoc-Davies, T. T., Ekkel, S. M., Mazzitelli, B., Whisstock, J. C. & Law, R. H. P., 5 Mar 2019, In : Biochemical Society Transactions. 47, 2, p. 541-557 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding

Quek, A. J. H., Mazzitelli, B. A., Wu, G., Leung, E. W. W., Caradoc-Davies, T. T., Lloyd, G. J., Jeevarajah, D., Conroy, P. J., Sanderson-Smith, M., Yuan, Y., Ayinuola, Y. A., Castellino, F. J., Whisstock, J. C. & Law, R. H. P., 6 Sep 2019, In : Journal of Molecular Biology. 431, 19, p. 3804-3813 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Toward Better Understanding on How Group A Streptococcus Manipulates Human Fibrinolytic System

Quek, A. J. H., Whisstock, J. C. & Law, R. H. P., 16 Aug 2019, Staphylococcus and Streptococcus. Kirmusaoglu, S. (ed.). IntechOpen Limited, 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Open Access
File
2 Citations (Scopus)

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator

Wu, G., Mazzitelli, B. A., Quek, A. J., Veldman, M. J., Conroy, P. J., Caradoc-Davies, T. T., Ooms, L. M., Tuck, K. L., Schoenecker, J. G., Whisstock, J. C. & Law, R. H. P., 12 Mar 2019, In : Blood Advances. 3, 5, p. 729-733 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2017
6 Citations (Scopus)

X-ray crystal structure of plasmin with tranexamic acid–derived active site inhibitors

Law, R. H. P., Wu, G., Leung, E. W. W., Hidaka, K., Quek, A. J., Caradoc-Davies, T. T., Jeevarajah, D., Conroy, P. J., Kirby, N. M., Norton, R. S., Tsuda, Y. & Whisstock, J. C., 9 May 2017, In : Blood Advances. 1, 12, p. 766-771 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2015
2 Citations (Scopus)

Preferential acquisition and activation of plasminogen glycoform II by PAM positive group A streptococcal isolates

De Oliveira, D. M. P., Law, R. H. P., Ly, D., Cook, S. M., Quek, A. J., McArthur, J. D., Whisstock, J. C. & Sanderson-Smith, M. L., 2015, In : Biochemistry. 54, 25, p. 3960 - 3968 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2014
7 Citations (Scopus)

Dimerization is not a determining factor for functional high affinity human plasminogen binding by the group A streptococcal virulence factor PAM and is mediated by specific residues within the PAM a1a2 domain

Bhattacharya, S., Liang, Z., Quek, A. J., Ploplis, V., Law, R. H. P. & Castellino, F. J., 2014, In : Journal of Biological Chemistry. 289, 31, p. 21684 - 21693 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2012
107 Citations (Scopus)

The x-ray crystal structure of full-length human plasminogen

Law, R. HP., Caradoc-Davies, T. T., Cowieson, N. P., Horvath, A. J., Quek, A. J., Amarante Da Encarnacao, J., Steer, D. L., Cowan, A. D., Zhang, Q., Lu, B. GC., Pike, R. N., Smith, A. I., Coughlin, P. B. & Whisstock, J. C., 2012, In : Cell Reports. 1, 3, p. 185 - 190 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access