20122019
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Research Output 2012 2019

Structural studies of plasmin inhibition

Wu, G., Quek, A. J., Caradoc-Davies, T. T., Ekkel, S. M., Mazzitelli, B., Whisstock, J. C. & Law, R. H. P., 5 Mar 2019, (Accepted/In press) In : Biochemical Society Transactions. 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Tranexamic acid is an active site inhibitor of urokinase plasminogen activator

Wu, G., Mazzitelli, B. A., Quek, A. J., Veldman, M. J., Conroy, P. J., Caradoc-Davies, T. T., Ooms, L. M., Tuck, K. L., Schoenecker, J. G., Whisstock, J. C. & Law, R. H. P., 12 Mar 2019, In : Blood Advances. 3, 5, p. 729-733 5 p.

Research output: Contribution to journalArticleResearchpeer-review

X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors

Law, R. H. P., Wu, G., Leung, E. W. W., Hidaka, K., Quek, A. J., Caradoc-Davies, T. T., Jeevarajah, D., Conroy, P. J., Kirby, N. M., Norton, R. S., Tsuda, Y. & Whisstock, J. C., 2017, In : Blood Advances. 1, 12, p. 766-771 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Preferential acquisition and activation of plasminogen glycoform II by PAM positive group A streptococcal isolates

De Oliveira, D. M. P., Law, R. H. P., Ly, D., Cook, S. M., Quek, A. J., McArthur, J. D., Whisstock, J. C. & Sanderson-Smith, M. L., 2015, In : Biochemistry. 54, 25, p. 3960 - 3968 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Dimerization is not a determining factor for functional high affinity human plasminogen binding by the group A streptococcal virulence factor PAM and is mediated by specific residues within the PAM a1a2 domain

Bhattacharya, S., Liang, Z., Quek, A. J., Ploplis, V., Law, R. H. P. & Castellino, F. J., 2014, In : Journal of Biological Chemistry. 289, 31, p. 21684 - 21693 10 p.

Research output: Contribution to journalArticleResearchpeer-review