Victorian Heart Institute (VHI)

Projects

Projects per year 2020 2020 2021 2036

• 3 Not started
• 6 Curtailed
• 58 Active
• 183 Finished

Projects per year

Search results

• Finished

  AVANT GUARD - A Prospective Randomized Multicenter Global Study Comparing Pulsed Field Ablation versus Anti-Arrhythmic Drug Therapy as a First Line Treatment for Persistent Atrial Fibrillation RES-24-0000-510X - AVANT GUARD clinical trial

  Healy, S.

  20/08/24 → 12/12/24

  Project: Research

• Open-label, phase 1b, single ascending dose study to evaluate the safety of VERVE-102 administered to patients with heterozygous familial hypercholesterolemia or premature coronary artery disease who require additional lowering of low-density lipoprotein cholesterol

  Nicholls, S.

  12/08/24 → 21/11/24

  Project: Research

• Investigating the acceptability of a co-parenting program for improving lifestyle in pregnant and postpartum women; a qualitative study.

  Lang, S., Moran, L., Hunter, S., Giallo, R. & Feinberg, M.

  1/11/23 → 31/10/24

  Project: Research

• The Association between Cardiovascular Disease and Cancer

  Nerlekar, N., Tan, S. & Nicholls, S.

  9/06/23 → 8/06/24

  Project: Research

• Improving cardiovascular medtech adoption with the Victorian Heart Institute

  Nicholls, S.

  30/04/23 → 28/02/24

  Project: Research

• Characterising the effects of polyphenols on oxidative stress and inflammation in MPO-ANCA vasculitis.

  Houghton, M. & Huang, U.

  1/03/23 → 29/02/24

  Project: Research

• Understanding the mechanisms and therapeutic potential of Fauna compounds in cardiothoracic pathophysiology

  Bubb, K. & Nicholls, S.

  Fauna Bio Incorporated

  1/03/23 → 31/12/24

  Project: Research

• INFLUENCE: INcreasing inFLUEnza immuNisation of Cardiovascular inpatiEnts (INFLUENCE): A multifaceted, multi-level systems approach to increasing adoption

  Nelson, A., Bonner, C., Hickman, J. & Nicholls, S.

  1/01/23 → 31/12/24

  Project: Research

• Manual Pressure Augmentation in Defibrillation of Ventricular Arrhythmias: AUGMENT randomised controlled trial

  Stub, D., Nehme, Z., Smith, K. & Voskoboinik, A.

  1/01/23 → 31/12/24

  Project: Research

• Toxicology assessment of a new AURKA degradation therapy for ADPKD

  Zhao, Y., Cottle, D., Smyth, I. & Baell, J.

  1/09/22 → 1/09/23

  Project: Research

• Obicetrapib and Cardiovascular Outcomes: A Placebo Controlled, Double Blind, Randomized Phase 3 Study to Evaluate the Effect of 10 mg Obicetrapib in Participants with Atherosclerotic Cardiovascular Disease (ASCVD) Who are Not Adequately Controlled Despite Maximally Tolerated Lipid Modifying Therapies

  Nicholls, S.

  1/07/22 → 30/04/23

  Project: Research

• Review of Enrolled Nurses Standards for Practice and Education Pathways - Literature Review

  Morphet, J., Griffiths, D., Innes, K. & Jones, T.

  6/06/22 → 16/08/22

  Project: Research

• Scoping service gaps in Medication Assisted Treatment of Opioid Dependence (MATOD) by evaluating lived experiences of Alcohol and other Drugs Nursing Practitioners (AODNPs) in rural and regional Victoria.

  Patil Vishwanath, T., Shlonsky, A., Buus, N., Nielsen, S., Woode, M. E. & Tyler, J.

  30/05/22 → 30/04/23

  Project: Research

• Pre-hospital point-of-care troponin and paramedic risk assessment in patients withchest pain without ST-elevation: A cluster randomized controlled trial

  Stub, D., Smith, K. & Nehme, Z.

  1/04/22 → 31/03/24

  Project: Research

• Dual-API Drug-Coated Balloon for the treatment of coronary de-novo lesions, ISR or small vessel disease in patients with symptomatic ischemic heart disease

  Nicholls, S.

  Advanced NanoTherapies Inc, Advanced Nanotherapies Australia Pty Ltd

  1/03/22 → 30/06/24

  Project: Research

• The Do stAtins faVourably modify atherosclerotIc plaque in patients with differeNt levels of polygenic Cardiovascular rIsk? (DA VINCI) trial

  Nelson, A.

  National Heart Foundation of Australia

  1/01/22 → 31/12/24

  Project: Research

• Providing digital health support for the Virtual Hospital

  Tan, C., Wang, T., Buntine, W., Tong, E., Bingham, G., Enticott, J., Teede, H. & Bain, C.

  2/12/21 → 2/12/24

  Project: Research

• DHCRC 0158 Enhanced Telehealth Capabilities

  Hoda, R., Bain, C., Li, L., Poon, P. & Franco, M.

  2/12/21 → 30/09/24

  Project: Research

• Ferring Innovation Grant for Racial Equality in Reproductive Medicine and Maternal Health: Inflammasomes, novel regulators of placental inflammation and placental ageing in early-onset preeclampsia: potential biomarkers to identify ethnic disparity in preeclampsia

  Murthi, P., Kumar, B., Samuel, C., Chakraborty, A., Brennecke, S. P. & Karanam, V.

  1/12/21 → 1/11/22

  Project: Research

• Estimating the Illegal Profits from Forced Labour Exploitation

  Woode, M. E.

  15/11/21 → 30/11/22

  Project: Research

• Lead optimisation of novel inhibitors of IRAP for the treatment of fibrosis in diabetes-induced renal and cardiovascular disease

  Gaspari, T., Chai, S., Widdop, R., Thompson, P., Nielsen, K., Perez, S., Dear, A., Yun, B., Pfleger, K. & Barlow, N.

  1/10/21 → 30/11/23

  Project: Research

• Inhibiting cystogenesis in Polycystic Kidney Disease with AURKA PROTACs

  Zhao, Y., Cottle, D., Smyth, I. & Baell, J.

  30/08/21 → 30/08/22

  Project: Research

• Rethinking the Data-driven Discovery of Rare Phenomena

  Boley, M., Buntine, W., Schmidt, D., Kuhlmann, L. & Scheffler, M.

  29/07/21 → 28/07/24

  Project: Research

• Tokopedia : TokoNOW Forecasting Project and Review-based Recommendation Systems development-Tokopedia

  Bergmeir, C., Schmidt, D., Saputra, R., Wilson, C., Taniar, D. & Lee, V.

  27/07/21 → 19/09/22

  Project: Research

• A Phase 1, First-in-Human, Open-Label, Dose-Escalation Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of LM-061 Tablet in Subjects with Advanaced Tumours

  Richardson, G. & Lai, L. H.

  14/07/21 → 31/12/24

  Project: Research

• Noradrenaline Versus Adrenaline in the initial management shock

  Stub, D., Kaye, D., Smith, K. & Bernard, S.

  National Heart Foundation of Australia

  1/07/21 → 31/12/23

  Project: Research

• Victorian Health Innovation Centre

  Nicholls, S. & Zoungas, S.

  28/06/21 → 31/12/22

  Project: Research

• ATBIND: The Australian Traumatic Brain Injury National Data (ATBIND) Project

  O'Reilly, G., Fitzgerald, M., Curtis, K., Kim, Y., Rushworth, N., Mitra, B., Tee, J. W., Hunter, K., Ryder, C., Hendrie, D. V., Fitzgerald, M., Heathcote, K., Udy, A., Wilson, R., Woode, M. E. & Tan, T.

  1/06/21 → 31/05/23

  Project: Research

• A Phase 2 Open-Label, Multicenter Study to Evaluate Efficacy and Safety of ZN-c3 in Adult Women with Recurrent or Persistent Uterine Serous Carcinoma [ZN-c3-004]

  Richardson, G. & Lai, L. H.

  18/05/21 → 31/12/24

  Project: Research

• Custom Designed X-ray Optical Mounts

  Kitchen, M.

  4/05/21 → 31/12/21

  Project: Research

• Lighthouse Handheld Particle Counter

  Alan, T. & Brenker, J.

  4/05/21 → 31/12/21

  Project: Research

• Two DynaMag -5 Magnets

  Coelho Marques, F. & O'Donnell, J.

  4/05/21 → 31/12/21

  Project: Research

• CO2 Incubator

  Andrews, P., Coppel, R., Peleg, A. & Werrett, M.

  4/05/21 → 31/12/21

  Project: Research

• Using dietary therapy to slow the progression of diabetic kidney disease

  Snelson, M., Coughlan, M., Ekinci, E., Baqar, S., Muir, J. & Kellow, N.

  3/05/21 → 31/12/24

  Project: Research

• Unraveling the mechanisms by which chronic hepatitis B infection is associated with an increased risk of gestational diabetes: a prospective cohort study

  Giles, M., Said, J., Krishnaswamy, S. & Palmer, K.

  1/05/21 → 31/07/22

  Project: Research

• Rates and Mechanisms of Azole Resistance in Aspergillus fumigatus Isolates from Australian Patients with Chronic Lung Disease or Post-Lung Transplantation

  Morrissey, O.

  Gilead Sciences (Australia)

  21/04/21 → 31/12/21

  Project: Research

• Genetic, Cellular and Molecular Analysis of Cardiac Septation

  Harvey, R. P., del Monte Nieto, G. & Kelly, R.

  15/04/21 → 31/12/24

  Project: Research

• A randomised, multicentre, double-blind, placebo-controlled, phase III study of first line Carboplatin and Paclitaxel in combination with Durvalumab, followed by maintenance durvalumab with or without Olaparib in patients with newly diagnosed advanced or recurrent endometrial cancer [DUO-E]

  Richardson, G. & Lai, L. H.

  14/04/21 → 31/12/24

  Project: Research

• THOR: The Haemophilia Osteoporosis Registry (THOR): identifying mechanisms bone loss in haemophilia

  Zengin, A., Ebeling, P. & Tran, H.

  1/04/21 → 31/03/22

  Project: Research

• Targeting the cause, not the symptom: a novel approach to treat stiff vessels in high blood pressure

  Qin, C. H. & Wright, K.

  1/04/21 → 31/03/22

  Project: Research

• Familial Hypercholesterolaemia Registry

  Nicholls, S.

  1/04/21 → 1/10/22

  Project: Research

• Implantable devices for vaccine delivery

  Dargaville, T., Adams, M., Meagher, L., McKee, J. & Ruka, D.

  Queensland University of Technology (QUT)

  1/04/21 → 4/10/24

  Project: Research

• Can a nutritional supplement modify the gut microbiota to improve health outcomes in women with preeclampsia?

  Marshall, S. & Gulliver, E.

  1/04/21 → 1/04/22

  Project: Research

• Investigating the protective role of C-type natriuretic peptide in preeclampsia and future cardiovascular risk.

  Bubb, K., Nicholls, S., Hobbs, A., Colafella, K. & Ashton, A.

  National Heart Foundation of Australia

  1/04/21 → 31/03/23

  Project: Research

• High-throughput 3D bioprinting of the tumour microenvironment

  Bray, L., Toh, Y., Risbridger, G., Levett, P., Meagher, L. & Ruka, D.

  1/04/21 → 1/10/24

  Project: Research

• CLEER-HF01-001 early detection of heart failure study

  Nicholls, S.

  22/03/21 → 31/12/21

  Project: Research

• A randomized trial of evolocumab on saphenous vein graft patency following coronary artery bypass surgery ("NEWTON-CABG")

  Nicholls, S. & Skiba, M.

  Unity Health Toronto

  22/03/21 → 8/06/24

  Project: Research

• Internet and telerehabilitation-based management of rotator cuff related shoulder pain: a randomised controlled trial

  Malliaras, P., Haines, T., Skouteris, H., Burstein, F. & Delir Haghighi, P.

  Hospitals Contribution Fund of Australia (trading as HCF Research Foundation)

  20/03/21 → 20/12/23

  Project: Research

• Elucidating the transcriptomic profile of impaired glucose metabolism in diabetic female hearts

  Prakoso, D., Ritchie, R., Nath, A. P., De Blasio, M., Wende, A. & Gregorevic, P.

  18/03/21 → 31/12/21

  Project: Research

• A Phase I, Multi-Center, Open-Label Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of KF-0210 in Patients with Advanced Solid Tumors

  Richardson, G. & Hoon, L. L.

  11/03/21 → 31/12/24

  Project: Research