Research Output

[125I] galanin binding sites in the human nodose ganglion

Sweerts, B., Jarrott, B. & Lawrence, A. J., 2000, In : Life Sciences. p. 2685 - 2690 6 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

[3H] (2S,4R)-4-Methylglutamate: a nolve ligand for the characterization of glutamate transporters

Aprico, K., Beart, P. M., Lawrence, A. J., Crawford, D. & O'Shea, R. D., 2001, In : Journal of Neurochemistry. 77, 5, p. 1218 - 1225 8 p.

Research output: Contribution to journalArticleResearchpeer-review

[3H]adenosine transport in rat dorsal brain stem using a crude synaptosomal preparation

Lawrence, A. J., Castillo-Meléndez, M. & Jarrott, B., 1 Jan 1994, In : Neurochemistry International. 25, 3, p. 221-226 6 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

[3H]Adenosine uptake in brainstem membranes of CD-1 mice lacking the adenosine A2a receptor

Snell, B. J., Day, A. L. C., Ledent, C. & Lawrence, A. J., 2004, In : Life Sciences. 75, 2, p. 225 - 235 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

[3H]N-methylscopolamine dissociation from muscarine receptors affected by low concentrations of allosteric modulators

Christopoulos, A. & Mitchelson, F., 15 Aug 1995, In : European Journal of Pharmacology: Molecular Pharmacology. 290, 3, p. 259-262 4 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

[3H]Zolpidem binding in alcohol - preferring and non-preferring rat brain

Chen, F., Rezvani, A. H., Jarrott, B. & Lawrence, A. J., 1997, In : Neuroscience Letters. p. 103 - 106 4 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

{3H}-(2S,$R)-4-methylglutamate as a marker for the localisation of glutamate transporters

Aprico, K., Beart, P. M., Crawford, D. & O'Shea, R. D., 1999, p. 112 - Post 1-80. 1 p.

Research output: Contribution to conferenceAbstract

2-Aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonists

Ferguson, G. N., Valant, C., Horne, H. J., Figler, H., Flynn, B. L., Linden, J., Chalmers, D. K., Sexton, P., Christopoulos, A. & Scammells, P. J., 2008, In : Journal of Medicinal Chemistry. 51, 19, p. 6165 - 6172 8 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

3- and 6-substituted 2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridines as A1 adenosine receptor allosteric modulators and antagonists

Aurelio, L., Valant, C., Figler, H., Flynn, B. L., Linden, J., Sexton, P., Christopoulos, A. & Scammells, P. J., 2009, In : Bioorganic & Medicinal Chemistry. 17, 20, p. 7353 - 7361 9 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

3-Pyridyl ethers as SPECT radioligands for imaging nicotinic acetylcholine receptors

Henderson, D. J., Eberl, S., Thomson, S., Smith, A., Allan, R. D., Fulham, M. J., Loiacono, R. & Kassiou, M., 2004, In : Applied Radiation and Isotopes. 60, 5, p. 669 - 676 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

3'UTRs of glutathione peroxidases differentially affect selenium-dependent mRNA stability and selenocysteine incorporation efficiency

Muller, C., Wingler, K. & Brigelius-Flohe, R., 2003, In : Biological Chemistry. 384, p. 11 - 18 8 p.

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)

4-phenylpyridin-2-one derivatives: a novel class of positive allosteric modulator of the M1 muscarinic acetylcholine receptor

Mistry, S. N., Jorg, M., Lim, H., Vinh, N. B., Sexton, P. M., Capuano, B., Christopoulos, A., Lane, J. R. & Scammells, P. J., 14 Jan 2016, In : Journal of Medicinal Chemistry. 59, 1, p. 388-409 22 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

5HT transporter sites and 5HT1A and 5HT3 receptors in fawn-hooded rats: a quantitative autoradiography study

Chen, F. & Lawrence, A. J., 2000, In : Alcoholism: Clinical and Experimental Research. p. 1093 - 1102 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6-[N,S-dimethyl-N'-cyanothioureidomethyl]-6,11-dihydro-5H-dibenz[b,e]a zepine hydrochloride (Fran 12): A histamine and 5-hydroxytryptamine antagonist with pressor properties

Law, S. C., Guyett, F. J., King, R. G., Boura, A. L. A., Jackson, W. R. & Hodgson, W. C., 1 Jan 1992, In : Archives Internationales de Pharmacodynamie et de Therapie. 317, p. 67-80 14 p.

Research output: Contribution to journalArticleResearchpeer-review

6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity

Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.

Research output: Contribution to journalArticleResearchpeer-review

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a2-adrenoceptors in the basal ganglia have a role in memory consolidation and reinforcement

Gibbs, M. E. & Summers, R. J., 2003, In : Neuropharmacology. 45, 3, p. 355 - 367 13 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

A-350619

Kemp-Harper, B., 2011, xPharm: The Comprehensive Pharmacology Reference. Elsevier, p. 1 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

A779

Vinh, A., 2011, xPharm: The Comprehensive Pharmacology Reference. Elsevier, p. 1 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

A biochemical and pharmacological examination of Rhamphiophis oxyrhynchus (Rufous beaked snake) venom

Lumsden, N. G., Ventura, S., Dauer, R. & Hodgson, W. C., 2005, In : Toxicon : official journal of the International Society on Toxinology. 45, 2, p. 219 - 231 13 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Accelerated structure-based design of chemically diverse allosteric modulators of a muscarinic G protein-coupled receptor

Miao, Y., Goldfeld, D. A., Moo, E. V., Sexton, P. M., Christopoulos, A., McCammon, J. A. & Valant, C., 20 Sep 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 38, p. E5675-E5684 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
47 Citations (Scopus)

Accumulation of serum lipids by vascular smooth muscle cells involves a macropinocytosis-like uptake pathway and is associated with the downregulation of the ATP-binding cassette transporter A1

Rivera, J., Walduck, A., Thomas, S. R., Glaros, E. N., Hooker, E. U., Guida, E., Sobey, C. G. & Drummond, G. R., 2013, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 386, 12, p. 1081 - 1093 13 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

A cell-based assay for screening of antidotes to, and antivenom against Chironex fleckeri (box jellyfish) venom

Konstantakopoulos, N., Isbister, G. K., Seymour, J. E. & Hodgson, W. C., 2009, In : Journal of Pharmacological and Toxicological Methods. 59, 3, p. 166 - 170 5 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

A central role for venom in predation by Varanus komodoensis (Komodo Dragon) and the extinct giant Varanus ( Megalania) priscus

Fry, B. G., Wroe, S., Teeuwisse, W., van Osch, M. J. P., Moreno, K., Ingle, J., McHenry, C., Ferrara, T., Clausen, P., Scheib, H., Winter, K. L., Greisman, L., Roelants, K., van der Weerd, L., Clemente, C. J., Giannakis, E., Hodgson, W. C., Luz, S., Martelli, P., Krishnasamy, K. & 8 others, Kochva, E., Kwok, H. F., Scanlon, D., Karas, J., Citron, D. M., Goldstein, E. J. C., Mcnaughtan, J. E. & Norman, J. A., 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 22, p. 8969 - 8974 6 p.

Research output: Contribution to journalArticleResearchpeer-review

71 Citations (Scopus)
2 Citations (Scopus)

A comparison of conventional and confocal fluorescence microscopic analysis of single and double labelled tissues

Fong, A. Y., Delaney, P. M., Finkelstein, D. I. & Lawrence, A. J., 1997, p. 155 - 155. 1 p.

Research output: Contribution to conferenceAbstract

A comparison of the development of renal hypertension in male and female rats

Okuniewski, R., Davis, E. A., Jarrott, B. & Widdop, R. E., 1998, In : Clinical Science. p. 445 - 451 7 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

A comparison of the pharmacological activity of venom from the male and female white-tailed spider

Rash, L. D., Davis, E. A., King, R. G. & Hodgson, W. C., 1998, p. 1311 - 1312. 2 p.

Research output: Contribution to conferenceAbstract

A comparison of the pharmacological activity of venom from the male and female white-tailed spider (Lampona cylindrata)

Rash, L. D., Davis, E. A., King, R. G. & Hodgson, W. C., 1997, p. 60 - 60. 1 p.

Research output: Contribution to conferenceAbstract

A constitutive NADPH oxidase-like system containing gp91phox homologs in human keratinocytes

Chamulitrat, W., Stremmel, W., Kawahara, T., Rokutan, K., Fujii, H., Wingler, K., Schmidt, H. & Schmidt, R., 2004, In : Journal of Investigative Dermatology. 122, 4, p. 1000 - 1009 10 p.

Research output: Contribution to journalArticleResearchpeer-review

67 Citations (Scopus)

A critical role for the short intracellular C terminus in receptor activity-modifying protein function

Udawela, M., Christopoulos, G., Morfis, M., Christopoulos, A., Ye, S., Tilakaratne, N. & Sexton, P. M., 2006, In : Molecular Pharmacology. 70, 5, p. 1750 - 1760 11 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Actions of beta3-adrenoceptor agonists in memory consolidation

Gibbs, M. E. & Summers, R. J., 1999, p. 27 - Oral 2-5. 1 p.

Research output: Contribution to conferenceAbstract

Actions of rilmenidine on neurogenic hypertension in BPH/2J genetically hypertensive mice

Jackson, K. L., Palma-Rigo, K., Nguyen-Huu, T-P. & Head, G. A., 2014, In : Journal of Hypertension. 32, 3, p. 575 - 586 12 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Activation and allosteric modulation of a muscarinic acetylcholine receptor

Kruse, A. C., Ring, A. M., Manglik, A., Hu, J., Hu, K., Eitel, K., Hubner, H., Pardon, E., Valant, C., Sexton, P., Christopoulos, A., Felder, C. C., Gmeiner, P., Steyaert, J., Weis, W., Garcia, K. C., Wess, J. & Kobilka, B., 2013, In : Nature. 504, 7478, p. 101 - 106 6 p.

Research output: Contribution to journalArticleResearchpeer-review

522 Citations (Scopus)

Activation of mu opioid receptors sensitizes Transient Receptor Potential Vanilloid Type 1 (TRPV1) via beta-arrestin-2-mediated cross-talk

Rowan, M. P., Bierbower, S. M., Eskander, M. A., Szteyn, K., Por, E. D., Gomez, R., Veldhuis, N. A., Bunnett, N. W. & Jeske, N. A., 2014, In : PLoS ONE. 9, 4, 12 p., e93688.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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28 Citations (Scopus)

Activation of neurokinin NK2 receptors by tackykinin peptides causes contraction of uterus in pregnant women near term

Patak, E. N., Ziccone, S., Story, M. E., Fleming, A. J., Lilley, A. & Pennefather, J. N., 2000, In : Molecular Human Reproduction. p. 549 - 554 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Activation of soluble guanylate cyclase reverses experimental pulmonary hypertension and vascular remodeling

Dumitrascu, R., Weissmann, N., Ghofrani, H. A., Dony, E., Beurerlein, K., Schmidt, H., Stasch, J-P., Gnoth, M. J., Seeger, W., Grimminger, F. & Schermuly, R. T., 2006, In : Circulation. 113, 2, p. 286 - 295 10 p.

Research output: Contribution to journalArticleResearchpeer-review

170 Citations (Scopus)

Activin and NADPH-oxidase in preeclampsia: insights from in vitro and murine studies

Lim, R., Acharya, R., Delpachitra, P., Hobson, S., Sobey, C. G., Drummond, G. R. & Wallace, E. M., 1 Jan 2015, In : American Journal of Obstetrics and Gynecology. 212, 1, p. 86.e1 - 86.e12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Acute and chronic restraint stress: effects on [125I] galanin binding in normotensive and hypertensive rat brain

Sweerts, B., Jarrott, B. & Lawrence, A. J., 2000, In : Brain Research. p. 318 - 329 12 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Acute and chronic restraint stress and the central opioid system in normotensive and hypertensive rats

Sweerts, B., Jarrott, B. & Lawrence, A. J., 1999, p. 48 - Oral 8-3. 1 p.

Research output: Contribution to conferenceAbstract

Acute effect of central administration of urotensin II on baroreflex and blood pressure in conscious normotensive rabbits

Lim, K., Sata, Y., Jackson, K. L., Burke, S. L. & Head, G. A., 23 Feb 2017, In : Frontiers in Physiology. 8, FEB, 9 p., 110.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke

Evans, M. A., Lim, R., Kim, H. A., Chu, H. X., Gardiner-Mann, C. V., Taylor, K. W. E., Chan, C. T., Brait, V. H., Lee, S., Dinh, Q. N., Vinh, A., Phan, T. G., Srikanth, V. K., Ma, H., Arumugam, T. V., Fann, D. Y., Poh, L., Hunt, C. P. J., Pouton, C. W., Haynes, J. M. & 12 others, Selemidis, S., Kwan, W., Teo, L., Bourne, J. A., Neumann, S., Young, S., Gowing, E. K., Drummond, G. R., Clarkson, A. N., Wallace, E. M., Sobey, C. G. & Broughton, B. R. S., 1 Mar 2018, In : Stroke. 49, 3, p. 700-709 10 p.

Research output: Contribution to journalArticleResearchpeer-review

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18 Citations (Scopus)

AdenosineA1 receptor binding hypertensive and normotensive rat brain stem

Krstew, E., Jarrott, B. & Lawrence, A. J., 1998, p. 134 P.80 - 134 P.80. 1 p.

Research output: Contribution to conferenceAbstract

Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function

Fuxe, K., Ferre, S., Canals, M., Torvinen, M., Terasmaa, A., Marcellino, D., Goldberg, S., Staines, W., Jacobsen, K., Lluis, C., Woods, A., Agnati, L. & Franco, R., 2005, In : Journal of Molecular Neuroscience. 26, 2-3, p. 209 - 219 10 p.

Research output: Contribution to journalArticleResearchpeer-review

164 Citations (Scopus)

Adenosine A2A receptor and dopamine D3 receptor interactions: evidence of functional A2A/D3 heteromeric complexes

Torvinen, M., Marcellino, D., Canals, M., Agnati, L., Lluis, C., Franco, R. & Fuxe, K., 2005, In : Molecular Pharmacology. 67, 2, p. 400 - 407 8 p.

Research output: Contribution to journalArticleResearchpeer-review

87 Citations (Scopus)

Adenosine - dopamine receptor interactions in the isolated rat nodose ganglion but not in membranes of dorsal vagal complex

Lawrence, A. J., Krstew, E. & Jarrott, B., 1997, In : Naunyn-Schmiedeberg's Archives of Pharmacology. p. 303 - 308 6 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Adenosine infusion causes transient pulmonary vasoconstriction but sustained systemic vasodilation in conscious sheep

Smolich, J. J., Kemp, B. K. & Chen, H., 1998, p. 125 - 125. 1 p.

Research output: Contribution to conferenceAbstract

Adenylyl cyclase signalling complexes - pharmacological challenges and opportunities

Halls, M. L. & Cooper, D. M. F., Apr 2017, In : Pharmacology and Therapeutics. 172, p. 171-180 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

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22 Citations (Scopus)

Adiponectin receptor signalling in the brain

Thundyil, J., Pavlovski, D., Sobey, C. & Arumugam, T., 2012, In : British Journal of Pharmacology. 165, 2, p. 313 - 327 15 p.

Research output: Contribution to journalArticleResearchpeer-review

138 Citations (Scopus)