Medicine Monash Health

A New Anti-Diabetes Drug as a Novel Therapy for Ovarian Cancer

Plebanski, M., Stephens, A., Oehler, M. & Gorrell, M.

1/01/16 → 31/12/20

Project: Research

A New Anti-Diabetes Drug as a Novel Therapy for Ovarian Cancer

Plebanski, M., Gorrell, M., Oehler, M. & Stephens, A.

National Health & Medical Research Council (NHMRC)

1/01/16 → 31/12/17

Project: Research

A new approach for characterising stromal interactions in prostate cancer and identifying therapeutic targets

Daly, R., Risbridger, G., Taylor, R., Lawrence, M., Wu, J. & Azad, A.

1/01/17 → 31/01/17

Project: Research

A new model of health-care for co-morbid diabetes and chronic kidney disease

Zoungas, S., Teede, H., Kerr, P., Russell, G., Walker, R., Bach, L., Gallagher, M., Fulcher, G., Usherwood, T., Cass, A., Ranasinha, S., Jan, S., Lo, C. & Zimbudzi, E.

Department of Health (Comm)

22/12/17 → 31/12/18

Project: Research

A new set of targets and drugs for improving stroke outcome

Wong, C.

1/01/19 → 31/12/23

Project: Other

An Examination of Motor Functioning in Autism and Asperger's Disorder: An Analysis of Gait & Cortical Brain Activity

Tonge, B., Bradshaw, J., Iansek, R. & Rinehart, N. J.

National Health & Medical Research Council (NHMRC)

2/03/01 → 31/12/03

Project: Research

An Exploration of the Mechanisms Behind Vascular Endothelial Dysfunction and Arterial Wall Stiffness in Human Diabetes

Wigg, S. J.

Pfizer Australia Pty Limited

28/05/01 → …

Project: Research

Animal Respiratory Ventilator (Harvard Apparatus, through Australian distributor SDR Clinical Technology)

White, A.

Collier Charitable Fund

6/01/11 → 31/12/11

Project: Research

An International, Multicenter, Openlabel, Randomized, Phase 3 Study of BLU285 vs Regorafenib in Patients with Locally Advanced Unresectable or Metastatic Gastrointestinal Stromal Tumor (GIST)

Segelov, E.

12/02/19 → 11/02/24

Project: Research

An international, multicentre, noninterventional retrospective study to describe treatment pathways, outcomes, and resource use in patients with classical Hodgkin lymphoma (B-HOLISTIC)

Gilbertson, M.

27/09/18 → 26/09/21

Project: Research

An International, Phase 3, Open-label, Randomized Study of BGB-3111 Compared with Bendamustine plus Rituximab in Patients with Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Opat, S.

1/11/19 → 31/10/24

Project: Research

An investigation into metabolic competition between host and pathogen in infection.

Traven, A., Naderer, T., McConville, M., Beilharz, T. & Hickey, M.

National Health & Medical Research Council (NHMRC)

1/01/19 → 31/12/21

Project: Research

Annual Scientific meeting in Washington DC, USA. The CASS Foundation Limited - Postdoctoral Travel Grants

Yang, Y.

CASS Foundation

Project: Research

An Open-Label, Multicenter, Extension Study for Subjects Who Participated in Prior Guadecitabine Clinical Studies

Shortt, J.

23/04/19 → 22/04/24

Project: Research

An Open-Label, Multicenter, Extension Study To Evaluate The Safety And Efficacy Of Padsevonil As Adjunctive Treatment Of Focal-Onset Seizures In Adult Subjects With Drug-Resistant Epilepsy

Seneviratne, U.

20/06/19 → 19/06/24

Project: Research

An Open-Label, Multicenter, Phase I/Ib Trial Evaluating the Safety and Pharmacokinetics of Escalating Doses of BTCT4465A as a Single Agent and Combined with Atezolizumab in Patients with Relapsed or Refractory B-Cell Non-Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia

Gregory, G.

3/12/18 → 2/12/23

Project: Research

An Open-Label, Multicenter Phase IB Study of the Safety and Efficacy of Atezolizu-L1 Antibody) Administered in Combination with Bevacizumab and/or Other Treatments in Patients with Solid Tumors (G030140) – Arm F Only

Dev, A.

16/11/18 → 15/11/22

Project: Research

An Open Label, Randomized, Two Arm Phase III Study of Nivolumab in Combination with Ipilimumab Versus Extreme Study Revgimen (Cetuximab + Cisplatin/Carboplatin + Fluorouracil) As First Line Therapy in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Alamgeer, M.

12/02/19 → 11/02/24

Project: Research

An open label, single arm pilot study of OncoSil™, administered to study participants with unresectable locally advanced pancreatic adenocarcinoma, given in combination with FOLFIRINOX or gemcitabine+nab-paclitaxel chemotherapies

Harris, M.

4/01/19 → 3/01/24

Project: Research

A novel ionic current contributing to spasm of small blood vessels ID: 334162

Coleman, H., McGrath, B., Parkington, H. & Tare, M.

National Health & Medical Research Council (NHMRC)

1/01/05 → 31/12/07

Project: Research

A novel patient-centred instrument for assessment of SLE

Morand, E.

Arthritis Foundation of Victoria

1/01/12 → 31/12/12

Project: Research

A novel strategy for targeting castrate-resistant prostate cancer

Risbridger, G., Tilley, W. D., Furic, L., Sandhu, S. K., Azad, A., Selth, L. & Lawrence, M.

National Health & Medical Research Council (NHMRC)

1/01/18 → 31/12/21

Project: Research

Antigen-specific regulatory T cells and HLA associations in autoimmune renal disease

Robson, K. J. & Kitching, R.

1/02/18 → 31/01/21

Project: Research

Antigen-specific regulatory T cells and HLA associations in autoimmune renal disease

Robson, K. J. & Kitching, R.

1/02/18 → 31/01/21

Project: Research

A Phase 1, 2-Part, Multicentre, Open-Label, 3 Arm Study to Determine the Effect of Enasidenib (Cc-90007) On the Pharmacokinetics of Single Doses of Caffeine, Dextromethorphan, Flurbiprofen, Midazolam, Omeprazole, Digoxin, Rosuvastatin, And Pioglitazone in Subjects with Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation.

Shortt, J.

16/11/18 → 15/11/23

Project: Research

A Phase 1, First-in-Human, Open-Label Study of the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-67856633, an Inhibitor of MALT1, in Participants with NHL and CLL

Opat, S.

3/06/19 → 2/06/24

Project: Research

A Phase 1, Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of single and multiple doses of ABI-H2158 in Healthy Volunteers; and Multiple-Ascending Dose Pharmacokinetics and pharmacodynamics in Patients with Chronic Hepatitis B Infection

Sievert, W.

20/05/19 → 19/05/24

Project: Research

A Phase 1/2, Open-Label Study to Evaluate the Safety and Antitumor Activity of MEDI0680 (AMP-514) in Combination with MEDI4736 and MEDI0680 Monotherapy in Subjects with Select Advanced Malignancies

Kwan, E.

3/12/18 → 2/12/23

Project: Other

A Phase 1/2, Placebo-Controlled, Randomized, Observer-Blind, Dose-Finding, First-In-Human Study to Describe the Safety, Tolerability, And Immunogenicity of an Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine In Healthy Older Adults

Korman, T.

28/03/19 → 27/03/24

Project: Research

A Phase 1/2, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of VIR-2218

Sievert, W.

12/02/19 → 11/02/24

Project: Research

A Phase 1/2a Single Dose-Escalating Study to Evaluate the Safety, Tolerability and Pharmacokinetic Effects of ARO-HBV in Normal Adult Volunteers and Multiple Escalating Doses Evaluating Safety, Tolerability and Pharmacodynamic Effects in HBV Patients

Sievert, W.

1/02/19 → 31/01/24

Project: Research

A Phase 1/2 Study of Durvalumab and Monalizumab in Adult Subjects with Select Advanced Solid Tumors

Frentzas, S.

1/07/19 → 30/06/24

Project: Research

A Phase 1/Phase 2 Clinical Study to Evaluate the Safety and Efficacy of a Combination of MK-4280 and Pembrolizumab (MK-3475) in Participants with Hematologic Malignancies

Gregory, G.

6/11/19 → 5/11/24

Project: Research

A Phase 1a/1b, Multicenter, Open-label, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK112 in Subjects with Advanced Solid Tumors

Parakh, S.

15/11/19 → 14/11/24

Project: Research

A Phase 1b, Open Label, Multiple Dose, Dose Escalation and Expansion Study to Assess Safety, Tolerability and Antitumor Activities of the Combination of BGB-3111 with BGB-A317 in Subjects with B-Cell Lymphoid Malignancies

Opat, S.

30/04/19 → 29/04/24

Project: Research

COLUMBIA-1: A Phase 1b/2, Open-label, Multicenter Study of Novel Oncology Therapies in Combination with Chemotherapy and Bevacizumab as First-line Therapy in Metastatic Microsatellite-stable Colorectal Cancer

Segelov, E.

26/09/19 → 25/09/24

Project: Research

A Phase 1b/2 study evaluating the safety and efficacy of MPDL3280A in combination with either OBINUTUZUMAB plus BENDAMUSTINE or OBINUTUZUMAB plus chop in patients with follicular lymphoma or diffuse large b-cell lymphoma

Gilbertson, M.

2/08/19 → 1/08/24

Project: Research

A Phase 1b/2 Study of KZR-616 in Patients with Systemic Lupus Erythematosus with and without Nephritis

Hoi, A.

1/11/19 → 31/10/24

Project: Research

A Phase 1b/2 Study to Evaluate the Safety, Pharmacokinetics, and Clinical Activity of Oleclumab (MEDI9447) with or without Durvalumab in Combination with Chemotherapy in Subjects with Metastatic Pancreatic Ductal Adenocarcinoma

Frentzas, S.

29/11/18 → 28/11/23

Project: Research

A Phase 1b Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, And Clinical Activity of EQ001 in Subjects with Moderate-To-Severe Uncontrolled Asthma

Bardin, P.

Project: Research

A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of Oprozomib in Combination with Pomalidomide and Dexamethasone in Subjects with Relapsed or Refractory Multiple Myeloma

Low, M.

7/05/19 → 6/05/24

Project: Research

A Phase 1 First Time in Human Study to Evaluate the Safety, Pharmacokinetics and Immunogenicity of MEDI5083 Alone and in Combination with Durvalumab in Selected Advanced Solid Tumors

Frentzas, S.

25/03/19 → 24/03/24

Project: Research

A Phase 1 Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of HBM4003 Monotherapy in Subjects with Advanced Solid Tumors

Parakh, S.

24/09/19 → 23/09/24

Project: Research

A Phase 1 study of ES414 in Patients with Metastatic Castration Resistant Prostate Cancer

Parakh, S.

1/01/19 → 31/12/23

Project: Research

A Phase 2, Fast Real-time Assessment of Combination Therapies in Immuno-Oncology Study in Participants with Advanced Renal Cell Carcinoma (FRACTION-RCC)

Pook, D.

21/02/19 → 20/02/24

Project: Research

A Phase 2, international, multicenter, randomized, open-label, parallel group study to evaluate the efficacy and safety of CC-486 (Oral Azacitidine) Alone and in combination with the Durvalumab (MEDI14736) in subjects with Myelodysplastic Syndromes who fail to achieve an Objective response to treatment with Azacitidine for Injection of Decitabine

Shortt, J.

12/06/19 → 11/06/24

Project: Research

A phase 2, open label, 2Arm, response rate study of talazoparib in men with DNA repair defects and metastatic castration resistant prostate cancer who previously received taxane based chemotherapy and progressed on at least 1 novel hormonal agent

Kwan, E.

21/04/17 → 28/11/23

Project: Research

A Phase 2, Open-label Trial of guadecitabine (SGI-110) in patients with T-cell Lymphoma

Shortt, J.

3/06/19 → 2/06/24

Project: Research

A Phase 2, single-arm study of bempegaldesleukin (NKTR-214) in combination with nivolumab in cisplatin ineligible, locally advanced or metastatic urothelial cancer patients

Pook, D.

24/06/19 → 23/06/24

Project: Research

QUASAR: A Phase 2b/3, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Protocol to Evaluate the Efficacy and Safety of Guselkumab in Participants with Moderately to Severely Active Ulcerative Colitis

Moore, G.

24/10/19 → 23/10/24

Project: Research