Research Output 1977 2019

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2004

Synthesis and antiviral activity of dimeric capsid-binding inhibitors ofhuman rhinovirus (HRV)

Krippner, G. Y., Chalmers, D. K., Stanislawski, P. C., Tucker, S. P. & Watson, K. G., 2004, In : Australian Journal of Chemistry. 57, 6, p. 553 - 564 12 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Synthesis and antiviral activity of dimeric capsid-binding inhibitors of human rhinovirus (HRV)

Chalmers, D. K., Stanislawski, P. C. & Tucker, S. P., 30 Jun 2004, In : Australian Journal of Chemistry. 57, 6, p. 553-564 12 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Synthesis and serotonergic activity of variously substituted (3-amido) phenylpiperazine derivatives and benzothiopene-4-piperazine derivatives: novel antagonists for the vascular 5-HT1B receptor

Moloney, G. P., Garavelas, A., Martin, G. R., Maxwell, M. & Glen, R. C., 2004, In : European Journal of Medicinal Chemistry. 39, 4, p. 305 - 321 17 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Two monoclonal antibodies to precisely the same epitope of type II collagen select non-crossreactive phage clones by phage display: implications for autoimmunity and molecular mimicry

Xu, Y., Ramsland, P. A., Davies, J. M., Scealy, M., Nandakumar, K. S., Holmdahl, R. & Rowley, M. J., 2004, In : Molecular Immunology. 41, 4, p. 411 - 419 9 p.

Research output: Contribution to journalArticleResearchpeer-review

68 Citations (Scopus)

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat; implications for the binding of cyclic imide inhibitors

El-Kabbani, O., Darmanin, C., Schneider, T. R., Hazemann, I., Ruiz, F., Oka, M., Joachimiak, A., Schulze-Briese, C., Tomizaki, T., Mitschler, A. & Podjarny, A. D., 2004, In : Proteins: Structure, Function, and Bioinformatics. 55, 4, p. 805 - 813 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2003
105 Citations (Scopus)

2-Amino-3-benzoylthiophene Allosteric Enhancers of A1 Adenosine Agonist Binding: New 3, 4- and 5-Modifications

Lutjens, H., Zickgraf, A., Figler, H., Linden, J., Olsson, R. A. & Scammells, P. J., 2003, In : Journal of Medicinal Chemistry. 46, p. 1870 - 1877 8 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-6][1,5]benzodiazepine methanol solvate monohydrate

Capuano, B., Crosby, I. T., Fallon, G. D., Lloyd, E. J., Yuriev, E. & Egan, S., 1 Sep 2003, In : Acta Crystallographica Section E: Structure Reports Online. 59, 9, p. 1367-1369 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

7,8-Didehydro-4,5-epoxy-17-methyl-morphinan-6-yl naphthalene-1-carboxylate

Gathergood, N., Scammells, P. J. & Fallon, G. D., 2003, In : Acta Crystallographica Section E: Structure Reports Online. E59, p. 1918 - 1919 2 p.

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)

A Consensus Neural Network-Based Technique for Discriminating Soluble and Poorly Soluble Compounds

Manallack, D. T., Tehan, B., Gancia, E., Hudson, B. D., Ford, M. G., Livingstone, D. J., Whitley, D. C. & Pitt, W. R., 2003, In : Journal of Chemical Information and Computer Sciences. 43, 2, p. 674 - 679 6 p.

Research output: Contribution to journalArticleResearchpeer-review

65 Citations (Scopus)

A convenient two step protocol for the synthesis of cyclopentenones and indanones, including an asymmetric variant

Kerr, D. J., Metje, C. & Flynn, B. L., 21 Jun 2003, In : Chemical Communications. 9, 12, p. 1380-1381 2 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

A diabetes-related epitope of GAD65: a major diabetes-related conformational epitope on GAD65

Myers, M. A., Fenalti, G., Gray, R. E., Scealy, M., Tong, J. C., El-Kabbani, O. & Rowley, M. J., 2003, In : Annals of the New York Academy of Sciences. 1005, p. 250 - 252 3 p.

Research output: Contribution to journalArticleResearchpeer-review

76 Citations (Scopus)

A glycopeptide in complex with MHC class 1 uses the GaINAc residue as an anchor

Apostolopoulos, V., Yuriev, E., Ramsland, P. A., Halton, J., Osinski, C., Li, W., Plebanski, M., Paulsen, H. & McKenzie, I. F. C., 2003, In : Proceedings of the National Academy of Sciences. 100, 25, p. 15029 - 15034 6 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Allylic halogenation of unsaturated amino acids

Easton, C. J., Edwards, A. J., McNabb, S. B., Merrett, M. C., O'Connell, J. L., Simpson, G. W., Simpson, J. S. & Willis, A. C., 2003, In : Organic and Biomolecular Chemistry. 1, 1, p. 2492 - 2498 7 p.

Research output: Contribution to journalArticleResearchpeer-review

An electron momentum spectroscopy and density functional theory study of the outer valence electronic structure of stella-2, 6-dione

Nixon, KL., Wang, F., Campbell, L., Maddern, T., Winkler, D., Gleiter, R., Loeb, P., Weigold, E. & Brunger, M. J., 2003, In : Journal of Physics B: Atomic, Molecular and Optical Physics. 36, 14, p. 3155-3171 17 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)

An orally bioavailable oxime ether capsid binder with potent activity against human rhinovirus

Watson, K. G., Brown, R. N., Cameron, R., Chalmers, D. K., Hamilton, S., Jin, B., Krippner, G. Y., Luttick, A., McConnell, D. B., Reece, P. A., Ryan, J., Stanislawski, P. C., Tucker, S. P., Wu, W. Y., Barnard, D. L. & Sidwell, R. W., 2003, In : Journal of Medicinal Chemistry. 46, 15, p. 3181 - 3184 4 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

A novel effect of bismuth ions: selective inhibition of the biological activity of glycine-extended gastrin

Pannequin, J., Kovac, S., Tantiongco, J-P., Norton, R., Shulkes, A., Barnham, K. & Baldwin, G., 2003, In : Journal of Biological Chemistry. 279, 4, p. 2453 - 2460 8 p.

Research output: Contribution to journalArticleResearchpeer-review

87 Citations (Scopus)

Composition and diurnal variability of the natural Amazonian aerosol

Graham, B., Guyon, P., Maenhaut, W., Taylor, P. E., Ebert, M., Matthias-Maser, S., Mayol-Bracero, O. L., Godoi, R. H. M., Artaxo, P., Meixner, F. X., Lima Moura, M. A., Eca D'Almeida Rocha, C. H., Van Grieken, R., Glovsky, M. M., Flagan, R. C. & Andreae, M. O., 2003, In : Journal of Geophysical Research. 108, D24, p. AAC5.1 - AAC5.16 16 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Difficult macrocyclizations: New strategies for synthesizing highly strained cyclic tetrapeptides

Meutermans, W. D. F., Bourne, G. T., Golding, S. W., Horton, D. A., Campitelli, M. R., Craik, D. J., Scanlon, M. & Smythe, M. L., 2003, In : Organic Letters. 5, 15, p. 2711 - 2714 4 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Effect of Cyclodextrins on Electrophilic Aromatic Bromination in Aqueous Solution

Dumanski, P., Easton, C. J., Lincoln, S. F. & Simpson, J. S., 2003, In : Australian Journal of Chemistry. 56, 11, p. 1107 - 1111 5 p.

Research output: Contribution to journalArticleResearchpeer-review

59 Citations (Scopus)

Efficient N-Demethylation of opiate alkaloids using a modified nonclassical Polonovski reaction

McCamley, K., Ripper, J. A., Singer, R. D. & Scammells, P. J., 2003, In : Journal of Organic Chemistry. 68, 25, p. 9847 - 9850 4 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Evidence for structurally conserved recognition of the major carbohydrate xenoantigen by natural antibodies

Ramsland, P. A., Farrugia, W., Yuriev, E., Edmundson, A. B. & Sandrin, M. S., 2003, In : Cellular and Molecular Biology. 49, 2, p. 307 - 317 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Expression, purification and preliminary crystallographic analysis of human sorbitol dehydrogenase

Darmanin, C., Iwata, T., Carper, D. A., Sparrow, L. G., Chung, R. P-T. & El-Kabbani, O., 2003, In : Acta Crystallographica Section D: Biological Crystallography. D59, p. 558 - 560 3 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Identification of amino acid residues involved in substrate recognition of L-xylulose reductase by site-directed mutagenesis

Ishikura, S., Isaji, T., Usami, N., Nakagawa, J., El-Kabbani, O. & Hara, A., 2003, In : Chemico-Biological Interactions. 143-144, p. 543 - 550 8 p.

Research output: Contribution to journalArticleResearchpeer-review

In-canopy gradients, composition, and sources of optically active aerosols over the Amazon forest

Guyon, P., Graham, B., Roberts, G. C., Mayol-Bracero, O. L., Maenhaut, W., Artaxo, P. & Andreae, M. O., 2003, In : Journal of Geophysical Research. 108, D18, p. AAC9.1 - AAC9.16 16 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Inter- and intramolecular C-H...interactions in morphine bis(1-naph-thoate)

Gathergood, N., Scammells, P. J. & Fallon, G. D., 2003, In : Acta Crystallographica Section C: Crystal Structure Communications. C59, p. 485 - 487 3 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Investigation of structural requirements of anticancer activity at the paclitaxel/tubulin binding site using CoMFA and CoMSIA

Islam, M. N., Song, Y. & Iskander, M. N., 2003, In : Journal of Molecular Graphics and Modelling. 21, 4, p. 263 - 272 10 p.

Research output: Contribution to journalArticleResearchpeer-review

171 Citations (Scopus)

Iodine -induced reaction cascades for the rapid construction of variously substituted benzothiophenes

Hessian, K. O. & Flynn, B. L., 2003, In : Organic Letters. 5, 23, p. 4377 - 4380 4 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Mapping and molecular modeling of S-adenosyl-L-methionine binding site in N-methyltransferase domains of the multifunctional polypeptide cyclosporin synthetase

Velkov, T. & Lawen, A., 2003, In : Journal of Biological Chemistry. 278, 2, p. 1137 - 1148 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Neural networks in 3D QSAR

Livingstone, D. J. & Manallack, D. T., 2003, In : Qsar & Combinatorial Science. 22, 5, p. 510 - 518 9 p.

Research output: Contribution to journalArticleResearchpeer-review

142 Citations (Scopus)

Organic compounds present in the natural Amazonian aerosol: Characterization by gas chromatography-mass spectrometry

Graham, B., Guyon, P., Taylor, P. E., Artaxo, P., Maenhaut, W., Glovsky, M. M., Flagan, R. C. & Andreae, M. O., 2003, In : Journal of Geophysical Research. 108, D24, p. AAC6.1 - AAC6.13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Physical properties and concentration of aerosol particles over the Amazon tropical forest during background and biomass burning conditions

Guyon, P., Graham, B., Beck, J., Boucher, O., Gerasopoulos, E., Mayol-Bracero, O. L., Roberts, G. C., Artaxo, P. & Andreae, M. O., 2003, In : Atmospheric Chemistry and Physics Discussions. 3, 5, p. 1367 - 1414 48 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Preparation of the 4-hydroxytryptamine scaffold via palladium-catalyzed cyclization: a practical and versatile synthesis of psilocin

Gathergood, N. & Scammells, P. J., 2003, In : Organic Letters. 5, 6, p. 921 - 923 3 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Refractive Index of aerosol particles over the Amazon tropical forest during LBA-EUSTACH 1999

Guyon, P., Boucher, O., Graham, B., Beck, J., Mayol-Bracero, O. L., Roberts, G. C., Maenhaut, W., Artaxo, P. & Andreae, M. O., 2003, In : Journal of Aerosol Science. 34, 7, p. 883 - 907 25 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Role of aerosol size and composition in nucleation scavenging within clouds in a shallow cold front

Levin, Z., Teller, A., Ganor, E., Graham, B., Andreae, M. O., Maenhaut, W., Falkovich, A. H. & Rudich, Y., 2003, In : Journal of Geophysical Research. 108, D22, p. AAC5.1 - AAC5.14 14 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Sedimentation velocity analysis of flexible macromolecules: Self-association and tangling of amyloid fibrils

MacRaild, C. A., Hatters, D. M., Lawrence, L. J. & Howlett, G. J., 1 Apr 2003, In : Biophysical Journal. 84, 4, p. 2562-2569 8 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Selective and potent inhibitors of human 20-hydroxysteroid dehydrogenase (AKR1C1) that metabolizes neurosteroids derived from progesterone

Higaki, Y., Usami, N., Shintani, S., Ishikura, S., El-Kabbani, O. & Hara, A., 2003, In : Chemico-Biological Interactions. 143-144, p. 503 - 513 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Self-micellization of gemfibrozil 1-0- acyl glucuronide in aqueous solution

Shackleford, D. M., Prankerd, R. J., Scanlon, M. J. & Charman, W. N., 2003, In : Pharmaceutical Research. 20, 3, p. 465 - 470 6 p.

Research output: Contribution to journalArticleResearchpeer-review

156 Citations (Scopus)

Steady-state pharmacokinetics of intravenous colistin methanesulphonate in patients with cystic fibrosis

Li, J., Coulthard, K., Milne, R., Nation, R. L., Conway, S., Peckham, U., Etherington, C. & Turnidge, J. D., 2003, In : Journal of Antimicrobial Chemotherapy. 52, p. 987 - 992 6 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Structural determinant for cold inactivation of rodent L-xylulose reductase

Ishikura, S., Usami, N., El-Kabbani, O. & Hara, A., 2003, In : Biochemical and Biophysical Research Communications. 308, 1, p. 68 - 72 5 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Structure-based design of inhibitors of human L-xylulose reductase modelled into the active site of the enzyme

Carbone, V., Darmanin, C., Ishikura, S., Hara, A. & El-Kabbani, O., 2003, In : Bioorganic and Medicinal Chemistry Letters. 13, 8, p. 1469 - 1474 6 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Structure of human aldose reductase holoenzyme in complex with statil: an approach to structure-based inhibitor design of the enzyme

El-Kabbani, O., Ramsland, P. A., Darmanin, C., Chung, R. P-T. & Podjarny, A. D., 2003, In : Proteins: Structure, Function, and Bioinformatics. 50, 2, p. 230 - 238 9 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Study of tropical organic aerosol by thermally assisted alkylation-gas chromatography mass spectrometry

Blazso, M., Janitsek, S., Gelencser, A., Artaxo, P., Graham, B. & Andreae, M. O., 2003, In : Journal of Analytical and Applied Pyrolysis. 68-69, p. 351 - 369 19 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Synthesis and preliminary pharmacological evaluation of 4'-arylalkyl analogues of clozapine. II. *Effect of the nature and length of the linker

Capuano, B., Crosby, I. T., Lloyd, E. J., Podloucka, A. & Taylor, D. A., 2003, In : Australian Journal of Chemistry. 56, p. 875 - 886 12 p.

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)

Systematic of alcohol-induced simple coacervation in aqueous gelatin solutions

Mohanty, B. & Bohidar, H. B., 1 Jul 2003, In : Biomacromolecules. 4, 4, p. 1080-1086 7 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Therapeutic opportunities for antagonism of macrophage migration inhibitory factor

Morand, E. F., Leech, M. T. & Iskander, M. N., 2003, In : Expert Opinion on Therapeutic Patents. 13, 8, p. 1189 - 1212 24 p.

Research output: Contribution to journalArticleResearchpeer-review

103 Citations (Scopus)

The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of crop defense protein alfAFP

Lay, F. T., Schirra, H. J., Scanlon, M. J., Anderson, M. A. & Craik, D. J., 2003, In : Journal of Molecular Biology. 325, p. 175 - 188 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2002
1 Citation (Scopus)

Analysis of agonism by dopamine at the dopaminergic D2 G-protein coupled receptor based on comparative modelling of rhodopsin

Tehan, B. G., Lloyd, E. J., Wong, M. G. & Chalmers, D. K., 2002, In : Molecular Simulation. 28, 10-11, p. 865 - 888 24 p.

Research output: Contribution to journalArticleResearchpeer-review

64 Citations (Scopus)

Antiinflammatory screening of the medicinal plant Gynura procumbens

Iskander, M. N., Song, Y., Coupar, I. M. & Jiratchariyakul, W., 2002, In : Plant Foods for Human Nutrition. 57, 3-4, p. 233 - 244 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Crystallisation of PNMT, the adrenaline-synthesizing enzyme, is critically dependent on a high protein concentration

Begun, J., McLeish, M. J., Caine, J. M., Palant, E., Grunewald, G. L. & Martin, J. L., 2002, In : Acta Crystallographica Section D: Biological Crystallography. D58, Part 2, p. 314 - 315 2 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Crystallization and preliminary crystallographic analysis of human L-xylulose reductase

El-Kabbani, O., Chung, R. P-T., Ishikura, S., Usami, N., Nakagawa, J. & Hara, A., 2002, In : Acta Crystallographica Section D: Biological Crystallography. D58, Part 8, p. 1379 - 1380 2 p.

Research output: Contribution to journalArticleResearchpeer-review