Research Output 1977 2019

Filter
Article
2005
30 Citations (Scopus)

Identification of a unique filamin A binding region within the cytoplasmic domain of glycoprotein Ibalpha

Cranmer, S. L., Pikovski, I., Mangin, P. H., Thompson, P. E., Domagala, T., Frazzetto, M., Salem, H. H. & Jackson, S. P., 2005, In : Biochemical Journal. 387, 3, p. 849 - 858 10 p.

Research output: Contribution to journalArticleResearchpeer-review

220 Citations (Scopus)

Ionic liquids: the neglected issues

Scammells, P. J., Scott, J. L. & Singer, R. D., 2005, In : Australian Journal of Chemistry. 58, 3, p. 155 - 169 15 p.

Research output: Contribution to journalArticleResearchpeer-review

163 Citations (Scopus)

Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: Do Mobius strips exist in nature?

Jennings, C. V., Rosengren, J., Daly, N. L., Plan, M., Stevens, J., Scanlon, M. J., Waine, C., Norman, D. G., Anderson, M. A. & Craik, D. J., 2005, In : Biochemistry. 44, 3, p. 851 - 860 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Palladium-Catalyzed Tandem Alkenyl and Aryl CN Bond Formation: A Cascade N-Annulation Route to 1-Functionalized Indoles

Willis, M. C., Brace, G. N. & Holmes, I. P., 2005, In : Angewandte Chemie - International Edition. 44, 3, p. 403 - 406 4 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Structural and stereochemical revision of isocyanide and isothiocyanate amphilectenes from the Caribbean marine sponge Cribochalina sp.

Ciavatta, M. L., Gavagnin, M., Manzo, E., Puliti, R., Mattia, C. A., Mazzarella, L., Cimino, G., Simpson, J. S. & Garson, M. J., 2005, In : Tetrahedron. 61, 33, p. 8049 - 8053 5 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Structure and substrate-binding mechanism, of human Ap4A hydrolase

Swarbrick, J. D., Buyya, S., Gunawardana, D., Gayler, K. R., McLennan, A. G. & Gooley, P., 2005, In : Journal of Biological Chemistry. 280, p. 8471 - 8481 11 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking

Carbone, V., Ishikura, S., Hara, A. & El-Kabbani, O., 2005, In : Bioorganic & Medicinal Chemistry. 13, 2, p. 301 - 312 12 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity

El-Kabbani, O., Carbone, V., Darmanin, C., Oka, M., Mitschler, A., Podjarny, A. D., Schulze-Briese, C. & Chung, R. P-T., 2005, In : Journal of Medicinal Chemistry. 48, 17, p. 5536 - 5542 7 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Structure of the tetrameric form of human L-xylulose reductase: probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis

El-Kabbani, O., Carbone, V., Darmanin, C., Ishikura, S. & Hara, A., 2005, In : Proteins: Structure, Function, and Bioinformatics. 60, 3, p. 424 - 432 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis of 8-chloro-11-(4-(3-(p-tolyloxy)propyl)piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

Capuano, B., Crosby, I. T., Lim, S. E. K., Lloyd, E. J. & Yuriev, E., 2005, In : Molbank. 12, December, p. M454/1 - M454/2 1 p.

Research output: Contribution to journalArticleOther

Synthesis of Benzyl 2-(4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazin-1-yl)acetate

Camerino, M., Capuano, B., Crosby, I. T. & Lloyd, E. J., 2005, In : Molbank. 12, December, p. M453/1 - M453/2 1 p.

Research output: Contribution to journalArticleOther

41 Citations (Scopus)

The interaction of lipophilic drugs with intestinal fatty acid-binding protein

Velkov, T., Chuang, S., Wielens, J., Sakellaris, H. H., Charman, W. N., Porter, C. J. & Scanlon, M., 2005, In : Journal of Biological Chemistry. 280, 18, p. 17769 - 17776 8 p.

Research output: Contribution to journalArticleResearchpeer-review

101 Citations (Scopus)

The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases

Manallack, D. T., Hughes, R. A. & Thompson, P. E., 2005, In : Journal of Medicinal Chemistry. 48, 10, p. 3449 - 3462 14 p.

Research output: Contribution to journalArticleResearchpeer-review

64 Citations (Scopus)

Three-dimensional structures of carbohydrate determinants of Lewis system antigens: Implications for effective antibody targeting of cancer

Yuriev, E., Farrugia, W., Scott, A. M. & Ramsland, P. A., 2005, In : Immunology and Cell Biology. 83, 6, p. 709 - 717 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

A(1) adenosine receptor agonists: medicinal chemistry and therapeutic potential

Hutchinson, S. A. & Scammells, P. J., 2004, In : Current Pharmaceutical Design. 10, 17, p. 2021 - 2039 19 p.

Research output: Contribution to journalArticleResearchpeer-review

86 Citations (Scopus)

Aldose reductase structures: implications for mechanism and inhibition

El-Kabbani, O., Ruiz, F., Darmanin, C. & Chung, R. P-T., 2004, In : Cellular and Molecular Life Sciences. 61, 7-Aug, p. 750 - 762 13 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)

A molecular understanding of mitoxantrone-DNA adduct formation: Effect of cytosine methylation and flanking sequences

Parker, B. S., Buley, T., Evison, B., Cutts, S. M., Neumann, G. M., Iskander, M. N. & Phillips, D. R., 2004, In : Journal of Biological Chemistry. 279, 118, p. 18814 - 18823 10 p.

Research output: Contribution to journalArticleResearchpeer-review

380 Citations (Scopus)

Biodegradable ionic liquids: Part I. Concept, preliminary targets and evaluation

Gathergood, N., Garcia, M. T. & Scammells, P. J., 2004, In : Green Chemistry. 6, p. 166 - 175 10 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Biosynthetic Pathways to Dichloroimines: Precursor Incorporation Studies on Terpene Metabolites in the Tropical Marine Sponge Stylotella aurantium

Simpson, J. S., Brust, A. & Garson, M. J., 2004, In : Organic and Biomolecular Chemistry. 2, p. 949 - 956 8 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Biosynthetic Pathways to Isocyanides and Isothiocyanates; Precursor Incorporation Studies on Terpene Metabolites in the Tropical Marine Sponges Amphimedon terpenensis and Axinyssa n.sp

Simpson, J. S. & Garson, M. J., 2004, In : Organic and Biomolecular Chemistry. 2, p. 939 - 948 10 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Characterization of two isoforms of mouse 3(17)-hydroxysteriod dehydrogenases of the aldo-keto reductase family

Ishikura, S., Usami, N., Nakajima, S., Kameyama, A., Shiraishi, H., Carbone, V., El-Kabbani, O. & Hara, A., 2004, In : Biological & Pharmaceutical Bulletin. 27, 12, p. 1939 - 1945 7 p.

Research output: Contribution to journalArticleResearchpeer-review

358 Citations (Scopus)

Chemically Catalyzed Asymmetric Cyanohydrin Syntheses

Brunel, J. M. & Holmes, I. P., 2004, In : Angewandte Chemie - International Edition. 43, 21, p. 2752 - 2778 27 p.

Research output: Contribution to journalArticleResearchpeer-review

115 Citations (Scopus)

Comparisons of the HBV and HIV polymerase, and antiviral resistance mutations

Bartholomeusz, A., Tehan, B. G. & Chalmers, D. K., 2004, In : Antiviral Therapy. 9, 2, p. 149 - 160 12 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Crystal structure of human L-xylulose reductase holoenzyme: probing the role of Asn107 with site-directed mutagenesis

El-Kabbani, O., Ishikura, S., Darmanin, C., Carbone, V., Chung, R. P-T., Usami, N. & Hara, A., 2004, In : Proteins: Structure, Function, and Bioinformatics. 55, 3, p. 724 - 732 9 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Cyclodextrin Molecular Reactors

Barr, L., Dumanski, P. G., Easton, C. J., Harper, J. B., Lee, K., Lincoln, S. F., Meyer, A. G. & Simpson, J. S., 2004, In : Journal of Inclusion Phenomena and Macrocyclic Chemistry. 50, 1-2, p. 19 - 24 6 p.

Research output: Contribution to journalArticleResearchpeer-review

891 Citations (Scopus)

Formation of Secondary Organic Aerosols Through Photooxidation of Isoprene

Graham, B., Claeys, M., Vas, G., Wang, W., Vermeylen, R., Pashynska, V., Cafmeyer, J., Guyon, P., Andreae, M. O., Artaxo, P. & Maenhaut, W., 2004, In : Science. 303, p. 1173 - 1176 4 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

From α,β-unsaturated Fischer carbene complexes to highly substituted 3-ethoxycyclopentadienes, masked cyclopentenones

Wu, Y. T., Flynn, B., Schirmer, H., Funke, F., Müller, S., Labahn, T., Nötzel, M. & De Meijere, A., 13 Feb 2004, In : European Journal of Organic Chemistry. 4, p. 724-748 25 p.

Research output: Contribution to journalArticleResearchpeer-review

Getting drugs out the door: benefits of molecular modelling in drug discovery

Manallack, D. T., 2004, In : Chemistry in Australia. 2004, August, p. 14 - 17 4 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

High-resolution structures of human aldose reductase holoenzyme in complex with stereoisomers of the potent inhibitor Fidarestat: stereospecific interaction between the enzyme and a cyclic imide type inhibitor

El-Kabbani, O., Darmanin, C., Oka, M., Schulze-Briese, C., Tomizaki, T., Hazemann, I., Mitschler, A. & Podjarny, A. D., 2004, In : Journal of Medicinal Chemistry. 47, 18, p. 4530 - 4537 8 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Inhibition of Peptidylglycine a-Amidating Monooxygenase by Exploitation of Factors Affecting the Stability and Ease of Formation of Glycyl Radicals

Barratt, B. J., Easton, C. J., Henry, D. J., Li, I. H. W., Radom, L. & Simpson, J. S., 2004, In : Journal of the American Chemical Society. 126, 41, p. 13306 - 13311 6 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Investigation of structure-activity relationships in a series of glibenclamide analogues

Yuriev, E., Kong, D. C. M. & Iskander, M. N., 2004, In : European Journal of Medicinal Chemistry. 39, 10, p. 835 - 847 13 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

Local and regional contributions to the atmospheric aerosol over Tel Aviv, Israel:a case study using elemental, ionic and organic tracers

Graham, B., Falkovich, A. H., Rudich, Y., Maenhaut, W., Guyon, P. & Andreae, M. O., 2004, In : Atmospheric Environment. 38, 11, p. 1593 - 1604 12 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Manganese Dioxide Allylic and Benzylic Oxidation Reactions in Ionic Liquids

Hemeon, I., Barnett, N. W., Gathergood, N., Scammells, P. J. & Singer, R. D., 2004, In : Australian Journal of Chemistry. 57, p. 125 - 128 4 p.

Research output: Contribution to journalArticleResearchpeer-review

107 Citations (Scopus)

Marine Isocyanides and Related Natural Products - Structure, Biosynthesis and Ecology

Garson, M. J. & Simpson, J. S., 2004, In : Natural Product Reports. 21, p. 164 - 179 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Microtubulin binding sites target for developing anticancer agents

Islam, M. N. & Iskander, M. N., 2004, In : Mini reviews in medicinal chemistry. 4, p. 1077 - 1104 28 p.

Research output: Contribution to journalArticleResearchpeer-review

63 Citations (Scopus)

Multicomponent Coupling Approach to (±)-Frondosin B and a Ring-Expanded Analogue

Kerr, D. J., Willis, A. C. & Flynn, B. L., 19 Feb 2004, In : Organic Letters. 6, 4, p. 457-460 4 p.

Research output: Contribution to journalArticleResearchpeer-review

72 Citations (Scopus)

Neural networks as robust tools in drug lead discovery and development

Winkler, D. A., 2004, In : Applied Biochemistry and Biotechnology - Part B Molecular Biotechnology. 27, 2, p. 139-167 29 p.

Research output: Contribution to journalArticleOther

21 Citations (Scopus)

New potent and selective A1 adenosine receptor agonists

Hutchinson, S. A., Baker, S. P., Linden, J. & Scammells, P. J., 2004, In : Bioorganic & Medicinal Chemistry. 12, p. 4877 - 4884 8 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

PDe2 inhibition by the PI3 kinase inhibitor LY294002 and analogues

Abbott, B. M. & Thompson, P., 2004, In : Bioorganic and Medicinal Chemistry Letters. 14, 11, p. 2847 - 2851 5 p.

Research output: Contribution to journalArticleResearchpeer-review

67 Citations (Scopus)

Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen

Macdonald, S. J., Watson, K. G., Cameron, R., Chalmers, D. K., Demaine, D. A., Fenton, R. J., Gower, D., Hamblin, J. M., Hamilton, S., Hart, G. J., Inglis, G. G., Jin, B., Jones, H. T., McConnell, D. B., Mason, A. M., Nguyen, V., Owens, I. J., Parry, N., Reece, P. A., Shanahan, S. E. & 3 others, Smith, D., Wu, W. Y. & Tucker, S. P., 2004, In : Antimicrobial Agents and Chemotherapy. 48, 12, p. 4542 - 4549 8 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Probing the ultra-high resolution structure of aldose reductase with molecular modelling and noncovalent mass spectrometry

Darmanin, C., Chevreux, G., Potier, N., Van Dorsselaer, A., Hazemann, I., Podjarny, A. D. & El-Kabbani, O., 2004, In : Bioorganic & Medicinal Chemistry. 12, 14, p. 3797 - 3806 10 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Quantification of chloride ion impurities in ionic liquids using ICP-MS analysis

McCamley, K., Warner, N. A., Lamoureux, M. M., Scammells, P. J. & Singer, R. D., 2004, In : Green Chemistry. 6, 7, p. 341 - 344 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Returning to Oz to set up home and business: press 2 for self-employment

Manallack, D. T., 2004, In : Australasian Biotechnology. 14, 5, p. 56 - 57 2 p.

Research output: Contribution to journalArticleOther

67 Citations (Scopus)

Scaffold hopping in De Novo design. Ligand generation in the absence of receptor information

Lloyd, D. G., Buenemann, C. L., Todorov, N. P., Manallack, D. T. & Dean, P. M., 2004, In : Journal of Medicinal Chemistry. 47, 3, p. 493 - 496 4 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Small-angle neutron and dynamic light scattering study of gelatin coacervates

Mohanty, B., Aswal, V. K., Goyal, P. S. & Bohidar, H. B., 1 Jan 2004, In : Pramana - Journal of Physics. 63, 2, p. 271-276 6 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Solvent-free preparation of primary imines from 2-hydroxyaryl ketones

Bergman, Y. E., Perlmutter, P. & Thienthong, N., 2004, In : Green Chemistry. 6, 11, p. 539 - 540 2 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Sorbitol Dehydrogenase: Structure, Function and Ligand Design

El-Kabbani, O., Darmanin, C. & Chung, R. P-T., 2004, In : Current Medicinal Chemistry. 11, 4, p. 465 - 476 12 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)

Sources of optically active aerosol particles over the Amazon forest

Guyon, P., Graham, B., Roberts, G. C., Mayol-Bracero, O. L., Maenhaut, W., Artaxo, P. & Andreae, M. O., 2004, In : Atmospheric Environment. 38, 7, p. 1039 - 1051 13 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3

Chow, M. K. M., Mackay, J. P., Whisstock, J. C., Scanlon, M. J. & Bottomley, S. P., 2004, In : Biochemical and Biophysical Research Communications. 322, 3, p. 387 - 394 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis and antiviral activity of dimeric capsid-binding inhibitors ofhuman rhinovirus (HRV)

Krippner, G. Y., Chalmers, D. K., Stanislawski, P. C., Tucker, S. P. & Watson, K. G., 2004, In : Australian Journal of Chemistry. 57, 6, p. 553 - 564 12 p.

Research output: Contribution to journalArticleResearchpeer-review