Research Output 1977 2019

Filter
Article
2007
46 Citations (Scopus)

Selectivity determinants of the aldose and aldehyde reductase inhibitor-binding sites

El-Kabbani, O. & Podjarny, A. D., 2007, In : Cellular and Molecular Life Sciences. 64, 15, p. 1970 - 1978 9 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Structure-activity relationships of adenosines with heterocyclic N6-substituents

Ashton, T. D., Aumann, K. M., Baker, S. P., Schiesser, C. H. & Scammells, P. J., 2007, In : Bioorganic and Medicinal Chemistry Letters. 17, 24, p. 6779 - 6784 6 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Structure of 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) holoenzyme from an orthorhombic crystal form: an insight into the bifunctionality of the enzyme

Dhagat, U., Carbone, V., Chung, R. P-T., Schulze-Briese, C., Endo, S., Hara, A. & El-Kabbani, O., 2007, In : Acta Crystallographica. Section F: Structural Biology Communications. 63, p. 825 - 830 6 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Syntheses, structures and hydrolytic properties of copper(II) complexes of asymmetrically N-functionalised 1,4,7-triazacyclononane ligands

Belousoff, M. J., Battle, A. R., Graham, B. & Spiccia, L., 2007, In : Polyhedron. 26, 2, p. 344 - 355 12 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Synthesis and preliminary pharmacological evaluation of 4'-arylalkyl analogues of clozapine. III. Replacement of the tricyclic nucleus with a bicyclic template

Capuano, B., Crosby, I. T., Lloyd, E. J. & Taylor, D., 2007, In : Australian Journal of Chemistry. 60, 12, p. 928 - 933 6 p.

Research output: Contribution to journalArticleResearchpeer-review

79 Citations (Scopus)

The concise synthesis of chalcone, indanone and indenone analogues of combretastatin A4

Kerr, D. J., Hamel, E., Jung, K. & Flynn, B. L., 2007, In : Bioorganic & Medicinal Chemistry. 15, 9, p. 3290 - 3298 9 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The first aminimide synthesis from benzoyl azide and pyridine

Capuano, B., Crosby, I. T., Lloyd, E. J. & Neve, J. E., 2007, In : Australian Journal of Chemistry. 60, 3, p. 214 - 217 4 p.

Research output: Contribution to journalArticleResearchpeer-review

The pKa Distribution of Drugs: Application to Drug Discovery

Manallack, D. T., 2007, In : Perspectives in Medicinal Chemistry. 1, 1, p. 25 - 38 14 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

The stereochemistry of fatty acid hydroxylation by cytochrome P450BM3

Cryle, M. J., Matovic, N. J. & De Voss, J. J., 1 Jan 2007, In : Tetrahedron Letters. 48, 1, p. 133-136 4 p.

Research output: Contribution to journalArticleResearchpeer-review

52 Citations (Scopus)

Total synthesis of (-)-episilvestrol and (-)-silvestrol

El Sous, M., Khoo, M. L., Holloway, G. A., Owen, D., Scammells, P. J. & Rizzacasa, M. A., 2007, In : Angewandte Chemie - International Edition. 46, 41, p. 7835 - 7838 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

2-(2-Haloalkenyl)-aryl Halides as Substrates for Palladium-Catalysed Tandem CN Bond Formation: Efficient Synthesis of 1-Substituted Indoles

Willis, M. C., Brace, G. N., Findlay, T. J. K. & Holmes, I. P., 2006, In : Advanced Synthesis and Catalysis. 348, 7-8, p. 851 - 856 6 p.

Research output: Contribution to journalArticleResearchpeer-review

73 Citations (Scopus)

2-Aminothiophene-3-carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers

Nikolakopoulos, G., Figler, H., Linden, J. & Scammells, P. J., 2006, In : Bioorganic & Medicinal Chemistry. 14, 7, p. 2358 - 2365 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

5,5'-(Piperazine-1,4-diyl)bis(8-chloropyrido-[2,3-b][1,5]benzoxazepine)

Capuano, B., Crosby, I. T., Forsyth, C. M., Lloyd, E. J., Vom, A. & Yuriev, E., 2006, In : Acta Crystallographica Section E: Structure Reports Online. 62, 12, p. O5434 - O5436 3 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity

Abbott, B. & Thompson, P. E., 2006, In : Bioorganic and Medicinal Chemistry Letters. 16, 4, p. 969 - 973 5 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

An expedient synthesis of N6-substituted-5'-modified adenosines

Ashton, T. D. & Scammells, P. J., 2006, In : Bioorganic and Medicinal Chemistry Letters. 16, 17, p. 4564 - 4566 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

A practical method for phosphorylation of combretastatin A-4 with phosphorus oxychloride

Gurmit, G. S., Grobelny, D. & Flynn, B. L., 2006, In : Organic Preparations and Procedures International. 38, 6, p. 604 - 608 5 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Aromatic chlorination of omega-phenylalkylamines and omega-phenylalkylamides in carbon tetrachloride and alpha,alpha,alpha-trifluorotoluene

Simpson, J. S., Dumanski, P., O'Connell, J. L., Simpson, G. & Easton, C. J., 2006, In : Organic and Biomolecular Chemistry. 4, 14, p. 2716 - 2723 8 p.

Research output: Contribution to journalArticleResearchpeer-review

216 Citations (Scopus)

Biodegradable ionic liquids: Part III. The first readily biodegradable ionic liquids

Gathergood, N., Scammells, P. J. & Garcia, M. T., 2006, In : Green Chemistry. 8, 2, p. 156 - 160 5 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Characterisation of an autoreactive conformational epitope on GAD65 recognised by the human monoclonal antibody b78 using a combination of phage display, in vitro mutagenesis and molecular modelling

O'Connor, K. H., Banga, J. P., Darmanin, C., El-Kabbani, O., Mackay, I. R. & Rowley, M. J., 2006, In : Journal of Autoimmunity. 26, 3, p. 172 - 181 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Computational Methods for Generating Robust, Predictive Models of Biological Properties

Winkler, D. A., 2006, In : Touch Briefings. 4, 1, p. 47-48 2 p.

Research output: Contribution to journalArticleOther

4 Citations (Scopus)

Discovery of potential sorbitol dehydrogenase inhibitors from virtual screening

Darmanin, C., Iwata, T., Carper, D. A. & El-Kabbani, O., 2006, In : Medicinal Chemistry. 2, 3, p. 239 - 242 4 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family

Matsumoto, K., Endo, S., Ishikura, S., Matsunaga, T., Tajima, K., El-Kabbani, O. & Hara, A., 2006, In : Biological & Pharmaceutical Bulletin. 29, 3, p. 539 - 542 4 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Further investigation of the N-demethylation of tertiary amine alkaloids using the non-classical Polonovski reaction

Thavaneswaran, S. & Scammells, P. J., 2006, In : Bioorganic and Medicinal Chemistry Letters. 16, 11, p. 2868 - 2871 4 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Macrocyclic diarylheptanoids from Garuga pinnata

Ara, K., Rahman, A. H. M. M., Hasan, C. M., Iskander, M. N., Asakawa, Y., Quang, D. M. & Rashid, M. A., 2006, In : Phytochemistry. 67, 24, p. 2659 - 2662 4 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Molecular cloning of a novel type of rat cytoplasmic 17beta-hydroxysteroid dehydrogenase distinct from the type 5 isozyme

Ishikura, S., Matsumoto, K., Sanai, M., Horie, K., Matsunaga, T., Tajima, K., El-Kabbani, O. & Hara, A., 2006, In : Journal of Biochemistry. 139, 6, p. 1053 - 1063 11 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Molecular dynamics simulations of spontaneous bile salt aggregation

Warren, D. B., Chalmers, D. K., Hutchison, K., Dang, W. & Pouton, C. W., 2006, In : Colloids and Surfaces A: Physicochemical and Engineering Aspects. 280, 1-3, p. 182 - 193 12 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

N-demethylation of Alkaloids

Thavaneswaran, S., McCamley, K. & Scammells, P. J., 2006, In : Natural Product Communications. 1, 10, p. 885 - 897 13 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Optimization of a pharmacophore model for 5-HT4 agonists using CoMFA and receptor based alignment

Iskander, M. N., Leung, L. M., Buley, T., Ayad, F., Di Iulio, J. L., Tan, Y. Y. & Coupar, I. M., 2006, In : European Journal of Medicinal Chemistry. 41, 1, p. 16 - 26 11 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Oxalato-bridged dinuclear copper(II) complexes of N-alkylated derivatives of 1,4,7-triazacyclononane: synthesis, X-ray crystal structures and magnetic properties

Belousoff, M. J., Graham, B., Moubaraki, B., Murray, K. S. & Spiccia, L., 2006, In : European Journal of Inorganic Chemistry. 23, p. 4872 - 4878 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Role of Tyr356(7.43) and Ser190(4.57) in antagonist binding in the rat beta1-adrenergic receptor

Rezzmann-Vitti, L. A., Nero, T. L., Jackman, G. P., Machida, C. A., Duke, B. J., Louis, W. J. & Louis, S. N. S., 2006, In : Journal of Medicinal Chemistry. 49, 12, p. 3467 - 3477 11 p.

Research output: Contribution to journalArticleResearchpeer-review

106 Citations (Scopus)

Selective endo and exo iodocyclizations in the synthesis of Quinolines and Indoles

Hessian, K. O. & Flynn, B. L., 2006, In : Organic Letters. 8, 2, p. 243 - 246 4 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Solid-Phase Synthesis of 2,3-Disubstituted Benzo[b]thiophenes and Benzo[b]selenophenes

Bui, C. T. & Flynn, B. L., 2006, In : Journal of Combinatorial Chemistry. 8, 2, p. 163 - 167 5 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Stereochenols A and B, two quinones from Stereospermum chelonoides

Haque, M. R., Rahman, K. M., Iskander, M. N., Hasan, C. M. & Rashid, M. A., 2006, In : Phytochemistry. 67, 24, p. 2663 - 2665 3 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Substrate specificity of a mouse aldo-keto reductase (AKR1C12)

Endo, S., Matsumoto, K., Matsunaga, T., Ishikura, S., Tajima, K., El-Kabbani, O. & Hara, A., 2006, In : Biological & Pharmaceutical Bulletin. 29, 12, p. 2488 - 2492 5 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

The binding interaction of synthetic ozonide antimalarials with natural and modified beta-cyclodextrins

Perry, C. S., Charman, S. A., Prankerd, R. J., Chiu, F. C. K., Scanlon, M. J., Chalmers, D. K. & Charman, W. N., 2006, In : Journal of Pharmaceutical Sciences. 95, 1, p. 146 - 158 13 p.

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)

The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling

Gibbs, G. M., Scanlon, M. J., Swarbrick, J. D., Curtis, S., Gallant, E., Dulhunty, A. F. & O'Bryan, M. K., 2006, In : Journal of Biological Chemistry. 281, 7, p. 4156 - 4163 8 p.

Research output: Contribution to journalArticleResearchpeer-review

135 Citations (Scopus)

The major human and mouse granzymes are structurally and functionally divergent

Kaiserman, D., Bird, C. H., Sun, J., Matthews, A. Y., Ung, K. S., Whisstock, J. C., Thompson, P. E., Trapani, J. A. & Bird, P. I., 2006, In : Journal of Cell Biology. 175, 4, p. 619 - 630 12 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Unsaturated N-acetyl-D-glucosaminuronic acid glycosides as inhibitors of influenza virus sialidase

Mann, M. C., Islam, T., Dyason, J. C., Florio, P., Trower, C. J., Thomson, R. J. & Von Itzstein, M., 2006, In : Glycoconjugate Journal. 23, 1-2, p. 127 - 133 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
50 Citations (Scopus)

2-Ethoxybenzoxazole as a bioisosteric replacement of an ethyl benzoate group in a human rhinovirus (HRV) capsid binder

Brown, R. N., Cameron, R., Chalmers, D. K., Hamilton, S., Luttick, A., Krippner, G. Y., McConnell, D. B., Nearn, R., Stanislawski, P. C., Tucker, S. P. & Wattson, K. G., 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, p. 2051 - 2055 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

4-chloro-N-[4-(8-chloro-5H-dibenzo[6,e][1,4]-diazepin-11-yl) -1-methylpiperazinio]benzamidate dichloromethane solvate

Capuano, B., Crosby, I. T., Egan, S., Fallon, G. D., Lloyd, E. J. & Neve, J. E., 2005, In : Acta Crystallographica Section E: Structure Reports Online. 61, Part 1, p. o20 - o22 3 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

An improved method for the purification of rat liver-type fatty acid binding protein from Escherichia coli

Velkov, T., Chuang, S., Prankerd, R. J., Sakellaris, H. H., Porter, C. J. H. & Scanlon, M. J., 2005, In : Protein Expression and Purification. 44, 1, p. 23 - 31 9 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

An improved synthesis of 5'-fluoro-5'-deoxyadenosines

Scammells, P. J. & Ashton, T. D., 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, p. 3361 - 3363 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

A reversed-phase HPLC-based method for the assay of cyclic nucleotide phosphodiesterase activity

Abbott, B. M. & Thompson, P. E., 2005, In : Analytical Biochemistry. 339, 1, p. 185 - 187 3 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

A three-dimensional model of the human immunodeficiency virus type 1 integration complex

Wielens, J., Crosby, I. T. & Chalmers, D. K., 2005, In : Journal of Computer-Aided Molecular Design. 19, 5, p. 301 - 317 17 p.

Research output: Contribution to journalArticleResearchpeer-review

439 Citations (Scopus)

Biodegradable ionic liquids Part II. Effect of the anion and toxicology

Garcia, M. T., Gathergood, N. & Scammells, P. J., 2005, In : Green Chemistry. 7, p. 9 - 14 6 p.

Research output: Contribution to journalArticleResearchpeer-review

100 Citations (Scopus)

Characterization of oxygenated derivatives of isoprene related to 2-methyltetrols in Amazonian aerosols using trimethylsilylation and gas chromatography/ion trap mass spectrometry

Wang, W., Kourtchev, I., Graham, B., Cafmeyer, J., Maenhaut, W. & Claeys, M., 2005, In : Rapid Communications in Mass Spectrometry. 19, 10, p. 1343 - 1351 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)a-hydroxysteroid dehydrogenase

El-Kabbani, O., Ishikura, S., Wagner, A., Schulze-Briese, C. & Hara, A., 2005, In : Acta Crystallographica. Section F: Structural Biology Communications. F61, Part 6, p. 688 - 690 3 p.

Research output: Contribution to journalArticleOther

28 Citations (Scopus)

Demonstration of co-polymerization in melamine-urea-formaldehyde reactions using 15N NMR correlation spectroscopy

Philbrook, A., Blake, C. J., Dunlop, N. F., Easton, C. J., Keniry, M. A. & Simpson, J. S., 2005, In : Polymer. 46, 7, p. 2153 - 2156 4 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Determination of psilocin and psilocybin using flow injection analysis with acidic potassium permanganate and tris(2,2'-bipyridyl)ruthenium(II) chemiluminescence detection respectively

Anastos, N., Barnett, N. W., Lewis, S. W., Gathergood, N., Scammells, P. J. & Sims, D. N., 2005, In : Talanta. 67, p. 354 - 359 6 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Efficient palladium-catalysed enamide synthesis from enol triflates and enol tosylates

Willis, M. C., Brace, G. N. & Holmes, I. P., 2005, In : Synthesis-Stuttgart. 19, p. 3229 - 3234 6 p.

Research output: Contribution to journalArticleResearchpeer-review