Research Output 1983 2019

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2019

Antibiotic resistance and host immune evasion in Staphylococcus aureus mediated by a metabolic adaptation

Jiang, J-H., Bhuiyan, M. S., Shen, H-H., Cameron, D. R., Rupasinghe, T. W. T., Wu, C. M., Le Brun, A. P., Kostoulias, X., Domene, C., Fulcher, A. J., McConville, M. J., Howden, B. P., Lieschke, G. J. & Peleg, A. Y., 26 Feb 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3722-3727 6 p.

Research output: Contribution to journalArticleResearchpeer-review

A population-based analysis of invasive fungal disease in haematology-oncology patients using data linkage of state-wide registries and administrative databases: 2005 - 2016

Valentine, J. C., Morrissey, C. O., Tacey, M. A., Liew, D., Patil, S., Peleg, A. Y. & Ananda-Rajah, M. R., 21 Mar 2019, In : BMC Infectious Diseases. 19, 1, 11 p., 274.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Association between plasma antibody responses and risk for Cryptococcus-associated immune reconstitution inflammatory syndrome

Yoon, H. A., Nakouzi, A., Chang, C. C., Kuniholm, M., Carreño, L. J., Wang, T., Ndung'u, T., Lewin, S. R., French, M. A. & Pirofski, L-A., 1 Feb 2019, In : Journal of Infectious Diseases. 219, 3, p. 420-428 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Association of HIV Preexposure Prophylaxis With Incidence of Sexually Transmitted Infections Among Individuals at High Risk of HIV Infection

Traeger, M. W., Cornelisse, V. J., Asselin, J., Price, B., Roth, N. J., Willcox, J., Tee, B. K., Fairley, C. K., Chang, C. C., Armishaw, J., Vujovic, O., Penn, M., Cundill, P., Forgan-Smith, G., Gall, J., Pickett, C., Lal, L., Mak, A., Spelman, T. D., Nguyen, L. & 12 othersMurphy, D. A., Ryan, K. E., El-Hayek, C., West, M., Ruth, S., Batrouney, C., Lockwood, J. T., Hoy, J. F., Hellard, M. E., Stoové, M. A., Wright, E. J. & PrEPX study team, 9 Apr 2019, In : JAMA. 321, 14, p. 1380-1390 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Cardiovascular disease and diabetes in HIV-positive and HIV-negative gay and bisexual men over the age of 55 years in Australia: insights from the Australian Positive & Peers Longevity Evaluation Study

Puhr, R., Petoumenos, K., Huang, R., Templeton, D. J., Woolley, I., Bloch, M., Russell, D., Law, M. G. & Cooper, D. A., 1 Feb 2019, In : HIV Medicine. 20, 2, p. 121-130 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia

Rees, V. E., Deveson Lucas, D. S., López-Causapé, C., Huang, Y., Kotsimbos, T., Bulitta, J. B., Rees, M. C., Barugahare, A., Peleg, A. Y., Nation, R. L., Oliver, A., Boyce, J. D. & Landersdorfer, C. B., 1 Apr 2019, In : Antimicrobial Agents and Chemotherapy. 63, 4, 11 p., e02538-18.

Research output: Contribution to journalArticleResearchpeer-review

Community-based, point-of-care hepatitis C testing: perspectives and preferences of people who inject drugs

Latham, N. H., Pedrana, A., Doyle, J. S., Howell, J., Williams, B., Higgs, P., Thompson, A. J. & Hellard, M. E., 1 Jan 2019, (Accepted/In press) In : Journal of Viral Hepatitis. 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome Is Associated With Dysregulation of IL-7/IL-7 Receptor Signaling Pathway in T Cells and Monocyte Activation

Akilimali, N. A., Muema, D. M., Specht, C., Chang, C. C., Moosa, M. Y. S., Levitz, S. M., Lewin, S. R., French, M. A. & Ndungʼu, T., 15 Apr 2019, In : JAIDS. 80, 5, p. 596-604 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae

Wyres, K. L., Wick, R. R., Judd, L. M., Froumine, R., Tokolyi, A., Gorrie, C. L., Lam, M. M. C., Duchêne, S., Jenney, A. & Holt, K. E., 1 Apr 2019, In : PLoS Genetics. 15, 4, 25 p., e1008114.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Evidence for a new paradigm of gonorrhoea transmission: Cross-sectional analysis of Neisseria gonorrhoeae infections by anatomical site in both partners in 60 male couples

Cornelisse, V. J., Williamson, D., Zhang, L., Chen, M. Y., Bradshaw, C., Hocking, J. S., Hoy, J., Howden, B. P., Chow, E. P. F. & Fairley, C. K., Apr 2019, (Accepted/In press) In : Sexually Transmitted Infections. 6 p., 053803.

Research output: Contribution to journalArticleResearchpeer-review

Evolution of daptomycin resistance in coagulase-negative staphylococci involves mutations of the essential two-component regulator WALKR

Jiang, J-H., Dexter, C., Cameron, D. R., Monk, I. R., Baines, S. L., Abbott, I. J., Spelman, D. W., Kostoulias, X., Nethercott, C., Howden, B. P. & Peleg, A. Y., 1 Mar 2019, In : Antimicrobial Agents and Chemotherapy. 63, 3, 10 p., e01926-18.

Research output: Contribution to journalArticleResearchpeer-review

Hepatitis B management during immunosuppression for haematological and solid organ malignancies: an Australian consensus statement

Doyle, J., Raggatt, M., Slavin, M., McLachlan, S. A., Strasser, S. I., Sasadeusz, J. J., Howell, J., Hajkowicz, K., Nandurkar, H., Johnston, A., Bak, N. & Thompson, A. J., 3 Jun 2019, In : Medical Journal of Australia. 210, 10, p. 462-468 7 p.

Research output: Contribution to journalArticleOtherpeer-review

Identification of 5-Substituted 2-Acylaminothiazoles That Activate Tat-Mediated Transcription in HIV-1 Latency Models

Nguyen, W., Jacobson, J., Jarman, K. E., Jousset Sabroux, H., Harty, L., McMahon, J., Lewin, S. R., Purcell, D. F. & Sleebs, B. E., 23 May 2019, In : Journal of Medicinal Chemistry. 62, 10, p. 5148-5175 28 p.

Research output: Contribution to journalArticleResearchpeer-review

Identification of Novel Acinetobacter baumannii Host Fatty Acid Stress Adaptation Strategies

Jiang, J. H., Hassan, K. A., Begg, S. L., Rupasinghe, T. W. T., Naidu, V., Pederick, V. G., Khorvash, M., Whittall, J. J., Paton, J. C., Paulsen, I. T., McDevitt, C. A., Peleg, A. Y. & Eijkelkamp, B. A., 5 Feb 2019, In : mBio. 10, 1, 6 p., e02056-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Impaired STAT3-Dependent Upregulation of IL2Rα in B Cells of a Patient With a STAT1 Gain-of-Function Mutation

van Zelm, M. C., Bosco, J. J., Aui, P. M., De Jong, S., Hore-Lacy, F., O'Hehir, R. E., Stirling, R. G. & Cameron, P. U., 1 Jan 2019, In : Frontiers in Immunology. 10, 7 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access

Improving hepatitis C direct-acting antiviral access and uptake: A role for patient-reported outcomes and lived experience

Goutzamanis, S., Doyle, J., Higgs, P. & Hellard, M., 1 Feb 2019, In : Journal of Viral Hepatitis. 26, 2, p. 218-223 6 p.

Research output: Contribution to journalArticleOtherpeer-review

Incidence, Clearance, and Persistence of Anal Human Papillomavirus in Men Who Have Sex With Men Living With Human Immunodeficiency Virus: Implications for Human Papillomavirus Vaccination

Ong, J. J., Walker, S., Grulich, A., Hoy, J., Read, T. R. H., Bradshaw, C., Chen, M., Garland, S. M., Cornall, A., Hillman, R., Templeton, D. J., Hocking, J., Eu, B., Tee, B. K., Chow, E. P. F. & Fairley, C. K., 1 Apr 2019, In : Sexually Transmitted Diseases. 46, 4, p. 229-233 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Outcomes of treatment for hepatitis C in prisoners using a nurse-led, statewide model of care

Papaluca, T., McDonald, L., Craigie, A., Gibson, A., Desmond, P., Wong, D., Winter, R., Scott, N., Howell, J., Doyle, J., Pedrana, A., Lloyd, A., Stoove, M., Hellard, M., Iser, D. & Thompson, A., 1 May 2019, In : Journal of Hepatology. 70, 5, p. 839-846 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Performance of neural network basecalling tools for Oxford Nanopore sequencing

Wick, R. R., Judd, L. M. & Holt, K. E., 24 Jun 2019, In : Genome Biology. 20, 1, 10 p., 129.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Point-of-care hepatitis C testing from needle and syringe programs: An Australian feasibility study

Williams, B., Howell, J., Doyle, J., Thompson, A. J., Draper, B., Layton, C., Latham, N., Bramwell, F., Membrey, D., Mcpherson, M., Roney, J., Stoové, M., Hellard, M. E. & Pedrana, A., 22 May 2019, (Accepted/In press) In : International Journal of Drug Policy. 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Population Pharmacokinetics and Pharmacodynamics of Disulfiram on Inducing Latent HIV-1 Transcription in a Phase IIb Trial

Lee, S. A., Elliott, J. H., McMahon, J., Hartogenesis, W., Bumpus, N. N., Lifson, J. D., Gorelick, R. J., Bacchetti, P., Deeks, S. G., Lewin, S. R. & Savic, R. M., 1 Mar 2019, In : Clinical Pharmacology and Therapeutics. 105, 3, p. 692-702 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Quantitative evaluation of an integrated nurse model of care providing hepatitis C treatment to people attending homeless services in Melbourne, Australia

Harney, B. L., Whitton, B., Lim, C., Paige, E., McDonald, B., Nolan, S., Pemberton, D., Hellard, M. E. & Doyle, J. S., 10 Apr 2019, (Accepted/In press) In : International Journal of Drug Policy. 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Routine versus Targeted Viral Load Strategy among Patients Starting Antiretroviral in Hanoi, Vietnam

Pollack, T. M., Duong, H. T., Pham, T. T., Nguyen, T. D., Libman, H., Ngo, L., McMahon, J. H., Elliott, J. H., Do, C. D. & Colby, D. J., 1 Mar 2019, In : Journal of the International AIDS Society. 22, 3, 9 p., e25258.

Research output: Contribution to journalArticleResearchpeer-review

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Spectrum of illness among returned Australian travellers from Bali, Indonesia: a 5-year retrospective observational study

Sohail, A., McGuinness, S. L., Lightowler, R., Leder, K., Jomon, B., Bain, C. A. & Peleg, A. Y., 1 Jan 2019, In : Internal Medicine Journal. 49, 1, p. 34-40 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Staying hepatitis C negative: A systematic review and meta-analysis of cure and reinfection in people who inject drugs

Latham, N. H., Doyle, J. S., Palmer, A. Y., Vanhommerig, J. W., Agius, P., Goutzamanis, S., Li, Z., Pedrana, A., Gottfredsson, M., Bouscaillou, J., Luhmann, N., Mazhnaya, A., Altice, F. L., Saeed, S., Klein, M., Falade-Nwulia, O. O., Aspinall, E., Hutchinson, S., Hellard, M. E. & Sacks-Davis, R., 24 May 2019, (Accepted/In press) In : Liver International. 17 p.

Research output: Contribution to journalArticleResearchpeer-review

The safety of inactivated influenza vaccines in pregnancy for birth outcomes: a systematic review

Giles, M. L., Krishnaswamy, S., Macartney, K. & Cheng, A., 26 Mar 2019, In : Human Vaccines & Immunotherapeutics. 15, 3, p. 687-699 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Treatment access is only the first step to hepatitis C elimination: experience of universal anti-viral treatment access in Australia

Doyle, J. S., Scott, N., Sacks-Davis, R., Pedrana, A. E., Thompson, A. J., Hellard, M. & the Eliminate Hepatitis C Partnership, 25 Mar 2019, (Accepted/In press) In : Alimentary Pharmacology and Therapeutics.

Research output: Contribution to journalArticleResearchpeer-review

“Cold and lonely”: emergency presentations of patients with hypothermia to a large Australian health network

Forcey, D., Fitzgerald, M., Kuczynska-Burggraf, M., Nagalingham, V. & Ananda-Rajah, M., 9 Apr 2019, (Accepted/In press) In : Internal Medicine Journal. 31 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

Achieving 90-90-90 Human Immunodeficiency Virus (HIV) Targets Will Not Be Enough to Achieve the HIV Incidence Reduction Target in Australia

Scott, N., Stoové, M., Kelly, S. L., Wilson, D. P. & Hellard, M. E., 1 Apr 2018, In : Clinical Infectious Diseases. 66, 7, p. 1019-1026 8 p.

Research output: Contribution to journalArticleResearchpeer-review

A comprehensive evaluation of Xpert MTB/RIF assay with bronchoalveolar lavage fluid as a single test or combined with conventional assays for diagnosis of pulmonary tuberculosis in China: A two-center prospective study

Pan, X., Yang, S., Deighton, M. A., Qu, Y., Hong, L. & Su, F., 1 Mar 2018, In : Frontiers in Microbiology. 9, MAR, 10 p., 444.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Antibiotic allergy testing improves antibiotic appropriateness in patients with cancer

Trubiano, J. A., Grayson, M. L., Phillips, E. J., Stewardson, A. J., Thursky, K. A. & Slavin, M. A., 1 Nov 2018, In : Journal of Antimicrobial Chemotherapy. 73, 11, p. 3209-3211 3 p.

Research output: Contribution to journalArticleOtherpeer-review

Antibiotic exposure and interpersonal variance mask the effect of ivacaftor on respiratory microbiota composition

Peleg, A. Y., Choo, J. M., Langan, K. M., Edgeworth, D., Keating, D., Wilson, J., Rogers, G. B. & Kotsimbos, T., 1 Jan 2018, In : Journal of Cystic Fibrosis. 17, 1, p. 50-56 7 p.

Research output: Contribution to journalArticleResearchpeer-review

A registry for patients with asplenia/hyposplenism reduces the risk of infections with encapsulated organisms

Arnott, A., Jones, P., Franklin, L. J., Spelman, D., Leder, K. & Cheng, A. C., 15 Aug 2018, In : Clinical Infectious Diseases. 67, 4, p. 557-561 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Beliefs in Antiretroviral Treatment and Self-Efficacy in HIV Management are Associated with Distinctive HIV Treatment Trajectories

Mao, L., de Wit, J., Adam, P., Post, J., Slavin, S., Cogle, A., Wright, E. & Kidd, M., Mar 2018, In : AIDS and Behavior. 22, 3, p. 887-895 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Changes in plasma lipidome following initiation of antiretroviral therapy

Trevillyan, J. M., Wong, G., Puls, R., Petoumenos, K., Emery, S., Mellett, N. A., Mundra, P. A., Meikle, P. J., Hoy, J. F. & for the ALTAIR Study Group, 1 Aug 2018, In : PLoS ONE. 13, 8, 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Chronic kidney disease in Australian Human Immunodeficiency Virus-infected patients: Analysis of the Australian HIV Observational Database

Cheung, J., Puhr, R., Petoumenos, K., Cooper, D., Woolley, I. J., Gunathilake, M., Raymond, N., Varma, R., O'Connor, C. & Gracey, D. M., 1 Aug 2018, In : Nephrology. 23, 8, p. 778-786 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Comprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq)

Guérillot, R., Li, L., Baines, S., Howden, B., Schultz, M. B., Seemann, T., Monk, I., Pidot, S. J., Gao, W., Giulieri, S., Gonçalves da Silva, A., D'Agata, A., Tomita, T., Peleg, A. Y., Stinear, T. P. & Howden, B. P., 31 Aug 2018, In : Genome Medicine. 10, 1, 15 p., 63.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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Concomitant medication polypharmacy, interactions and imperfect adherence are common in Australian adults on suppressive antiretroviral therapy

Siefried, K. J., Mao, L., Cysique, L. A., Rule, J., Giles, M. L., Smith, D. E., McMahon, J., Read, T. R., Ooi, C., Tee, B. K., Bloch, M., De Wit, J. & Carr, A., 2 Jan 2018, In : AIDS. 32, 1, p. 35-48 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Consumer engagement critical to success in an Australian research project: Reflections from those involved

Synnot, A. J., Cherry, C. L., Summers, M. P., Stuckey, R., Milne, C. A., Lowe, DI. B. & Hill, S. J., 1 Jan 2018, In : Australian Journal of Primary Health. 24, 3, p. 197-203 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Contemporary analysis of functional immune recovery to opportunistic and vaccine-preventable infections after allogeneic haemopoietic stem cell transplantation

De Silva, H., Ffrench, R. A., Korem, M., Orlowski-Oliver, E., Curtis, D. J., Spencer, A., Avery, S., Patil, S. & Morrissey, C. O., 1 Jan 2018, In : Clinical and Translational Immunology. 7, 10, 16 p., e1040.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Convergent evolution driven by rifampin exacerbates the global burden of drug-resistant Staphylococcus aureus

Guérillot, R., da Silva, A. G., Monk, I., Giulieri, S., Tomita, T., Alison, E., Porter, J., Pidot, S., Gao, W., Peleg, A. Y., Seemann, T., Stinear, T. P. & Howden, B. P., 1 Jan 2018, In : mSphere. 3, 1, e00550-17.

Research output: Contribution to journalArticleResearchpeer-review

Delayed diagnosis and complications of predominantly antibody deficiencies in a cohort of Australian adults

Slade, C. A., Bosco, J. J., Giang, T. B., Kruse, E., Stirling, R. G., Cameron, P. U., Hore-Lacy, F., Sutherland, M. F., Barnes, S. L., Holdsworth, S., Ojaimi, S., Unglik, G. A., De Luca, J., Patel, M., McComish, J., Spriggs, K., Tran, Y., Auyeung, P., Nicholls, K., O'Hehir, R. E. & 4 othersHodgkin, P. D., Douglass, J. A., Bryant, V. L. & van Zelm, M. C., 14 May 2018, In : Frontiers in Immunology. 9, MAY, 9 p., 694.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Delays in presentation and diagnosis of pulmonary tuberculosis: a retrospective study of a tertiary health service in Western Melbourne, 2011–2014

Williams, E., Cheng, A. C., Lane, G. P. & Guy, S. D., 1 Feb 2018, In : Internal Medicine Journal. 48, 2, p. 184-193 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of outpatient antibiotics for urinary tract infections on antimicrobial resistance among commensal Enterobacteriaceae: A multinational prospective cohort study

Stewardson, A. J., Vervoort, J., Adriaenssens, N., Coenen, S., Godycki-Cwirko, M., Kowalczyk, A., Huttner, B. D., Lammens, C., Malhotra-Kumar, S., Goossens, H., Harbarth, S., on behalf of SATURN WP1 Study Group & SATURN WP3 Study Group, Sep 2018, In : Clinical Microbiology and Infection. 24, 9, p. 972–979 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with e coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance

Harris, P. N. A., Tambyah, P. A., Lye, D. C., Mo, Y., Lee, T. H., Yilmaz, M., Alenazi, T. H., Arabi, Y., Falcone, M., Bassetti, M., Righi, E., Rogers, B. A., Kanj, S., Bhally, H., Iredell, J., Mendelson, M., Boyles, T. H., Looke, D., Miyakis, S., Walls, G. & 15 othersAl Khamis, M., Zikri, A., Crowe, A., Ingram, P., Daneman, N., Griffin, P., Athan, E., Lorenc, P., Baker, P., Roberts, L., Beatson, S. A., Peleg, A. Y., Harris-Brown, T., Paterson, D. L. & for the MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN), 11 Sep 2018, In : JAMA - Journal of the American Medical Association. 320, 10, p. 984-994 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of the Australian National Hand Hygiene Initiative after 8 years on infection control practices, health-care worker education, and clinical outcomes: a longitudinal study

Grayson, M. L., Stewardson, A. J., Russo, P. L., Ryan, K. E., Olsen, K. L., Havers, S. M., Greig, S., Cruickshank, M. & on behalf of Hand Hygiene Australia and the National Hand Hygiene Initiative, 1 Nov 2018, In : Lancet Infectious Diseases. 18, 11, p. 1269-1277 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Eliminating hepatitis C: The importance of frequent testing of people who inject drugs in high-prevalence settings

Scott, N., Sacks-Davis, R., Pedrana, A., Doyle, J., Thompson, A. & Hellard, M., 1 Dec 2018, In : Journal of Viral Hepatitis. 25, 12, p. 1472-1480 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Elucidation of the pharmacokinetic/pharmacodynamic determinants of fosfomycin activity against Pseudomonas aeruginosa using a dynamic in vitro model

Bilal, H., Peleg, A. Y., McIntosh, M. P., Styles, I. K., Hirsch, E. B., Landersdorfer, C. B. & Bergen, P. J., 1 Jun 2018, In : Journal of Antimicrobial Chemotherapy. 73, 6, p. 1570-1578 9 p.

Research output: Contribution to journalArticleResearchpeer-review