Research Output 1984 2019

2017
2 Citations (Scopus)

Molecular simulations of carbohydrates with a fucose-binding Burkholderia ambifaria lectin suggest modulation by surface residues outside the fucose-binding pocket

Dingjan, T., Imberty, A., Pérez, S., Yuriev, E. & Ramsland, P. A., 21 Jun 2017, In : Frontiers in Pharmacology. 8, JUN, 393.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Negative correlation between circulating Cd4+Foxp3+Cd127 regulatory T Cells and subsequent antibody responses to infant measles vaccine but not diphtheria–tetanus–pertussis vaccine implies a regulatory role

Ndure, J., Noho-Konteh, F., Adetifa, J. U., Cox, M., Barker, P. F., Le, M. T., Sanyang, L. C., Drammeh, A., Whittle, H. C., Clarke, E., Plebanski, M., Rowland-Jones, S. L. & Flanagan, K. L., 14 Aug 2017, In : Frontiers in Immunology. 8, AUG, 12 p., 921.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Neoadjuvant interferons: Critical for effective PD-1–based immunotherapy in TNBC

Brockwell, N. K., Owen, K. L., Zanker, D., Spurling, A., Rautela, J., Duivenvoorden, H. M., Baschuk, N., Caramia, F., Loi, S., Darcy, P. K., Lim, E. & Parker, B. S., 1 Oct 2017, In : Cancer Immunology Research. 5, 10, p. 871-884 14 p.

Research output: Contribution to journalArticleResearchpeer-review

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36 Citations (Scopus)

Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes

Kraakman, M. J., Lee, M. K. S., Al-Sharea, A., Dragoljevic, D., Barrett, T. J., Montenont, E., Basu, D., Heywood, S. E., Kammoun, H. L., Flynn, M., Whillas, A., Hanssen, N. M. J., Febbraio, M. A., Westein, E., Fisher, E. A., Chin-Dusting, J., Cooper, M. E., Berger, J. S., Goldberg, I. J., Nagareddy, P. R. & 1 others, Murphy, A. J., 1 Jun 2017, In : Journal of Clinical Investigation. 127, 6, p. 2133-2147 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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New Trends in Anti-Cancer Therapy: Combining Conventional Chemotherapeutics with Novel Immunomodulators

Wilson, A. L., Plebanski, M. & Stephens, A., 29 Aug 2017, (Accepted/In press) In : Current Medicinal Chemistry. 27 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

7 Citations (Scopus)

Nicotinic acetylcholine receptor alpha 7 stimulation dampens splenic myelopoiesis and inhibits atherogenesis in Apoe−/− mice

Al-Sharea, A., Lee, M. K. S., Whillas, A., Flynn, M. C., Chin-Dusting, J. & Murphy, A. J., 1 Oct 2017, In : Atherosclerosis. 265, p. 47-53 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

No interactive effects of sex and persistent cytomegalovirus on immune phenotypes in young children: The generation R study

Jansen, M. A. E., Van Den Heuvel, D., Jaddoe, V. W. V., Moll, H. A. & Van Zelm, M. C., 15 Mar 2017, In : Journal of Infectious Diseases. 215, 6, p. 883-888 6 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Opposing roles of B lymphocyte subsets in atherosclerosis

Kyaw, T., Tipping, P., Bobik, A. & Toh, B. H., 2 Jan 2017, In : Autoimmunity. 50, 1, p. 52-56 5 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

14 Citations (Scopus)

Optimization of 2-anilino 4-amino substituted quinazolines into potent antimalarial agents with oral in vivo activity

Gilson, P. R., Tan, C., Jarman, K. E., Lowes, K. N., Curtis, J. M., Nguyen, W., Di Rago, A. E., Bullen, H. E., Prinz, B., Duffy, S., Baell, J. B., Hutton, C. A., Jousset Subroux, H., Crabb, B. S., Avery, V. M., Cowman, A. F. & Sleebs, B. E., 9 Feb 2017, In : Journal of Medicinal Chemistry. 60, 3, p. 1171-1188 18 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice

Kammoun, H. L., Allen, T. L., Henstridge, D. C., Kraakman, M. J., Peijs, L., Rose-John, S. & Febbraio, M. A., 20 Jun 2017, In : PLoS ONE. 12, 6, 13 p., e0179099.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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26 Citations (Scopus)

Oxygen therapy for interstitial lung disease: A systematic review

Bell, E. C., Cox, N. S., Goh, N., Glaspole, I., Westall, G. P., Watson, A. & Holland, A. E., 1 Jan 2017, In : European Respiratory Review. 26, 143, 160080.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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Pathogenesis of Macrovascular Complications in Diabetes

Gray, S. P., Di Marco, E., Candido, R., Cooper, M. E. & Jandeleit-Dahm, K. A. M., 2017, Textbook of Diabetes. Holt, R. I. G., Cockram, C. S., Flyvbjerg, A. & Goldstein, B. J. (eds.). Wiley-Blackwell, p. 611-628 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Peanut allergy: Biomolecular characterization for development of a peanut T-cell epitope peptide therapy

Rolland, J. M., Prickett, S. R. & O’Hehir, R. E., 1 Jan 2017, Food Allergy: Molecular and Clinical Practice. Lopata, A. L. (ed.). 1st ed. Boca Raton FL USA: CRC Press, p. 351-372 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

32 Citations (Scopus)

Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression

McHugh, D., Caduff, N., Barros, M. H. M., Rämer, P. C., Raykova, A., Murer, A., Landtwing, V., Quast, I., Styles, C. T., Spohn, M., Fowotade, A., Delecluse, H. J., Papoudou-Bai, A., Lee, Y. M., Kim, J. M., Middeldorp, J., Schulz, T. F., Cesarman, E., Zbinden, A., Capaul, R. & 6 others, White, R. E., Allday, M. J., Niedobitek, G., Blackbourn, D. J., Grundhoff, A. & Münz, C., 12 Jul 2017, In : Cell Host and Microbe. 22, 1, p. 61-73.e7

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

Counihan, N. A., Chisholm, S. A., Bullen, H. E., Srivastava, A., Sanders, P. R., Jonsdottir, T. K., Weiss, G. E., Ghosh, S., Crabb, B. S., Creek, D. J., Gilson, P. R. & De Koning-Ward, T. F., 2 Mar 2017, In : eLife. 6, 31 p., e23217.

Research output: Contribution to journalArticleResearchpeer-review

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4 Citations (Scopus)

Preparation of platelet concentrates for research and transfusion purposes

Greening, D. W., Simpson, R. J. & Sparrow, R. L., 2017, Serum/Plasma Proteomics: Methods and Protocols. 2nd ed. Humana Press, Vol. 1619. p. 31-42 12 p. (Methods in Molecular Biology; vol. 1619).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

9 Citations (Scopus)

Red blood cell components: Time to revisit the sources of variability

Sparrow, R. L., 1 Mar 2017, In : Blood Transfusion. 15, 2, p. 116-125 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2 Citations (Scopus)
Open Access
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11 Citations (Scopus)

SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages

Luo, L., Bokil, N. J., Wall, A. A., Kapetanovic, R., Lansdaal, N. M., Marceline, F., Burgess, B. J., Tong, S. J., Guo, Z., Alexandrov, K., Ross, I. L., Hibbs, M. L., Stow, J. L. & Sweet, M. J., 18 Jan 2017, In : Nature Communications. 8, 14 p., 14133.

Research output: Contribution to journalArticleResearchpeer-review

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25 Citations (Scopus)

Sex and gender differences in the outcomes of vaccination over the life course

Flanagan, K. L., Fink, A. L., Plebanski, M. & Klein, S. L., 6 Oct 2017, In : Annual Review of Cell and Developmental Biology. 33, p. 577-599 23 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Sex-differential heterologous (non-specific) effects of vaccines: an emerging public health issue that needs to be understood and exploited

Flanagan, K. L. & Plebanski, M., 2 Jan 2017, In : Expert Review of Vaccines. 16, 1, p. 5-13 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

6 Citations (Scopus)

Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation

Molloy, C. P., Yao, Y., Kammoun, H., Bonnard, T., Hoefer, T., Alt, K., Tovar-Lopez, F., Rosengarten, G., Ramsland, P. A., van der Meer, A. D., van den Berg, A., Murphy, A. J., Hagemeyer, C. E., Peter, K. & Westein, E., May 2017, In : Journal of Thrombosis and Haemostasis. 15, 5, p. 972-982 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Synthetic nanoparticles that promote tumor necrosis factor receptor 2 expressing regulatory T cells in the lung and resistance to allergic airways inflammation

Mohamud, R., LeMasurier, J. S., Boer, J. C., Sieow, J. L., Rolland, J. M., O'Hehir, R. E., Hardy, C. L. & Plebanski, M., 22 Dec 2017, In : Frontiers in Immunology. 8, DEC, 1812.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

T and B cell markers in dried blood spots of neonates with congenital cytomegalovirus infection: B cell numbers at birth are associated with long-term outcomes

Rovito, R., Korndewal, M. J., Van Zelm, M. C., Ziagkos, D., Wessels, E., Van Der Burg, M., Kroes, A. C. M., Langerak, A. W. & Vossen, A. C. T. M., 1 Jan 2017, In : Journal of Immunology. 198, 1, p. 102-109 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Targeting activated platelets: A unique and potentially universal approach for cancer imaging

Yap, M. L., McFadyen, J. D., Wang, X., Zia, N. A., Hohmann, J. D., Ziegler, M., Yao, Y., Pham, A., Harris, M., Donnelly, P. S., Hogarth, P. M., Pietersz, G. A., Lim, B. & Peter, K., 2017, In : Theranostics. 7, 10, p. 2565-2574 10 p.

Research output: Contribution to journalArticleResearchpeer-review

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55 Citations (Scopus)

Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy

Beavis, P. A., Henderson, M. A., Giuffrida, L., Mills, J. K., Sek, K., Cross, R. S., Davenport, A. J., John, L. B., Mardiana, S., Slaney, C. Y., Johnstone, R. W., Trapani, J. A., Stagg, J., Loi, S., Kats, L., Gyorki, D. E., Kershaw, M. H. & Darcy, P. K., 1 Mar 2017, In : Journal of Clinical Investigation. 127, 3, p. 929-941 13 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Tetraspanin microdomains control localized protein kinase C signaling in B cells

Zuidscherwoude, M., Dunlock, V. M. E., Van Den Bogaart, G., Van Deventer, S. J., van der Schaaf, A., Van Oostrum, J., Goedhart, J., In't Hout, J., Hämmerling, G. J., Tanaka, S., Nadler, A., Schultz, C., Wright, M. D., Adjobo-Hermans, M. J. W. & Van Spriel, A. B., 9 May 2017, In : Science Signaling. 10, 478, 15 p., aag2755.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence

Cassar, L., Nicholls, C., Pinto, A. R., Chen, R., Wang, L., Li, H. & Liu, J. P., 1 Jan 2017, In : Protein & Cell. 8, 1, p. 39-54 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

The autophagy machinery restrains iNKT cell activation through CD1D1 internalization

Keller, C. W., Loi, M., Ewert, S., Quast, I., Theiler, R., Gannagé, M., Münz, C., De Libero, G., Freigang, S. & Lünemann, J. D., 3 Jun 2017, In : Autophagy. 13, 6, p. 1025-1036 12 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

The BTG2-PRMT1 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex

Dolezal, E., Infantino, S., Drepper, F., Börsig, T., Singh, A., Wossning, T., Fiala, G. J., Minguet, S., Warscheid, B., Tarlinton, D. M., Jumaa, H., Medgyesi, D. & Reth, M., 19 Jul 2017, In : Nature Immunology. 18, 8, p. 911-920 10 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells

Vuckovic, S., Vandyke, K., Rickards, D. A., Mccauley Winter, P., Brown, S. H. J., Mitchell, T. W., Liu, J., Lu, J., Askenase, P. W., Yuriev, E., Capuano, B., Ramsland, P., Hill, G. R., Zannettino, A. C. W. & Hutchinson, A. T., May 2017, In : British Journal of Haematology. 177, 3, p. 423-440 18 p.

Research output: Contribution to journalArticleResearchpeer-review

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13 Citations (Scopus)

The contributions of lung macrophage and monocyte heterogeneity to influenza pathogenesis

Duan, M., Hibbs, M. L. & Chen, W., 1 Mar 2017, In : Immunology and Cell Biology. 95, 3, p. 225-235 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2 Citations (Scopus)

The Economics of Malaria Vaccine Development

Plebanski, M. & Flanagan, K. L., 1 Mar 2017, In : Trends in Parasitology. 33, 3, p. 154-156 3 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

46 Citations (Scopus)

The evidence of benefits of exercise training in interstitial lung disease: a randomised controlled trial

Dowman, L. M., McDonald, C. F., Hill, C. J., Lee, A. L., Barker, K., Boote, C., Glaspole, I., Goh, N. S. L., Southcott, A. M., Burge, A. T., Gillies, R., Martin, A. & Holland, A. E., 1 Jul 2017, In : Thorax. 72, 7, p. 610-619 10 p.

Research output: Contribution to journalArticleResearchpeer-review

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9 Citations (Scopus)

The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites

Charnaud, S. C., Dixon, M. W. A., Nie, C. Q., Chappell, L., Sanders, P. R., Nebl, T., Hanssen, E., Berriman, M., Chan, J., Blanch, A. J., Beeson, J. G., Rayner, J. C., Przyborski, J. M., Tilley, L., Crabb, B. S. & Gilson, P. R., 1 Jul 2017, In : PLoS ONE. 12, 7, 22 p., e0181656.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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9 Citations (Scopus)

The life and death of immune cell types: The role of BCL-2 anti-apoptotic molecules

Carrington, E. M., Tarlinton, D. M., Gray, D. H., Huntington, N. D., Zhan, Y. & Lew, A. M., 1 Nov 2017, In : Immunology and Cell Biology. 95, 10, p. 870-877 8 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

6 Citations (Scopus)

The role of vitamin D on circulating memory T cells in children: The Generation R study

Looman, K. I. M., Jansen, M. A. E., Voortman, T., van den Heuvel, D., Jaddoe, V. W. V., Franco, O. H., van Zelm, M. C. & Moll, H. A., 1 Sep 2017, In : Pediatric Allergy and Immunology. 28, 6, p. 579-587 9 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)

Traffic-related air pollution exposure is associated with allergic sensitization, asthma, and poor lung function in middle age

Bowatte, G., Lodge, C. J., Knibbs, L. D., Lowe, A. J., Erbas, B., Dennekamp, M., Marks, G. B., Giles, G., Morrison, S., Thompson, B., Thomas, P. S., Hui, J., Perret, J. L., Abramson, M. J., Walters, H., Matheson, M. C. & Dharmage, S. C., Jan 2017, In : Journal of Allergy and Clinical Immunology. 139, 1, p. 122-129 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Transient reduction in IgA+ and IgG+ memory B cell numbers in young EBV-seropositive children: The generation R study

van den Heuvel, D., Jansen, M. A. E., Bell, A. I., Rickinson, A. B., Jaddoe, V. W. V., van Dongen, J. J. M., Moll, H. A. & van Zelm, M. C., 1 Apr 2017, In : Journal of leukocyte biology. 101, 4, p. 949-956 8 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Understanding CD8+ T-cell responses toward the native and alternate HLA-A02:01-restricted WT1 epitope

Nguyen, T., Tan, A. CL., Xiang, S. D., Goubier, A., Harland, K. L., Clemens, E. B., Plebanski, M. & Kedzierska, K., 1 Jan 2017, In : Clinical and Translational Immunology. 6, 3, 12 p., e134.

Research output: Contribution to journalArticleResearchpeer-review

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35 Citations (Scopus)

Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition

Hearps, A. C., Tyssen, D., Srbinovski, D., Bayigga, L., Diaz, D. J. D., Aldunate, M., Cone, R. A., Gugasyan, R., Anderson, D. J. & Tachedjian, G., 1 Nov 2017, In : Mucosal Immunology. 10, 6, p. 1480-1490 11 p.

Research output: Contribution to journalArticleResearchpeer-review

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10 Citations (Scopus)

Viral Vector Malaria Vaccines Induce High-Level T Cell and Antibody Responses in West African Children and Infants

Bliss, C. M., Drammeh, A., Bowyer, G., Sanou, G. S., Jagne, Y. J., Ouedraogo, O., Edwards, N. J., Tarama, C., Ouedraogo, N., Ouedraogo, M., Njie-jobe, J., Diarra, A., Afolabi, M. O., Tiono, A. B., Yaro, J. B., Adetifa, U. J., Hodgson, S. H., Anagnostou, N. A., Roberts, R., Duncan, C. J. A. & 12 others, Cortese, R., Viebig, N. K., Leroy, O., Lawrie, A. M., Flanagan, K. L., Kampmann, B., Imoukhuede, E. B., Sirima, S. B., Bojang, K. A., Hill, A. V. S., Nébié, I. & Ewer, K. J., 1 Feb 2017, In : Molecular Therapy. 25, 2, p. 547-559 13 p.

Research output: Contribution to journalArticleResearchpeer-review

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15 Citations (Scopus)

Who's at risk of thunderstorm asthma? The ryegrass pollen trifecta and lessons learnt from the Melbourne thunderstorm epidemic

Lee, J., Kronborg, C., O'Hehir, R. E. & Hew, M., 1 Nov 2017, In : Respiratory Medicine. 132, p. 146-148 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2016
12 Citations (Scopus)

Acceptability and feasibility of point-of-care CD4 testing on HIV continuum of care in low and middle income countries: A systematic review

Pham, M. D., Agius, P. A., Romero, L., McGlynn, P., Anderson, D., Crowe, S. M. & Luchters, S., 2 Aug 2016, In : BMC Health Services Research. 16, 1, 343.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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18 Citations (Scopus)

A CD1d-dependent lipid antagonist to NKT cells ameliorates atherosclerosis in ApoE-/- mice by reducing lesion necrosis and inflammation

Li, Y., Kanellakis, P., Hosseini, H., Cao, A., Deswaerte, V., Tipping, P., Toh, B. H., Bobik, A. & Kyaw, T., 1 Feb 2016, In : Cardiovascular Research. 109, 2, p. 305-317 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Alteration of early dendritic cell activation by cancer cell lines predisposes immunosuppression, which cannot be reversed by TLR4 stimulation

Kong, Y. Y., Fuchsberger, M., Plebanski, M. & Apostolopoulos, V., 2016, In : Acta Biochimica et Biophysica Sinica. 48, 12, p. 1101-1111 11 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)
Open Access
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5 Citations (Scopus)

Anaphylaxis to oats after cutaneous sensitization by oatmeal in skin products used for the treatment of atopic dermatitis

Radhakrishna, N., Prickett, S., Phan, T., Rolland, J. M., Puy, R. & O'Hehir, R. E., 1 Jan 2016, In : Journal of Allergy and Clinical Immunology: In Practice. 4, 1, p. 152-153 2 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Antibodies that block or activate mouse b cell activating factor of the tumor necrosis factor (TNF) family (baff), respectively, induce b cell depletion or b cell hyperplasia

Kowalczyk-Quintas, C., Schuepbach-Mallepell, S., Vigolo, M., Willen, L., Tardivel, A., Smulski, C. R., Zheng, T. S., Gommerman, J., Hess, H., Gottenberg, J. E., Mackay, F., Donze, O. & Schneider, P., 16 Sep 2016, In : Journal of Biological Chemistry. 291, 38, p. 19826-19834 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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