Research Output 1984 2019

Article

Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice

Daglas, M., Draxler, D. F., Ho, H., McCutcheon, F., Galle, A., Au, A. E., Larsson, P., Gregory, J., Alderuccio, F., Sashindranath, M. & Medcalf, R. L., 29 Oct 2019, In : Cell Reports. 29, 5, p. 1178-1191.e6 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumors and metastases

Yap, M. L., McFadyen, J. D., Wang, X., Ziegler, M., Chen, Y. C., Willcox, A., Nowell, C. J., Scott, A. M., Sloan, E. K., Hogarth, P. M., Pietersz, G. A. & Peter, K., 1 Jan 2019, In : Theranostics. 9, 4, p. 1154-1169 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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12 Citations (Scopus)

Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity

Edwards, E. S. J., Bier, J., Cole, T. S., Wong, M., Hsu, P., Berglund, L. J., Boztug, K., Lau, A., Gostick, E., Price, D. A., O'Sullivan, M., Meyts, I., Choo, S., Gray, P., Holland, S. M., Deenick, E. K., Uzel, G. & Tangye, S. G., 1 Jan 2018, (Accepted/In press) In : Journal of Allergy and Clinical Immunology.

Research output: Contribution to journalArticleResearchpeer-review

85 Citations (Scopus)

Activation and migration of CD8 T cells in the intestinal mucosa

Kim, S-K., Reed, D. S., Heath, W. R., Carbone, F. R. & Lefrancois, L., 1997, In : Journal of Immunology. p. 4295 - 4306 12 p.

Research output: Contribution to journalArticleResearchpeer-review

82 Citations (Scopus)

Activation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation

Walker, F., Kato, A., Gonez, L. J., Hibbs, M. L., Pouliot, N., Levitzki, A. & Burgess, A. W., 1 Jan 1998, In : Molecular and Cellular Biology. 18, 12, p. 7192-7204 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
302 Citations (Scopus)

Activation of thymic regeneration in mice and humans following androgen blockade

Sutherland, J. S., Goldberg, G. L., Hammett, M. V., Uldrich, A. P., Berzins, S. P., Heng, T. S. P., Blazar, B. R., Millar, J. L., Malin, M., Chidgey, A. P. & Boyd, R. L., 2005, In : Journal of Immunology. 175, 4, p. 2741 - 2753 13 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Activin inhibits telomerase activity in cancer

Katik, I., Mackenzie-kludas, C., Nicholls, C., Jiang, F-X., Zhou, S., Li, H. & Liu, J-P., 2009, In : Biochemical and Biophysical Research Communications. 389, 4, p. 668 - 672 5 p.

Research output: Contribution to journalArticleResearchpeer-review

104 Citations (Scopus)

Adenosine receptor 2A blockade increases the efficacy of anti-PD-1 through enhanced antitumor T-cell responses

Beavis, P. A., Milenkovski, N., Henderson, M. A., John, L. B., Allard, B., Loi, S., Kershaw, M. H., Stagg, J. & Darcy, P. K., 1 May 2015, In : Cancer Immunology Research. 3, 5, p. 506-517 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
8 Citations (Scopus)

Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study

Menditto, E., Costa, E., Midão, L., Bosnic-Anticevich, S., Novellino, E., Bialek, S., Briedis, V., Mair, A., Rajabian-Soderlund, R., Arnavielhe, S., Bedbrook, A., Czarlewski, W., Annesi-Maesano, I., Anto, J. M., Devillier, P., De Vries, G., Keil, T., Sheikh, A., Orlando, V., Larenas-Linnemann, D. & 47 others, Cecchi, L., De Feo, G., Illario, M., Stellato, C., Fonseca, J., Malva, J., Morais-Almeida, M., Pereira, A. M., Todo-Bom, A. M., Kvedariene, V., Valiulis, A., Bergmann, K. C., Klimek, L., Mösges, R., Pfaar, O., Zuberbier, T., Cardona, V., Mullol, J., Papadopoulos, N. G., Prokopakis, E. P., Bewick, M., Ryan, D., Roller-Wirnsberger, R. E., Tomazic, P. V., Cruz, A. A., Kuna, P., Samolinski, B., Fokkens, W. J., Reitsma, S., Bosse, I., Fontaine, J. F., Laune, D., Haahtela, T., Toppila-Salmi, S., Bachert, C., Hellings, P. W., Melén, E., Wickman, M., Bindslev-Jensen, C., Eller, E., O'Hehir, R. E., Cingi, C., Gemicioğlu, B., Kalayci, O., Ivancevich, J. C., Bousquet, J. & the MASK group, Apr 2019, In : Clinical and Experimental Allergy. 49, 4, p. 442-460 19 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

A diagnostic test for scabies: IgE specificity for a recombinant allergen of Sarcoptes scabiei

Jayaraj, R., Hales, B., Viberg, L., Pizzuto, S., Holt, D., Rolland, J. M., O'Hehir, R. E., Currie, B. J. & Walton, S., 2011, In : Diagnostic Microbiology and Infectious Disease. 71, 4, p. 403 - 407 5 p.

Research output: Contribution to journalArticleResearchpeer-review

165 Citations (Scopus)

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity

Nagareddy, P. R., Kraakman, M. J., Masters, S. L., Stirzaker, R. A., Gorman, D. J., Grant, R. W., Dragoljevic, D., Hong, E. S., Abdel-Latif, A., Smyth, S. S., Choi, S. H., Korner, J., Bornfeldt, K. E., Fisher, E. A., Dixit, V. D., Tall, A. R., Goldberg, I. J. & Murphy, A. J., 2014, In : Cell Metabolism. 19, 5, p. 821 - 835 15 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Administration of porcine interleukin-3 induces increased levels of blood eosinophils

Morris, K. R., Bean, A. G. D., Bruce, M. P., Broadway, M. M., O'Neil, T. E., Andrew, M. E., Emmins, J. J. & Strom, D. G., 2008, In : Journal of Interferon and Cytokine Research. 28, 7, p. 435 - 444 10 p.

Research output: Contribution to journalArticleResearchpeer-review

A dominant V beta bias in the CTL response after HSV-1 infection is determined by peptide residues predicted to also interact with the TCR beta-chain CDR3

Turner, S. J. & Carbone, F. R., 1998, In : Molecular Immunology. p. 307 - 316 10 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Adoptive immunotherapy combined with intratumoral TLR agonist delivery eradicates established melanoma in mice

Amos, S. M., Pegram, H. J., Westwood, J. A., John, L. B., Devaud, C., Clarke, C. J. P., Restifo, N. P., Smyth, M. J., Darcy, P. K. & Kershaw, M. H., 2011, In : Cancer Immunology Immunotherapy. 60, 5, p. 671 - 683 13 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Advance care planning education in pulmonary rehabilitation: a qualitative study exploring participant perspectives

Burge, A., Lee, A., Nicholes, M., Purcell, S., Miller, B., Norris, N., McArdle, S., Sandilands, S. & Holland, A. E., 2013, In : Palliative Medicine. 27, 6, p. 509-516 8 p.

Research output: Contribution to journalArticleResearchpeer-review

88 Citations (Scopus)

Advanced glycation end products are direct modulators of beta-cell function

Coughlan, M. T., Yap, F., Tong, D., Andrikopoulos, S., Gasser, A., Thallas-Bonke, V., Webster, D., Miyazaki, J., Kay, T., Slattery, R., Kaye, D., Drew, B., Kingwell, B., Fourlanos, S., Groop, P-H., Harrison, L., Knip, M. & Forbes, J., 2011, In : Diabetes. 60, 10, p. 2523 - 2532 10 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Advanced glycation end products as environmental risk factors for the development of type 1 diabetes

Yap, F., Kantharidis, P., Coughlan, M. T., Slattery, R. M. & Forbes, J. M., 2012, In : Current Drug Targets. 13, 4, p. 526 - 540 15 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Advanced glycation urinary protein-bound biomarkers and severity of diabetic nephropathy in man

Coughlan, M. T., Patel, S. K., Jerums, G., Penfold, S. A., Nguyen, T. V., Sourris, K. C., Panagiotopoulos, S., Srivastava, P. M., Cooper, M. E., Burrell, L. M., MacIsaac, R. J. & Forbes, J. M., Oct 2011, In : American Journal of Nephrology. 34, 4, p. 347-355 9 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Advances in development of hypoallergenic latex immunotherapy

Rolland, J. M., Drew, A. C. & O'Hehir, R. E., 2005, In : Current Opinion in Allergy and Clinical Immunology. 5, 6, p. 544 - 551 8 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Advances in our understanding of the pathophysiology of Type 1 diabetes: lessons from the NOD mouse

Jayasimhan, A., Mansour, K. P. & Slattery, R. M., 2014, In : Clinical Science. 126, 1, p. 1 - 18 18 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Adverse events associated with rush hymenoptera venom immunotherapy

Westall, G. P., Thien, F., Czarny, D., O'Hehir, R. E. & Douglass, J. A., 2001, In : Medical Journal of Australia. 174, p. 227 - 230 4 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway

Dunkley, S., Arthur, J. F., Evans, S., Gardiner, E. E., Shen, Y. & Andrews, R. K., 2007, In : British Journal of Haematology. 137, 6, p. 569 - 577 9 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)

A fatal thrombotic disorder associated with an acquired inhibitor of protein C

Mitchell, C. A., Rowell, J. A., Hau, L., Young, J. P. & Salem, H. H., 1987, In : New England Journal of Medicine. 317, 26, p. 1638-1642 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Affinity maturation in the B-cell response to antigen

Tarlinton, D., Light, A., Smith, K. & Nossal, G. J. V., 1 Jan 2000, In : Immunologist. 8, 1-2, p. 9-11 3 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

A flowcytometric analysis to efficiently quantify multiple innate immune cells and T Cell subsets in human blood

Draxler, D. F., Madondo, M. T., Hanafi, G., Plebanski, M. & Medcalf, R. L., 1 Apr 2017, In : Cytometry Part A. 91, 4, p. 336-350 15 p.

Research output: Contribution to journalArticleResearchpeer-review

567 Citations (Scopus)

A fresh look at tumor immunosurveillance and immunotherapy

Smyth, M. J., Godfrey, D. I. & Trapani, J. A., 2001, In : Nature Immunology. 2, 4, p. 293 - 299 7 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

A functional 14-3-3{zeta}-independent association of PI3-kinase with glycoprotein Ib{alpha}, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex

Mu, F-T., Andrews, R. K., Arthur, J. F., Munday, A. D., Cranmer, S. L., Jackson, S., Stomski, F. C., Lopez, A. F. & Berndt, M. C., 2008, In : Blood. 111, 9, p. 4580 - 4587 8 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood

Blanco, E., Pérez-Andrés, M., Arriba-Méndez, S., Contreras-Sanfeliciano, T., Criado, I., Pelak, O., Serra-Caetano, A., Romero, A., Puig, N., Remesal, A., Torres Canizales, J., López-Granados, E., Kalina, T., Sousa, A. E., van Zelm, M., van der Burg, M., van Dongen, J. J. M., Orfao, A. & on behalf of the EuroFlow PID group, 1 Jun 2018, In : Journal of Allergy and Clinical Immunology. 141, 6, p. 2208-2219.e16 28 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Age-dependent pre-vaccination immunity affects the immunogenicity of varicella zoster vaccination in middle-aged adults

van der Heiden, M., de Rond, L. G. H., van Zelm, M. C., Berbers, G. A. M., Boots, A. M. H. & Buisman, A. M., 23 Jan 2018, In : Frontiers in Immunology. 9, JAN, 10 p., 46.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Age-related T cell responses to allergens in childhood

Smart, J. M., Suphioglu, C. & Kemp, A. S., 2003, In : Clinical and Experimental Allergy. 33, 3, p. 317 - 324 8 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

A glucose-6-phosphate isomerase peptide induces T and B cell-dependent chronic arthritis in C57BL/10 mice: arthritis without reactive oxygen species and complement

Pizzolla, A., Wing, K. & Holmdahl, R., 2013, In : American Journal of Pathology. 183, 4, p. 1144 - 1155 12 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)

Agonist peptide modulates T cell selection thresholds through qualitative and quantitative shifts in CD8 co-receptor expression

Chidgey, A. & Boyd, R. L., 1997, In : International Immunology. p. 1527 - 1536 10 p.

Research output: Contribution to journalArticleResearchpeer-review

A Human Monoclonal IgE Antibody Defines a Highly Allergenic Fragment of th Major Timothy Grass Pollen Allergen, Phl p 5: Molecular, Immunological, and Structural Characterization of the Epitope-Containing Domain

Flicker, S., Vrtala, S., Steinberger, P., Vangelista, L., Bufe, A., Petersen, A., Ghannadan, M., Sperr, W. R., Valent, P., Norderhaug, L., Bohle, B., Stockinger, H., Suphioglu, C., Ong, E. K., Kraft, D. & Valenta, R., 2000, In : Journal of Immunology. p. 3849 - 3859 11 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

A kinase-dead allele of lyn attenuates autoimmune disease normally associated with lyn deficiency

Verhagen, A., Wallace, M., Goradia, A., Jones, S. A., Croom, H., Metcalf, D., Collinge, J., Maxwell, M., Hibbs, M., Alexander, W., Hilton, D., Kile, B. & Starr, R., 2009, In : Journal of Immunology. 182, p. 2020 - 2029 10 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Alagebrium reduces glomerular fibrogenesis and inflammation beyond preventing RAGE activation in diabetic apolipoprotein E knockout mice

Watson, A. M. D., Gray, S. P., Jiaze, L., Soro-Paavonen, A., Wong, B., Cooper, M. E., Bierhaus, A., Pickering, R., Tikellis, C., Tsorotes, D., Thomas, M. C. & Jandeleit-Dahm, K. A. M., Aug 2012, In : Diabetes. 61, 8, p. 2105-2113 9 p.

Research output: Contribution to journalArticleResearchpeer-review

114 Citations (Scopus)

A large family of endosome-localized proteins related to sorting nexin 1

Teasdale, R., Loci, D., Houghton, F., Karlsson, L. & Gleeson, P. A., 2001, In : Biochemical Journal. 358, p. 7 - 16 10 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Aliskiren reduces vascular pathology in diabetic retinopathy and oxygen-induced retinopathy in the transgenic (mRen-2)27 rat

Wilkinson-Berka, J., Tan, G., Binger, K., Sutton, L., McMaster, K., Deliyanti, D., Perera, G., Campbell, D. & Miller, A., 2011, In : Diabetologia. 54, 10, p. 2724 - 2735 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Allergen immunotheraphy: current and new therapeutic strategies

Rolland, J. M., Douglass, J. & O'Hehir, R., 2000, In : Expert Opinion on Investigational Drugs. p. 515 - 527 13 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Allergen immunotherapy: Current and new therapeutic strategies

Rolland, J. M. & O'Hehir, R. E., 2002, In : Allergology International. 51, p. 221 - 231 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Allergen-induced airway reactions in atopic asthmatics correlate with allergen-specific IL-5 response by BAL cells

Tang, C., Rolland, J. M., Ward, C., Quan, B. & Walters, E. H., 1997, In : Respirology. p. 45 - 55 11 p.

Research output: Contribution to journalArticleResearchpeer-review

68 Citations (Scopus)

Allergen-related approaches to immunotherapy

Rolland, J. M., Gardner, L. M. & O'Hehir, R. E., 2009, In : Pharmacology and Therapeutics. 121, Dec 7, p. 273 - 284 11 p.

Research output: Contribution to journalArticleResearchpeer-review

332 Citations (Scopus)

Allergic rhinitis and its impact on asthma (ARIA): achievements in 10 years and future needs

Bousquet, J., Schunemann, H. J., Samolinski, B., Demoly, P., Baena-Cagnani, C. E., Bachert, C., Bonini, S., Boulet, L. P., Bousquet, P. J., Brozek, J., Canonica, G. W. A., Casale, T. B., Cruz, A. A. U., Fokkens, W. J., Fonseca, J., van Wijk, R. G., Grouse, L., Haahtela, T., Khaltaev, N., Kuna, P. & 30 others, Lockey, R. F., Lodrup Carlsen, K. C., Mullol, J., Naclerio, R. M., O'Hehir, R. E., Ohta, K., Palkonen, S., Papadopoulos, N. G., Passalacqua, G. P., Pawankar, R. U., Price, D. B., Ryan, D. P., Simons, F. E. R., Togias, A. G., Williams, D. M., Yorgancioglu, A., Yusuf, O. M., Aberer, W., Adachi, M., Agache, I. O., Ait-Khaled, N., Akdis, C. A., Andrianarisoa, A., Annesi-Maesano, I., Ansotegui, I. J., Baiardini, I., Bateman, E. D., Bedbrook, A., Beghe, B. & Beji, M., 2012, In : Journal of Allergy and Clinical Immunology. 130, 5, p. 1049 - 1062 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2788 Citations (Scopus)

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update

Bousquet, J., Khaltaev, N., Cruz, A. A., Denburg, J., Fokkens, W. J., Togias, A., Zuberbier, T., Baena-Cagnani, C. E., Canonica, G. W., Weel, C. V., Agache, I., Ait-Khaled, N., Bachert, C., Blaiss, M. S., Bonini, S., Boulet, L. P., Bousquet, P. J., Camargos, P., Carlsen, K. H., Chen, Y. & 41 others, Custovic, A., Dahl, R., Demoly, P., Douagui, H., Durham, S. R., Wijk, R. G. V., Kalayci, O., Kaliner, A., Kim, Y. Y., Kowalski, L., Kuna, P., Le, L. T., Lemiere, C., Li, J., Lockey, R. F., Mavale-Manuel, S., Meltzer, E. O., Mohammad, Y., Mullol, J., Naclerio, R., O'Hehir, R. E., Ohta, K., Ouedraogo, S., Palkonen, S., Papadopoulos, N., Passalacqua, G., Pawankar, R., Popov, T. A., Rabe, K. F., Rosado-Pinto, J., Scadding, G. K., Simons, F. E. R., Toskala, E., Valovirta, E., van Cauwenberge, P., Wang, D. Y., Wickman, M., Yawn, B. P., Yorgancioglu, A., Yusuf, O. M. & Zar, H., 2008, In : Allergy. 63, Suppl 86, p. 8 - 160 153 p.

Research output: Contribution to journalArticleOther

7 Citations (Scopus)

Allosteric modulation of the HIV-1 gp120-gp41 association site by adjacent gp120 variable region 1 (V1) N-glycans linked to neutralization sensitivity

Drummer, H. E., Hill, M. K., Maerz, A. L., Wood, S. J., Ramsland, P. A., Mak, J. & Poumbourios, P., 2013, In : PLoS ONE. 9, 4, 18 p., e1003218.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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100 Citations (Scopus)

ALT-946 and aminoguanidine, inhibitors of advanced glycation, improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat

Wilkinson-Berka, J., Kelly, D. J., Koerner, S. M., Jaworski, K. A., Davis, B., Thallas, V. & Cooper, M. E., 2002, In : Diabetes. 51, p. 3283 - 3289 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Alteration of early dendritic cell activation by cancer cell lines predisposes immunosuppression, which cannot be reversed by TLR4 stimulation

Kong, Y. Y., Fuchsberger, M., Plebanski, M. & Apostolopoulos, V., 2016, In : Acta Biochimica et Biophysica Sinica. 48, 12, p. 1101-1111 11 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Altered expression of fibrogenic growth factors in IgA nephropathy and focal and segmental glomerulosclerosis

Stein-Oakley, A. N., Maguire, J., Dowling, J. P., Perry, G. & Thomson, N. M., 1997, In : Kidney International. p. 195 - 204 10 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Alternative coreceptor requirements for efficient CCR5- and CXCR4-mediated HIV-1 entry into macrophages

Cashin, K., Roche, M., Sterjovski, J., Ellett, A., Gray, L. R., Cunningham, A., Ramsland, P., Churchill, M. & Gorry, P., 2011, In : Journal of Virology. 85, 20, p. 10699 - 10709 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
13 Citations (Scopus)

Alternative lengthening of telomeres in hTERT-inhibited laryngeal cancer cells.

Chen, W., Xiao, B-K., Liu, J-P., Chen, S-M. & Tao, Z-Z., 2010, In : Cancer Science. 101, 8, p. 1769 - 1776 8 p.

Research output: Contribution to journalArticleOther

37 Citations (Scopus)

Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit

Perugini, M., Brown, A., Salerno, D., Booker, G., Stojkoski, C., Hercus, T., Lopez, A., Hibbs, M., Gonda, T. & D'Andrea, R., 2010, In : Blood. 115, 16, p. 3346 - 3353 8 p.

Research output: Contribution to journalArticleResearchpeer-review