Hudson Institute - Department of Molecular and Translational Science

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2016

Optimizing lung aeration at birth using a sustained inflation and positive pressure ventilation in preterm rabbits

Te Pas, A. B., Kitchen, M. J., Lee, K., Wallace, M. J., Fouras, A., Lewis, R. A., Yagi, N., Uesugi, K. & Hooper, S. B., 1 Jul 2016, In : Pediatric Research. 80, 1, p. 85-91 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

Prepubertal Di-n-Butyl phthalate exposure alters Sertoli and Leydig cell function and lowers bone density in adult male mice

Bielanowicz, A., Johnson, R. W., Goh, H., Moody, S. C., Poulton, I. J., Croce, N., Loveland, K. L., Hedger, M. P., Sims, N. A. & Itman, C., Jul 2016, In : Endocrinology. 157, 7, p. 2595-2603 9 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

Tate, M. D., Ong, J. DH., Dowling, J. K., McAuley, J. L., Robertson, A. B., Latz, E., Drummond, G. R., Cooper, M. A., Hertzog, P. J. & Mansell, A., 10 Jun 2016, In : Scientific Reports. 6, 8 p., 27912.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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49 Citations (Scopus)

Reconstitution of degenerated ovine lumbar discs by STRO-3-positive allogeneic mesenchymal precursor cells combined with pentosan polysulfate

Oehme, D., Ghosh, P., Goldschlager, T., Itescu, S., Shimon, S., Wu, J., McDonald, C., Troupis, J. M., Rosenfeld, J. V. & Jenkin, G., 1 May 2016, In : Journal of Neurosurgery: Spine. 24, 5, p. 715-726 12 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency

Cagnone, G., Tsai, T-S., Makanji, Y., Matthews, P. M., Gould, J. A., Bonkowski, M. S., Elgass, K., Wong, A. S. A., Wu, L. E., McKenzie, M., Sinclair, D. A. & St John, J. C., 2016, In : Scientific Reports. 6, p. 1 - 15 15 p., 23229.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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35 Citations (Scopus)

Segregation of naturally occurring mitochondrial DNA variants in a mini-pig model

Cagnone, G., Tsai, T-S., Srirattana, K., Rossello, F., Powell, D. R., Rohrer, G., Cree, L., Trounce, I. A. & St John, J. C., Mar 2016, In : Genetics. 202, 3, p. 931-944 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
13 Citations (Scopus)

Serum levels of GDF15 are reduced in preeclampsia and the reduction is more profound in late-onset than early-onset cases

Chen, Q., Wang, Y., Zhao, M., Hyett, J., da Silva Costa, F. & Nie, G., 1 Jul 2016, In : Cytokine. 83, p. 226-230 5 p.

Research output: Contribution to journalArticleResearchpeer-review

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5 Citations (Scopus)

Severity and timing: How prenatal stress exposure affects glial developmental, emotional behavioural and plasma neurosteroid responses in guinea pig offspring

Bennett, G. A., Palliser, H. K., Walker, D. & Hirst, J., 1 Aug 2016, In : Psychoneuroendocrinology. 70, p. 47-57 11 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Single sustained inflation followed by ventilation leads to rapid cardiorespiratory recovery but causes cerebral vascular leakage in asphyxiated near-term lambs

Sobotka, K., Hooper, S. B., Crossley, K. J., Ong, T. S. L., Schmolzer, G. M., Barton, S. K., McDougall, A. RA., Miller, S. L., Tolcos, M., Klingenberg, C. & Polglase, G., 1 Jan 2016, In : PLoS ONE. 11, 1, 14 p., 0146574.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice

Winbanks, C. E., Murphy, K. T., Bernardo, B. C., Qian, H., Liu, Y., Sepulveda, P. V., Beyer, C., Hagg, A., Thomson, R. E., Chen, J. L., Walton, K. L., Loveland, K. L., McMullen, J. R., Rodgers, B. D., Harrison, C. A., Lynch, G. S. & Gregorevic, P., 20 Jul 2016, In : Science Translational Medicine. 8, 348, 12 p., 348ra98.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Subfascial endoscopic perforator surgery (SEPS) for treating and preventing recurrence of venous leg ulcers (Protocol)

Lin, Z. C., Loveland, P. M., Johnston, R. V., Bruce, M. & Weller, C., 26 Apr 2016, In : Cochrane Database of Systematic Reviews. 2016, 4, p. 1 - 14 14 p., CD012164.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Surgical margins in head and neck squamous cell carcinoma: Effect of heat artifact on immunohistochemistry as a future tool for assessment

Sigston, E. A. W., Longano, A., Strzelecki, A. T. & Williams, B. R. G., Sep 2016, In : Head & Neck. 38, 9, p. 1401-1406 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Targeting interleukin-11 receptor-α impairs human Endometrial cancer cell proliferation and invasion in vitro and reduces tumor growth and metastasis in vivo

Winship, A. L., Van Sinderen, M., Donoghue, J., Rainczuk, K. & Dimitriadis, E., Apr 2016, In : Molecular Cancer Therapeutics. 15, 4, p. 720-730 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
14 Citations (Scopus)

The establishment of DOHaD working groups in Australia and New Zealand

Prescott, S. L., Allen, K., Armstrong, K., Collins, C., Dickinson, H., Gardiner, K. J., Jacka, F. N., Jasoni, C., Moore, T., Moritz, K. M., Muhlhausler, B. S., Siero, W., Sim, K., Nanan, R., Saffery, R., Singh, G., Vickers, M. H. & Craig, J. M., 1 Oct 2016, In : Journal of Developmental Origins of Health and Disease. 7, 5, p. 433-439 7 p.

Research output: Contribution to journalArticleOtherpeer-review

5 Citations (Scopus)

The kinase activity of PKR represses inflammasome activity

Yim, H. C. H., Wang, D., Yu, L., White, C. L., Faber, P. W., Williams, B. R. G. & Sadler, A. J., 1 Mar 2016, In : Cell Research. 26, 3, p. 367-379 13 p.

Research output: Contribution to journalArticleResearchpeer-review

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15 Citations (Scopus)
9 Citations (Scopus)

Therapeutic targeting of the IL-6 trans-signaling/mechanistic target of rapamycin complex 1 axis in pulmonary emphysema

Ruwanpura, S. M., McLeod, L., Dousha, L. F., Seow, H. J., Alhayyani, S., Tate, M. D., Deswaerte, V., Brooks, G. D., Bozinovski, S., MacDonald, M., Garbers, C., King, P. T., Bardin, P. G., Vlahos, R., Rose-John, S., Anderson, G. P. & Jenkins, B. J., 15 Dec 2016, In : American Journal of Respiratory and Critical Care Medicine. 194, 12, p. 1494-1505 12 p.

Research output: Contribution to journalArticleResearchpeer-review

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21 Citations (Scopus)

The relationship between mitochondrial DNA haplotype and the reproductive capacity of domestic pigs (Sus scrofa domesticus)

Tsai, T-S., Rajasekar, S. & St. John, J. C., 18 May 2016, In : BMC Genetics. 17, 1, 17 p., 67.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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19 Citations (Scopus)

The SMAC mimetic, LCL-161, reduces survival in aggressive MYC-driven lymphoma while promoting susceptibility to endotoxic shock

West, A. C., Martin, B. P., Andrews, D. A., Hogg, S. J., Banerjee, A., Grigoriadis, G., Johnstone, R. W. & Shortt, J., 4 Apr 2016, In : Oncogenesis. 5, 6 p., e216.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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13 Citations (Scopus)

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

Carroll, E. C., Jin, L., Mori, A., Muñoz-Wolf, N., Oleszycka, E., Moran, H. B. T., Mansouri, S., McEntee, C. P., Lambe, E. M., Agger, E. M., Andersen, P., Cunningham, C., Hertzog, P., Fitzgerald, K. A., Bowie, A. G. & Lavelle, E. C., 15 Mar 2016, In : Immunity. 44, 3, p. 597-608 12 p.

Research output: Contribution to journalArticleResearchpeer-review

152 Citations (Scopus)

Tissue response to collagen containing polypropylene meshes in an ovine vaginal repair model

Darzi, S., Urbankova, I., Su, K., White, J., Lo, C., Alexander, D. M., Werkmeister, J. A., Gargett, C. E. & Deprest, J., 15 Jul 2016, In : Acta Biomaterialia. 39, p. 114-123 10 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Tob1 is expressed in developing and adult gonads and is associated with the P-body marker, Dcp2

Shapouri, F., Saeidi, S., de Iongh, R. U., Casagranda, F., Western, P. S., McLaughlin, E. A., Sutherland, J. M., Hime, G. R. & Familari, M., 1 May 2016, In : Cell and Tissue Research. 364, 2, p. 443-451 9 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Toll-IL1 receptor-mediated innate immune responses vary across HBV genotype and predict treatment response to pegylated-IFN in HBeAg-positive CHB patients

Visvanathan, K., Lang, T., Ryan, K., Wilson, R., Skinner, N. A., Thompson, A. J. V., Ahn, S. H., Weilert, F., Abbott, W., Gane, E., Colledge, D., Li, K., Locarnini, S., Mansell, A. & Revill, P. A., 1 Mar 2016, In : Journal of Viral Hepatitis. 23, 3, p. 170-179 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Total PC activity is increased in uterine lavage of post-menopausal endometrial but not ovarian cancer patients

Heng, S., Stephens, A. N., Jobling, T. W. & Nie, G-Y., 2016, In : Journal of Cancer. 7, 13, p. 1812 - 1814 3 p.

Research output: Contribution to journalArticleOtherpeer-review

2 Citations (Scopus)

Transcriptomic analysis of stage 1 versus advanced adult granulosa cell tumors

Alexiadis, M., Chu, S., Leung, D., Gould, J. A., Jobling, T. & Fuller, P. J., 2016, In : Oncotarget. 7, 12, p. 14207 - 14219 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

Transcytosis of IL-11 and Apical Redirection of gp130 Is Mediated by IL-11α Receptor

Monhasery, N., Moll, J., Cuman, C., Franke, M., Lamertz, L., Nitz, R., Görg, B., Häussinger, D., Lokau, J., Floss, D. M., Piekorz, R., Dimitriadis, E., Garbers, C. & Scheller, J., 26 Jul 2016, In : Cell Reports. 16, 4, p. 1067-1081 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Translocation and dissemination of commensal bacteria in post-stroke infection

Stanley, D., Mason, L. J., MacKin, K. E., Srikhanta, Y. N., Lyras, D., Prakash, M. D., Nurgali, K., Venegas, A., Hill, M. D., Moore, R. J. & Wong, C. H. Y., 1 Nov 2016, In : Nature Medicine. 22, 11, p. 1277-1284 8 p.

Research output: Contribution to journalArticleResearchpeer-review

65 Citations (Scopus)

Urogenital development in Pallister-Hall syndrome is disrupted in a cell-lineage-specific manner by constitutive expression of GLI3 repressor

Blake, J., Hu, D., Cain, J. E. & Rosenblum, N. D., 1 Feb 2016, In : Human Molecular Genetics. 25, 3, p. 437-447 11 p., ddv483.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Uropathogenic Escherichia coli causes fibrotic remodelling of the epididymis

Michel, V., Duan, Y., Stoschek, E., Bhushan, S., Middendorff, R., Young, J. M., Loveland, K. L., Kretser, D. M. D., Hedger, M. P. & Meinhardt, A., 1 Sep 2016, In : Journal of Pathology. 240, 1, p. 15-24 10 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

WNT/β-catenin and p27/FOXL2 differentially regulate supporting cell proliferation in the developing ovary

Gustin, S. E., Hogg, K., Stringer, J. M., Rastetter, R. H., Pelosi, E., Miles, D. C., Sinclair, A. H., Wilhelm, D. & Western, P. S., 15 Apr 2016, In : Developmental Biology. 412, 2, p. 250-260 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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15 Citations (Scopus)
2015

A comparison of high-frequency jet ventilation and synchronised intermittent mandatory ventilation in preterm lambs

Musk, G. C., Polglase, G., Bunnell, J. B., Nitsos, I., Tingay, D. G. & Pillow, J., 2015, In : Pediatric Pulmonology. 50, 12, p. 1286 - 1293 8 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer

Samardzija, C., Luwor, R. B., Volchek, M., Quinn, M. A., Findlay, J. J. K. & Ahmed, N., 2015, In : Molecular Cancer. 14, p. 1 - 19 19 p., 152.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans

Yan, E. B., Frugier, T. J., Lim, C. K., Heng, B., Sundaram, G., Tan, M., Rosenfeld, J. V., Walker, D. W., Guillemin, G. J. & Morganti-Kossmann, M. C., 12 Dec 2015, In : Journal of Neuroinflammation. 12, 1, 17 p., 110.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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33 Citations (Scopus)

Activin A contributes to the development of hyperoxia-induced lung injury in neonatal mice

Lim, R. S. W., Muljadi, R. C. M., Koulaeva, E., Vosdoganes, P., Chan, S. T., Acharya, R., Gurusinghe, S., Ritvos, O., Pasternack, A. & Wallace, E. M., 2015, In : Pediatric Research. 77, 6, p. 749 - 756 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Activin and NADPH-oxidase in preeclampsia: insights from in vitro and murine studies

Lim, R., Acharya, R., Delpachitra, P., Hobson, S., Sobey, C. G., Drummond, G. R. & Wallace, E. M., 1 Jan 2015, In : American Journal of Obstetrics and Gynecology. 212, 1, p. 86.e1 - 86.e12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion

Aghababaei, M., Hogg, K., Persu, S., Robinson, W. P. & Beristain, A. G., 2015, In : Cell Death and Differentiation. 22, 12, p. 1970 - 1984 15 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Aldosterone-mediated renal sodium transport requires intact mineralocorticoid receptor DNA binding in the mouse

Cole, T. J., Terella, L. R., Morgan, J., Alexiadis, M., Yao, Y-Z., Enriori, P., Young, M. J. & Fuller, P. J., 2015, In : Endocrinology. 156, 8, p. 2958 - 2968 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Allopregnanolone and social stress: regulation of the stress response in early pregnancy in pigs

Rault, J-L., Plush, K., Yawno, T. & Langendijk, P., 2015, In : Stress-The International Journal on the Biology of Stress. 18, 5, p. 569 - 577 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Alphaxalone reformulated: a water-soluble intravenous anesthetic preparation in sulfobutyl-ether-(beta)-cyclodextrin

Goodchild, C. S., Serrao, J. M., Kolosov, A. & Boyd, B. J., 2015, In : Anesthesia and Analgesia. 120, 5, p. 1025 - 1031 7 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

A meta-analysis of somatic KCNJ5 K(+) channel mutations in 1636 patients with an aldosterone-producing adenoma

Lenzini, L., Rossitto, G., Maiolino, G., Letizia, C., Funder, J. W. & Rossi, G. P., 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 8, p. 1089 - 1095 7 p.

Research output: Contribution to journalArticleResearchpeer-review

83 Citations (Scopus)

Amnion cell-mediated immune modulation following bleomycin challenge: controlling the regulatory T cell response

Tan, J., Chan, S. T., Lo, C. Y-W., Deane, J. A., McDonald, C., Bernard, C. C. A., Wallace, E. M. & Lim, R. S. W., 2015, In : Stem Cell Research and Therapy. 6, 1, p. 1 - 12 12 p., 8.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
29 Citations (Scopus)

Analysis of ER-mitochondria contacts using correlative fluorescence microscopy and soft X-ray tomography of mammalian cells

Elgass, K., Smith, E. A., LeGros, M. A., Larabell, C. A. & Ryan, M. T., 2015, In : Journal of Cell Science. 128, 15, p. 2795 - 2804 10 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

An authentic animal model of the very preterm infant on nasal continuous positive airway pressure

Dargaville, P. A., Lavizzari, A., Padoin, P., Black, D., Zonneveld, E., Perkins, E., Sourial, M., Rajapaksa, A. E., Davis, P. G., Hooper, S. B., Moss, T. J. M., Polglase, G. & Tingay, D. G., 2015, In : Intensive Care Medicine Experimental. 3, 12 p., 13.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Anti-cancer analogues ME-143 and ME-344 exert toxicity by directly inhibiting mitochondrial NADH: Ubiquinone oxidoreductase (Complex I)

Lim, S. C., Carey, K. T. & McKenzie, M., 2015, In : American Journal of Cancer Research. 5, 2, p. 689-701 13 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

A percutaneous fetal cardiac catheterization technique for pulmonary valvuloplasty and valvulotomy in a mid-gestation lamb model

Edwards, A., Veldman, A., Nitsos, I., Chan, Y., Brew, N., Teoh, M., Menahem, S., Schranz, D. & Wong, F. Y-W., 2015, In : Prenatal Diagnosis. 35, 1, p. 74 - 80 7 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Apert syndrome: temporal lobe abnormalities on fetal brain imaging

Stark, Z., McGillivray, G., Sampson, A. K., Palma-Dias, R., Edwards, A., Said, J. M., Whiteley, G. & Fink, A. M., 2015, In : Prenatal Diagnosis. 35, 2, p. 179 - 182 4 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

A phase 1c trial comparing the efficacy and safety of a new aqueous formulation of alphaxalone with propofol

Monagle, J., Siu, W. L., Worrell, J., Goodchild, C. S. & Serrao, J. M., 2015, In : Anesthesia and Analgesia. 121, 4, p. 914 - 924 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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22 Citations (Scopus)

A randomised crossover trial of clinical algorithm for oxygen saturation targeting in preterm infants with frequent desaturation episodes

Clarke, A., Yeomans, E., Elsayed, K., Medhurst, A., Berger, P. J., Skuza, E. M. & Tan, K. H. H., 2015, In : Neonatology. 107, 2, p. 130 - 136 7 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

A review of current animal models for the study of cervical dysplasia and cervical carcinoma

Larmour, L. I., Jobling, T. W. & Gargett, C. E., 1 Oct 2015, In : International Journal of Gynecological Cancer. 25, 8, p. 1345-1352 8 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer

Wang, X., Simpson, E. R. & Brown, K. A., 2015, In : Journal of Steroid Biochemistry and Molecular Biology. 153, p. 35 - 44 10 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)