Hudson Institute - Department of Molecular and Translational Science

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2017

Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse

Dunleavy, J. E. M., Okuda, H., O’Connor, A. E., Merriner, D. J., O’Donnell, L., Jamsai, D., Bergmann, M. & O’Bryan, M. K., 14 Nov 2017, In : PLoS Genetics. 13, 11, 28 p., e1007078.

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8 Citations (Scopus)

Lumbar microdiscectomy and post-operative activity restrictions: A protocol for a single blinded randomised controlled trial

Daly, C. D., Lim, K. Z., Lewis, J. A., Saber, K., Molla, M., Bar-Zeev, N. & Goldschlager, T., 20 Jul 2017, In : BMC Musculoskeletal Disorders. 18, 1, 8 p., 312.

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2 Citations (Scopus)

Lung ultrasound immediately after birth to describe normal neonatal transition: An observational study

Blank, D. A., Farouk Kamlin, C. O., Rogerson, S. R., Fox, L. M., Lorenz, L., Kane, S. C., Polglase, G. R., Hooper, S. B. & Davis, P. G., 28 Jun 2017, In : Archives of Disease in Childhood. 103, 2, p. F157-F162 6 p.

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8 Citations (Scopus)

Manipulating the mitochondrial genome to enhance cattle embryo development

Srirattana, K. & St. John, J. C., 1 Jul 2017, In : G3: Genes, Genomes, Genetics. 7, 7, p. 2065-2080 16 p.

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5 Citations (Scopus)

Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood

Li, Y., Salamonsen, L. A., Hyett, J., Da Silva Costa, F. & Nie, G-Y., 4 Jul 2017, In : Scientific Reports. 7, 1, 4627.

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4 Citations (Scopus)

Mechanism of interferon-stimulated gene induction in HIV-1- infected macrophages

Nasr, N., Alshehri, A. A., Wright, T. K., Shahid, M., Heiner, B. M., Harman, A. N., Botting, R. A., Helbig, K. J., Beard, M. R., Suzuki, K., Kelleher, A. D., Hertzog, P. & Cunningham, A. L., 1 Oct 2017, In : Journal of Virology. 91, 20, 19 p., e00744-17.

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9 Citations (Scopus)

Menopause is a determinant of breast aromatase expression and its associations with BMI, inflammation, and systemic markers

Brown, K. A., Iyengar, N. M., Zhou, X. K., Gucalp, A., Subbaramaiah, K., Wang, H., Giri, D. D., Morrow, M., Falcone, D. J., Wendel, N. K., Winston, L. A., Pollak, M., Dierickx, A., Hudis, C. A. & Dannenberg, A. J., 1 May 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 5, p. 1692-1701 10 p.

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22 Citations (Scopus)

Methylomic and phenotypic analysis of the ModH5 phasevarion of Helicobacter pylori

Srikhanta, Y. N., Gorrell, R. J., Power, P., Tsyganov, K., Boitano, M., Clark, T. A., Korlach, J., Hartland, E. L., Jennings, M. P. & Kwok, T., 1 Dec 2017, In : Scientific Reports. 7, 1, 14 p., 16140.

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8 Citations (Scopus)

MIR-127 promotes EMT and stem-like traits in lung cancer through a feed-forward regulatory loop

Shi, L., Wang, Y., Lu, Z., Zhang, H., Zhuang, N., Wang, B., Song, Z., Chen, G., Huang, C., Xu, D., Zhang, Y., Zhang, W. & Gao, Y., 23 Mar 2017, In : Oncogene. 36, 12, p. 1631-1643 13 p.

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30 Citations (Scopus)

Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns

Lee, W. T., Sun, X., Tsai, T-S., Johnson, J. L., Gould, J. A., Garama, D. J., Gough, D. J., McKenzie, M., Trounce, I. A. & St John, J. C., 1 Jan 2017, In : Cell Death Discovery. 3, 11 p., 17062.

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10 Citations (Scopus)

Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells

Vaghjiani, V., Cain, J. E., Lee, W., Vaithilingam, V., Tuch, B. E. & St John, J. C., 15 Oct 2017, In : Stem Cells and Development. 26, 20, p. 1505-1519 15 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Monocytes and dendritic cells are the primary sources of interleukin 37 in human immune cells

Rudloff, I., Cho, S. X., Lao, J. C., Ngo, D., McKenzie, M., Nold-Petry, C. A. & Nold, M. F., 1 Apr 2017, In : Journal of leukocyte biology. 101, 4, p. 901-911 11 p.

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18 Citations (Scopus)

Multiple soluble TGF-β receptors in addition to soluble endoglin are elevated in preeclamptic serum and they synergistically inhibit TGF-β signaling

Wang, Y., Chen, Q., Zhao, M., Walton, K., Harrison, C. & Nie, G., 1 Aug 2017, In : Journal of Clinical Endocrinology and Metablism. 102, 8, p. 3065-3074 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Naturally existing isoforms of miR-222 have distinct functions

Yu, F., Pillman, K. A., Neilsen, C. T., Toubia, J., Lawrence, D. M., Tsykin, A., Gantier, M. P., Callen, D. F., Goodall, G. J. & Bracken, C. P., 1 Jan 2017, In : Nucleic Acids Research. 45, 19, p. 11371-11385 15 p.

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24 Citations (Scopus)

N-cadherin identifies human endometrial epithelial progenitor cells by in vitro stem cell assays

Nguyen, H. P. T., Xiao, L., Deane, J. A., Tan, K. S., Cousins, F. L., Masuda, H., Sprung, C. N., Rosamilia, A. & Gargett, C. E., 1 Nov 2017, In : Human Reproduction. 32, 11, p. 2254-2268 15 p.

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19 Citations (Scopus)

Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort

Williams, T. A., Lenders, J. W. M., Mulatero, P., Burrello, J., Rottenkolber, M., Adolf, C., Satoh, F., Amar, L., Quinkler, M., Deinum, J., Beuschlein, F., Kitamoto, K. K., Pham, U., Morimoto, R., Umakoshi, H., Prejbisz, A., Kocjan, T., Naruse, M., Stowasser, M., Nishikawa, T. & 5 others, Young, W. F., Gomez-Sanchez, C. E., Funder, J. W., Reincke, M. & for the Primary Aldosteronism Surgery Outcome (PASO) investigators, 1 Sep 2017, In : The Lancet Diabetes and Endocrinology. 5, 9, p. 689-699 11 p.

Research output: Contribution to journalArticleResearchpeer-review

149 Citations (Scopus)

Outer membrane vesicles prime and activate macrophage inflammasomes and cytokine secretion in vitro and in vivo

Cecil, J. D., O'Brien-Simpson, N. M., Lenzo, J. C., Holden, J. A., Singleton, W. C. J., Perez-Gonzalez, A., Mansell, A. & Reynolds, E. C., 25 Aug 2017, In : Frontiers in Immunology. 8, AUG, 22 p., 1017.

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17 Citations (Scopus)

Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer

Yan, F., Ying, L., Li, X., Qiao, B., Meng, Q., Yu, L., Yuan, X., Ren, S. T., Chan, D. W., Shi, L., Ni, P., Wang, X., Xu, D. & Hu, Y., 2017, In : Oncotarget. 8, 29, p. 47020-47036 17 p.

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8 Citations (Scopus)

PB1-F2 peptide derived from avian influenza A virus H7N9 induces inflammation via activation of the NLRP3 inflammasome

Pinar, A., Dowling, J. K., Bitto, N. J., Robertson, A. A. B., Latz, E., Stewart, C. R., Drummond, G. R., Cooper, M. A., McAuley, J. L., Tate, M. D. & Mansell, A., 20 Jan 2017, In : Journal of Biological Chemistry. 292, 3, p. 826-836 11 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Pentosan polysulfate binds to STRO-1+ mesenchymal progenitor cells, is internalized, and modifies gene expression: A novel approach of pre-programing stem cells for therapeutic application requiring their chondrogenesis

Wu, J., Shimmon, S., Paton, S., Daly, C., Goldschlager, T., Gronthos, S., Zannettino, A. C. W. & Ghosh, P., 13 Dec 2017, In : Stem Cell Research and Therapy. 8, 1, 15 p., 278.

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Phosphoproteomic profiling reveals ALK and MET as novel actionable targets across synovial sarcoma subtypes

Fleuren, E. D. G., Vlenterie, M., Van Der Graaf, W. T. A., Hillebrandt-Roeffen, M. H. S., Blackburn, J., Ma, X., Chan, H., Magias, M. C., Van Erp, A., Van Houdt, L., Cebeci, S. A. S., Van De Ven, A., Flucke, U. E., Heyer, E. E., Thomas, D. M., Lord, C. J., Marini, K. D., Vaghjiani, V., Mercer, T. R., Cain, J. E. & 3 others, Wu, J., Versleijen-Jonkers, Y. M. H. & Daly, R. J., 15 Aug 2017, In : Cancer Research. 77, 16, p. 4279-4292 14 p.

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12 Citations (Scopus)

Porphyromonas gulae activates unprimed and gamma interferon-primed macrophages via the pattern recognition receptors Toll-like receptor 2 (TLR2), TLR4, and NOD2

Holden, J. A., O'Brien-Simpson, N. M., Lenzo, J. C., Orth, R. K. H., Mansell, A. & Reynolds, E. C., 1 Sep 2017, In : Infection and Immunity. 85, 9, 15 p., e00282-17.

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4 Citations (Scopus)

Positive regulatory interactions between YAP and Hedgehog signalling in skin homeostasis and BCC development in mouse skin in vivo

Akladios, B., Mendoza Reinoso, V., Cain, J. E., Wang, T., Lambie, D. L., Watkins, D. N. & Beverdam, A., 1 Aug 2017, In : PLoS ONE. 12, 8, 15 p., e0183178.

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9 Citations (Scopus)

PRC2 is required for extensive reorganization of H3K27me3 during epigenetic reprogramming in mouse fetal germ cells

Prokopuk, L., Stringer, J. M., Hogg, K., Elgass, K. D. & Western, P. S., 20 Feb 2017, In : Epigenetics and Chromatin. 10, 1, 20 p., 7.

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16 Citations (Scopus)

Regional reproductive quests: Cross-border reproductive travel among infertile Indonesian couples

Bennett, L. & Pangestu, M., 1 Aug 2017, In : Asia Pacific Viewpoint. 58, 2, p. 162-174 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Risk Factors for Hospital Readmission and Follow Up after NICU Discharge of Infants Born at Extremely Low Gestational Age in Metropolitan Melbourne

Doctor, T. N., Harnaen, E., Seith, B., Tan, K. & Craig, S., 2017, In : International Journal of Pediatric Research. 3, 1, 7 p., 028.

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Serum podocalyxin is significantly increased in early-onset preeclampsia and may represent a novel marker of maternal endothelial cell dysfunction

Chen, Q., Wang, Y., Li, Y., Zhao, M. & Nie, G., Nov 2017, In : Journal of Hypertension. 35, 11, p. 2287-2294 8 p.

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6 Citations (Scopus)

SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition

Nguyen, T. A., Smith, B. R. C., Tate, M. D., Belz, G. T., Barrios, M. H., Elgass, K. D., Weisman, A. S., Baker, P. J., Preston, S. P., Whitehead, L. W., Garnham, A. L., Lundie, R. J., Smyth, G. K., Pellegrini, M., O'Keeffe, M., Wicks, I. P., Masters, S. L., Hunter, C. P. & Pang, K. C., 19 Sep 2017, In : Immunity. 47, 3, p. 498-509 12 p.

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22 Citations (Scopus)

Signaling by TGF-betas in tubule cultures of adult rat testis

Chan, K. H., Galuska, S. P., Kudipudi, P. K., Riaz, M. A., Loveland, K. L. & Konrad, L., 2017, In : American Journal of Translational Research. 9, 3, p. 1173-1182 10 p., AJTR0034593.

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3 Citations (Scopus)

Simultaneous measurement of mitochondrial calcium and mitochondrial membrane potential in live cells by fluorescent microscopy

McKenzie, M., Lim, S. C. & Duchen, M. R., 24 Jan 2017, In : Journal of Visualized Experiments. 2017, 119, 6 p., e55166.

Research output: Contribution to journalArticleOtherpeer-review

6 Citations (Scopus)

Soluble Delta-like ligand 1 alters human endometrial epithelial cell adhesive capacity

Van Sinderen, M., Oyanedel, J., Menkhorst, E., Cuman, C., Rainczuk, K., Winship, A., Salamonsen, L., Edgell, T. & Dimitriadis, E., 2017, In : Reproduction, Fertility and Development. 29, 4, p. 694-702 9 p.

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3 Citations (Scopus)

Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling

Hughes, M. M., Lavrencic, P., Coll, R. C., Ve, T., Ryan, D. G., Williams, N. C., Menon, D., Mansell, A., Board, P. G., Mobli, M., Kobe, B. & O’Neill, L. A. J., 8 Aug 2017, In : Proceedings of the National Academy of Sciences. 114, 32, p. E6480-E6489 10 p.

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14 Citations (Scopus)

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling

Ve, T., Vajjhala, P. R., Hedger, A., Croll, T., Dimaio, F., Horsefield, S., Yu, X., Lavrencic, P., Hassan, Z., Morgan, G. P., Mansell, A., Mobli, M., O'Carroll, A., Chauvin, B., Gambin, Y., Sierecki, E., Landsberg, M. J., Stacey, K. J., Egelman, E. H. & Kobe, B., 7 Sep 2017, In : Nature Structural and Molecular Biology. 24, 9, p. 743-751 9 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling

Kedzierski, L., Tate, M., Hsu, A. C., Kolesnik, T. B., Linossi, E. M., Dagley, L., Dong, Z., Freeman, S., Infusini, G., Starkey, M. R., Bird, N. L., Chatfield, S. M., Babon, J. J., Huntington, N., Belz, G., Webb, A., Wark, P. AB., Nicola, N. A., Xu, J., Kedzierska, K. & 2 others, Hansbro, P. M. & Nicholson, S. E., 14 Feb 2017, In : eLife. 6, 27 p., e20444.

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25 Citations (Scopus)

Targeted Therapy for Severe Asthma: Identifying the Right Patients

Low, K. & Bardin, P. G., 1 Jun 2017, In : Molecular Diagnosis and Therapy. 21, 3, p. 235-247 13 p.

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4 Citations (Scopus)

Targeting the seeds of small cell lung cancer

Mahara, S. & Firestein, R., 1 Mar 2017, In : Annals of Translational Medicine. 5, 5, 113.

Research output: Contribution to journalArticleOtherpeer-review

Testis determination requires a specific FGFR2 isoform to repress FOXL2

Bagheri-Fam, S., Bird, A. D., Zhao, L., Ryan, J. M., Yong, M., Wilhelm, D., Koopman, P., Eswarakumar, V. P. & Harley, V. R., 1 Nov 2017, In : Endocrinology. 158, 11, p. 3832-3843 12 p.

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7 Citations (Scopus)

The human amnion epithelial cell secretome decreases hepatic fibrosis in mice with chronic liver fibrosis

Alhomrani, M., Correia, J., Zavou, M., Leaw, B., Kuk, N., Xu, R., Saad, M. I., Hodge, A., Greening, D. W., Lim, R. & Sievert, W., 24 Oct 2017, In : Frontiers in Pharmacology. 8, OCT, 13 p., 748.

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15 Citations (Scopus)

The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages

Alvarado, R., To, J., Lund, M. E., Pinar, A., Mansell, A., Robinson, M. W., O'Brien, B. A., Dalton, J. P. & Donnelly, S. M., 1 Jan 2017, In : FASEB Journal. 31, 1, p. 85-95 11 p.

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23 Citations (Scopus)

The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation

Dou, Y., Yim, H. C. H., Kirkwood, C. D., Williams, B. R. G. & Sadler, A. J., 15 Sep 2017, In : EMBO Journal. 36, 18, p. 2742-2757 16 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

The molecular characterization of porcine egg precursor cells

Tsai, T-S., Johnson, J., White, Y. & St John, J. C., 2017, In : Oncotarget. 8, 38, p. 63484-63505 22 p.

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The ovarian reserve is depleted during puberty in a hormonally driven process dependent on the pro-Apoptotic protein BMF

Liew, S. H., Nguyen, Q. N., Strasser, A., Findlay, J. K. & Hutt, K. J., 3 Aug 2017, In : Cell Death and Disease. 8, 8, e2971.

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10 Citations (Scopus)

The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer

McNamara, K. M., Oguro, S., Omata, F., Kikuchi, K., Guestini, F., Suzuki, K., Yang, Y., Abe, E., Hirakawa, H., Brown, K. A., Takanori, I., Ohuchi, N. & Sasano, H., 1 Jan 2017, In : Breast Cancer Research and Treatment. 161, 2, p. 213-227 15 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Therapeutically blocking Interleukin-11 Receptor-α enhances doxorubicin cytotoxicity in high grade type I endometrioid tumours

Winship, A., Van Sinderen, M., Rainczuk, K. & Dimitriadis, E., 2017, In : Oncotarget. 8, 14, p. 22716-22729 14 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer

Szczepny, A., Rogers, S., Jayasekara, W. S. N., Park, K., McCloy, R. A., Cochrane, C. R., Ganju, V., Cooper, W. A., Sage, J., Peacock, C. D., Cain, J. E., Burgess, A. & Watkins, D. N., 28 Sep 2017, In : Oncogene. 36, 39, p. 5544-5550 7 p.

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26 Citations (Scopus)

The significance of post-translational removal of α-DG-N in early stage endometrial cancer development

Heng, S., Evans, J., Salamonsen, L. A., Jobling, T. W. & Nie, G., 1 Jan 2017, In : Oncotarget. 8, 47, p. 81942-81952 11 p.

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3 Citations (Scopus)

The skin barrier function gene SPINK5 is associated with challenge-proven IgE-mediated food allergy in infants

Ashley, S. E., Tan, H. T. T., Vuillermin, P., Dharmage, S. C., Tang, M. L. K., Koplin, J., Gurrin, L. C., Lowe, A., Lodge, C., Ponsonby, A. -L., Molloy, J., Martin, P., Matheson, M. C., Saffery, R., Allen, K. J., Ellis, J. A., Martino, D., the HealthNuts team & on behalf of the Barwon Infant Study, the Melbourne Atopy Cohort study, the Peanut Allergen Threshold Study and the Probiotic and Peanut Oral ImmunoTherapy study, Sep 2017, In : Allergy. 72, 9, p. 1356 - 1364

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Topoisomerase 1 inhibition promotes cyclic GMP-AMP synthase-dependent antiviral responses

Pépin, G., Nejad, C., Ferrand, J., Thomas, B. J., Stunden, H. J., Sanij, E., Foo, C. H., Stewart, C. R., Cain, J. E., Bardin, P. G., Williams, B. R. G. & Gantier, M. P., 1 Sep 2017, In : mBio. 8, 5, 9 p., e01611-17.

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3 Citations (Scopus)

Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis

Srinivasan, S., Severa, M., Rizzo, F., Menon, R., Brini, E., Mechelli, R., Martinelli, V., Hertzog, P., Salvetti, M., Furlan, R., Martino, G., Comi, G., Coccia, E. & Farina, C., 1 Dec 2017, In : Scientific Reports. 7, 1, 9 p., 8981.

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6 Citations (Scopus)
5 Citations (Scopus)