Hudson Institute - Department of Molecular and Translational Science

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2018

Timeless Is a Novel Estrogen Receptor Co-activator Involved in Multiple Signaling Pathways in MCF-7 Cells

Magne Nde, C. B., Casas Gimeno, G., Docanto, M., Knower, K. C., Young, M. J., Buehn, J., Sayed, E. & Clyne, C. D., 11 May 2018, In : Journal of Molecular Biology. 430, 10, p. 1531-1543 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Trawler Web: An online de novo motif discovery tool for next-generation sequencing datasets

Dang, L. T., Tondl, M., Chiu, M. H. H., Revote, J., Paten, B., Tano, V., Tokolyi, A., Besse, F., Quaife-Ryan, G., Cumming, H., Drvodelic, M. J., Eichenlaub, M. P., Hallab, J. C., Stolper, J. S., Rossello, F. J., Bogoyevitch, M. A., Jans, D. A., Nim, H. T., Porrello, E. R., Hudson, J. E. & 1 others, Ramialison, M., 5 Apr 2018, In : BMC Genomics. 19, 1, 9 p., 238.

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2 Citations (Scopus)

Twin-to-twin transfusion syndrome neurodevelopmental follow-up study (neurodevelopmental outcomes for children whose twin-to-twin transfusion syndrome was treated with placental laser photocoagulation)

Bolch, C., Fahey, M., Reddihough, D., Williams, K., Reid, S., Guzys, A., Cole, S., Edwards, A., Fung, A., Hodges, R., Palma-Dias, R., Teoh, M. & Walker, S., 1 Aug 2018, In : BMC Pediatrics. 18, 1, 11 p., 256.

Research output: Contribution to journalArticleOtherpeer-review

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2 Citations (Scopus)

Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection

Richardson, A. M., Lewis, D. P., Kita, B., Ludlow, H., Groome, N. P., Hedger, M. P., de Kretser, D. M. & Lidbury, B. A., 12 Apr 2018, In : Journal of Translational Medicine. 16, 1, 11 p., 97.

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8 Citations (Scopus)

Zoonotic transfer of Clostridium difficile harboring antimicrobial resistance between farm animals and humans

Knetsch, C. W., Kumar, N., Forster, S. C., Connor, T. R., Browne, H. P., Harmanus, C., Sanders, I. M., Harris, S. R., Turner, L., Morris, T., Perry, M., Miyajima, F., Roberts, P., Pirmohamed, M., Songer, J. G., Weese, J. S., Indra, A., Corver, J., Rupnik, M., Wren, B. W. & 3 others, Riley, T. V., Kuijper, E. J. & Lawley, T. D., 1 Mar 2018, In : Journal of Clinical Microbiology. 56, 3, 8 p., e01384-17.

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29 Citations (Scopus)
2017

(-)-Epigallocatechin-3-gallate and atorvastatin treatment down-regulates liver fibrosis-related genes in non-alcoholic fatty liver disease

Ying, L., Yan, F., Zhao, Y., Gao, H., Williams, B. R. G., Hu, Y., Li, X., Tian, R., Xu, P. & Wang, Y., 1 Dec 2017, In : Clinical and Experimental Pharmacology and Physiology. 44, 12, p. 1180-1191 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor null mice: Informing cell-type-specific roles

Cole, T. J. & Young, M. J., 1 Jul 2017, In : Journal of Endocrinology. 234, 1, p. T83-T92 10 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Abnormal vocal cord movement in patients with and without airway obstruction and asthma symptoms

Low, K., Ruane, L., Uddin, N., Finlay, P., Lau, K. K., Hamza, K., Holmes, P. W., Hamilton, G. & Bardin, P. G., 1 Feb 2017, In : Clinical and Experimental Allergy. 47, 2, p. 200-207 8 p.

Research output: Contribution to journalArticleOtherpeer-review

16 Citations (Scopus)

Activation of cGAS-dependent antiviral responses by DNA intercalating agents

Pepin, G., Nejad, C., Thomas, B. J., Ferrand, J., McArthur, K., Bardin, P. G., Williams, B. R. G. & Gantier, M. P., 9 Jan 2017, In : Nucleic Acids Research. 45, 1, p. 198-205 8 p.

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9 Citations (Scopus)

Activin B is a novel biomarker for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis: A cross sectional study

Lidbury, B. A., Kita, B., Lewis, D. P., Hayward, S., Ludlow, H., Hedger, M. P. & de Kretser, D. M., 16 Mar 2017, In : Journal of Translational Medicine. 15, 1, 10 p., 60.

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12 Citations (Scopus)

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling

de Weerd, N. A., Matthews, A. Y., Pattie, P. R., Bourke, N. M., Lim, S. S., Vivian, J. P., Rossjohn, J. & Hertzog, P. J., 5 May 2017, In : Journal of Biological Chemistry. 292, 18, p. 7554-7565 13 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Allergic adverse events following 2015 seasonal influenza vaccine, Victoria, Australia

Clothier, H. J., Crawford, N. W., Russell, M. A. & Buttery, J. P., 18 May 2017, In : Eurosurveillance. 22, 20, p. 1-7 7 p., 30535.

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6 Citations (Scopus)

Altered SOX9 genital tubercle enhancer region in hypospadias

Sreenivasan, R., Gordon, C. T., Benko, S., de Iongh, R., Bagheri-Fam, S., Lyonnet, S. & Harley, V., Jun 2017, In : Journal of Steroid Biochemistry and Molecular Biology. 170, p. 28-38 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

An emergence framework of carcinogenesis

Sigston, E. A. W. & Williams, B. R. G., 14 Sep 2017, In : Frontiers in Oncology. 7, SEP, 14 p., 198.

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5 Citations (Scopus)

An in vitro model demonstrates the potential of neoplastic human germ cells to influence the tumour microenvironment

Klein, B., Schuppe, H. -C., Bergmann, M., Hedger, M. P., Loveland, B. E. & Loveland, K. L., Jul 2017, In : Andrology. 5, 4, p. 763-770 8 p.

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6 Citations (Scopus)

A non-canonical function of Ezh2 preserves immune homeostasis

Vasanthakumar, A., Xu, D., Lun, A. T. L., Kueh, A. J., van Gisbergen, K. P. J. M., Iannarella, N., Li, X., Yu, L., Wang, D., Williams, B. RG., Lee, S. C. W., Majewski, I. J., Godfrey, D. I., Smyth, G. K., Alexander, W. S., Herold, M. J., Kallies, A., Nutt, S. L. & Allan, R. S., 1 Apr 2017, In : EMBO Reports. 18, 4, p. 619-631 13 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

ATF3 repression of BCL-XL determines apoptotic sensitivity to HDAC inhibitors across tumor types

Chüeh, A. C., Tse, J. W. T., Dickinson, M., Ioannidis, P., Jenkins, L., Togel, L., Tan, B. S., Luk, I., Davalos-Salas, M., Nightingale, R., Thompson, M. R., Williams, B. R. G., Lessene, G., Lee, E. F., Fairlie, W. D., Dhillon, A. S. & Mariadason, J. M., 15 Sep 2017, In : Clinical Cancer Research. 23, 18, p. 5573-5584 12 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Auto-phosphorylation represses protein kinase R activity

Wang, D., De Weerd, N. A., Willard, B., Polekhina, G., Williams, B. R. G. & Sadler, A. J., 10 Mar 2017, In : Scientific Reports. 7, 15 p., 44340.

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1 Citation (Scopus)

Bacterial membrane vesicles transport their DNA cargo into host cells

Bitto, N. J., Chapman, R., Pidot, S., Costin, A., Lo, C., Choi, J., D'Cruze, T., Reynolds, E. C., Dashper, S. G., Turnbull, L., Whitchurch, C. B., Stinear, T. P., Stacey, K. J. & Ferrero, R. L., 1 Dec 2017, In : Scientific Reports. 7, 1, 11 p., 7072.

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35 Citations (Scopus)

Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma

Miller, A., McLeod, L., Alhayyani, S., Szczepny, A., Watkins, D. N., Chen, W., Enriori, P., Ferlin, W., Ruwanpura, S. & Jenkins, B. J., 25 May 2017, In : Oncogene. 36, 21, p. 3059-3066 8 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Cattle phenotypes can disguise their maternal ancestry

Srirattana, K., McCosker, K., Schatz, T. & St. John, J. C., 26 Jun 2017, In : BMC Genetics. 18, 1, 59.

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9 Citations (Scopus)

Chondroitin sulfate proteoglycan protein is stimulated by interleukin 11 and promotes endometrial epithelial cancer cell proliferation and migration

Winship, A., Van Sinderen, M., Heffernan-Marks, A. & Dimitriadis, E., 1 Mar 2017, In : International journal of oncology. 50, 3, p. 798-804 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Correlation between diffusion tensor imaging and histological brain injury in ventilated preterm lambs

Alahmari, D. M., Barton, S. K., Galinsky, R., Nitsos, I., Atik, A. A., Farrell, M. J., Pearson, J. T. & Polglase, G. R., 2017, In : Imaging in Medicine. 9, 3, p. 67-76 10 p.

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Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma

Greenall, S. A., Lim, Y. C., Mitchell, C. B., Ensbey, K. S., Stringer, B. W., Wilding, A. L., O'Neill, G. M., McDonald, K. L., Gough, D. J., Day, B. W. & Johns, T. G., 1 Jan 2017, In : Oncogenesis. 6, 5, 13 p., e336.

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21 Citations (Scopus)

Development and Biological Evaluation of a Photoactivatable Small Molecule Microtubule-Targeting Agent

Döbber, A., Phoa, A. F., Abbassi, R. H., Stringer, B. W., Day, B. W., Johns, T. G., Abadleh, M., Peifer, C. & Munoz, L., 13 Apr 2017, In : ACS Medicinal Chemistry Letters. 8, 4, p. 395-400 6 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Development of a pipeline for automated, high-throughput analysis of paraspeckle proteins reveals specific roles for importin α proteins

Major, A. T., Miyamoto, Y., Lo, C. Y., Jans, D. A. & Loveland, K. L., 27 Feb 2017, In : Scientific Reports. 7, 18 p., 43323.

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3 Citations (Scopus)

Dianthin-30 or gelonin versus monomethyl auristatin E, each configured with an anti-calcitonin receptor antibody, are differentially potent in vitro in high-grade glioma cell lines derived from glioblastoma

Gilabert-Oriol, R., Furness, S. G. B., Stringer, B. W., Weng, A., Fuchs, H., Day, B. W., Kourakis, A., Boyd, A. W., Hare, D. L., Thakur, M., Johns, T. G. & Wookey, P. J., 2017, In : Cancer Immunology Immunotherapy. 66, 9, p. 1217–1228 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Dimeric but not monomeric α-lactalbumin potentiates apoptosis by up regulation of ATF3 and reduction of histone deacetylase activity in primary and immortalised cells

Sharp, J. A., Brennan, A. J., Polekhina, G., Ascher, D. B., Lefevre, C. & Nicholas, K. R., 1 May 2017, In : Cellular Signalling. 33, p. 86-97 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Disruption of Serinc1, which facilitates serine-derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility

Chu, E. P. F., Elso, C. M., Pollock, A. H., Alsayb, M. A., Mackin, L., Thomas, H. E., Kay, T. W. H., Silveira, P. A., Mansell, A. S., Gaus, K. & Brodnicki, T. C., 1 Feb 2017, In : Molecular Immunology. 82, p. 19-33 15 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Distinct Campylobacter fetus lineages adapted as livestock pathogens and human pathobionts in the intestinal microbiota

Iraola, G., Forster, S. C., Kumar, N., Lehours, P., Bekal, S., García-Peña, F. J., Paolicchi, F., Morsella, C., Hotzel, H., Hsueh, P. R., Vidal, A., Lévesque, S., Yamazaki, W., Balzan, C., Vargas, A., Piccirillo, A., Chaban, B., Hill, J. E., Betancor, L., Collado, L. & 8 others, Truyers, I., Midwinter, A. C., Dagi, H. T., Mégraud, F., Calleros, L., Pérez, R., Naya, H. & Lawley, T. D., 1 Dec 2017, In : Nature Communications. 8, 1, 8 p., 1367.

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13 Citations (Scopus)

Effects of the central potassium ions on the G-quadruplex and stabilizer binding

Wang, Z. & Liu, J. P., 1 Mar 2017, In : Journal of Molecular Graphics and Modelling. 72, p. 168-177 10 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Endoscopic ultrasound-guided fine-needle aspirate-derived preclinical pancreatic cancer models reveal panitumumab sensitivity in KRAS wild-type tumors

Berry, W., Algar, E., Kumar, B., Desmond, C., Swan, M., Jenkins, B. J. & Croagh, D., 15 May 2017, In : International Journal of Cancer. 140, 10, p. 2331-2343 13 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Expression of Biglycan in First Trimester Chorionic Villous Sampling Placental Samples and Altered Function in Telomerase-Immortalized Microvascular Endothelial Cells

Chui, A., Gunatillake, T., Brennecke, S. P., Ignjatovic, V., Monagle, P. T., Whitelock, J. M., Van Zanten, D. E., Eijsink, J., Wang, Y., Deane, J., Borg, A. J., Stevenson, J., Erwich, J. J., Said, J. M. & Murthi, P., 1 Jun 2017, In : Arteriosclerosis, Thrombosis and Vascular Biology. 37, 6, p. 1168-1179 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Follistatin attenuates radiation-induced fibrosis in a murine model

Forrester, H. B., De Kretser, D. M., Leong, T., Hagekyriakou, J. & Sprung, C. N., 1 Mar 2017, In : PLoS ONE. 12, 3, 13 p., e0173788.

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6 Citations (Scopus)

Genetic variation at the Th2 immune gene IL13 is associated with IgE-mediated paediatric food allergy

Ashley, S. E., Tan, H. T. T., Peters, R., Allen, K. J., Vuillermin, P., Dharmage, S. C., Tang, M. L. K., Koplin, J., Lowe, A., Ponsonby, A. L., Molloy, T. J., Matheson, M. C., Saffery, R., Ellis, J. A., De Martino, D. & the HealthNuts team, 1 Aug 2017, In : Clinical and Experimental Allergy. 47, 8, p. 1032-1037 6 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)
14 Citations (Scopus)

Human Metapneumovirus Infection in Chronic Obstructive Pulmonary Disease: Impact of Glucocorticosteroids and Interferon

Kan-o, K., Sanchez-Ramirez, R., Macdonald, M. I., Rolph, M. S., Rudd, P. A., Spann, K. M., Mahalingam, S., Bardin, P. G. & Thomas, B. J., 15 May 2017, In : Journal of Infectious Diseases. 215, 10, p. 1536-1545 10 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Identification of a histone family gene signature for predicting the prognosis of cervical cancer patients

Li, X., Tian, R., Gao, H., Yang, Y., Williams, B. R. G., Gantier, M. P., McMillan, N. A. J., Xu, D., Hu, Y. & Gao, YE., 1 Dec 2017, In : Scientific Reports. 7, 1, 13 p., 16495.

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10 Citations (Scopus)

Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer

West, AC., Tang, K., Tye, H., Yu, L., Deng, N., Najdovska, M., Lin, S. J., Balic, JJ., Okochi-Takada, E., McGuirk, P., Keogh, B., McCormack, W., Bhathal, P. S., Reilly, M., Oshima, M., Ushijima, T., Tan, P. & Jenkins, B. J., 7 Sep 2017, In : Oncogene. 36, 36, p. 5134-5144 11 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Integrin-linked kinase expression in myeloid cells promotes inflammatory signaling during experimental colitis

Ahmed, A. U., Yim, H. C. H., Alorro, M. G., Ernst, M. & Williams, B. R. G., 15 Sep 2017, In : Journal of Immunology. 199, 6, p. 2128-2139 12 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Interferon epsilon promotes HIV restriction at multiple steps of viral replication

Garcia-Minambres, A., Eid, S. G., Mangan, N. E., Pade, C., Lim, S. S., Matthews, A. Y., de Weerd, N. A., Hertzog, P. J. & Johnson, M., May 2017, In : Immunology and Cell Biology. 95, 5, p. 478-483 6 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling

Balic, J. J., Garbers, C., Rose-John, S., Yu, L. & Jenkins, B. J., 1 Apr 2017, In : Cytokine. 92, p. 118-123 6 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Interleukin-11 induces preterm birth and modulates decidual inflammasome gene expression in mice

Winship, A. & Dimitriadis, E., Feb 2017, In : Placenta. 50, p. 99-101 3 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Interleukin-11 up-regulates endoplasmic reticulum stress induced target, PDIA4 in human first trimester placenta and in vivo in mice

Winship, A. L., Sorby, K., Correia, J., Rainczuk, A., Yap, J. & Dimitriadis, E., 1 May 2017, In : Placenta. 53, p. 92-100 9 p.

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3 Citations (Scopus)

Interleukin 6 Present in inflammatory ascites from advanced epithelial ovarian cancer patients promotes tumor necrosis factor receptor 2-expressing regulatory T cells

Kampan, N. C., Madondo, M. T., McNally, O. M., Stephens, A. N., Quinn, M. A. & Plebanski, M., 6 Nov 2017, In : Frontiers in Immunology. 8, NOV, 14 p., 1482.

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10 Citations (Scopus)

Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5

Menkhorst, E. M., Van Sinderen, M. L., Rainczuk, K., Cuman, C., Winship, A. & Dimitriadis, E., 1 Dec 2017, In : Scientific Reports. 7, 1, 11 p., 8690.

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3 Citations (Scopus)

In vivo evidence that RBM5 is a tumour suppressor in the lung

Jamsai, D., Watkins, D. N., O'Connor, A. E., Merriner, D. J., Gursoy, S., Bird, A. D., Kumar, B., Miller, A., Cole, T. J., Jenkins, B. J. & O'Bryan, M. K., 1 Dec 2017, In : Scientific Reports. 7, 1, 8 p., 15874.

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3 Citations (Scopus)

JNK activation of BIM promotes hepatic oxidative stress, steatosis, and insulin resistance in obesity

Litwak, S. A., Pang, L., Galic, S., Igoillo-Esteve, M., Stanley, W. J., Turatsinze, J. V., Loh, K., Thomas, H. E., Sharma, A., Trepo, E., Moreno, C., Gough, D. J., Eizirik, D. L., De Haan, J. B. & Gurzov, E. N., 1 Dec 2017, In : Diabetes. 66, 12, p. 2973-2986 14 p.

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7 Citations (Scopus)