Hudson Institute - Department of Molecular and Translational Science

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2019

Pre‐pubertal growth, muscle and fat accumulation in male and female sheep – relationships with metabolic hormone concentrations, timing of puberty and reproductive outcomes

Rosales Nieto, C. A., Ferguson, M. B., Briegel, J. R., Hedger, M., Martin, G. B. & Thompson, A. N., 24 Sep 2019, (Accepted/In press) In : Reproduction in Domestic Animals. 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Proteomic Insights into Endometrial Receptivity and Embryo‐Endometrial Epithelium Interaction for Implantation; Critical Determinants of Fertility

Evans, J., Hutchison, J. C., Salamonsen, L. & Greening, D. W., Dec 2019, (Accepted/In press) In : Proteomics. 29 p., e1900250.

Research output: Contribution to journalArticleResearchpeer-review

Rare variants in non-coding regulatory regions of the genome that affect gene expression in systemic lupus erythematosus

Jones, S. A., Cantsilieris, S., Fan, H., Cheng, Q., Russ, B. E., Tucker, E. J., Harris, J., Rudloff, I., Nold, M., Northcott, M., Dankers, W., Toh, A. E. J., White, S. J. & Morand, E. F., 1 Dec 2019, In : Scientific Reports. 9, 1, 9 p., 15433.

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Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection

Rosli, S., Kirby, F. J., Lawlor, K. E., Rainczuk, K., Drummond, G. R., Mansell, A. & Tate, M. D., Oct 2019, In : British Journal of Pharmacology. 176, 19, p. 3834-3844 11 p.

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2 Citations (Scopus)
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3 Citations (Scopus)

Review: Helicobacter: Inflammation, immunology, and vaccines

Lehours, P. & Ferrero, R. L., 1 Sep 2019, In : Helicobacter. 24, S1, 6 p., e12644.

Research output: Contribution to journalArticleOtherpeer-review

1 Citation (Scopus)

RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responses

Hayman, T. J., Hsu, A. C., Kolesnik, T. B., Dagley, L. F., Willemsen, J., Tate, M. D., Baker, P. J., Kershaw, N. J., Kedzierski, L., Webb, A. I., Wark, P. A., Kedzierska, K., Masters, S. L., Belz, G. T., Binder, M., Hansbro, P. M., Nicola, N. A. & Nicholson, S. E., Oct 2019, In : Immunology and Cell Biology. 97, 9, p. 840-852 13 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Salmonella effectors SseK1 and SseK3 target death domain proteins in the TNF and TRAIL signaling pathways

Newson, J., Scott, N. E., Chung, I. Y. W., Lung, T. W. F., Giogha, C., Gan, J., Wang, N., Strugnell, R., Brown, N. F., Cygler, M., Pearson, J. & Hartland, E., 1 Jun 2019, In : Molecular & Cellular Proteomics. 18, 6, p. 1138-1156 19 p.

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4 Citations (Scopus)

Serine-phosphorylated STAT3 promotes tumorigenesis via modulation of RNA polymerase transcriptional activity

Balic, J. J., Garama, D. J., Saad, M. I., Yu, L., West, A. C., West, A. J., Livis, T., Bhathal, P. S., Gough, D. J. & Jenkins, B. J., 15 Oct 2019, In : Cancer Research. 79, 20, p. 5272-5287 16 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Serum podocalyxin at 11–13 weeks of gestation in the prediction of small for gestational age neonates

Rolnik, D. L., Wang, Y., Hyett, J., Silva Costa, F. D. & Nie, G., 1 Jun 2019, In : Journal of Perinatology. 39, 6, p. 784-790 7 p.

Research output: Contribution to journalArticleResearchpeer-review

SIDT1 localizes to endolysosomes and mediates double-stranded RNA transport into the cytoplasm

Nguyen, T. A., Smith, B. R. C., Elgass, K. D., Creed, S. J., Cheung, S., Tate, M. D., Belz, G. T., Wicks, I. P., Masters, S. L. & Pang, K. C., 15 Jun 2019, In : Journal of Immunology. 202, 12, p. 3483-3492 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth

Shao, Y., Forster, S. C., Tsaliki, E., Vervier, K., Strang, A., Simpson, N., Kumar, N., Stares, M. D., Rodger, A., Brocklehurst, P., Field, N. & Lawley, T. D., 1 Oct 2019, In : Nature. 574, 7776, p. 117-121 5 p.

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10 Citations (Scopus)

Synergistic Combination of Polymyxin B and Enrofloxacin Induced Metabolic Perturbations in Extensive Drug-resistant Pseudomonas aeruginosa

Lin, Y-W., Han, M-L., Zhao, J., Zhu, Y., Rao, G., Forrest, A., Song, J., Kaye, K. S., Hertzog, P., Purcell, A., Creek, D., Zhou, T. Q., Velkov, T. & Li, J., 3 Oct 2019, In : Frontiers in Pharmacology. 10, 11 p., 1146.

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Targeting XIAP and PPARγ in granulosa cell tumors alters metabolic signaling

Leung, T. H., Rainczuk, A., Nguyen, T., Stephens, A., Silke, J., Fuller, P. J. & Chu, S., 5 Apr 2019, In : Journal of Proteome Research. 18, 4, p. 1691-1701 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The Single Nucleotide Polymorphism Mal-D96N Mice Provide New Insights into Functionality of Mal in TLR Immune Responses

Dowling, J. K., Tate, M. D., Rosli, S., Bourke, N. M., Bitto, N., Lauterbach, M. A., Cheung, S., Ve, T., Kobe, B., Golenbock, D. & Mansell, A., 15 Apr 2019, In : Journal of Immunology. 202, 8, p. 2384-2396 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

The transgenerational effects of oocyte mitochondrial supplementation

St. John, J. C., Makanji, Y., Johnson, J. L., Tsai, T. S., Lagondar, S., Rodda, F., Sun, X., Pangestu, M., Chen, P. & Temple-Smith, P., 1 Dec 2019, In : Scientific Reports. 9, 1, 12 p., 6694.

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4 Citations (Scopus)

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2

Liu, Y. D., Yu, L., Ying, L., Balic, J., Gao, H., Deng, N. T., West, A., Yan, F., Ji, C. B., Gough, D., Tan, P., Jenkins, B. J. & Li, J. K., 15 Jun 2019, In : International Journal of Cancer. 144, 12, p. 3056-3069 14 p.

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4 Citations (Scopus)

Transfusion or Timing: The Role of Blood Volume in Delayed Cord Clamping During the Cardiovascular Transition at Birth

Stenning, F. J., Hooper, S. B., Kluckow, M., Crossley, K. J., Gill, A. W., Wallace, E. M., te Pas, A. B., LaRosa, D. & Polglase, G. R., 9 Oct 2019, In : Frontiers in Pediatrics. 7, 10 p., 405.

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Tumor inherent interferon regulators as biomarkers of long-term chemotherapeutic response in TNBC

Brockwell, N. K., Rautela, J., Owen, K. L., Gearing, L. J., Deb, S., Harvey, K., Spurling, A., Zanker, D., Chan, C. L., Cumming, H. E., Deng, N., Zakhour, J. M., Duivenvoorden, H. M., Robinson, T., Harris, M., White, M., Fox, J., Ooi, C., Kumar, B., Thomson, J. & 7 others, Potasz, N., Swarbrick, A., Hertzog, P., Molloy, T. J., O’Toole, S., Ganju, V. & Parker, B. S., 29 Aug 2019, In : NPJ Precision Oncology. 3, 13 p., 21.

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Unique transcriptional architecture in airway epithelial cells and macrophages shapes distinct responses following influenza virus infection Ex vivo

Ma, J. Z., Ng, W. C., Zappia, L., Gearing, L. J., Olshansky, M., Pham, K., Cheong, K., Hsu, A., Turner, S. J., Wijburg, O., Londrigan, S. L., Brooks, A. G. & Reading, P. C., 1 Mar 2019, In : Journal of Virology. 93, 6, 22 p., e01986-18.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Uterine SOX17: a key player in human endometrial receptivity and embryo implantation

Kinnear, S., Salamonsen, L. A., Francois, M., Harley, V. R. & Evans, J., 29 Oct 2019, In : Scientific Reports. 9, 1, 10 p., 15495.

Research output: Contribution to journalArticleResearchpeer-review

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2018

(−)-Epigallocatechin-3-gallate and EZH2 inhibitor GSK343 have similar inhibitory effects and mechanisms of action on colorectal cancer cells

Ying, L., Yan, F., Williams, B. R. G., Xu, P., Li, X., Zhao, Y., Hu, Y., Wang, Y., Xu, D. & Dai, J., 1 Jan 2018, In : Clinical and Experimental Pharmacology and Physiology. 45, 1, p. 58-67 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

A Comparison of Two Ovine Lumbar Intervertebral Disc Injury Models for the Evaluation and Development of Novel Regenerative Therapies

Daly, C. D., Ghosh, P., Badal, T., Shimmon, R., Jenkin, G., Oehme, D., Cooper-White, J., Sher, I., Chandra, R. V. & Goldschlager, T., 1 Dec 2018, In : Global Spine Journal. 8, 8, p. 847-859 13 p.

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Activation of ERBB4 in glioblastoma can contribute to increased tumorigenicity and influence therapeutic response

Donoghue, J. F., Kerr, L. T., Alexander, N. W., Greenall, S. A., Longano, A. B., Gottardo, N. G., Wang, R., Tabar, V., Adams, T. E., Mischel, P. S. & Johns, T. G., 1 Aug 2018, In : Cancers. 10, 8, 16 p., 243.

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6 Citations (Scopus)

A guide to miRNAs in inflammation and innate immune responses

Nejad, C., Stunden, H. J. & Gantier, M. P., 24 Apr 2018, In : FEBS Journal. 285, 20, p. 3695-3716 22 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

An anti-gdnf family receptor alpha 1 (gfra1 antibody–drug conjugate for the treatment of hormone receptor–positive breast cancer

Bhakta, S., Crocker, L. M., Chen, Y., Hazen, M., Schutten, M. M., Li, D., Kuijl, C., Ohri, R., Zhong, F., Poon, K. A., Go, M. A. T., Cheng, E., Piskol, R., Firestein, R., Fourie-O'Donohue, A., Kozak, K. R., Raab, H., Hongo, J. A., Sampath, D., Dennis, M. S. & 3 others, Scheller, R. H., Polakis, P. & Junutula, J. R., 1 Mar 2018, In : Molecular Cancer Therapeutics. 17, 3, p. 638-649 12 p.

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14 Citations (Scopus)

A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer

Alamgeer, M., Neil Watkins, D., Banakh, I., Kumar, B., Gough, D. J., Markman, B. & Ganju, V., 1 Apr 2018, In : Investigational New Drugs. 36, 2, p. 288-298 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors

Endersby, R., Whitehouse, J., Hii, H., Greenall, S. A., Johns, T. G. & Gottardo, N. G., 1 May 2018, In : Neoplasia. 20, 5, p. 432-442 11 p.

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2 Citations (Scopus)
3 Citations (Scopus)

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

Faridi, P., Li, C., Ramarathinam, S. H., Vivian, J. P., Illing, P. T., Mifsud, N. A., Ayala, R., Song, J., Gearing, L. J., Hertzog, P. J., Ternette, N., Rossjohn, J., Croft, N. P. & Purcell, A. W., 12 Oct 2018, In : Science Immunology. 3, 28, 12 p., eaar3947.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Autoantibodies against HSF1 and CCDC155 as biomarkers of early-Stage, high-Grade serous ovarian cancer

Wilson, A. L., Moffitt, L. R., Duffield, N., Rainczuk, A., Jobling, T. W., Plebanski, M. & Stephens, A. N., 1 Feb 2018, In : Cancer Epidemiology Biomarkers and Prevention. 27, 2, p. 183-192 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Being born too small and too early may alter sleep in childhood

Yiallourou, S. R., Arena, B. C., Wallace, E. M., Odoi, A., Hollis, S., Weichard, A. & Horne, R. S. C., 1 Feb 2018, In : Sleep. 41, 2, 11 p., zsx193.

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6 Citations (Scopus)

Carotenoid composition of a New Zealand (Evechinus chloroticus) and an Australian (Heliocidaris erythrogramma) sea urchin in relation to gonad colour

Brewster, J., Garama, D., Lamare, M. & Carne, A., 1 Aug 2018, In : Aquaculture Research. 49, 8, p. 2751-2762 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Clinical utility of a STAT3-regulated miRNA-200 family signature with prognostic potential in early gastric cancer

Yu, L., Wu, D., Gao, H., Balic, J. J., Tsykin, A., Han, T. S., Liu, Y. D., Kennedy, C. L., Li, J. K., Mao, J. Q., Tan, P., Oshima, M., Goodall, G. J. & Jenkins, B. J., 15 Mar 2018, In : Clinical Cancer Research. 24, 6, p. 1459-1472 14 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Concurrent host-pathogen transcriptional responses in a clostridium perfringens murine myonecrosis infection

Low, L-Y., Harrison, P. F., Gould, J., Powell, D. R., Choo, J. M., Forster, S. C., Chapman, R., Gearing, L. J., Cheung, J. K., Hertzog, P. & Rood, J. I., 1 Mar 2018, In : mBio. 9, 2, 15 p., e00473-18.

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7 Citations (Scopus)

Controlling the Effective Oxygen Tension Experienced by Cells Using a Dynamic Culture Technique for Hematopoietic Ex Vivo Expansion

Tiwari, A., Wong, C., Nekkanti, L. P., Deane, J. A., McDonald, C., Li, J., Pham, Y., Sutherland, A. E., Jenkin, G. & Kirkland, M., 28 Feb 2018, In : Current Protocols in Stem Cell Biology. 44, 1, p. 2A.11.1-2A.11.13 13 p.

Research output: Contribution to journalArticleOtherpeer-review

Culturing of female bladder bacteria reveals an interconnected urogenital microbiota

Thomas-White, K., Forster, S. C., Kumar, N., Van Kuiken, M., Putonti, C., Stares, M. D., Hilt, E. E., Price, T. K., Wolfe, A. J. & Lawley, T. D., 1 Dec 2018, In : Nature Communications. 9, 1, 7 p., 1557.

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32 Citations (Scopus)

Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer

Leong, T. L., Gayevskiy, V., Steinfort, D. P., De Massy, M. R., Gonzalez-Rajal, A., Marini, K. D., Stone, E., Chin, V., Havryk, A., Plit, M., Irving, L. B., Jennings, B. R., McCloy, R. A., Jayasekara, W. S. N., Alamgeer, M., Boolell, V., Field, A., Russell, P. A., Kumar, B., Gough, D. J. & 8 others, Szczepny, A., Ganju, V., Rossello, F. J., Cain, J. E., Papenfuss, A. T., Asselin-Labat, M. L., Cowley, M. J. & Watkins, D. N., 7 Mar 2018, In : Oncogene. 38, 10, p. 1661-1675 15 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Defining the distinct, intrinsic properties of the novel type i interferon, IFNϵ

Stifter, S. A., Matthews, A. Y., Mangan, N. E., Fung, K. Y., Drew, A., Tate, M. D., Soares Da Costa, T. P., Hampsey, D., Mayall, J., Hansbro, P. M., Minambres, A. G., Eid, S. G., Mak, J., Scoble, J., Lovrecz, G., DeWeerd, N. A. & Hertzog, P. J., 1 Jan 2018, In : Journal of Biological Chemistry. 293, 9, p. 3168-3179 12 p.

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9 Citations (Scopus)

Differential expression profiles of conserved Snail transcription factors in the mouse testis

Micati, D. J., Hime, G. R., McLaughlin, E. A., Abud, H. E. & Loveland, K. L., 1 Mar 2018, In : Andrology. 6, 2, p. 362-373 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3

Greenall, S. A., Donoghue, J., Johns, T. G. & Adams, T. E., 1 Aug 2018, In : Translational Oncology. 11, 4, p. 971-978 8 p.

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2 Citations (Scopus)

Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine

Sandow, J. J., Rainczuk, A., Infusini, G., Makanji, M., Bilandzic, M., Wilson, A. L., Fairweather, N., Stanton, P. G., Garama, D., Gough, D., Jobling, T. W., Webb, A. I. & Stephens, A. N., 1 May 2018, In : Proteomics - Clinical Applications. 12, 3, 10 p., 1700135.

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12 Citations (Scopus)

Dysregulation and dislocation of SFPQ disturbed DNA organization in Alzheimer's disease and frontotemporal dementia

Lu, J., Shu, R. & Zhu, Y., 23 Jan 2018, In : Journal of Alzheimer's Disease. 61, 4, p. 1311-1321 11 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Epigenomic drugs and the germline: Collateral damage in the home of heritability?

Western, P. S., 15 Jun 2018, In : Molecular and Cellular Endocrinology. 468, p. 121-133 13 p.

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5 Citations (Scopus)

Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis

Saeidi, S., Shapouri, F., De Iongh, R. U., Casagranda, F., Sutherland, J. M., Western, P. S., McLaughlin, E. A., Familari, M. & Hime, G. R., 1 Jan 2018, In : PLoS ONE. 13, 1, 15 p., e0190925.

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1 Citation (Scopus)

Extracellular vesicles in human reproduction in health and disease

Simon, C., Greening, D. W., Balaguer, N., Salamonsen, LA. & Vilella, F., Jun 2018, In : Endocrine Reviews. 39, 3, p. 292-332 41 p.

Research output: Contribution to journalArticleOtherpeer-review

Formyl peptide receptor-2 is decreased in foetal growth restriction and contributes to placental dysfunction

Lappas, M., McCracken, S., McKelvey, K., Lim, R., James, J., Roberts, C. T., Fournier, T., Alfaidy, N., Powell, K. L., Borg, A. J., Morris, J. M., Leaw, B., Singh, H., Ebeling, P. R., Wallace, E. M., Parry, L. J., Dimitriadis, E. & Murthi, P., 1 Feb 2018, In : Molecular Human Reproduction. 24, 2, p. 94-109 16 p., gax067.

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2 Citations (Scopus)

Galectin‑7 is elevated in endometrioid (type I) endometrial cancer and promotes cell migration

Menkhorst, E., Griffiths, M., van Sinderen, M., Rainczuk, K., Niven, K. & Dimitriadis, E., 1 Oct 2018, In : Oncology Letters. 16, 4, p. 4721-4728 8 p.

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2 Citations (Scopus)

Genetic variation affecting DNA methylation and the human imprinting disorder, Beckwith-Wiedemann syndrome

Dagar, V., Hutchison, W., Muscat, A., Krishnan, A., Hoke, D., Buckle, A., Siswara, P., Amor, D. J., Mann, J., Pinner, J., Colley, A., Wilson, M., Sachdev, R., McGillivray, G., Edwards, M., Kirk, E., Collins, F., Jones, K., Taylor, J., Hayes, I. & 14 others, Thompson, E., Barnett, C., Haan, E., Freckmann, M-L., Turner, A., White, S., Kamien, B., Ma, A., Mackenzie, F., Baynam, G., Kiraly-Borri, C., Field, M., Dudding-Byth, T. & Algar, E., 30 Aug 2018, In : Clinical Epigenetics. 10, 1, 13 p., 114.

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3 Citations (Scopus)

Haemodynamic effects of umbilical cord milking in premature sheep during the neonatal transition

Blank, D. A., Polglase, G. R., Kluckow, M., Gill, A. W., Crossley, K. J., Moxham, A., Rodgers, K., Zahra, V., Inocencio, I., Stenning, F., Larosa, D. A., Davis, P. G. & Hooper, S. B., 1 Nov 2018, In : Archives of Disease in Childhood: Fetal and Neonatal Edition. 103, 6, p. F539-F546 8 p.

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26 Citations (Scopus)